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CL2014001776A1 - Composicion farmaceutica topica que comprende: a) bexaroteno, b) al menos 1 corticosteroide y c) un portador o vehiculo; uso para el tratamiento o la prevencion de trastornos de la piel, como psoriasis. - Google Patents

Composicion farmaceutica topica que comprende: a) bexaroteno, b) al menos 1 corticosteroide y c) un portador o vehiculo; uso para el tratamiento o la prevencion de trastornos de la piel, como psoriasis.

Info

Publication number
CL2014001776A1
CL2014001776A1 CL2014001776A CL2014001776A CL2014001776A1 CL 2014001776 A1 CL2014001776 A1 CL 2014001776A1 CL 2014001776 A CL2014001776 A CL 2014001776A CL 2014001776 A CL2014001776 A CL 2014001776A CL 2014001776 A1 CL2014001776 A1 CL 2014001776A1
Authority
CL
Chile
Prior art keywords
bexarotene
corticosteroid
psoriasis
prevention
carrier
Prior art date
Application number
CL2014001776A
Other languages
English (en)
Inventor
Fritjof Evers
Henning Mallwitz
Christoph Willers
Sabine Fielhauer
Hagen Trommer
Original Assignee
Almirall Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48781060&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2014001776(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP12000077.3A external-priority patent/EP2612665A1/en
Application filed by Almirall Sa filed Critical Almirall Sa
Publication of CL2014001776A1 publication Critical patent/CL2014001776A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CL2014001776A 2012-01-09 2014-07-02 Composicion farmaceutica topica que comprende: a) bexaroteno, b) al menos 1 corticosteroide y c) un portador o vehiculo; uso para el tratamiento o la prevencion de trastornos de la piel, como psoriasis. CL2014001776A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP12000077.3A EP2612665A1 (en) 2012-01-09 2012-01-09 Topical pharmaceutical compositions comprising bexarotene and a corticosteroide
US201261585786P 2012-01-12 2012-01-12
US201261598095P 2012-02-13 2012-02-13
EP12000909 2012-02-13

Publications (1)

Publication Number Publication Date
CL2014001776A1 true CL2014001776A1 (es) 2014-08-29

Family

ID=48781060

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2014001776A CL2014001776A1 (es) 2012-01-09 2014-07-02 Composicion farmaceutica topica que comprende: a) bexaroteno, b) al menos 1 corticosteroide y c) un portador o vehiculo; uso para el tratamiento o la prevencion de trastornos de la piel, como psoriasis.

Country Status (21)

Country Link
US (1) US20140349981A1 (es)
EP (1) EP2802321A1 (es)
JP (1) JP2015503573A (es)
KR (1) KR20140107370A (es)
CN (1) CN104053437A (es)
AU (1) AU2012365658A1 (es)
BR (1) BR112014015578A8 (es)
CA (1) CA2857207A1 (es)
CL (1) CL2014001776A1 (es)
CO (1) CO7000772A2 (es)
CR (1) CR20140326A (es)
EA (1) EA201400806A1 (es)
GT (1) GT201400146A (es)
HK (1) HK1198423A1 (es)
IL (1) IL232765A0 (es)
MX (1) MX2014007300A (es)
PE (1) PE20142375A1 (es)
PH (1) PH12014501573A1 (es)
SG (1) SG11201403762PA (es)
WO (1) WO2013104399A1 (es)
ZA (1) ZA201403483B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9963439B2 (en) 2013-08-20 2018-05-08 University Of Washington Through Its Center For Commercialization Specific inhibitors of cytochrome P450 26 retinoic acid hydroxylase
LT3310389T (lt) 2015-06-18 2020-11-10 Bausch Health Ireland Limited Vietinio vartojimo kompozicijos, apimančios kortikosteroidą ir retinoidą, skirtos psoriazės gydymui
US11311482B2 (en) 2017-05-12 2022-04-26 Bausch Health Us, Llc Topical compositions and methods for treating skin diseases
JP2022508512A (ja) * 2018-09-28 2022-01-19 ジョエル スタディン ステロイド及び巨大分子の経穴送達
WO2020084548A1 (en) * 2018-10-26 2020-04-30 Viramal Limited Mucoadhesive gel composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2282682C (en) 1997-02-20 2008-08-19 Allergan Sales, Inc. Tazarotene and corticosteroid treatment for psoriasis
CN1210034C (zh) * 2002-12-06 2005-07-13 重庆华邦制药股份有限公司 治疗银屑病的药物组合物
CN1210035C (zh) 2003-09-29 2005-07-13 中国医学科学院皮肤病研究所 治疗银屑病的复方外用药物

Also Published As

Publication number Publication date
AU2012365658A1 (en) 2014-07-03
EA201400806A1 (ru) 2015-02-27
PH12014501573A1 (en) 2014-10-08
MX2014007300A (es) 2014-07-28
HK1198423A1 (zh) 2015-04-24
US20140349981A1 (en) 2014-11-27
WO2013104399A1 (en) 2013-07-18
EP2802321A1 (en) 2014-11-19
PE20142375A1 (es) 2015-01-11
BR112014015578A8 (pt) 2017-07-04
CN104053437A (zh) 2014-09-17
CO7000772A2 (es) 2014-07-21
SG11201403762PA (en) 2014-07-30
ZA201403483B (en) 2015-06-24
CR20140326A (es) 2015-01-16
CA2857207A1 (en) 2013-07-18
IL232765A0 (en) 2014-07-31
JP2015503573A (ja) 2015-02-02
KR20140107370A (ko) 2014-09-04
BR112014015578A2 (pt) 2017-06-13
GT201400146A (es) 2015-10-12

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