CL2013003435A1 - Process of preparation of estetrol intermediaries using palladium catalysts and acylating or silylating protecting groups; and use of said process to prepare estetrol. - Google Patents
Process of preparation of estetrol intermediaries using palladium catalysts and acylating or silylating protecting groups; and use of said process to prepare estetrol.Info
- Publication number
- CL2013003435A1 CL2013003435A1 CL2013003435A CL2013003435A CL2013003435A1 CL 2013003435 A1 CL2013003435 A1 CL 2013003435A1 CL 2013003435 A CL2013003435 A CL 2013003435A CL 2013003435 A CL2013003435 A CL 2013003435A CL 2013003435 A1 CL2013003435 A1 CL 2013003435A1
- Authority
- CL
- Chile
- Prior art keywords
- estetrol
- silylating
- intermediaries
- acylating
- prepare
- Prior art date
Links
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 title 2
- AJIPIJNNOJSSQC-NYLIRDPKSA-N estetrol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H]([C@H](O)[C@@H]4O)O)[C@@H]4[C@@H]3CCC2=C1 AJIPIJNNOJSSQC-NYLIRDPKSA-N 0.000 title 2
- 229950009589 estetrol Drugs 0.000 title 2
- 239000003054 catalyst Substances 0.000 title 1
- 229910052763 palladium Inorganic materials 0.000 title 1
- 125000006239 protecting group Chemical group 0.000 title 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161492300P | 2011-06-01 | 2011-06-01 | |
| EP11168561 | 2011-06-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2013003435A1 true CL2013003435A1 (en) | 2014-08-01 |
Family
ID=65657112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2013003435A CL2013003435A1 (en) | 2011-06-01 | 2013-11-29 | Process of preparation of estetrol intermediaries using palladium catalysts and acylating or silylating protecting groups; and use of said process to prepare estetrol. |
Country Status (1)
| Country | Link |
|---|---|
| CL (1) | CL2013003435A1 (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11452733B2 (en) | 2018-04-19 | 2022-09-27 | Estetra Sprl | Compounds and their uses for alleviating menopause-associated symptoms |
| US11484539B2 (en) | 2018-04-19 | 2022-11-01 | Estetra Sprl | Compounds and their uses for alleviating menopause-associated symptoms |
| US11896602B2 (en) | 2016-08-05 | 2024-02-13 | Estetra Srl | Method for preventing pregnancy |
| US11964055B2 (en) | 2015-06-18 | 2024-04-23 | Estetra Srl | Orodispersible dosage unit containing an estetrol component |
| US12458649B2 (en) | 2020-04-16 | 2025-11-04 | Estetra Srl | Contraceptive compositions with reduced adverse effects |
-
2013
- 2013-11-29 CL CL2013003435A patent/CL2013003435A1/en unknown
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11964055B2 (en) | 2015-06-18 | 2024-04-23 | Estetra Srl | Orodispersible dosage unit containing an estetrol component |
| US11896602B2 (en) | 2016-08-05 | 2024-02-13 | Estetra Srl | Method for preventing pregnancy |
| US11452733B2 (en) | 2018-04-19 | 2022-09-27 | Estetra Sprl | Compounds and their uses for alleviating menopause-associated symptoms |
| US11484539B2 (en) | 2018-04-19 | 2022-11-01 | Estetra Sprl | Compounds and their uses for alleviating menopause-associated symptoms |
| US11666585B2 (en) | 2018-04-19 | 2023-06-06 | Estetra Srl | Compounds and their uses for alleviating menopause-associated symptoms |
| US12390478B2 (en) | 2018-04-19 | 2025-08-19 | Estetra Srl | Compounds and their uses for alleviating menopause-associated symptoms |
| US12458651B2 (en) | 2018-04-19 | 2025-11-04 | Estetra Srl | Compounds and their uses for alleviating menopause-associated symptoms |
| US12458649B2 (en) | 2020-04-16 | 2025-11-04 | Estetra Srl | Contraceptive compositions with reduced adverse effects |
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