CL2013003785A1 - Uso de necrostatina-1 para el tratamiento de la degeneracion axonal inducida por daños agudos y cronicos - Google Patents
Uso de necrostatina-1 para el tratamiento de la degeneracion axonal inducida por daños agudos y cronicosInfo
- Publication number
- CL2013003785A1 CL2013003785A1 CL2013003785A CL2013003785A CL2013003785A1 CL 2013003785 A1 CL2013003785 A1 CL 2013003785A1 CL 2013003785 A CL2013003785 A CL 2013003785A CL 2013003785 A CL2013003785 A CL 2013003785A CL 2013003785 A1 CL2013003785 A1 CL 2013003785A1
- Authority
- CL
- Chile
- Prior art keywords
- necrostatin
- acute
- treatment
- axonal degeneration
- chronic damage
- Prior art date
Links
- TXUWMXQFNYDOEZ-UHFFFAOYSA-N 5-(1H-indol-3-ylmethyl)-3-methyl-2-sulfanylidene-4-imidazolidinone Chemical compound O=C1N(C)C(=S)NC1CC1=CNC2=CC=CC=C12 TXUWMXQFNYDOEZ-UHFFFAOYSA-N 0.000 title 1
- 230000009692 acute damage Effects 0.000 title 1
- 230000003376 axonal effect Effects 0.000 title 1
- 230000009693 chronic damage Effects 0.000 title 1
- 230000007850 degeneration Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CL2013003785A CL2013003785A1 (es) | 2013-12-30 | 2013-12-30 | Uso de necrostatina-1 para el tratamiento de la degeneracion axonal inducida por daños agudos y cronicos |
| ARP140104692A AR098778A1 (es) | 2013-12-30 | 2014-12-16 | Método y uso de necrostatina-1 para el tratamiento de la degeneración axonal inducida por daños agudos y crónicos |
| PCT/CL2014/000084 WO2015100511A1 (es) | 2013-12-30 | 2014-12-23 | Metodo y uso de necrostatina-1 para el tratamiento de la degeneracion axonal inducida por danos agudos y cr0nicos |
| UY0001035921A UY35921A (es) | 2013-12-30 | 2014-12-24 | Necrostatina-1 y derivados como retardadores de la degeneración axonal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CL2013003785A CL2013003785A1 (es) | 2013-12-30 | 2013-12-30 | Uso de necrostatina-1 para el tratamiento de la degeneracion axonal inducida por daños agudos y cronicos |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2013003785A1 true CL2013003785A1 (es) | 2014-07-11 |
Family
ID=53492873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2013003785A CL2013003785A1 (es) | 2013-12-30 | 2013-12-30 | Uso de necrostatina-1 para el tratamiento de la degeneracion axonal inducida por daños agudos y cronicos |
Country Status (4)
| Country | Link |
|---|---|
| AR (1) | AR098778A1 (es) |
| CL (1) | CL2013003785A1 (es) |
| UY (1) | UY35921A (es) |
| WO (1) | WO2015100511A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11382889B2 (en) | 2018-04-19 | 2022-07-12 | Institut D'investigació Biomèdica De Bellvitge (Idibell) | NRF2 activators for the prevention and/or treatment of axonal degeneration |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2633500A1 (en) * | 2005-12-20 | 2007-07-05 | President And Fellows Of Harvard College | Compounds, screens, and methods of treatment |
| US20140357570A1 (en) * | 2011-10-21 | 2014-12-04 | Massachusetts Eye And Ear Infirmary | Compositions comprising necrosis inhibitors, such as necrostatins, alone or in combination, for promoting axon regeneration and nerve function, thereby treating cns disorders |
-
2013
- 2013-12-30 CL CL2013003785A patent/CL2013003785A1/es unknown
-
2014
- 2014-12-16 AR ARP140104692A patent/AR098778A1/es unknown
- 2014-12-23 WO PCT/CL2014/000084 patent/WO2015100511A1/es not_active Ceased
- 2014-12-24 UY UY0001035921A patent/UY35921A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015100511A1 (es) | 2015-07-09 |
| AR098778A1 (es) | 2016-06-15 |
| UY35921A (es) | 2015-06-30 |
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