CA3172981A1 - Methode de traitement de troubles neurologiques a l'aide d'un entrainement de voie synaptique - Google Patents
Methode de traitement de troubles neurologiques a l'aide d'un entrainement de voie synaptique Download PDFInfo
- Publication number
- CA3172981A1 CA3172981A1 CA3172981A CA3172981A CA3172981A1 CA 3172981 A1 CA3172981 A1 CA 3172981A1 CA 3172981 A CA3172981 A CA 3172981A CA 3172981 A CA3172981 A CA 3172981A CA 3172981 A1 CA3172981 A1 CA 3172981A1
- Authority
- CA
- Canada
- Prior art keywords
- synaptic
- pathway
- brain
- depression
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract 15
- 230000000946 synaptic effect Effects 0.000 title claims abstract 15
- 230000037361 pathway Effects 0.000 title claims abstract 13
- 208000012902 Nervous system disease Diseases 0.000 title 1
- 208000025966 Neurological disease Diseases 0.000 title 1
- 210000004556 brain Anatomy 0.000 claims abstract 6
- 230000003213 activating effect Effects 0.000 claims abstract 4
- 239000002831 pharmacologic agent Substances 0.000 claims abstract 4
- 230000004936 stimulating effect Effects 0.000 claims abstract 4
- 208000028173 post-traumatic stress disease Diseases 0.000 claims abstract 3
- 230000001149 cognitive effect Effects 0.000 claims abstract 2
- 230000000926 neurological effect Effects 0.000 claims 2
- 238000011457 non-pharmacological treatment Methods 0.000 claims 2
- 208000007848 Alcoholism Diseases 0.000 claims 1
- 208000020925 Bipolar disease Diseases 0.000 claims 1
- 201000007930 alcohol dependence Diseases 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000003400 hallucinatory effect Effects 0.000 claims 1
- 230000002349 favourable effect Effects 0.000 abstract 2
- YQEZLKZALYSWHR-UHFFFAOYSA-N Ketamine Chemical compound C=1C=CC=C(Cl)C=1C1(NC)CCCCC1=O YQEZLKZALYSWHR-UHFFFAOYSA-N 0.000 abstract 1
- 206010026749 Mania Diseases 0.000 abstract 1
- 229960003299 ketamine Drugs 0.000 abstract 1
- 230000001953 sensory effect Effects 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36025—External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Radiology & Medical Imaging (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Social Psychology (AREA)
- Developmental Disabilities (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
Sont divulguées des méthodes de traitement de la dépression, de la manie, du trouble du stress post-traumatique (PTSD) et de diverses autres affections neurologiques au moyen d'un entraînement de voie synaptique. Les méthodes d'entraînement de voie synaptique comprennent, en général, l'obtention d'un résultat de traitement favorable par activation d'une voie synaptique à l'aide d'un agent pharmacologique, tel que le traitement de symptômes réfractaires de la dépression par la kétamine, suite à la potentialisation du résultat favorable par stimulation répétée de la voie activée. La stimulation d'une voie synaptique peut être obtenue par des moyens intrinsèques, tels que l'activation de la fonction cognitive exercée, ou des moyens extrinsèques, tels que l'administration d'un stimulus sensoriel au patient, la mise en place d'une différence de tension potentielle à travers le cerveau ou une région cérébrale, ou en plaçant le cerveau ou une région cérébrale dans un champ magnétique.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16/827,546 | 2020-03-23 | ||
| US16/827,546 US20200222656A1 (en) | 2016-10-18 | 2020-03-23 | Method for treatment of depression using synaptic pathway training |
| PCT/US2021/022517 WO2021194796A1 (fr) | 2020-03-23 | 2021-03-16 | Méthode de traitement de troubles neurologiques à l'aide d'un entraînement de voie synaptique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3172981A1 true CA3172981A1 (fr) | 2021-09-30 |
Family
ID=77890584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3172981A Pending CA3172981A1 (fr) | 2020-03-23 | 2021-03-16 | Methode de traitement de troubles neurologiques a l'aide d'un entrainement de voie synaptique |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP4126199A4 (fr) |
| BR (1) | BR112022019234A2 (fr) |
| CA (1) | CA3172981A1 (fr) |
| IL (1) | IL296693A (fr) |
| MX (1) | MX2022011862A (fr) |
| WO (1) | WO2021194796A1 (fr) |
| ZA (1) | ZA202210356B (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4486448A1 (fr) | 2022-03-04 | 2025-01-08 | Reset Pharmaceuticals, Inc. | Co-cristaux ou sels comprenant de la psilocine |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9064036B2 (en) * | 2008-04-24 | 2015-06-23 | The Invention Science Fund I, Llc | Methods and systems for monitoring bioactive agent use |
| US20160005320A1 (en) * | 2014-07-02 | 2016-01-07 | Christopher deCharms | Technologies for brain exercise training |
| WO2016061320A2 (fr) * | 2014-10-15 | 2016-04-21 | Rowan University | Thérapie timber pour le trouble du stress post-traumatique |
| AU2017250086A1 (en) * | 2016-04-11 | 2018-09-20 | Clexio Biosciences Ltd. | Deuterated ketamine derivatives |
| US20200222656A1 (en) * | 2016-10-18 | 2020-07-16 | Joseph Rustick | Method for treatment of depression using synaptic pathway training |
| US10596378B2 (en) * | 2016-10-18 | 2020-03-24 | Joseph Rustick | Method for treatment of depression using synaptic pathway training |
| JP2021523228A (ja) * | 2018-05-04 | 2021-09-02 | パーセプション ニューロサイエンス，インコーポレイティド | 物質乱用の治療方法 |
-
2021
- 2021-03-16 IL IL296693A patent/IL296693A/en unknown
- 2021-03-16 BR BR112022019234A patent/BR112022019234A2/pt unknown
- 2021-03-16 WO PCT/US2021/022517 patent/WO2021194796A1/fr not_active Ceased
- 2021-03-16 MX MX2022011862A patent/MX2022011862A/es unknown
- 2021-03-16 CA CA3172981A patent/CA3172981A1/fr active Pending
- 2021-03-16 EP EP21776197.2A patent/EP4126199A4/fr active Pending
-
2022
- 2022-09-19 ZA ZA2022/10356A patent/ZA202210356B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA202210356B (en) | 2023-02-22 |
| IL296693A (en) | 2022-11-01 |
| EP4126199A4 (fr) | 2024-04-10 |
| EP4126199A1 (fr) | 2023-02-08 |
| WO2021194796A1 (fr) | 2021-09-30 |
| BR112022019234A2 (pt) | 2022-11-08 |
| MX2022011862A (es) | 2023-02-16 |
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