[go: up one dir, main page]

CL2004001458A1 - Compuestos derivados de 3-(guanidinocarbonil) heterociclos, composicion farmaceutica, procedimiento de preparacion, utiles para preparar un medicamento para tratar trastornos fibroticos de higado, rinon, de organos internos, trastornos inflamatorios, - Google Patents

Compuestos derivados de 3-(guanidinocarbonil) heterociclos, composicion farmaceutica, procedimiento de preparacion, utiles para preparar un medicamento para tratar trastornos fibroticos de higado, rinon, de organos internos, trastornos inflamatorios,

Info

Publication number
CL2004001458A1
CL2004001458A1 CL200401458A CL2004001458A CL2004001458A1 CL 2004001458 A1 CL2004001458 A1 CL 2004001458A1 CL 200401458 A CL200401458 A CL 200401458A CL 2004001458 A CL2004001458 A CL 2004001458A CL 2004001458 A1 CL2004001458 A1 CL 2004001458A1
Authority
CL
Chile
Prior art keywords
heterociclos
guanidinocarbonil
rinon
disorders
prepare
Prior art date
Application number
CL200401458A
Other languages
English (en)
Inventor
Jean-Christophe Doerflin Carry
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of CL2004001458A1 publication Critical patent/CL2004001458A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Surgery (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CL200401458A 2003-06-12 2004-06-11 Compuestos derivados de 3-(guanidinocarbonil) heterociclos, composicion farmaceutica, procedimiento de preparacion, utiles para preparar un medicamento para tratar trastornos fibroticos de higado, rinon, de organos internos, trastornos inflamatorios, CL2004001458A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0307080A FR2856062B1 (fr) 2003-06-12 2003-06-12 Derives 3-guanidinocarbonyl-heterocycle, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
CL2004001458A1 true CL2004001458A1 (es) 2005-05-20

Family

ID=33484382

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200401458A CL2004001458A1 (es) 2003-06-12 2004-06-11 Compuestos derivados de 3-(guanidinocarbonil) heterociclos, composicion farmaceutica, procedimiento de preparacion, utiles para preparar un medicamento para tratar trastornos fibroticos de higado, rinon, de organos internos, trastornos inflamatorios,

Country Status (20)

Country Link
EP (1) EP1641791B1 (es)
JP (1) JP2006527220A (es)
AR (1) AR044661A1 (es)
AT (1) ATE437877T1 (es)
AU (1) AU2004247350B2 (es)
BR (1) BRPI0411343A (es)
CA (1) CA2528382A1 (es)
CL (1) CL2004001458A1 (es)
DE (1) DE602004022299D1 (es)
DK (1) DK1641791T3 (es)
ES (1) ES2330524T3 (es)
FR (1) FR2856062B1 (es)
IL (1) IL172435A0 (es)
MX (1) MXPA05012970A (es)
MY (1) MY138896A (es)
PE (1) PE20050228A1 (es)
PT (1) PT1641791E (es)
TW (1) TW200524926A (es)
UY (1) UY28358A1 (es)
WO (1) WO2004111048A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2599688A1 (en) * 2005-03-01 2006-09-08 Wyeth Cinnoline compounds and their use as liver x receptor modulators
CA2661436A1 (en) * 2006-08-24 2008-02-28 Serenex, Inc. Isoquinoline, quinazoline and phthalazine derivatives
JP2011148751A (ja) * 2010-01-25 2011-08-04 Konica Minolta Holdings Inc 含窒素縮合複素環化合物の製造方法
CN102603740B (zh) * 2012-03-01 2014-05-14 南京药石药物研发有限公司 4-硝基-7-氮杂吲哚的合成方法
CN105218546B (zh) * 2015-11-04 2017-05-17 上海泰坦科技股份有限公司 1h‑吡咯并[2,3‑b]吡啶‑3‑羧酸甲酯的合成工艺

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3162572B2 (ja) * 1993-04-28 2001-05-08 住友製薬株式会社 インドロイルグアニジン誘導体
CA2121391A1 (en) * 1993-04-28 1994-10-29 Atsuyuki Kojima Indoloylguanidine derivatives
EP0639573A1 (de) * 1993-08-03 1995-02-22 Hoechst Aktiengesellschaft Benzokondensierte 5-Ringheterocyclen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, ihre Verwendung als Diagnostikum, sowie sie enthaltendes Medikament
JPH08208602A (ja) * 1994-10-18 1996-08-13 Sumitomo Pharmaceut Co Ltd インドロイルグアニジン誘導体
CA2160600A1 (en) * 1994-10-18 1996-04-19 Masahumi Kitano Indoloylguanidine derivatives
JPH09278767A (ja) * 1996-02-15 1997-10-28 Fujisawa Pharmaceut Co Ltd 新規グアニジン誘導体
DE19622222A1 (de) * 1996-06-03 1997-12-04 Hoechst Ag Verwendung von Inhibitoren des zellulären Na·+·/H·+·-Exchangers (NHE) zur Herstellung eines Medikament zur Normalisierung der Serumlipide
US6258829B1 (en) * 1997-03-06 2001-07-10 Toa Eiyo Ltd. Cycloalka[b]pyridine-3-carbonylguanidine derivatives, process for producing the same, and drugs containing the same

Also Published As

Publication number Publication date
UY28358A1 (es) 2004-12-31
FR2856062B1 (fr) 2005-11-11
BRPI0411343A (pt) 2006-07-11
PE20050228A1 (es) 2005-05-17
TW200524926A (en) 2005-08-01
EP1641791A1 (en) 2006-04-05
DE602004022299D1 (de) 2009-09-10
EP1641791B1 (en) 2009-07-29
DK1641791T3 (da) 2009-11-16
MXPA05012970A (es) 2006-05-25
ATE437877T1 (de) 2009-08-15
WO2004111048A1 (en) 2004-12-23
AU2004247350A1 (en) 2004-12-23
FR2856062A1 (fr) 2004-12-17
PT1641791E (pt) 2009-09-29
AR044661A1 (es) 2005-09-21
AU2004247350B2 (en) 2009-07-23
JP2006527220A (ja) 2006-11-30
CA2528382A1 (en) 2004-12-23
MY138896A (en) 2009-08-28
ES2330524T3 (es) 2009-12-11
IL172435A0 (en) 2006-04-10

Similar Documents

Publication Publication Date Title
EA200801998A1 (ru) ПИРИДИН[3,4-b]ПИРАЗИНОНЫ
BRPI0513843A (pt) composto ou um sal ou solvato ou uma pró-droga farmaceuticamente aceitável do mesmo, composição farmacêutica, forma de dosagem, uso de um composto, e, sal de cloridrato
TWI369987B (en) New pharmaceutical compositions for the treatment of hyper-proliferative disorders
BRPI0409109A (pt) novos compostos
CL2007003049A1 (es) Compuestos derivados de 2,4-diaminopirimidina; composicion farmaceutica, utiles para tratar trastornos proliferativos.
DE502004008604D1 (de) Pyrrolopyridin-substitutierte benzol-derivate zur behandlung kardiovaskulärer erkrankungen
JP2009506117A5 (es)
NO2014009I2 (no) Forbindelser, farmasøytiske sammensetninger og anvendelser derav, samt fremgangsmåte for å fremstille nevnte forbindelser
EA200802058A1 (ru) Производные циклоалкиламинокислот и их фармацевтические композиции
IL178730A0 (en) New pharmaceutical compositions for the treatment of sexual disorders ii
EP1924318A4 (en) SYNCHRONIZATION OF REPETITIVE THERAPEUTIC INTERVENTION
IL173908A0 (en) Pharmaceutical compositions for treating premature ejaculation by pulmonary inhalation
CL2004000798A1 (es) COMPUESTOS DERIVADOS DE BENZO[b]TIOFENO, BENZODIOXOL, BENZOFURANO, SUS SALES FARMACEUTICAMENTE ACEPTABLES, COMPOSICION FARMACEUTICA, UTILES PARA TRATAR LA ATEROSCLEROSIS.
WO2005037798A3 (en) Amide or thiomide derivatives and their use in the treatment of pain
DK3072507T3 (da) Farmaceutiske sammensætninger til glukokortikoidsubstitutionsterapi
WO2007057221A3 (en) Pharmaceutical compositions for the treatment of inflammatory and obstructive airways diseases
DK1673077T3 (da) Farmaceutiske præparater, der omfatter malonamidderivater til at nedsætte talgproduktion
WO2007009721A3 (en) Indoline-substituted pyrazoline derivatives, their preparation and use as medicaments
ATE495159T1 (de) Diaminocyclohexan- und diaminocyclopentanderivate
CL2004001458A1 (es) Compuestos derivados de 3-(guanidinocarbonil) heterociclos, composicion farmaceutica, procedimiento de preparacion, utiles para preparar un medicamento para tratar trastornos fibroticos de higado, rinon, de organos internos, trastornos inflamatorios,
IL201491A (en) Aryl Sulfonamide Amino Alkoxy Compounds, Preparation Process, and Pharmaceutical Preparations Containing Them
WO2006063294A3 (en) Novel inhibitors of histone deacetylase for the treatment of disease
BRPI0509524A (pt) formas cristalinas de n-desmetilclozapina
ITFI20050041A1 (it) Idrossammati come inibitori dell'istone deacelitasi, loro preparazione e formulazioni farmaceutiche che li contengono
WO2008039894A3 (en) Atorvastatin pharmaceutical compositions