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CL2008003054A1 - Compuestos derivados de imidazolina-2,4-diona; procedimiento de preparacion; composicion farmaceutica y; su uso tratar, prevenir o retrasar el progreso de una condicion, enfermedad o desorden que puede ser modulado por repectores npy y2. - Google Patents

Compuestos derivados de imidazolina-2,4-diona; procedimiento de preparacion; composicion farmaceutica y; su uso tratar, prevenir o retrasar el progreso de una condicion, enfermedad o desorden que puede ser modulado por repectores npy y2.

Info

Publication number
CL2008003054A1
CL2008003054A1 CL2008003054A CL2008003054A CL2008003054A1 CL 2008003054 A1 CL2008003054 A1 CL 2008003054A1 CL 2008003054 A CL2008003054 A CL 2008003054A CL 2008003054 A CL2008003054 A CL 2008003054A CL 2008003054 A1 CL2008003054 A1 CL 2008003054A1
Authority
CL
Chile
Prior art keywords
npy
disorder
modulated
progress
disease
Prior art date
Application number
CL2008003054A
Other languages
English (en)
Inventor
Nozulak
Y Orain Joachim
David
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CL2008003054A1 publication Critical patent/CL2008003054A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/80—Two oxygen atoms, e.g. hydantoin with hetero atoms or acyl radicals directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Compuestos heterociclios derivados de imidazolina, procedimiento de preparación, composición farmacéutica, combinación farmacéutica, útiles para tratar, prevenir o retrasar el progreso de una condición, enfermedad o desorden que puede ser modulado por repectores NPY Y2.
CL2008003054A 2007-10-16 2008-10-16 Compuestos derivados de imidazolina-2,4-diona; procedimiento de preparacion; composicion farmaceutica y; su uso tratar, prevenir o retrasar el progreso de una condicion, enfermedad o desorden que puede ser modulado por repectores npy y2. CL2008003054A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07118602 2007-10-16

Publications (1)

Publication Number Publication Date
CL2008003054A1 true CL2008003054A1 (es) 2009-05-15

Family

ID=39111624

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008003054A CL2008003054A1 (es) 2007-10-16 2008-10-16 Compuestos derivados de imidazolina-2,4-diona; procedimiento de preparacion; composicion farmaceutica y; su uso tratar, prevenir o retrasar el progreso de una condicion, enfermedad o desorden que puede ser modulado por repectores npy y2.

Country Status (9)

Country Link
US (1) US20090099243A1 (es)
EP (1) EP2212314A1 (es)
JP (1) JP2011500632A (es)
CN (1) CN101827840A (es)
AR (1) AR068784A1 (es)
CL (1) CL2008003054A1 (es)
PE (1) PE20090967A1 (es)
TW (1) TW200927747A (es)
WO (1) WO2009050200A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101827826A (zh) * 2007-10-16 2010-09-08 诺瓦提斯公司 4-苯基-5-氧代-咪唑衍生物、其药物组合物及其应用
IN2012DN02580A (es) 2009-09-04 2015-08-28 Univ Vanderbilt
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
CN104000816B (zh) * 2014-05-28 2016-03-30 中山大学 二氧代咪唑烷-酰胺类化合物在制备抗hiv-1病毒药物中的应用
WO2022143771A1 (zh) * 2020-12-31 2022-07-07 上海医药集团股份有限公司 一类RORγt调节剂、其制备方法及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270317A (en) * 1990-03-20 1993-12-14 Elf Sanofi N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
EP0640594A1 (en) * 1993-08-23 1995-03-01 Fujirebio Inc. Hydantoin derivative as metalloprotease inhibitor
WO2005030754A1 (en) * 2003-09-24 2005-04-07 Janssen Pharmaceutica, N.V. Indole or quinoline derivatives as non-pepticid npy y2 receptor inhibitors useful for the treatment of anxiolytic and depressive disorders and obesity
WO2005090316A1 (en) * 2004-03-12 2005-09-29 Wyeth HYDANTOINS HAVING RNase MODULATORY ACTIVITY
DK1899325T3 (da) * 2005-06-23 2012-03-05 Janssen Pharmaceutica Nv Imidazolinon- og hydantoinderivater som hidtil ukendte hæmmere af histondeacetylase
TW200730523A (en) * 2005-07-29 2007-08-16 Wyeth Corp Cycloalkyl amino-hydantoin compounds and use thereof for β-secretase modulation
CN101827826A (zh) * 2007-10-16 2010-09-08 诺瓦提斯公司 4-苯基-5-氧代-咪唑衍生物、其药物组合物及其应用

Also Published As

Publication number Publication date
CN101827840A (zh) 2010-09-08
TW200927747A (en) 2009-07-01
JP2011500632A (ja) 2011-01-06
US20090099243A1 (en) 2009-04-16
AR068784A1 (es) 2009-12-02
PE20090967A1 (es) 2009-08-10
WO2009050200A1 (en) 2009-04-23
EP2212314A1 (en) 2010-08-04

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