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CH177815A - Process for the preparation of an imidazole derivative. - Google Patents

Process for the preparation of an imidazole derivative.

Info

Publication number
CH177815A
CH177815A CH177815DA CH177815A CH 177815 A CH177815 A CH 177815A CH 177815D A CH177815D A CH 177815DA CH 177815 A CH177815 A CH 177815A
Authority
CH
Switzerland
Prior art keywords
imidazole derivative
preparation
benzimidazole
water
ester
Prior art date
Application number
Other languages
German (de)
Inventor
Gesellschaft Fuer Chemis Basel
Original Assignee
Chem Ind Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Ind Basel filed Critical Chem Ind Basel
Publication of CH177815A publication Critical patent/CH177815A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

  

  Verfahren zur Herstellung eines     Imidazolderivates.       Es wurde gefunden, dass man ein neues       Imidazolderivat    erhält, wenn man     Benzimid-          azol    mit einem Ester des     Cetylalkohols    be  handelt. Das neue     Imidazolderivat    verbindet  sich mit Mineralsäuren zu Salzen, zum Bei  spiel mit Salzsäure     zurr        N.Cetyl-benzimid-          azolhydrochlorid,    das mit Wasser stark  schäumende Lösungen gibt und ein ausge  zeichnetes     Weichmachungsrnittel    für Viskose  kunstseide darstellt.  



  <I>Beispiel</I>  <B>183</B> Teile     Benzimidazol    werden mit 260  Teilen     Cetylchlorid    während etwa 8 Stunden  bei<B>160</B>   gerührt. Sobald eine Probe der  Reaktionsmasse sich in angesäuertem Wasser  klar löst, unterbricht man das weitere Er  hitzen, wobei nach dem Erkalten das Reak-         tionsprodukt    als eine talgige Masse erhalten  wird, die nötigenfalls durch Aufnahme in  Alkohol und Entfärben mit Tierkohle völlig  entfärbt werden kann.



  Process for the preparation of an imidazole derivative. It has been found that a new imidazole derivative is obtained when benzimidazole is treated with an ester of cetyl alcohol. The new imidazole derivative combines with mineral acids to form salts, for example with hydrochloric acid for N.Cetyl-benzimid-azole hydrochloride, which gives strong foaming solutions with water and is an excellent softening agent for viscose rayon.



  <I> Example </I> <B> 183 parts of benzimidazole are stirred with 260 parts of cetyl chloride for about 8 hours at <B> 160 </B>. As soon as a sample of the reaction mass dissolves clearly in acidified water, further heating is interrupted, whereby after cooling the reaction product is obtained as a tallowy mass which, if necessary, can be completely decolorized by being absorbed in alcohol and decolorizing with animal charcoal.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung eines neuen Imidazolderivates, dadurch gekennzeichnet, dass man Benzimidazol mit einem Ester des Cetylalkohols behandelt. Das Treue Imidazol- derivat verbindet sich mit Mineralsäuren zu Salzen, zum Beispiel mit Salzsäure zum N- Cetyl-benzimidazolhydrochlorid, das mit Was ser stark schäumende Lösungen gibt und ein ausgezeichnetes Weichmachungsmittel für Viskosekunstseide darstellt. PATENT CLAIM: Process for the production of a new imidazole derivative, characterized in that benzimidazole is treated with an ester of cetyl alcohol. The Faithful imidazole derivative combines with mineral acids to form salts, for example with hydrochloric acid to form N-cetylbenzimidazole hydrochloride, which gives highly foaming solutions with water and is an excellent plasticizer for viscose rayon.
CH177815D 1933-12-15 1933-12-15 Process for the preparation of an imidazole derivative. CH177815A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH175673T 1933-12-15
CH177815T 1933-12-15

Publications (1)

Publication Number Publication Date
CH177815A true CH177815A (en) 1935-06-15

Family

ID=25719717

Family Applications (1)

Application Number Title Priority Date Filing Date
CH177815D CH177815A (en) 1933-12-15 1933-12-15 Process for the preparation of an imidazole derivative.

Country Status (1)

Country Link
CH (1) CH177815A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0262343A3 (en) * 1986-08-07 1990-12-19 Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg N-alkylated quaternary nitrogen-containing heterocycles, process for their preparation and their use in pharmaceutical compositions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0262343A3 (en) * 1986-08-07 1990-12-19 Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg N-alkylated quaternary nitrogen-containing heterocycles, process for their preparation and their use in pharmaceutical compositions

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