CL2009001956A1 - Composicion nutracéutica que comprende extracto de shilajit (250-500 mg), acido folico (200-500 ug), vitamina b6(20-40 ug), vitamina b12 (4-8 ug) y excipientes aceptables; metodo de fabricacion; y su uso para prevenir o tratar la enfermedad de alzheimer. - Google Patents
Composicion nutracéutica que comprende extracto de shilajit (250-500 mg), acido folico (200-500 ug), vitamina b6(20-40 ug), vitamina b12 (4-8 ug) y excipientes aceptables; metodo de fabricacion; y su uso para prevenir o tratar la enfermedad de alzheimer.Info
- Publication number
- CL2009001956A1 CL2009001956A1 CL2009001956A CL2009001956A CL2009001956A1 CL 2009001956 A1 CL2009001956 A1 CL 2009001956A1 CL 2009001956 A CL2009001956 A CL 2009001956A CL 2009001956 A CL2009001956 A CL 2009001956A CL 2009001956 A1 CL2009001956 A1 CL 2009001956A1
- Authority
- CL
- Chile
- Prior art keywords
- vitamin
- composition
- folic acid
- disease
- manufacturing
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 7
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 title abstract 4
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000304 folic acid Drugs 0.000 title abstract 2
- 235000019152 folic acid Nutrition 0.000 title abstract 2
- 239000011724 folic acid Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 title abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 title 1
- 239000002417 nutraceutical Substances 0.000 title 1
- 235000021436 nutraceutical agent Nutrition 0.000 title 1
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 title 1
- RMRCNWBMXRMIRW-WYVZQNDMSA-L vitamin b12 Chemical compound N([C@@H]([C@@]1(C)[C@@](C)(CC(N)=O)[C@H](CCC(N)=O)\C(N1[Co+]C#N)=C(/C)\C1=N\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NCC(C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO RMRCNWBMXRMIRW-WYVZQNDMSA-L 0.000 title 1
- 229940011671 vitamin b6 Drugs 0.000 title 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000002778 food additive Substances 0.000 abstract 1
- 235000013373 food additive Nutrition 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4415—Pyridoxine, i.e. Vitamin B6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Mycology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UNA COMPOSICIÓN NUTRACÉUTICA PODEROSA ANTIOXIDANTE Y NEUROPROTECTORA QUE CONSISTE EN LA MEZCLA DE EXTRACTO DE SHILAJIT ANDINO (250 A 500 MG) Y ÁCIDO FÓLICO (200 A 500 UG), JUNTO A PEQUEÑAS CANTIDADES DE VITAMINAS B6 (20 A 40 UG) Y B12 (4 A 8 UG) CON SUMIDAS POR DÍA. SE DIVULGA ADEMÁS EL MÉTODO DE FABRICACIÓN DE LA COMPOSICIÓN POR MEZCLA ALEATORIA DE SUS COMPONENTES.<br /> ESTA COMPOSICIÓN, SE ENCUENTRA EN FORMA DE LIOFILIZADO, CÁPSULAS, COMPRIMIDOS O GRAGEAS Y ES ÚTIL PARA LA PREVENCIÓN Y TRATAMIENTO DE LA ENFERMEDAD DE ALZHEIMER.<br /> LA COMPOSICIÓN ES APROPIADA PARA EL CONSUMO HUMANO DE MANERA DIRECTA POR VÍA ORAL, YA SEA EN FORMA SÓLIDA COMO POLVO O EN SUSPENSIÓN DEL EXTRACTO, COMO ADITIVO EN ALIMENTOS O COMO AGENTE NUTRACÉUTICO. PUEDE SER FORMULADA COMO UN AGENTE NUTRACÉUTICO INGREDIENTE DE BEBIDAS O COMO MEDICAMENTO JUNTO A EXCIPIENTES AUTORIZADOS.<br />
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CL2009001956A CL2009001956A1 (es) | 2009-10-09 | 2009-10-09 | Composicion nutracéutica que comprende extracto de shilajit (250-500 mg), acido folico (200-500 ug), vitamina b6(20-40 ug), vitamina b12 (4-8 ug) y excipientes aceptables; metodo de fabricacion; y su uso para prevenir o tratar la enfermedad de alzheimer. |
| CA2776919A CA2776919C (en) | 2009-10-09 | 2010-10-08 | Nutraceutical composition that comprises extract of shilajit, folic acid, vitamin b12 and vitamin b6 and the use thereof for preventing and/or treating neurodegenerative diseases and/or the cognitive deterioration associated with cerebral ageing |
| GB1207939.8A GB2487871B (en) | 2009-10-09 | 2010-10-08 | Nutraceutical composition comprising extract of Andean shilajit, folic acid, vitamin B12 and vitamin B6 |
| PCT/CL2010/000043 WO2011041920A2 (es) | 2009-10-09 | 2010-10-08 | Composición nutracéutica que comprende extracto de shilajit, ácido fólico, vitamina b12 y vitamina b6 y su uso para prevenir y/o tratar enfermedades neurodegenerativas y/o el deterioro cognitivo asociado al envejecimiento cerebral |
| US13/496,140 US8784804B2 (en) | 2009-10-09 | 2010-10-08 | Nutraceutical composition that comprises extract of andean shilajit, for preventing and/or treating neurodegenerative diseases and/or the cognitive deterioration associated with cerebral aging |
| AU2010305251A AU2010305251B2 (en) | 2009-10-09 | 2010-10-08 | Nutraceutical composition that comprises extract of shilajit, folic acid, vitamin B12 and Vitamin B6 and the use thereof for preventing and/or treating neurodegenerative diseases and/or the cognitive deterioration associated with cerebral ageing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CL2009001956A CL2009001956A1 (es) | 2009-10-09 | 2009-10-09 | Composicion nutracéutica que comprende extracto de shilajit (250-500 mg), acido folico (200-500 ug), vitamina b6(20-40 ug), vitamina b12 (4-8 ug) y excipientes aceptables; metodo de fabricacion; y su uso para prevenir o tratar la enfermedad de alzheimer. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2009001956A1 true CL2009001956A1 (es) | 2010-06-04 |
Family
ID=43857199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2009001956A CL2009001956A1 (es) | 2009-10-09 | 2009-10-09 | Composicion nutracéutica que comprende extracto de shilajit (250-500 mg), acido folico (200-500 ug), vitamina b6(20-40 ug), vitamina b12 (4-8 ug) y excipientes aceptables; metodo de fabricacion; y su uso para prevenir o tratar la enfermedad de alzheimer. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8784804B2 (es) |
| AU (1) | AU2010305251B2 (es) |
| CA (1) | CA2776919C (es) |
| CL (1) | CL2009001956A1 (es) |
| GB (1) | GB2487871B (es) |
| WO (1) | WO2011041920A2 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015107375A1 (es) | 2013-12-20 | 2015-07-23 | Vergara Campillo Ramiro Moises | Combinación de piridoxina, ácido fólico y iones de magnesio para el tratamiento del cáncer |
| US20170295834A1 (en) * | 2015-11-25 | 2017-10-19 | Alexander LaCroix | All-Natural Bitterness-Reducing Flavor System |
| KR20240132587A (ko) * | 2023-02-27 | 2024-09-04 | 의료법인 명지의료재단 | 실라짓을 포함하는 알츠하이머성 치매 예방 및 치료용 조성물 |
| CN118453638A (zh) * | 2024-05-22 | 2024-08-09 | 中国人民解放军军事科学院军事医学研究院 | 一种营养组合物及其在线粒体功能损伤修复中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5405613A (en) * | 1991-12-11 | 1995-04-11 | Creative Nutrition Canada Corp. | Vitamin/mineral composition |
| US6440436B1 (en) * | 2001-05-18 | 2002-08-27 | Natreon Inc. | Process for preparing purified shilajit composition from native shilajit |
| US6558712B1 (en) * | 2001-09-21 | 2003-05-06 | Natreon Inc. | Delivery system for pharmaceutical, nutritional and cosmetic ingredients |
| US20050085454A1 (en) * | 2003-10-16 | 2005-04-21 | Natreon Inc. | Phenolic antioxidant-chromium complexes for treatment or prevention of type 2 diabetes or glucose intolerance |
| US7250181B2 (en) * | 2005-01-19 | 2007-07-31 | Natreon, Inc. | Polyherbal compositions and methods for treating viral infections |
-
2009
- 2009-10-09 CL CL2009001956A patent/CL2009001956A1/es unknown
-
2010
- 2010-10-08 US US13/496,140 patent/US8784804B2/en active Active
- 2010-10-08 WO PCT/CL2010/000043 patent/WO2011041920A2/es not_active Ceased
- 2010-10-08 AU AU2010305251A patent/AU2010305251B2/en active Active
- 2010-10-08 GB GB1207939.8A patent/GB2487871B/en not_active Expired - Fee Related
- 2010-10-08 CA CA2776919A patent/CA2776919C/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011041920A2 (es) | 2011-04-14 |
| AU2010305251A1 (en) | 2012-05-31 |
| US8784804B2 (en) | 2014-07-22 |
| GB201207939D0 (en) | 2012-06-20 |
| WO2011041920A3 (es) | 2011-06-03 |
| CA2776919C (en) | 2015-07-14 |
| US20120269794A1 (en) | 2012-10-25 |
| WO2011041920A8 (es) | 2012-04-12 |
| CA2776919A1 (en) | 2011-04-14 |
| AU2010305251B2 (en) | 2013-12-19 |
| GB2487871A (en) | 2012-08-08 |
| GB2487871B (en) | 2017-04-05 |
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