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CL2009001379A1 - Composicion acuosa farmaceutica que comprende moxifloxacino y un vehiculo que incluye cloruro de sodio, un surfactante que es un alcohol polieter y un agente polisacarido potenciador de la viscosidad que comprende goma xantan; util como composición oftalmica. - Google Patents

Composicion acuosa farmaceutica que comprende moxifloxacino y un vehiculo que incluye cloruro de sodio, un surfactante que es un alcohol polieter y un agente polisacarido potenciador de la viscosidad que comprende goma xantan; util como composición oftalmica.

Info

Publication number
CL2009001379A1
CL2009001379A1 CL2009001379A CL2009001379A CL2009001379A1 CL 2009001379 A1 CL2009001379 A1 CL 2009001379A1 CL 2009001379 A CL2009001379 A CL 2009001379A CL 2009001379 A CL2009001379 A CL 2009001379A CL 2009001379 A1 CL2009001379 A1 CL 2009001379A1
Authority
CL
Chile
Prior art keywords
surfactant
sodium chloride
moxifloxacin
useful
aqueous pharmaceutical
Prior art date
Application number
CL2009001379A
Other languages
English (en)
Inventor
Martinez
Bernardas Maria Inmaculada Campins
Ridruejo Nuria Jimenez
Abad Roman Vidal
Perdiguer Nuria Carreras
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40857591&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2009001379(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of CL2009001379A1 publication Critical patent/CL2009001379A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Composición acuosa farmacéutica que comprende un antibiótico derivado de fluoroquinolona y un vehículo que comprende cloruro de sodio, surfactante, sistema antimicrobiano de complejo borato/poliol y un agente polisacárido potenciador de la viscosidad.
CL2009001379A 2008-06-09 2009-06-08 Composicion acuosa farmaceutica que comprende moxifloxacino y un vehiculo que incluye cloruro de sodio, un surfactante que es un alcohol polieter y un agente polisacarido potenciador de la viscosidad que comprende goma xantan; util como composición oftalmica. CL2009001379A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5987708P 2008-06-09 2008-06-09

Publications (1)

Publication Number Publication Date
CL2009001379A1 true CL2009001379A1 (es) 2010-09-10

Family

ID=40857591

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2009001379A CL2009001379A1 (es) 2008-06-09 2009-06-08 Composicion acuosa farmaceutica que comprende moxifloxacino y un vehiculo que incluye cloruro de sodio, un surfactante que es un alcohol polieter y un agente polisacarido potenciador de la viscosidad que comprende goma xantan; util como composición oftalmica.

Country Status (16)

Country Link
US (2) US8450311B2 (es)
EP (1) EP2299974A1 (es)
JP (1) JP5509201B2 (es)
KR (1) KR101587056B1 (es)
CN (3) CN104814961A (es)
AR (1) AR072071A1 (es)
AU (1) AU2009257778B2 (es)
BR (1) BRPI0914971A2 (es)
CA (1) CA2726616A1 (es)
CL (1) CL2009001379A1 (es)
MX (1) MX2010012933A (es)
RU (1) RU2494727C2 (es)
TW (2) TWI544934B (es)
UY (1) UY31880A (es)
WO (1) WO2009151974A1 (es)
ZA (1) ZA201008543B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
TWI544934B (zh) 2008-06-09 2016-08-11 愛爾康研究有限公司 含有氟喹諾酮抗生素藥物之經改良藥學組成物
CN103181892A (zh) * 2013-02-20 2013-07-03 南京恒道医药科技有限公司 盐酸莫西沙星滴眼液及其制备方法
CN105687127B (zh) * 2016-01-29 2018-09-28 上海利康瑞生物工程有限公司 关节腔用盐酸莫西沙星几丁糖注射液及其制备方法
CN110354074A (zh) * 2019-08-16 2019-10-22 合肥华威药业有限公司 一种缓释型盐酸莫西沙星眼用制剂及其制备方法
CN113797164B (zh) * 2020-06-17 2023-07-14 成都瑞沐生物医药科技有限公司 一种眼用制剂的载体或辅料及其制备方法和应用
US11484538B2 (en) 2020-08-26 2022-11-01 Somerset Therapeutics, Llc Bromfenac, prednisolone, and moxifloxacin compositions and methods
US11523987B2 (en) 2020-08-26 2022-12-13 Somerset Therapeutics, Llc Trimcinolone and moxifloxacin methods
US12102632B2 (en) 2020-08-26 2024-10-01 Somerset Therapeutics, Llc Quinolone dispersions
US11382910B2 (en) 2020-08-26 2022-07-12 Somerset Therapeutics, Llc. Loteprednol and moxifloxacin compositions and methods

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136177A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
US5505953A (en) * 1992-05-06 1996-04-09 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
DK0639070T4 (da) 1992-05-06 2010-12-13 Alcon Lab Inc Anvendelse af borat-polyolkomplekser til ophtalmiske præparater
AU718199B2 (en) 1996-12-13 2000-04-06 Alcon Laboratories, Inc. Use of low molecular weight amino alcohols in ophthalmic compositions
RU2130189C1 (ru) 1997-02-20 1999-05-10 Александр Сергеевич Парфенов Способ определения тканевого холестерина кожи
US6261547B1 (en) * 1998-04-07 2001-07-17 Alcon Manufacturing, Ltd. Gelling ophthalmic compositions containing xanthan gum
US6174524B1 (en) * 1999-03-26 2001-01-16 Alcon Laboratories, Inc. Gelling ophthalmic compositions containing xanthan gum
KR100598722B1 (ko) 1998-04-07 2006-07-11 알콘 래보레이토리스, 인코퍼레이티드 잔탄 검을 포함하는 겔화 안과용 조성물
US6716830B2 (en) * 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
AR020661A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
US6166012A (en) * 1999-07-30 2000-12-26 Allergan Sales, Inc. Antibiotic compositions and method for using same
PL354928A1 (en) * 1999-11-01 2004-03-22 Alcon, Inc. Pharmaceutical compositions containing a fluoroquinolone antibiotic drug and xanthan gum
US20010049366A1 (en) * 2000-02-09 2001-12-06 Alcon Universal Ltd. Topical solution formulations containing an antibiotic and a corticosteroid
EP1305033B1 (en) * 2000-07-28 2004-10-20 Alcon, Inc Pharmaceutical compositions containing tobramycin and xanthan gum
WO2002049627A2 (en) 2000-12-20 2002-06-27 Alcon, Inc. Antifungal compositions containing an antibiotic and one or more amidoamines
US20060141059A1 (en) 2004-12-27 2006-06-29 Alcon, Inc. Self-preserved ophthalmic pharmaceutical compositions containing tobramycin
MX2009003877A (es) * 2006-10-12 2009-09-15 Senju Pharma Co Preparacion liquida acuosa que tiene una penetracion mejorada de gatifloxacina intraocular.
BRPI0719514A2 (pt) * 2006-10-12 2014-10-07 Kyorin Seiyaku Kk Preparações líquidas aquosas compreendendo gatifloxacina
US7795316B1 (en) * 2007-12-19 2010-09-14 Alcon Research, Ltd. Topical ophthalmic compositions containing tobramycin and dexamethasone
TWI544934B (zh) 2008-06-09 2016-08-11 愛爾康研究有限公司 含有氟喹諾酮抗生素藥物之經改良藥學組成物
EP2309980A1 (en) * 2008-07-08 2011-04-20 S.I.F.I. Societa' Industria Farmaceutica Italiana Ophthalmic compositions for treating pathologies of the posterior segment of the eye

Also Published As

Publication number Publication date
US20130137715A1 (en) 2013-05-30
AR072071A1 (es) 2010-08-04
CN104814961A (zh) 2015-08-05
ZA201008543B (en) 2012-02-29
WO2009151974A1 (en) 2009-12-17
RU2494727C2 (ru) 2013-10-10
RU2010154545A (ru) 2012-07-20
US9114168B2 (en) 2015-08-25
CN102056590A (zh) 2011-05-11
EP2299974A1 (en) 2011-03-30
UY31880A (es) 2009-11-10
TW201000102A (en) 2010-01-01
AU2009257778A1 (en) 2009-12-17
MX2010012933A (es) 2011-01-25
JP5509201B2 (ja) 2014-06-04
US8450311B2 (en) 2013-05-28
CA2726616A1 (en) 2009-12-17
CN103550141A (zh) 2014-02-05
TWI495469B (zh) 2015-08-11
KR101587056B1 (ko) 2016-01-21
TW201503909A (zh) 2015-02-01
BRPI0914971A2 (pt) 2017-06-20
JP2011522823A (ja) 2011-08-04
KR20110039219A (ko) 2011-04-15
TWI544934B (zh) 2016-08-11
AU2009257778B2 (en) 2014-09-11
US20090306128A1 (en) 2009-12-10

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