CA3110779A1 - Compositions pharmaceutiques et procedes pour le traitement de la thrombose et l'administration par des dispositifs medicaux - Google Patents
Compositions pharmaceutiques et procedes pour le traitement de la thrombose et l'administration par des dispositifs medicaux Download PDFInfo
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- CA3110779A1 CA3110779A1 CA3110779A CA3110779A CA3110779A1 CA 3110779 A1 CA3110779 A1 CA 3110779A1 CA 3110779 A CA3110779 A CA 3110779A CA 3110779 A CA3110779 A CA 3110779A CA 3110779 A1 CA3110779 A1 CA 3110779A1
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- thrombus
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- 230000007704 transition Effects 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 229960000281 trometamol Drugs 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 150000003673 urethanes Chemical class 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
- 229960005044 vorapaxar Drugs 0.000 description 1
- ZBGXUVOIWDMMJE-QHNZEKIYSA-N vorapaxar Chemical compound C(/[C@@H]1[C@H]2[C@H](C(O[C@@H]2C)=O)C[C@H]2[C@H]1CC[C@H](C2)NC(=O)OCC)=C\C(N=C1)=CC=C1C1=CC=CC(F)=C1 ZBGXUVOIWDMMJE-QHNZEKIYSA-N 0.000 description 1
- NQRYCIGCIAWEIC-CKLVGUEFSA-N vorapaxar sulfate Chemical compound OS(O)(=O)=O.C(/[C@@H]1[C@H]2[C@H](C(O[C@@H]2C)=O)C[C@H]2[C@H]1CC[C@H](C2)NC(=O)OCC)=C\C(N=C1)=CC=C1C1=CC=CC(F)=C1 NQRYCIGCIAWEIC-CKLVGUEFSA-N 0.000 description 1
- 229940087881 zontivity Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4806—Hydrolases (3) acting on peptide bonds (3.4) from animals other than mammals, e.g. snakes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21001—Chymotrypsin (3.4.21.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21004—Trypsin (3.4.21.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/12036—Type of occlusion partial occlusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/1204—Type of occlusion temporary occlusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12136—Balloons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1052—Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Surgical Instruments (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Materials For Medical Uses (AREA)
Abstract
L'invention concerne une composition pharmaceutique et un procédé d'utilisation de la composition pharmaceutique pour le traitement de la thrombose. La composition pharmaceutique peut comprendre un mélange d'enzymes protéolytiques, et éventuellement des composés supplémentaires. La composition pharmaceutique peut comprendre un composé antiagrégant ou anti-thrombotique, tel que Lisini racemici acetylsalicylase. Le procédé peut comprendre l'administration de la composition pharmaceutique à un patient en ayant besoin, comprenant l'administration de la composition pharmaceutique à un thrombus jusqu'à dissolution du thrombus. Le procédé peut également comprendre l'administration d'un ou plusieurs cathéters à ballonnet au patient.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862691319P | 2018-06-28 | 2018-06-28 | |
| US62/691,319 | 2018-06-28 | ||
| PCT/US2019/039878 WO2020006444A1 (fr) | 2018-06-28 | 2019-06-28 | Compositions pharmaceutiques et procédés pour le traitement de la thrombose et l'administration par des dispositifs médicaux |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3110779A1 true CA3110779A1 (fr) | 2020-01-02 |
Family
ID=68985200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3110779A Pending CA3110779A1 (fr) | 2018-06-28 | 2019-06-28 | Compositions pharmaceutiques et procedes pour le traitement de la thrombose et l'administration par des dispositifs medicaux |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP3813687A4 (fr) |
| JP (1) | JP2022525713A (fr) |
| CN (1) | CN112638289A (fr) |
| AU (1) | AU2019292557A1 (fr) |
| BR (1) | BR112021004809A2 (fr) |
| CA (1) | CA3110779A1 (fr) |
| CR (1) | CR20210059A (fr) |
| EA (1) | EA202190494A1 (fr) |
| PE (1) | PE20241469A1 (fr) |
| WO (1) | WO2020006444A1 (fr) |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6130527A (ja) * | 1984-07-20 | 1986-02-12 | Kao Corp | 血栓溶解剤 |
| WO1995033471A1 (fr) * | 1994-06-07 | 1995-12-14 | Hellgren, Lars | Thrombolyse intravasculaire |
| US6022309A (en) * | 1996-04-24 | 2000-02-08 | The Regents Of The University Of California | Opto-acoustic thrombolysis |
| FR2797768B1 (fr) * | 1999-09-01 | 2003-06-13 | Ifremer | Utilisation d'un polysaccharide sulfate de bas poids moleculaire pour l'obtention d'un medicament actif contre la thrombose vasculaire |
| CN1516592A (zh) * | 2001-06-18 | 2004-07-28 | �����Ǽ���&������Դ����˾ | 用于预防和/或治疗心血管疾病、关节炎、皮肤癌、糖尿病、经前综合症和透皮转运的磷虾和/或海产提取物 |
| CA2462512C (fr) * | 2001-10-01 | 2013-11-05 | Bradley H. Strauss | Utilisation de collagenase pour faciliter le croisement de fil-guide dans des occlusions arterielles totales |
| CN1210036C (zh) * | 2002-06-18 | 2005-07-13 | 蚌埠丰原医药科技发展有限公司 | 赖氨匹林的新用途 |
| SE0303588D0 (sv) * | 2003-12-30 | 2003-12-30 | Bioactive Polymers Ab C O Lund | Surface protection of exposed biological tissues |
| JP4677557B2 (ja) * | 2005-05-11 | 2011-04-27 | 国立大学法人東北大学 | 超音波プローブ及びそれを用いたカテーテル並びにその製造方法 |
| EP1726301A1 (fr) * | 2005-05-24 | 2006-11-29 | Flamel Technologies | Composition pharmaceutique pour le traitement de maladies transmises par COX-2 |
| DE102005042338B4 (de) * | 2005-09-06 | 2007-07-05 | Siemens Ag | Kathetereinrichtung |
| WO2007080515A1 (fr) * | 2006-01-13 | 2007-07-19 | Aker Biomarine Asa | Extrait de krill prevenant la thrombose |
| EP2663335A1 (fr) * | 2011-01-13 | 2013-11-20 | Medestea Internazionale S.p.A. | Composition pour régénérer des tissus atrophiques |
| WO2015074036A2 (fr) * | 2013-11-18 | 2015-05-21 | Jeremy Stigall | Procédés et dispositifs de dispersion de thrombus |
| DE202015002060U1 (de) * | 2015-03-17 | 2015-11-25 | Gerhard-Friedrich Horak | Infusions- und Aspirations- Catheter (IAC) (Katheter zur Entfernung von Thromben und Applikation von Medikamenten) |
| CN110177527B (zh) * | 2016-08-12 | 2022-02-01 | 科尼尔赛德生物医学公司 | 用于调节药剂递送用针的插入深度的装置和方法 |
| EP3554611A1 (fr) * | 2016-12-13 | 2019-10-23 | Boston Scientific Scimed Inc. | Système de cathéter pour thrombolyse |
-
2019
- 2019-06-28 CA CA3110779A patent/CA3110779A1/fr active Pending
- 2019-06-28 JP JP2021517700A patent/JP2022525713A/ja active Pending
- 2019-06-28 WO PCT/US2019/039878 patent/WO2020006444A1/fr not_active Ceased
- 2019-06-28 BR BR112021004809-0A patent/BR112021004809A2/pt not_active Application Discontinuation
- 2019-06-28 AU AU2019292557A patent/AU2019292557A1/en not_active Abandoned
- 2019-06-28 CR CR20210059A patent/CR20210059A/es unknown
- 2019-06-28 EP EP19824845.2A patent/EP3813687A4/fr not_active Withdrawn
- 2019-06-28 CN CN201980057015.2A patent/CN112638289A/zh active Pending
- 2019-06-28 EA EA202190494A patent/EA202190494A1/ru unknown
-
2021
- 2021-04-06 PE PE2021000451A patent/PE20241469A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR112021004809A2 (pt) | 2021-06-22 |
| WO2020006444A1 (fr) | 2020-01-02 |
| EP3813687A4 (fr) | 2022-03-23 |
| EA202190494A1 (ru) | 2021-12-09 |
| JP2022525713A (ja) | 2022-05-19 |
| CR20210059A (es) | 2021-12-23 |
| EP3813687A1 (fr) | 2021-05-05 |
| PE20241469A1 (es) | 2024-07-15 |
| CN112638289A (zh) | 2021-04-09 |
| AU2019292557A1 (en) | 2021-04-01 |
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