CL2013003160A1 - Compounds derived from 4h-chromen-4-one modulators of the protein kinase pi3k; intermediary compounds; pharmaceutical composition that includes them; and useful in the treatment of cancer, anti-inflammatory agents, immunosuppressants, steroids, analgesics, leukemia, among others. - Google Patents
Compounds derived from 4h-chromen-4-one modulators of the protein kinase pi3k; intermediary compounds; pharmaceutical composition that includes them; and useful in the treatment of cancer, anti-inflammatory agents, immunosuppressants, steroids, analgesics, leukemia, among others.Info
- Publication number
- CL2013003160A1 CL2013003160A1 CL2013003160A CL2013003160A CL2013003160A1 CL 2013003160 A1 CL2013003160 A1 CL 2013003160A1 CL 2013003160 A CL2013003160 A CL 2013003160A CL 2013003160 A CL2013003160 A CL 2013003160A CL 2013003160 A1 CL2013003160 A1 CL 2013003160A1
- Authority
- CL
- Chile
- Prior art keywords
- compounds
- chromen
- immunosuppressants
- analgesics
- steroids
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 229940035676 analgesics Drugs 0.000 title abstract 2
- 239000000730 antalgic agent Substances 0.000 title abstract 2
- 239000002260 anti-inflammatory agent Substances 0.000 title abstract 2
- 229940121363 anti-inflammatory agent Drugs 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- OTAFHZMPRISVEM-UHFFFAOYSA-N chromone Chemical compound C1=CC=C2C(=O)C=COC2=C1 OTAFHZMPRISVEM-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003444 immunosuppressant agent Drugs 0.000 title abstract 2
- 239000003018 immunosuppressive agent Substances 0.000 title abstract 2
- 208000032839 leukemia Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000003431 steroids Chemical class 0.000 title abstract 2
- 102000001253 Protein Kinase Human genes 0.000 title 1
- 108060006633 protein kinase Proteins 0.000 title 1
- 102000038030 PI3Ks Human genes 0.000 abstract 1
- 108091007960 PI3Ks Proteins 0.000 abstract 1
Classifications
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- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
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Abstract
La presente invención proporciona compuestos derivados de 4H-cromen-4-ona moduladores de la proteína cinasa PI3K, de formula I; compuestos intermediarios; composición farmacéutica que los comprende; y útiles en el tratamiento del cáncer, agentes antinflamatorios, inmunosupresores, esteroides, analgésicos, leucemia, entre otros.The present invention provides compounds derived from 4H-chromen-4-one modulators of the PI3K protein kinase, of formula I; intermediary compounds; pharmaceutical composition comprising them; and useful in the treatment of cancer, anti-inflammatory agents, immunosuppressants, steroids, analgesics, leukemia, among others.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1542CH2011 | 2011-05-04 | ||
| IN81CH2012 | 2012-01-09 |
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| Publication Number | Publication Date |
|---|---|
| CL2013003160A1 true CL2013003160A1 (en) | 2014-09-26 |
Family
ID=46147717
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2013003160A CL2013003160A1 (en) | 2011-05-04 | 2013-11-04 | Compounds derived from 4h-chromen-4-one modulators of the protein kinase pi3k; intermediary compounds; pharmaceutical composition that includes them; and useful in the treatment of cancer, anti-inflammatory agents, immunosuppressants, steroids, analgesics, leukemia, among others. |
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