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CL2007000916A1 - Uso de alcaftadina y de acido 6,11-dihidro-11-(1-metil-4-piperidiniliden)-5h-imidazo[2,1-b][3]benzazepin-3-carboxilico, sales, n-oxidos, solvatos e hidratos para tratar sintomas de alergia ocular, inflamacion ocular y sintomas nasales de alergia ocular; composiciones oftalmicas que los comprenden; su uso y kit farmaceutico. - Google Patents

Uso de alcaftadina y de acido 6,11-dihidro-11-(1-metil-4-piperidiniliden)-5h-imidazo[2,1-b][3]benzazepin-3-carboxilico, sales, n-oxidos, solvatos e hidratos para tratar sintomas de alergia ocular, inflamacion ocular y sintomas nasales de alergia ocular; composiciones oftalmicas que los comprenden; su uso y kit farmaceutico.

Info

Publication number
CL2007000916A1
CL2007000916A1 CL2007000916A CL2007000916A CL2007000916A1 CL 2007000916 A1 CL2007000916 A1 CL 2007000916A1 CL 2007000916 A CL2007000916 A CL 2007000916A CL 2007000916 A CL2007000916 A CL 2007000916A CL 2007000916 A1 CL2007000916 A1 CL 2007000916A1
Authority
CL
Chile
Prior art keywords
eye
allergy
symptoms
alcaftadine
piperidinyliden
Prior art date
Application number
CL2007000916A
Other languages
English (en)
Inventor
Frans Janssens
Jagdish Parasrampuria
Avner Ingerman
Anton Megens
Original Assignee
Vistakon Pharmaceutical Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38468943&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2007000916(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vistakon Pharmaceutical Llc filed Critical Vistakon Pharmaceutical Llc
Publication of CL2007000916A1 publication Critical patent/CL2007000916A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Composición farmacéutica oftálmica que comprende alcaftadina; uso de alcaftadina para el tratamiento de un síntoma clínico de alergia ocular en el ojo; y kit farmacéutico.
CL2007000916A 2006-03-31 2007-04-02 Uso de alcaftadina y de acido 6,11-dihidro-11-(1-metil-4-piperidiniliden)-5h-imidazo[2,1-b][3]benzazepin-3-carboxilico, sales, n-oxidos, solvatos e hidratos para tratar sintomas de alergia ocular, inflamacion ocular y sintomas nasales de alergia ocular; composiciones oftalmicas que los comprenden; su uso y kit farmaceutico. CL2007000916A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78818506P 2006-03-31 2006-03-31
US68801607A 2007-03-19 2007-03-19

Publications (1)

Publication Number Publication Date
CL2007000916A1 true CL2007000916A1 (es) 2008-01-25

Family

ID=38468943

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2007000916A CL2007000916A1 (es) 2006-03-31 2007-04-02 Uso de alcaftadina y de acido 6,11-dihidro-11-(1-metil-4-piperidiniliden)-5h-imidazo[2,1-b][3]benzazepin-3-carboxilico, sales, n-oxidos, solvatos e hidratos para tratar sintomas de alergia ocular, inflamacion ocular y sintomas nasales de alergia ocular; composiciones oftalmicas que los comprenden; su uso y kit farmaceutico.

Country Status (29)

Country Link
US (8) US8664215B2 (es)
EP (2) EP2004196B1 (es)
JP (3) JP5292277B2 (es)
KR (1) KR101321731B1 (es)
CN (1) CN102895234A (es)
AR (1) AR060278A1 (es)
AU (1) AU2007234957B2 (es)
BR (1) BRPI0710085B8 (es)
CA (1) CA2648115C (es)
CL (1) CL2007000916A1 (es)
CR (1) CR10414A (es)
DK (2) DK2004196T3 (es)
EA (1) EA016221B1 (es)
EC (1) ECSP088786A (es)
ES (2) ES2752823T3 (es)
IL (1) IL194473A (es)
JO (1) JO3358B1 (es)
MX (1) MX2008012657A (es)
MY (1) MY153669A (es)
NI (1) NI200800261A (es)
NO (1) NO341147B1 (es)
NZ (1) NZ571690A (es)
PE (1) PE20080053A1 (es)
PL (2) PL2004196T3 (es)
SG (1) SG170044A1 (es)
TW (2) TWI450721B (es)
UY (1) UY30254A1 (es)
WO (1) WO2007117971A2 (es)
ZA (1) ZA200809327B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0710085B8 (pt) 2006-03-31 2021-05-25 Vistakon Pharmaceutical Llc composições oftálmicas e seus kits
US8685439B2 (en) 2006-04-26 2014-04-01 Aciex Therapeutics, Inc. Method for the treatment and prevention of eyelid swelling
BRPI0819105A2 (pt) * 2007-11-08 2019-09-24 Aciex Therapeutics Inc composição para o tratamento e prevenção de edema de pálpebra
CA2755679C (en) 2009-03-17 2017-09-12 Aciex Therapeutics, Inc. Ophthalmic formulations of cetirizine and methods of use
US8569273B2 (en) 2009-03-17 2013-10-29 Aciex Therapeutics, Inc. Ophthalmic formulations of cetirizine and methods of use
US12478503B2 (en) 2009-05-18 2025-11-25 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
EP2664329A1 (de) * 2012-05-15 2013-11-20 F. Holzer GmbH Ophthalmologisches Vehikelsystem
US9409913B2 (en) * 2012-11-21 2016-08-09 Enaltec Labs Private Limited Polymorphic forms of alcaftadine
US9255105B2 (en) * 2012-12-06 2016-02-09 Enaltec Labs Private Limited Process of preparing alcaftadine
SG11201901137UA (en) 2016-08-12 2019-03-28 Silk Technologies Ltd Silk-derived protein for treating inflammation
JP7191022B2 (ja) * 2017-07-28 2022-12-16 参天製薬株式会社 アルカフタジン又はその塩を含有する水性医薬組成物
JPWO2019026992A1 (ja) * 2017-08-03 2020-06-18 参天製薬株式会社 クロルヘキシジンを含有する医薬組成物
JP7309729B2 (ja) 2018-01-18 2023-07-18 ファエス・ファルマ・ソシエダッド・アノニマ ビラスチン、β－シクロデキストリンおよび少なくとも１種のゲル化剤を含有する眼科用組成物
CA3181959A1 (en) * 2020-06-15 2021-12-23 Alkem Laboratories Limited Combination of alcaftadine and a corticosteroid
EP4297707A4 (en) 2021-02-24 2025-03-19 Ocular Therapeutix, Inc. INTRACANALICULAR DEPOSIT INSERTION DEVICE
BR112023019795A2 (pt) 2021-04-01 2023-11-07 Alkem Laboratories Ltd Composições nasais compreendendo alcaftadina
WO2024010044A1 (ja) * 2022-07-06 2024-01-11 ロート製薬株式会社 眼科組成物
KR20250030490A (ko) * 2022-07-06 2025-03-05 로토 세이야쿠 가부시키가이샤 안과 조성물
CN116473937A (zh) * 2022-11-29 2023-07-25 嘉兴学院 一种具有抗恶性黑素瘤作用的仿生纳米颗粒及制备方法和应用
TW202448475A (zh) * 2023-03-31 2024-12-16 日商樂敦製藥股份有限公司 眼科組成物

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4148903A (en) 1977-07-28 1979-04-10 Merck & Co., Inc. Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines
DE3134672A1 (de) * 1981-09-02 1983-03-17 Boehringer Ingelheim KG, 6507 Ingelheim Heterocyclische verbindungen, ihre herstellung und verwendung
GB8900380D0 (en) 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
CA2093797C (en) * 1990-10-10 1998-09-22 Richard J. Friary Substituted imidazobenzazepines and imidazopyridoazepines
IT1248014B (it) * 1991-06-07 1995-01-05 Inverni Della Beffa Spa Preparazioni oftalmiche a rilascio protratto
IL101850A (en) * 1991-06-13 1996-01-31 Janssen Pharmaceutica Nv 11-(4-Piperidinyl)-imidazo (2,1-b) (3) benzazepine derivatives their preparation and pharmaceutical compositions containing them
US5641805A (en) 1995-06-06 1997-06-24 Alcon Laboratories, Inc. Topical ophthalmic formulations for treating allergic eye diseases
US20060100408A1 (en) * 2002-03-11 2006-05-11 Powell P M Method for forming contact lenses comprising therapeutic agents
US20070077303A1 (en) 2005-09-30 2007-04-05 Azaam Alli Methods for providing oxidatively stable ophthalmic compositions
US20070077302A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for stabilizing ophthalmic compositions
US8466174B2 (en) * 2006-03-17 2013-06-18 Johnson & Johnson Vision Care, Inc. Methods for stabilizing oxidatively unstable compositions
BRPI0710085B8 (pt) 2006-03-31 2021-05-25 Vistakon Pharmaceutical Llc composições oftálmicas e seus kits

Also Published As

Publication number Publication date
KR101321731B1 (ko) 2013-10-30
US20240058355A1 (en) 2024-02-22
US20230181594A1 (en) 2023-06-15
TW201446249A (zh) 2014-12-16
ES2594655T3 (es) 2016-12-21
IL194473A (en) 2016-04-21
KR20080110881A (ko) 2008-12-19
BRPI0710085B1 (pt) 2019-12-17
IL194473A0 (en) 2009-08-03
CA2648115A1 (en) 2007-10-18
DK3150209T3 (da) 2019-10-28
ECSP088786A (es) 2009-01-30
US8664215B2 (en) 2014-03-04
UY30254A1 (es) 2007-08-31
ES2752823T3 (es) 2020-04-06
US20170065605A1 (en) 2017-03-09
WO2007117971A3 (en) 2007-12-27
JP2009533333A (ja) 2009-09-17
AU2007234957B2 (en) 2012-12-13
CA2648115C (en) 2015-03-24
US20140107102A1 (en) 2014-04-17
JO3358B1 (ar) 2019-03-13
US20080051385A1 (en) 2008-02-28
TWI578990B (zh) 2017-04-21
BRPI0710085A2 (pt) 2011-08-23
NI200800261A (es) 2012-10-30
AU2007234957A1 (en) 2007-10-18
AR060278A1 (es) 2008-06-04
TW200815016A (en) 2008-04-01
MY153669A (en) 2015-03-13
JP2015131820A (ja) 2015-07-23
EA200870396A1 (ru) 2009-04-28
US20210030762A1 (en) 2021-02-04
BRPI0710085B8 (pt) 2021-05-25
DK2004196T3 (en) 2016-09-05
PE20080053A1 (es) 2008-03-10
CN102895234A (zh) 2013-01-30
TWI450721B (zh) 2014-09-01
NO341147B1 (no) 2017-09-04
MX2008012657A (es) 2009-02-19
US20250108059A1 (en) 2025-04-03
JP2013144703A (ja) 2013-07-25
EP3150209A1 (en) 2017-04-05
PL2004196T3 (pl) 2017-01-31
ZA200809327B (en) 2009-12-30
WO2007117971A2 (en) 2007-10-18
NZ571690A (en) 2011-09-30
NO20084593L (no) 2008-10-29
EP2004196A2 (en) 2008-12-24
JP6039716B2 (ja) 2016-12-07
CR10414A (es) 2009-02-23
US10617695B2 (en) 2020-04-14
PL3150209T3 (pl) 2020-03-31
EP3150209B1 (en) 2019-07-24
HK1131331A1 (en) 2010-01-22
US20120094978A1 (en) 2012-04-19
JP5292277B2 (ja) 2013-09-18
EP2004196B1 (en) 2016-06-29
EA016221B1 (ru) 2012-03-30
SG170044A1 (en) 2011-04-29

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