[go: up one dir, main page]

CL2007001878A1 - Composition of biodegradable microspheres comprising a grafted or star-shaped copolymer, in block with segments of poly (n-vinyl-2-pyrrolidone) and biodegradable segments, and a biologically active agent; use of said composition; and method for the preparation of a microsphere composition. - Google Patents

Composition of biodegradable microspheres comprising a grafted or star-shaped copolymer, in block with segments of poly (n-vinyl-2-pyrrolidone) and biodegradable segments, and a biologically active agent; use of said composition; and method for the preparation of a microsphere composition.

Info

Publication number
CL2007001878A1
CL2007001878A1 CL2007001878A CL2007001878A CL2007001878A1 CL 2007001878 A1 CL2007001878 A1 CL 2007001878A1 CL 2007001878 A CL2007001878 A CL 2007001878A CL 2007001878 A CL2007001878 A CL 2007001878A CL 2007001878 A1 CL2007001878 A1 CL 2007001878A1
Authority
CL
Chile
Prior art keywords
composition
segments
biodegradable
grafted
pyrrolidone
Prior art date
Application number
CL2007001878A
Other languages
Spanish (es)
Inventor
Laibin Luo
Francois Ravenelle
David Lessard
Damon Smith
Original Assignee
Labopharm Inc
Labopharm Europe Ltd
Labopharm Barbados Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labopharm Inc, Labopharm Europe Ltd, Labopharm Barbados Ltd filed Critical Labopharm Inc
Publication of CL2007001878A1 publication Critical patent/CL2007001878A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

Composición de microesferas biodegradables que comprende un copolímero injertado o en forma de estrella, en bloque con segmentos de poli(n-vinil-2-pirrolidona) y segmentos biodegradables, y un agente biológicamente activo; uso de dicha composición; y método para la preparación de una composición de microesferas.Composition of biodegradable microspheres comprising a grafted or star-shaped copolymer, in block with poly (n-vinyl-2-pyrrolidone) segments and biodegradable segments, and a biologically active agent; use of said composition; and method for the preparation of a microsphere composition.

CL2007001878A 2005-12-27 2007-06-26 Composition of biodegradable microspheres comprising a grafted or star-shaped copolymer, in block with segments of poly (n-vinyl-2-pyrrolidone) and biodegradable segments, and a biologically active agent; use of said composition; and method for the preparation of a microsphere composition. CL2007001878A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75339405P 2005-12-27 2005-12-27
PCT/CA2006/002078 WO2007073596A1 (en) 2005-12-27 2006-12-21 Degradable polymeric microsphere composition

Publications (1)

Publication Number Publication Date
CL2007001878A1 true CL2007001878A1 (en) 2008-01-18

Family

ID=38217646

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2007001878A CL2007001878A1 (en) 2005-12-27 2007-06-26 Composition of biodegradable microspheres comprising a grafted or star-shaped copolymer, in block with segments of poly (n-vinyl-2-pyrrolidone) and biodegradable segments, and a biologically active agent; use of said composition; and method for the preparation of a microsphere composition.

Country Status (4)

Country Link
AR (1) AR061655A1 (en)
CA (1) CA2634830A1 (en)
CL (1) CL2007001878A1 (en)
WO (1) WO2007073596A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060198891A1 (en) 2004-11-29 2006-09-07 Francois Ravenelle Solid formulations of liquid biologically active agents
US8580307B2 (en) * 2006-06-22 2013-11-12 Ethicon, Inc. High glass transition temperature absorbable microspheres
US9714318B2 (en) * 2013-07-26 2017-07-25 Stratasys, Inc. Polyglycolic acid support material for additive manufacturing systems
CN104072698A (en) * 2014-07-08 2014-10-01 成都市绿科华通科技有限公司 Drug-carrying block macromolecular material with star-shaped and porous structure
WO2016197262A1 (en) * 2015-06-12 2016-12-15 Bayer Pharma Aktiengesellschaft Process for the preparation of porous microparticles
CN114917411A (en) * 2022-05-31 2022-08-19 常州药物研究所有限公司 Mixed gel containing amphiphilic microspheres and preparation method thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0758244B2 (en) * 1994-05-06 2008-02-13 Pfizer Inc. Controlled-release dosage forms of azithromycin
CA2248592A1 (en) * 1998-08-31 2000-02-29 Christopher D. Batich Microspheres for use in the treatment of cancer
US6338859B1 (en) * 2000-06-29 2002-01-15 Labopharm Inc. Polymeric micelle compositions
US6579519B2 (en) * 2000-09-18 2003-06-17 Registrar, University Of Delhi Sustained release and long residing ophthalmic formulation and the process of preparing the same
US20030152622A1 (en) * 2001-10-25 2003-08-14 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral diuretic
AU2003231134A1 (en) * 2002-04-26 2003-11-10 Teva Pharmaceutical Industries, Ltd. Microparticle pharmaceutical compositions for intratumoral delivery
US20060198891A1 (en) * 2004-11-29 2006-09-07 Francois Ravenelle Solid formulations of liquid biologically active agents

Also Published As

Publication number Publication date
CA2634830A1 (en) 2007-07-05
WO2007073596A1 (en) 2007-07-05
AR061655A1 (en) 2008-09-10

Similar Documents

Publication Publication Date Title
WO2006009987A3 (en) Dissolvable film composition
CL2007001878A1 (en) Composition of biodegradable microspheres comprising a grafted or star-shaped copolymer, in block with segments of poly (n-vinyl-2-pyrrolidone) and biodegradable segments, and a biologically active agent; use of said composition; and method for the preparation of a microsphere composition.
EP1699397A4 (en) Tissue dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chistosan
TW200503791A (en) Absorbent polymer compositions, medical articles, and methods
WO2005018697A3 (en) Active agent delivery systems, including a single layer of a miscible polymer blend, medical devices, and methods
WO2006068972A3 (en) Tissue engineering devices for the repair and regeneration of tissue
WO2004099068A3 (en) Nanofiber surfaces for use in enhanced surface area applications
AU2003258209A1 (en) Active agent delivery systems, medical devices, and methods
EP1932301A4 (en) SYSTEMS, METHODS, SOFTWARE AND DEVICES BASED ON THE USE OF MESSAGING
WO2006069236A3 (en) Sustained release tooth whitening formulations and systems
WO2005044224A3 (en) Drug delivery system based on polymer nanoshells
PT1313453E (en) PARTICULATE VECTORS INTENDED TO IMPROVE ORAL ABSORPTION OF ACTIVE PRINCIPLES
BRPI0411752A (en) subcutaneous implants presenting limited initial release of the active principle and subsequent linearly variable
EP1928930A4 (en) Polyalkylene glycol monomer, polyalkylene glycol polymer containing the same, and application thereof
WO2006137934A3 (en) Purposeful movement of human migratory cells away from an agent source
BR0110043B1 (en) reversible gelling agent, use thereof, gel, foodstuff, and processes for forming a gel and for breaking a gel.
WO2006121908A3 (en) Impregnated polymer compositions and devices using them
TW200641025A (en) Reverse phase hydrophilic polymers and their use in water-expandandable elastomeric compositions
BRPI0611065A2 (en) defoaming agent and cement composition.
WO2008015653A3 (en) Polymeric viscosity modifiers
DE60233891D1 (en) SELECTIVE TARGETING OF APOPTOTIC CELLS
DE60139195D1 (en) ACTIVE POLYMERIC COMPOSITION, AND OBJECTS THAT USE THEM
AU2001235783A1 (en) Therapeutic compositions for pulmonary delivery
DK1742952T3 (en) (Poly) -aminoacetamide derivatives of epipodophyllotoxin, method of preparation thereof and uses thereof in therapeutics as anticancer agents
MX2009005947A (en) Microemulsion dosage forms of valsartan and methods of making the same.