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CA3239717A1 - Composes heterocycliques utilises comme inhibiteurs des kinases gcn2 et perk - Google Patents

Composes heterocycliques utilises comme inhibiteurs des kinases gcn2 et perk Download PDF

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Publication number
CA3239717A1
CA3239717A1 CA3239717A CA3239717A CA3239717A1 CA 3239717 A1 CA3239717 A1 CA 3239717A1 CA 3239717 A CA3239717 A CA 3239717A CA 3239717 A CA3239717 A CA 3239717A CA 3239717 A1 CA3239717 A1 CA 3239717A1
Authority
CA
Canada
Prior art keywords
cancer
compound
group
patient
leukemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3239717A
Other languages
English (en)
Inventor
Yu Mi Ahn
Gada AL-ANI
Daniel L. Flynn
Salim JAVED
Patrick Kearney
Bertrand Le Bourdonnec
Kristen STOLTZ
Jeffery ZWICKER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deciphera Pharmaceuticals LLC
Original Assignee
Deciphera Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deciphera Pharmaceuticals LLC filed Critical Deciphera Pharmaceuticals LLC
Priority claimed from PCT/US2022/051717 external-priority patent/WO2023102228A1/fr
Publication of CA3239717A1 publication Critical patent/CA3239717A1/fr
Pending legal-status Critical Current

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Abstract

L'invention concerne des composés de formule L-A, qui sont des inhibiteurs de la kinase GCN2 ou de la kinase PERK, et des méthodes de traitement de maladies, notamment de maladies associées à la kinase GCN2 ou à la kinase PERK, faisant appel auxdits composés.
CA3239717A 2021-12-03 2022-12-02 Composes heterocycliques utilises comme inhibiteurs des kinases gcn2 et perk Pending CA3239717A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163285833P 2021-12-03 2021-12-03
US63/285,833 2021-12-03
PCT/US2022/051717 WO2023102228A1 (fr) 2021-12-03 2022-12-02 Composés hétérocycliques utilisés comme inhibiteurs des kinases gcn2 et perk

Publications (1)

Publication Number Publication Date
CA3239717A1 true CA3239717A1 (fr) 2023-06-08

Family

ID=91269405

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3239717A Pending CA3239717A1 (fr) 2021-12-03 2022-12-02 Composes heterocycliques utilises comme inhibiteurs des kinases gcn2 et perk

Country Status (1)

Country Link
CA (1) CA3239717A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117100754A (zh) * 2023-09-05 2023-11-24 暨南大学 Vps34抑制剂在制备防治蒽环类药物诱导心脏毒性的药物中的应用

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117100754A (zh) * 2023-09-05 2023-11-24 暨南大学 Vps34抑制剂在制备防治蒽环类药物诱导心脏毒性的药物中的应用

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