CL2011001225A1 - Formulacion farmaceutica en solucion acuosa que comprende desde 1% hasta 5% (p/v) de una sal de diclofenaco, desde 3% hasta 30% (p/v) de al menos un polioxialquilen ester de hidroxido de acido graso y un co-solvente seleccionado de etanol, propanol, glicerol, propilenglicol entre otros. - Google Patents
Formulacion farmaceutica en solucion acuosa que comprende desde 1% hasta 5% (p/v) de una sal de diclofenaco, desde 3% hasta 30% (p/v) de al menos un polioxialquilen ester de hidroxido de acido graso y un co-solvente seleccionado de etanol, propanol, glicerol, propilenglicol entre otros.Info
- Publication number
- CL2011001225A1 CL2011001225A1 CL2011001225A CL2011001225A CL2011001225A1 CL 2011001225 A1 CL2011001225 A1 CL 2011001225A1 CL 2011001225 A CL2011001225 A CL 2011001225A CL 2011001225 A CL2011001225 A CL 2011001225A CL 2011001225 A1 CL2011001225 A1 CL 2011001225A1
- Authority
- CL
- Chile
- Prior art keywords
- propanol
- glycerol
- ethanol
- aqueous solution
- fatty acid
- Prior art date
Links
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 title abstract 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 title abstract 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title abstract 4
- 239000007864 aqueous solution Substances 0.000 title abstract 2
- 239000006184 cosolvent Substances 0.000 title abstract 2
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical class OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 title abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 title abstract 2
- 150000002148 esters Chemical class 0.000 title abstract 2
- 229930195729 fatty acid Natural products 0.000 title abstract 2
- 239000000194 fatty acid Substances 0.000 title abstract 2
- -1 fatty acid hydroxide Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 title abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Formulación farmacéutica en solución acuosa que comprende desde 1% hasta 5% (p/v) de una sal de diclofenaco, desde 3% hasta 30% (p/v) de al menos un polioxialquilen ester de hidróxido de ácido graso y un co-solvente seleccionado de etanol, propanol, glicerol, propilen glicol entre otros.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08170177 | 2008-11-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2011001225A1 true CL2011001225A1 (es) | 2011-11-11 |
Family
ID=40512558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2011001225A CL2011001225A1 (es) | 2008-11-28 | 2011-05-26 | Formulacion farmaceutica en solucion acuosa que comprende desde 1% hasta 5% (p/v) de una sal de diclofenaco, desde 3% hasta 30% (p/v) de al menos un polioxialquilen ester de hidroxido de acido graso y un co-solvente seleccionado de etanol, propanol, glicerol, propilenglicol entre otros. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20110275717A1 (es) |
| EP (1) | EP2364140A1 (es) |
| JP (1) | JP2012510439A (es) |
| KR (1) | KR20110091862A (es) |
| CN (1) | CN102227211A (es) |
| AU (1) | AU2009319167A1 (es) |
| BR (1) | BRPI0921654A2 (es) |
| CA (1) | CA2742645A1 (es) |
| CL (1) | CL2011001225A1 (es) |
| EA (1) | EA201100863A1 (es) |
| IL (1) | IL212602A0 (es) |
| MX (1) | MX2011005410A (es) |
| NZ (1) | NZ592647A (es) |
| WO (1) | WO2010060798A1 (es) |
| ZA (1) | ZA201103335B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA200903135B (en) | 2006-10-17 | 2010-08-25 | Nuvo Res Inc | Diclofenac gel |
| US8546450B1 (en) | 2009-03-31 | 2013-10-01 | Nuvo Research Inc. | Treatment of pain with topical diclofenac compounds |
| US8618164B2 (en) | 2009-03-31 | 2013-12-31 | Nuvo Research Inc. | Treatment of pain with topical diclofenac compounds |
| ITMI20121205A1 (it) | 2012-07-11 | 2014-01-12 | Glycores 2000 Srl | Composizione con attivita' antinfiammatoria ed analgesica da somministrare per uso esterno mediante vaporizzazione |
| EP2872177B1 (en) * | 2012-07-12 | 2017-12-20 | Ferring BV | Diclofenac formulations |
| US20140187635A1 (en) | 2012-12-28 | 2014-07-03 | Themis Medicare Limited | Diclofenac compositions |
| CN104274436B (zh) * | 2013-07-03 | 2017-05-10 | 成都力思特制药股份有限公司 | 双氯芬酸钠盐酸利多卡因复方药物注射液及其制备方法 |
| KR101524473B1 (ko) * | 2014-12-22 | 2015-06-02 | 주식회사 한국팜비오 | 주사제 조성물 |
| KR101654900B1 (ko) * | 2016-02-04 | 2016-09-07 | 주식회사 한국루베 | 저독성 화생방 제독제 |
| US20220280463A1 (en) | 2019-09-09 | 2022-09-08 | Ftf Pharma Private Limited | Pharmaceutical formulations comprising diclofenac |
| WO2021228804A1 (de) * | 2020-05-12 | 2021-11-18 | U. Windmöller Innovation Gmbh & Co. Kg | Verfahren zur herstellung von hydroxyfettsäurebasierten polyolen |
| CN112516081B (zh) * | 2020-12-16 | 2023-03-10 | 郑州百瑞动物药业有限公司 | 一种双氯芬酸注射液及其制备方法 |
| EP4112042A1 (en) * | 2021-06-30 | 2023-01-04 | GSK Consumer Healthcare SARL | Nanoemulsion comprising diclofenac |
| KR20240164788A (ko) | 2022-03-25 | 2024-11-20 | 글리코레스 2000 에세.에레.엘레 | 항염증 및 진통 활성을 갖는 국소 약학적 조성물 및 이의 용도 |
| US20250099369A1 (en) | 2023-09-27 | 2025-03-27 | Andros Pharmaceuticals Co., Ltd. | Topical delivery compositions comprising non-steroidal anti-inflammatory drugs |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH655656B (es) * | 1982-10-07 | 1986-05-15 | ||
| ES2053161T3 (es) * | 1989-09-21 | 1994-07-16 | Ciba Vision Ag | Composiciones antimicrobianas. |
| JP4275751B2 (ja) * | 1996-12-27 | 2009-06-10 | 久光製薬株式会社 | 外用組成物 |
| ES2174462T3 (es) * | 1997-07-29 | 2002-11-01 | Upjohn Co | Formulacion autoestimulante para compuestos lipofilos. |
| GB2355656B (en) * | 1999-08-17 | 2004-04-07 | Galena As | Pharmaceutical compositions for oral and topical administration |
| EP1812033A4 (en) * | 2004-10-06 | 2009-11-11 | Tiltan Pharma Ltd | METHOD AND COMPOSITION FOR REINFORCE ANTI-ANGIOGENESIS THERAPY |
| AU2007270686B2 (en) * | 2006-07-07 | 2011-05-26 | Tiltan Pharma Ltd. | Anti-cancer therapy comprising an H2-blocker, at least one antiinflammatory agent and a cytotoxic agent |
| DE102007014947B4 (de) * | 2007-03-23 | 2010-05-27 | Axxonis Pharma Ag | Stabilisierte wässrige Lösungen von Ergolinverbindungen |
-
2009
- 2009-11-11 EP EP09748800A patent/EP2364140A1/en not_active Withdrawn
- 2009-11-11 CN CN2009801474197A patent/CN102227211A/zh active Pending
- 2009-11-11 MX MX2011005410A patent/MX2011005410A/es not_active Application Discontinuation
- 2009-11-11 BR BRPI0921654A patent/BRPI0921654A2/pt not_active IP Right Cessation
- 2009-11-11 US US13/128,747 patent/US20110275717A1/en not_active Abandoned
- 2009-11-11 WO PCT/EP2009/064971 patent/WO2010060798A1/en not_active Ceased
- 2009-11-11 KR KR1020117012471A patent/KR20110091862A/ko not_active Withdrawn
- 2009-11-11 CA CA2742645A patent/CA2742645A1/en not_active Abandoned
- 2009-11-11 NZ NZ592647A patent/NZ592647A/xx not_active IP Right Cessation
- 2009-11-11 EA EA201100863A patent/EA201100863A1/ru unknown
- 2009-11-11 JP JP2011537921A patent/JP2012510439A/ja active Pending
- 2009-11-11 AU AU2009319167A patent/AU2009319167A1/en not_active Abandoned
-
2011
- 2011-05-01 IL IL212602A patent/IL212602A0/en unknown
- 2011-05-06 ZA ZA2011/03335A patent/ZA201103335B/en unknown
- 2011-05-26 CL CL2011001225A patent/CL2011001225A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012510439A (ja) | 2012-05-10 |
| NZ592647A (en) | 2013-05-31 |
| US20110275717A1 (en) | 2011-11-10 |
| ZA201103335B (en) | 2012-01-25 |
| IL212602A0 (en) | 2011-07-31 |
| WO2010060798A1 (en) | 2010-06-03 |
| KR20110091862A (ko) | 2011-08-16 |
| EP2364140A1 (en) | 2011-09-14 |
| EA201100863A1 (ru) | 2011-12-30 |
| CN102227211A (zh) | 2011-10-26 |
| CA2742645A1 (en) | 2010-06-03 |
| BRPI0921654A2 (pt) | 2016-02-10 |
| MX2011005410A (es) | 2011-06-16 |
| AU2009319167A1 (en) | 2010-06-03 |
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