CL2013001037A1 - Polipeptido gb de citomegalovirus (cmv) que comprende al menos un dominio extracelular de proteina gb; composicion inmunogénica que comprende el polipeptido gb de cmv; metodo para producir respuesta inmune contra cmv. - Google Patents
Polipeptido gb de citomegalovirus (cmv) que comprende al menos un dominio extracelular de proteina gb; composicion inmunogénica que comprende el polipeptido gb de cmv; metodo para producir respuesta inmune contra cmv.Info
- Publication number
- CL2013001037A1 CL2013001037A1 CL2013001037A CL2013001037A CL2013001037A1 CL 2013001037 A1 CL2013001037 A1 CL 2013001037A1 CL 2013001037 A CL2013001037 A CL 2013001037A CL 2013001037 A CL2013001037 A CL 2013001037A CL 2013001037 A1 CL2013001037 A1 CL 2013001037A1
- Authority
- CL
- Chile
- Prior art keywords
- cmv
- polypeptide
- cytomegalovirus
- protein
- immune response
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title 2
- 102000004196 processed proteins & peptides Human genes 0.000 title 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 2
- 241000701022 Cytomegalovirus Species 0.000 title 1
- 230000028993 immune response Effects 0.000 title 1
- 230000002163 immunogen Effects 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/03—Herpetoviridae, e.g. pseudorabies virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/03—Herpetoviridae, e.g. pseudorabies virus
- C07K14/04—Varicella-zoster virus
- C07K14/045—Cytomegalovirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39341310P | 2010-10-15 | 2010-10-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2013001037A1 true CL2013001037A1 (es) | 2013-08-30 |
Family
ID=44789497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2013001037A CL2013001037A1 (es) | 2010-10-15 | 2013-04-15 | Polipeptido gb de citomegalovirus (cmv) que comprende al menos un dominio extracelular de proteina gb; composicion inmunogénica que comprende el polipeptido gb de cmv; metodo para producir respuesta inmune contra cmv. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20130216613A1 (es) |
| EP (1) | EP2627352B1 (es) |
| JP (1) | JP6138047B2 (es) |
| KR (1) | KR20130140009A (es) |
| CN (1) | CN103237560B (es) |
| AR (1) | AR083454A1 (es) |
| AU (1) | AU2011315447A1 (es) |
| BR (1) | BR112013008624B1 (es) |
| CA (1) | CA2813522C (es) |
| CL (1) | CL2013001037A1 (es) |
| CO (1) | CO6741153A2 (es) |
| CR (1) | CR20130191A (es) |
| DO (1) | DOP2013000080A (es) |
| ES (1) | ES2635014T3 (es) |
| IL (1) | IL225667A0 (es) |
| MA (1) | MA34802B1 (es) |
| MX (1) | MX2013004149A (es) |
| PH (1) | PH12013500724A1 (es) |
| SG (1) | SG189176A1 (es) |
| TW (1) | TW201305190A (es) |
| WO (1) | WO2012049317A2 (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011053798A2 (en) * | 2009-10-30 | 2011-05-05 | The Administrators Of The Tulane Educational Fund | Peptide compositions and methods for inhibiting herpesvirus infection |
| HRP20211015T1 (hr) | 2013-12-03 | 2021-10-01 | Hookipa Biotech Gmbh | Cjepivo protiv citomegalovirusa (cmv) |
| CN106102769A (zh) * | 2013-12-11 | 2016-11-09 | 促进军事医学的亨利·M·杰克逊基金会公司 | 人疱疹病毒三聚糖蛋白B、包含三聚gB的蛋白复合体及其作为疫苗的用途 |
| EP3031822A1 (en) * | 2014-12-08 | 2016-06-15 | Novartis AG | Cytomegalovirus antigens |
| US10611800B2 (en) | 2016-03-11 | 2020-04-07 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| WO2017153954A1 (en) * | 2016-03-11 | 2017-09-14 | Pfizer Inc. | Human cytomegalovirus gb polypeptide |
| CN106119286A (zh) * | 2016-08-10 | 2016-11-16 | 吴江近岸蛋白质科技有限公司 | 表达载体及其高效表达和制备人胱抑素c蛋白的方法 |
| BR112019020853A2 (pt) | 2017-04-04 | 2020-05-12 | Avidea Technologies, Inc. | Vacinas à base de peptídeo, métodos de fabricação e usos das mesmas para induzir uma resposta imune |
| BR112020004747A2 (pt) | 2017-09-13 | 2020-09-24 | Sanofi Pasteur | composição imunogênica de citomegalovírus humano |
| WO2020085457A1 (ja) | 2018-10-25 | 2020-04-30 | Kmバイオロジクス株式会社 | 改変CMV gBタンパク質及びこれを含むCMVワクチン |
| JP7179872B2 (ja) * | 2018-12-10 | 2022-11-29 | Kmバイオロジクス株式会社 | サイトメガロウイルスの先天性感染を予防又は治療するためのワクチン |
| US11629172B2 (en) | 2018-12-21 | 2023-04-18 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| CN109627294B (zh) * | 2018-12-29 | 2020-10-09 | 四川大学 | 一种正确折叠的重组狂犬病毒g蛋白胞外段及其潜在应用 |
| EP4004018A1 (en) | 2019-07-24 | 2022-06-01 | GlaxoSmithKline Biologicals SA | Modified human cytomegalovirus proteins |
| US20230234992A1 (en) | 2020-06-05 | 2023-07-27 | Glaxosmithkline Biologicals Sa | Modified betacoronavirus spike proteins |
| WO2021250626A2 (en) | 2020-06-12 | 2021-12-16 | Glaxosmithkline Biologicals Sa | Dock tag system |
| US20230303637A1 (en) | 2020-06-12 | 2023-09-28 | Glaxosmithkline Biologicals Sa | Gbs ferritin nanoparticles |
| TWI810589B (zh) | 2020-06-21 | 2023-08-01 | 美商輝瑞股份有限公司 | 人巨細胞病毒糖蛋白B(gB)多肽 |
| EP4237085A1 (en) | 2020-10-28 | 2023-09-06 | Sanofi Pasteur | Liposomes containing tlr4 agonist, preparation and uses thereof |
| JP2024535054A (ja) * | 2021-09-16 | 2024-09-26 | ザ・カウンシル・オヴ・ザ・クイーンズランド・インスティテュート・オヴ・メディカル・リサーチ | 免疫原性組成物及びその使用 |
| WO2023144665A1 (en) | 2022-01-28 | 2023-08-03 | Glaxosmithkline Biologicals Sa | Modified human cytomegalovirus proteins |
| CN115948468A (zh) * | 2022-09-09 | 2023-04-11 | 青岛大学 | 一种人巨细胞病毒重组载体及其制备方法和应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235877A (en) | 1979-06-27 | 1980-11-25 | Merck & Co., Inc. | Liposome particle containing viral or bacterial antigenic subunit |
| US4372945A (en) | 1979-11-13 | 1983-02-08 | Likhite Vilas V | Antigen compounds |
| IL61904A (en) | 1981-01-13 | 1985-07-31 | Yeda Res & Dev | Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same |
| US4436727A (en) | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
| US4866034A (en) | 1982-05-26 | 1989-09-12 | Ribi Immunochem Research Inc. | Refined detoxified endotoxin |
| US6100064A (en) * | 1984-04-06 | 2000-08-08 | Chiron Corporation | Secreted viral proteins useful for vaccines and diagnostics |
| US4877611A (en) | 1986-04-15 | 1989-10-31 | Ribi Immunochem Research Inc. | Vaccine containing tumor antigens and adjuvants |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| CA1331443C (en) | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| DE69015222T2 (de) | 1989-02-04 | 1995-05-04 | Akzo Nv | Tocole als Impfstoffadjuvans. |
| ES2162139T5 (es) | 1993-03-23 | 2008-05-16 | Smithkline Beecham Biologicals S.A. | Composiciones de vacuna que contienen monofosforil-lipido a 3-o-desacilado. |
| CN1055093C (zh) | 1993-11-17 | 2000-08-02 | 实验室奥姆公司 | 葡糖胺二糖类、其制备方法和用途、以及含有这些二糖的药物组合物 |
| GB9409962D0 (en) | 1994-05-18 | 1994-07-06 | Smithkline Beecham Biolog | Novel compounds |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| SK18602000A3 (sk) | 1998-06-08 | 2001-07-10 | Sca Emballage France | Obal umožňujúci rýchle vyrovnanie |
| CZ302062B6 (cs) | 1998-06-30 | 2010-09-22 | Om Pharma | Derivát acyldipeptidu, zpusob jeho prípravy, meziprodukty pro jeho prípravu a farmaceutický prostredek, který ho obsahuje |
| DE19910044A1 (de) * | 1999-03-08 | 2000-09-14 | Bodo Plachter | Virale Partikel, die nach Infektion durch humanes Cytomegalovirus freigesetzt werden und ihre Verwendung als Impfstoff |
| AU1581400A (en) | 1999-12-22 | 2001-07-03 | Om Pharma | Acyl pseudopeptides bearing a functionalised auxiliary spacer |
| ATE549031T1 (de) * | 2007-09-21 | 2012-03-15 | Sanofi Pasteur | Impfstoffzusammensetzung zur prävention von cmv- infektionen |
| WO2010089129A1 (en) * | 2009-02-06 | 2010-08-12 | Cormus Srl | Inhibitors of viral fusion and uses thereof |
| WO2011053798A2 (en) * | 2009-10-30 | 2011-05-05 | The Administrators Of The Tulane Educational Fund | Peptide compositions and methods for inhibiting herpesvirus infection |
| US20130196903A1 (en) * | 2010-08-11 | 2013-08-01 | Jv Bio Srl | Multimeric Inhibitors of Viral Fusion and Uses Thereof |
-
2011
- 2011-10-14 AR ARP110103818 patent/AR083454A1/es unknown
- 2011-10-14 KR KR20137012553A patent/KR20130140009A/ko not_active Withdrawn
- 2011-10-14 MX MX2013004149A patent/MX2013004149A/es not_active Application Discontinuation
- 2011-10-14 US US13/879,438 patent/US20130216613A1/en not_active Abandoned
- 2011-10-14 CA CA2813522A patent/CA2813522C/en active Active
- 2011-10-14 SG SG2013023791A patent/SG189176A1/en unknown
- 2011-10-14 CN CN201180060437.9A patent/CN103237560B/zh active Active
- 2011-10-14 AU AU2011315447A patent/AU2011315447A1/en not_active Abandoned
- 2011-10-14 EP EP11768058.7A patent/EP2627352B1/en active Active
- 2011-10-14 WO PCT/EP2011/068040 patent/WO2012049317A2/en not_active Ceased
- 2011-10-14 JP JP2013533239A patent/JP6138047B2/ja active Active
- 2011-10-14 PH PH1/2013/500724A patent/PH12013500724A1/en unknown
- 2011-10-14 ES ES11768058.7T patent/ES2635014T3/es active Active
- 2011-10-14 MA MA35897A patent/MA34802B1/fr unknown
- 2011-10-14 TW TW100137497A patent/TW201305190A/zh unknown
- 2011-10-14 BR BR112013008624-6A patent/BR112013008624B1/pt active IP Right Grant
-
2013
- 2013-04-10 IL IL225667A patent/IL225667A0/en unknown
- 2013-04-12 DO DO2013000080A patent/DOP2013000080A/es unknown
- 2013-04-15 CL CL2013001037A patent/CL2013001037A1/es unknown
- 2013-04-25 CO CO13105813A patent/CO6741153A2/es not_active Application Discontinuation
- 2013-05-02 CR CR20130191A patent/CR20130191A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20130140009A (ko) | 2013-12-23 |
| EP2627352A2 (en) | 2013-08-21 |
| EP2627352B1 (en) | 2017-05-10 |
| PH12013500724A1 (en) | 2017-08-23 |
| CA2813522C (en) | 2022-06-21 |
| MA34802B1 (fr) | 2014-01-02 |
| CA2813522A1 (en) | 2012-04-19 |
| CO6741153A2 (es) | 2013-08-30 |
| AU2011315447A1 (en) | 2013-05-09 |
| US20130216613A1 (en) | 2013-08-22 |
| WO2012049317A2 (en) | 2012-04-19 |
| MX2013004149A (es) | 2013-09-02 |
| IL225667A0 (en) | 2013-06-27 |
| BR112013008624B1 (pt) | 2022-07-26 |
| BR112013008624A2 (pt) | 2021-05-11 |
| JP6138047B2 (ja) | 2017-05-31 |
| AR083454A1 (es) | 2013-02-27 |
| CN103237560B (zh) | 2016-05-11 |
| SG189176A1 (en) | 2013-05-31 |
| DOP2013000080A (es) | 2013-08-15 |
| WO2012049317A3 (en) | 2012-06-21 |
| ES2635014T3 (es) | 2017-10-02 |
| TW201305190A (zh) | 2013-02-01 |
| CN103237560A (zh) | 2013-08-07 |
| JP2013544074A (ja) | 2013-12-12 |
| CR20130191A (es) | 2013-06-28 |
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