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CH451120A - Process for the preparation of tricyclic amines - Google Patents

Process for the preparation of tricyclic amines

Info

Publication number
CH451120A
CH451120A CH800963A CH800963A CH451120A CH 451120 A CH451120 A CH 451120A CH 800963 A CH800963 A CH 800963A CH 800963 A CH800963 A CH 800963A CH 451120 A CH451120 A CH 451120A
Authority
CH
Switzerland
Prior art keywords
preparation
tricyclic amines
tricyclic
amines
Prior art date
Application number
CH800963A
Other languages
German (de)
Inventor
Gerald Dr Rey-Bellet
Hans Dr Spiegelberg
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25702636&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CH451120(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US266807A external-priority patent/US3157640A/en
Priority to CH1751366A priority Critical patent/CH495311A/en
Priority to CH800963A priority patent/CH451120A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to BE645315A priority patent/BE645315A/xx
Priority to FR967773A priority patent/FR1543163A/en
Priority to GB1115564A priority patent/GB1011843A/en
Priority to DE19641468034 priority patent/DE1468034A1/en
Priority to DE19641768746 priority patent/DE1768746A1/en
Priority to DE19641768747 priority patent/DE1768747A1/en
Priority to US373527A priority patent/US3271389A/en
Priority to FR977998A priority patent/FR3431M/en
Priority to IL2155864A priority patent/IL21558A/en
Priority to NL6407095A priority patent/NL6407095A/xx
Priority to SE07645/64A priority patent/SE328276B/xx
Priority to BR16032364A priority patent/BR6460323D0/en
Priority to SE236766A priority patent/SE337368B/xx
Priority to BE649716A priority patent/BE649716A/xx
Priority to GB1190466A priority patent/GB1065605A/en
Priority to GB1190366A priority patent/GB1065604A/en
Priority to GB2648964A priority patent/GB1065602A/en
Priority to GB1190666A priority patent/GB1065606A/en
Priority to GB1190266A priority patent/GB1065603A/en
Priority to ES301516A priority patent/ES301516A1/en
Priority to DK325464A priority patent/DK119205C/en
Priority to DK258765A priority patent/DK127058B/en
Publication of CH451120A publication Critical patent/CH451120A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/48Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
    • C07D499/58Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
    • C07D499/64Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
    • C07D499/68Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH800963A 1963-03-21 1963-06-28 Process for the preparation of tricyclic amines CH451120A (en)

Priority Applications (24)

Application Number Priority Date Filing Date Title
CH1751366A CH495311A (en) 1963-03-21 1963-06-28 Antioxidant chromane derivs
CH800963A CH451120A (en) 1963-03-21 1963-06-28 Process for the preparation of tricyclic amines
BE645315A BE645315A (en) 1963-03-21 1964-03-17
FR967773A FR1543163A (en) 1963-03-21 1964-03-17 Manufacturing process of d - (-) - alpha-aminobenzylpenicillin trihydrate
GB1115564A GB1011843A (en) 1963-03-21 1964-03-17 D-(-)-ª‡-aminobenzylpenicillin trihydrate
DE19641468034 DE1468034A1 (en) 1963-03-21 1964-06-02 Process for the preparation of tricyclic amines
DE19641768747 DE1768747A1 (en) 1963-03-21 1964-06-02 Tricyclic compounds
DE19641768746 DE1768746A1 (en) 1963-03-21 1964-06-02 Tricyclic compounds
US373527A US3271389A (en) 1963-03-21 1964-06-08 Process for the isolation of certain basic penicillins
FR977998A FR3431M (en) 1963-03-21 1964-06-12 Medicinal product based on tricyclic amines.
IL2155864A IL21558A (en) 1963-03-21 1964-06-17 Tricyclic compounds
NL6407095A NL6407095A (en) 1963-03-21 1964-06-22
SE236766A SE337368B (en) 1963-03-21 1964-06-24
SE07645/64A SE328276B (en) 1963-03-21 1964-06-24
BR16032364A BR6460323D0 (en) 1963-03-21 1964-06-24 PROCESS FOR THE PREPARATION OF TRICYCLIC AMINES
BE649716A BE649716A (en) 1963-03-21 1964-06-25
GB1190466A GB1065605A (en) 1963-03-21 1964-06-26 Novel 5-propenylidene-debenzocycloheptatriene derivatives and a process for the preparation thereof
GB1190366A GB1065604A (en) 1963-03-21 1964-06-26 Novel 5-(chloro-propylidene)-dibenzocycloheptatriene derivatives and a process for the preparation thereof
GB2648964A GB1065602A (en) 1963-03-21 1964-06-26 Novel substituted 5-(amino-propylidene)-dibenzo[a,d]-cyclohepta[1,4,6]trienes and the manufacture thereof
GB1190666A GB1065606A (en) 1963-03-21 1964-06-26 Novel 5-(3-alkoxy-propylidene)-dibenzocycloheptatriene derivatives and a process for the preparation thereof
GB1190266A GB1065603A (en) 1963-03-21 1964-06-26 Novel 5-(amino-propyl)-dibenzocycloheptatriene derivatives and a process for the preparation thereof
ES301516A ES301516A1 (en) 1963-06-28 1964-06-27 Procedure for the preparation of tricyclic amines (Machine-translation by Google Translate, not legally binding)
DK325464A DK119205C (en) 1963-03-21 1964-06-29 Process for the preparation of halogen-containing, basic substituted dibenzocycloheptatriene compounds or acid addition salts thereof.
DK258765A DK127058B (en) 1963-03-21 1965-05-21 Analogous process for the preparation of halogen-containing basic substituted dibenzocycloheptatriene compounds or acid addition salts.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US266807A US3157640A (en) 1963-03-21 1963-03-21 D-(-)-alpha-aminobenzylpenicillin trihydrate
CH800963A CH451120A (en) 1963-03-21 1963-06-28 Process for the preparation of tricyclic amines

Publications (1)

Publication Number Publication Date
CH451120A true CH451120A (en) 1968-05-15

Family

ID=25702636

Family Applications (1)

Application Number Title Priority Date Filing Date
CH800963A CH451120A (en) 1963-03-21 1963-06-28 Process for the preparation of tricyclic amines

Country Status (10)

Country Link
BE (2) BE645315A (en)
BR (1) BR6460323D0 (en)
CH (1) CH451120A (en)
DE (3) DE1768746A1 (en)
DK (2) DK119205C (en)
FR (1) FR3431M (en)
GB (6) GB1011843A (en)
IL (1) IL21558A (en)
NL (1) NL6407095A (en)
SE (2) SE328276B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758577A (en) * 1984-04-05 1988-07-19 Merck & Co., Inc. 4-(5H-dibenzo[a,d]cyclohepten-5-yl)piperidine compounds for treating cardiovascular disorders

Also Published As

Publication number Publication date
SE337368B (en) 1971-08-09
IL21558A (en) 1968-01-25
DK119205C (en) 1970-11-30
DK119205B (en) 1970-11-30
DE1768746A1 (en) 1972-05-10
GB1011843A (en) 1965-12-01
FR3431M (en) 1965-07-12
BE649716A (en) 1964-12-28
BE645315A (en) 1964-09-17
GB1065602A (en) 1967-04-19
GB1065603A (en) 1967-04-19
DE1468034A1 (en) 1968-12-19
BR6460323D0 (en) 1973-08-09
DK127058B (en) 1973-09-17
GB1065605A (en) 1967-04-19
GB1065606A (en) 1967-04-19
SE328276B (en) 1970-09-14
DE1768747A1 (en) 1972-04-20
NL6407095A (en) 1964-12-29
GB1065604A (en) 1967-04-19

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