CL2003002762A1 - COMPOUNDS DERIVED FROM PIRROLOPIRIMIDINA OR PIRROLOPIRIDINA REPLACED BY A CYCLIC AMINE, ITS SALTS; PHARMACEUTICAL COMPOSITION; AND ITS USE TO PREPARE AN ANTAGONIST OF CRF RECEIVERS, TO TREAT DISEASES AS DEPRESSION, ANXIETY, ALZ - Google Patents

COMPOUNDS DERIVED FROM PIRROLOPIRIMIDINA OR PIRROLOPIRIDINA REPLACED BY A CYCLIC AMINE, ITS SALTS; PHARMACEUTICAL COMPOSITION; AND ITS USE TO PREPARE AN ANTAGONIST OF CRF RECEIVERS, TO TREAT DISEASES AS DEPRESSION, ANXIETY, ALZ

Info

Publication number: CL2003002762A1
Authority: CL; Chile
Prior art keywords: pirrolopirimidina; pirrolopiridina; alz; crf; anxiety
Prior art date: 2002-12-26

Application number

CL200302762A

Other languages

Spanish (es)

Inventor

Atsuro Okubo Taketosh Nakazato

Original Assignee

Taisho Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-26

Filing date

2003-12-26

Publication date

2005-04-08

2003-12-26 Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd

2005-04-08 Publication of CL2003002762A1 publication Critical patent/CL2003002762A1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Dermatology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Psychology (AREA)
Addiction (AREA)
Rheumatology (AREA)
Immunology (AREA)
Hospice & Palliative Care (AREA)
Nutrition Science (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)

CL200302762A 2002-12-26 2003-12-26 COMPOUNDS DERIVED FROM PIRROLOPIRIMIDINA OR PIRROLOPIRIDINA REPLACED BY A CYCLIC AMINE, ITS SALTS; PHARMACEUTICAL COMPOSITION; AND ITS USE TO PREPARE AN ANTAGONIST OF CRF RECEIVERS, TO TREAT DISEASES AS DEPRESSION, ANXIETY, ALZ CL2003002762A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2002383667		2002-12-26

Publications (1)

Publication Number	Publication Date
CL2003002762A1 true CL2003002762A1 (en)	2005-04-08

Family

ID=32677471

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CL200302762A CL2003002762A1 (en)	2002-12-26	2003-12-26	COMPOUNDS DERIVED FROM PIRROLOPIRIMIDINA OR PIRROLOPIRIDINA REPLACED BY A CYCLIC AMINE, ITS SALTS; PHARMACEUTICAL COMPOSITION; AND ITS USE TO PREPARE AN ANTAGONIST OF CRF RECEIVERS, TO TREAT DISEASES AS DEPRESSION, ANXIETY, ALZ

Country Status (23)

Country	Link
US (3)	US20050209253A1 (en)
EP (2)	EP1787992B1 (en)
JP (1)	JP4181126B2 (en)
KR (2)	KR100688395B1 (en)
CN (1)	CN1692115A (en)
AR (1)	AR042667A1 (en)
AT (2)	ATE390426T1 (en)
AU (1)	AU2003292550B8 (en)
BR (1)	BR0307587A (en)
CA (1)	CA2485556C (en)
CL (1)	CL2003002762A1 (en)
DE (2)	DE60319951T2 (en)
EA (1)	EA200401060A1 (en)
ES (2)	ES2302949T3 (en)
HR (1)	HRP20040724A2 (en)
MX (1)	MXPA04008081A (en)
MY (1)	MY141200A (en)
NO (1)	NO20043508L (en)
PL (1)	PL371810A1 (en)
TW (1)	TWI270549B (en)
UA (1)	UA77265C2 (en)
WO (1)	WO2004058767A1 (en)
ZA (1)	ZA200405982B (en)

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CN1910187A (en)	2004-01-06	2007-02-07	大正制药株式会社	Triaza-cyclopenta [cd] indene derivatives
RU2367663C2 (en) *	2004-01-06	2009-09-20	Тайсо Фармасьютикал Ко., Лтд.	Pyrrolopyrimidine and pyrrolotriazine derivatives
US7557111B2 (en)	2004-01-06	2009-07-07	Taisho Pharmaceutical Co., Ltd.	Substituted thieno[3,2-d]pyrimidines as CRF receptor antagonists
CN1926140A (en) *	2004-03-05	2007-03-07	大正制药株式会社	Pyrrolopyrimidine derivatives
JP2008503443A (en) *	2004-06-25	2008-02-07	大正製薬株式会社	Derivatives of pyrrolopyrimidine and pyrrolopyridine substituted with tetrahydropyridine
JP2007161585A (en)	2004-06-25	2007-06-28	Taisho Pharmaceut Co Ltd	Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino groups
DE102004042607A1 (en) *	2004-09-03	2006-03-09	Bayer Healthcare Ag	Substituted phenylaminothiazoles and their use
DE102006042143A1 (en) *	2006-09-08	2008-03-27	Bayer Healthcare Aktiengesellschaft	Novel substituted bipyridine derivatives and their use
DE102006056739A1 (en) *	2006-12-01	2008-06-05	Bayer Healthcare Ag	Substituted 4-amino-3,5-dicyano-2-thiopyridines and their use
DE102006056740A1 (en) *	2006-12-01	2008-06-05	Bayer Healthcare Ag	Cyclic substituted 3,5-dicyano-2-thiopyridines and their use
ES2559319T3 (en)	2007-06-04	2016-02-11	Synergy Pharmaceuticals Inc.	Guanylate cliclas agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
DE102007035367A1 (en) *	2007-07-27	2009-01-29	Bayer Healthcare Ag	Substituted aryloxazoles and their use
DE102007036076A1 (en)	2007-08-01	2009-02-05	Bayer Healthcare Aktiengesellschaft	Dipeptoid Produgs and their use
DE102007061764A1 (en) *	2007-12-20	2009-06-25	Bayer Healthcare Ag	Anellated cyanopyridines and their use
DE102007061763A1 (en) *	2007-12-20	2009-06-25	Bayer Healthcare Ag	Substituted azabicyclic compounds and their use
DE102008013587A1 (en) *	2008-03-11	2009-09-17	Bayer Schering Pharma Aktiengesellschaft	Heteroaryl-substituted dicyanopyridines and their use
CL2009001152A1 (en)	2008-05-13	2009-10-16	Array Biopharma Inc	Compounds derived from n- (4- (nitrogen cycloalkyl-1-yl) -1h-pyrrolo [2,3-b] pyridin-3-yl) amide, kinase inhibitors; Preparation process; pharmaceutical composition; and its use for the treatment of a proliferative disease.
EP2297104B1 (en) *	2008-05-29	2013-08-07	Bayer Intellectual Property GmbH	2-alkoxy-substituted dicyanopyridines and use thereof
CA2726917C (en)	2008-06-04	2018-06-26	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP3241839B1 (en)	2008-07-16	2019-09-04	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
DE102008062567A1 (en)	2008-12-16	2010-06-17	Bayer Schering Pharma Aktiengesellschaft	Dipeptoid prodrugs and their use
DE102009006602A1 (en) *	2009-01-29	2010-08-05	Bayer Schering Pharma Aktiengesellschaft	Alkylamino-substituted dicyanopyridines and their amino acid ester prodrugs
DE102010030688A1 (en)	2010-06-30	2012-01-05	Bayer Schering Pharma Aktiengesellschaft	Substituted dicyanopyridines and their use
US20120058983A1 (en)	2010-09-02	2012-03-08	Bayer Pharma Aktiengesellschaft	Adenosine A1 agonists for the treatment of glaucoma and ocular hypertension
MX345780B (en)	2011-03-15	2017-02-15	Trius Therapeutics Inc	Tricyclic gyrase inhibitors.
CA2905438A1 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
EP2968439A2 (en)	2013-03-15	2016-01-20	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
EA027860B1 (en)	2013-04-11	2017-09-29	Ф. Хоффманн-Ля Рош Аг	Inhibitors of beta-secretase 1 (bace1)
PT2991988T (en) *	2013-05-02	2017-07-25	Hoffmann La Roche	Pyrrolo[2,3-d]pyrimidine derivatives as cb2 receptor agonists
CN114829362A (en) *	2019-12-10	2022-07-29	成都倍特药业股份有限公司	Six-membered and five-membered aromatic ring derivative containing nitrogen heteroatom and used as SHP2 inhibitor
CN114646700B (en) *	2022-03-01	2023-10-20	浙江国邦药业有限公司	Detection method of (S) -pyrrolidine-2-formonitrile hydrochloride

Family Cites Families (7)

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Publication number	Priority date	Publication date	Assignee	Title
ATE177101T1 (en)	1992-12-17	1999-03-15	Pfizer	PYRROLOPYRIMIDINES AS CRF ANTAGONISTS
US5646152A (en)	1994-06-15	1997-07-08	Pfizer Inc.	Methods of administering CRF antagonists
DE69510940T2 (en)	1994-06-16	1999-11-11	Pfizer Inc., New York	PYRAZOLO AND PYRROLOPYRIDINE
US6187781B1 (en) *	1997-03-26	2001-02-13	Taisho Pharmaceutical Co., Ltd.	4-Tetrahydropyridylpyrimidine derivatives
AU756702B2 (en)	1999-03-11	2003-01-23	Taisho Pharmaceutical Co., Ltd.	Carbamoyl tetrahydropyridine derivatives
AR028782A1 (en) *	2000-07-05	2003-05-21	Taisho Pharmaceutical Co Ltd	TETRAHYDROPIRIDINE OR PIPERIDINE HETEROCICLIC DERIVATIVES
CN1910187A (en) *	2004-01-06	2007-02-07	大正制药株式会社	Triaza-cyclopenta [cd] indene derivatives

2003
- 2003-12-23 AR ARP030104818A patent/AR042667A1/en unknown
- 2003-12-23 TW TW092136594A patent/TWI270549B/en not_active IP Right Cessation
- 2003-12-24 EP EP06019987A patent/EP1787992B1/en not_active Expired - Lifetime
- 2003-12-24 AT AT03768186T patent/ATE390426T1/en not_active IP Right Cessation
- 2003-12-24 PL PL03371810A patent/PL371810A1/en not_active Application Discontinuation
- 2003-12-24 WO PCT/JP2003/016598 patent/WO2004058767A1/en not_active Ceased
- 2003-12-24 DE DE60319951T patent/DE60319951T2/en not_active Expired - Lifetime
- 2003-12-24 HR HR20040724A patent/HRP20040724A2/en not_active Application Discontinuation
- 2003-12-24 ES ES03768186T patent/ES2302949T3/en not_active Expired - Lifetime
- 2003-12-24 DE DE60327477T patent/DE60327477D1/en not_active Expired - Lifetime
- 2003-12-24 AU AU2003292550A patent/AU2003292550B8/en not_active Ceased
- 2003-12-24 MX MXPA04008081A patent/MXPA04008081A/en active IP Right Grant
- 2003-12-24 AT AT06019987T patent/ATE430151T1/en not_active IP Right Cessation
- 2003-12-24 KR KR1020047013348A patent/KR100688395B1/en not_active Expired - Fee Related
- 2003-12-24 MY MYPI20034990A patent/MY141200A/en unknown
- 2003-12-24 EP EP03768186A patent/EP1467997B8/en not_active Expired - Lifetime
- 2003-12-24 US US10/504,981 patent/US20050209253A1/en not_active Abandoned
- 2003-12-24 ES ES06019987T patent/ES2325596T3/en not_active Expired - Lifetime
- 2003-12-24 EA EA200401060A patent/EA200401060A1/en unknown
- 2003-12-24 CN CNA2003801004264A patent/CN1692115A/en active Pending
- 2003-12-24 UA UA20040907464A patent/UA77265C2/en unknown
- 2003-12-24 CA CA002485556A patent/CA2485556C/en not_active Expired - Fee Related
- 2003-12-24 KR KR1020067025000A patent/KR100808756B1/en not_active Expired - Fee Related
- 2003-12-24 BR BR0307587-7A patent/BR0307587A/en not_active IP Right Cessation
- 2003-12-24 JP JP2004562918A patent/JP4181126B2/en not_active Expired - Fee Related
- 2003-12-26 CL CL200302762A patent/CL2003002762A1/en unknown
2004
- 2004-07-27 ZA ZA200405982A patent/ZA200405982B/en unknown
- 2004-08-23 NO NO20043508A patent/NO20043508L/en not_active Application Discontinuation
2008
- 2008-04-21 US US12/106,873 patent/US7932259B2/en not_active Expired - Fee Related
2010
- 2010-11-22 US US12/951,556 patent/US8455511B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
UA77265C2 (en)	2006-11-15
BR0307587A (en)	2005-02-01
ATE390426T1 (en)	2008-04-15
ES2325596T3 (en)	2009-09-09
JP2005539090A (en)	2005-12-22
AU2003292550A1 (en)	2004-07-22
AR042667A1 (en)	2005-06-29
KR100808756B1 (en)	2008-02-29
EP1787992A1 (en)	2007-05-23
US7932259B2 (en)	2011-04-26
EP1467997B1 (en)	2008-03-26
KR100688395B1 (en)	2007-03-02
ATE430151T1 (en)	2009-05-15
US8455511B2 (en)	2013-06-04
TW200505921A (en)	2005-02-16
ES2302949T3 (en)	2008-08-01
KR20060128063A (en)	2006-12-13
EP1467997B8 (en)	2008-08-27
DE60327477D1 (en)	2009-06-10
NO20043508L (en)	2004-10-07
US20050209253A1 (en)	2005-09-22
PL371810A1 (en)	2005-06-27
AU2003292550B2 (en)	2006-09-21
TWI270549B (en)	2007-01-11
EP1467997A1 (en)	2004-10-20
EP1787992B1 (en)	2009-04-29
KR20040111369A (en)	2004-12-31
CA2485556A1 (en)	2004-07-15
ZA200405982B (en)	2005-09-02
US20080287397A1 (en)	2008-11-20
DE60319951D1 (en)	2008-05-08
WO2004058767A1 (en)	2004-07-15
CN1692115A (en)	2005-11-02
DE60319951T2 (en)	2009-05-20
US20110130364A1 (en)	2011-06-02
MXPA04008081A (en)	2004-11-26
JP4181126B2 (en)	2008-11-12
EA200401060A1 (en)	2005-02-24
HRP20040724A2 (en)	2004-10-31
AU2003292550B8 (en)	2006-11-09
CA2485556C (en)	2006-01-10
MY141200A (en)	2010-03-31

Publication	Publication Date	Title
CL2003002762A1 (en)	2005-04-08	COMPOUNDS DERIVED FROM PIRROLOPIRIMIDINA OR PIRROLOPIRIDINA REPLACED BY A CYCLIC AMINE, ITS SALTS; PHARMACEUTICAL COMPOSITION; AND ITS USE TO PREPARE AN ANTAGONIST OF CRF RECEIVERS, TO TREAT DISEASES AS DEPRESSION, ANXIETY, ALZ
BRPI0514681A (en)	2008-06-17	pyrimidine derivatives
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