CA3171235A1 - Traitement d'une infection a coronavirus et d'une toxicite liee a cytokine - Google Patents
Traitement d'une infection a coronavirus et d'une toxicite liee a cytokine Download PDFInfo
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- CA3171235A1 CA3171235A1 CA3171235A CA3171235A CA3171235A1 CA 3171235 A1 CA3171235 A1 CA 3171235A1 CA 3171235 A CA3171235 A CA 3171235A CA 3171235 A CA3171235 A CA 3171235A CA 3171235 A1 CA3171235 A1 CA 3171235A1
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Public Health (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La présente invention concerne de nouveaux procédés comprenant l'administration de polysulfate de pentosane pour traiter ou prévenir une infection à coronavirus et une toxicité liée à cytokine, y compris la toxicité liée à cytokine résultant de l'activation aberrante du système immunitaire dans une maladie ou une infection à coronavirus, telle que celles liées à SARS-CoV-2.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2020900751 | 2020-03-12 | ||
| AU2020900751A AU2020900751A0 (en) | 2020-03-12 | Treatment for coronavirus infection and associated cytokine toxicity | |
| AU2020904824A AU2020904824A0 (en) | 2020-12-23 | Treatment for Coronavirus infection and associated cytokine toxicity (2) | |
| AU2020904824 | 2020-12-23 | ||
| PCT/AU2021/050215 WO2021179047A1 (fr) | 2020-03-12 | 2021-03-12 | Traitement d'une infection à coronavirus et d'une toxicité liée à cytokine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3171235A1 true CA3171235A1 (fr) | 2021-09-16 |
Family
ID=77670421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3171235A Pending CA3171235A1 (fr) | 2020-03-12 | 2021-03-12 | Traitement d'une infection a coronavirus et d'une toxicite liee a cytokine |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US12268707B2 (fr) |
| EP (1) | EP4117683A4 (fr) |
| JP (1) | JP2023517239A (fr) |
| KR (1) | KR20220159397A (fr) |
| CN (1) | CN115484964B (fr) |
| AU (2) | AU2021234945B2 (fr) |
| BR (1) | BR112022018200A2 (fr) |
| CA (1) | CA3171235A1 (fr) |
| CL (1) | CL2022002457A1 (fr) |
| PH (1) | PH12022552298A1 (fr) |
| WO (1) | WO2021179047A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3171235A1 (fr) | 2020-03-12 | 2021-09-16 | Sydney David Cullis-Hill | Traitement d'une infection a coronavirus et d'une toxicite liee a cytokine |
| FR3144752A1 (fr) * | 2023-01-10 | 2024-07-12 | Song Huang | Utilisation de polysulfate de pentosane pour le traitement de la toux seche |
| WO2024192151A2 (fr) * | 2023-03-13 | 2024-09-19 | Altesa BioSciences, Inc. | Procédé de dosage de vapendavir pour traiter des infections à entérovirus |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2689848A (en) | 1951-02-06 | 1954-09-21 | Wander Ag Dr A | Salts of sulfuric acid esters of xylan |
| CA1327354C (fr) * | 1987-03-19 | 1994-03-01 | David Cullis-Hill | Composes et compositions anti-inflamatoires |
| WO1994011006A1 (fr) | 1992-11-10 | 1994-05-26 | Yeda Research And Development Co. Ltd. | Compositions utilisees dans la regulation de l'activite de la cytokine |
| DE69621528T2 (de) | 1995-02-07 | 2003-01-16 | Shiseido Co. Ltd., Tokio/Tokyo | Anti-inflamatorische agenzien |
| US20050004071A1 (en) | 2003-04-21 | 2005-01-06 | Comper Wayne D. | Charged polysaccharides resistant to lysosomal degradation during kidney filtration and renal passage and their use to treat or prevent infection by coronaviruses |
| US20080004236A1 (en) * | 2004-02-06 | 2008-01-03 | Comper Wayne D | High Dose, Short Interval Use of Sulfated Polysaccharides for Treatment of Infections |
| US20100160253A1 (en) * | 2007-05-31 | 2010-06-24 | Glycan Biosciences | Sulphated xylans for treatment or prophylaxis of respiratory diseases |
| PL2178533T3 (pl) | 2007-08-24 | 2013-08-30 | Marinomed Biotechnologie Gmbh | Kompozycja przeciwwirusowa zawierająca siarczanowany polisacharyd: jota-karagen |
| IT1397247B1 (it) | 2009-05-14 | 2013-01-04 | Fidia Farmaceutici | Nuovi agenti regolatori dell'attivita' citochinica |
| EP2721151B1 (fr) * | 2011-06-20 | 2017-12-06 | Mount Sinai School Of Medicine | Thérapie anti-tnf contre les mucopolysaccharidoses et d'autres maladies lysosomiales |
| JO3529B1 (ar) * | 2013-02-08 | 2020-07-05 | Amgen Res Munich Gmbh | مضاد التصاق خلايا الدم البيض من أجل التخفيف من الاثار السلبية الممكنة الناتجة عن مجالات ارتباط cd3- المحدد |
| JO3701B1 (ar) * | 2014-05-23 | 2021-01-31 | Regeneron Pharma | مضادات حيوية بشرية لمتلازمة الشرق الأوسط التنفسية - بروتين كورونا فيروس الشوكي |
| US10660914B2 (en) | 2015-07-14 | 2020-05-26 | Marinomed Biotech Ag | Stuffy nose deblocking composition having antiviral activity |
| GB201800274D0 (en) * | 2018-01-08 | 2018-02-21 | Enzymatica Ab | Novel treatments |
| CA3171235A1 (fr) | 2020-03-12 | 2021-09-16 | Sydney David Cullis-Hill | Traitement d'une infection a coronavirus et d'une toxicite liee a cytokine |
| CA3179716A1 (fr) * | 2020-04-09 | 2021-10-14 | Paradigm Biopharmaceuticals Ltd | Traitement du syndrome de detresse respiratoire aigue (sdra) avec des polysaccharides polysulfates |
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2021
- 2021-03-12 CA CA3171235A patent/CA3171235A1/fr active Pending
- 2021-03-12 AU AU2021234945A patent/AU2021234945B2/en active Active
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- 2021-03-12 EP EP21767048.8A patent/EP4117683A4/fr active Pending
- 2021-03-12 CN CN202180031179.5A patent/CN115484964B/zh active Active
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- 2021-03-12 WO PCT/AU2021/050215 patent/WO2021179047A1/fr not_active Ceased
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| Publication number | Publication date |
|---|---|
| AU2021234945A1 (en) | 2022-10-06 |
| EP4117683A1 (fr) | 2023-01-18 |
| US20230120864A1 (en) | 2023-04-20 |
| US12268707B2 (en) | 2025-04-08 |
| EP4117683A4 (fr) | 2024-04-24 |
| AU2025234176A1 (en) | 2025-10-16 |
| PH12022552298A1 (en) | 2023-12-11 |
| BR112022018200A2 (pt) | 2022-11-29 |
| US11938146B2 (en) | 2024-03-26 |
| CN115484964B (zh) | 2024-03-15 |
| CL2022002457A1 (es) | 2023-04-14 |
| CN115484964A (zh) | 2022-12-16 |
| JP2023517239A (ja) | 2023-04-24 |
| US20230201250A1 (en) | 2023-06-29 |
| KR20220159397A (ko) | 2022-12-02 |
| AU2021234945B2 (en) | 2025-06-26 |
| WO2021179047A1 (fr) | 2021-09-16 |
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