CA3160445A1 - Traitement de troubles hepatiques - Google Patents
Traitement de troubles hepatiquesInfo
- Publication number
- CA3160445A1 CA3160445A1 CA3160445A CA3160445A CA3160445A1 CA 3160445 A1 CA3160445 A1 CA 3160445A1 CA 3160445 A CA3160445 A CA 3160445A CA 3160445 A CA3160445 A CA 3160445A CA 3160445 A1 CA3160445 A1 CA 3160445A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- patient
- liver
- formula
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
L'invention concerne des méthodes et des compositions pour le traitement de troubles hépatiques, y compris, sans caractère limitatif la stéatohépatite non alcoolique, des symptômes et des manifestations de celle-ci, chez un patient.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962933277P | 2019-11-08 | 2019-11-08 | |
| US62/933,277 | 2019-11-08 | ||
| US202063004403P | 2020-04-02 | 2020-04-02 | |
| US63/004,403 | 2020-04-02 | ||
| PCT/US2020/059522 WO2021092474A1 (fr) | 2019-11-08 | 2020-11-06 | Traitement de troubles hépatiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3160445A1 true CA3160445A1 (fr) | 2021-05-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3160445A Pending CA3160445A1 (fr) | 2019-11-08 | 2020-11-06 | Traitement de troubles hepatiques |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP4054567A4 (fr) |
| JP (1) | JP2023501386A (fr) |
| KR (1) | KR20220098168A (fr) |
| CN (1) | CN114667142A (fr) |
| AU (1) | AU2020380968A1 (fr) |
| BR (1) | BR112022008639A2 (fr) |
| CA (1) | CA3160445A1 (fr) |
| CL (1) | CL2022001167A1 (fr) |
| IL (1) | IL292459A (fr) |
| MX (1) | MX2022005407A (fr) |
| WO (1) | WO2021092474A1 (fr) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3201466A1 (fr) | 2020-12-14 | 2022-06-23 | Regeneron Pharmaceuticals, Inc. | Methodes de traitement de troubles metaboliques et de maladies cardiovasculaires avec des inhibiteurs de la sous-unite beta e de l'inhibine (inhbe) |
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| TW200906823A (en) * | 2007-07-16 | 2009-02-16 | Lilly Co Eli | Compounds and methods for modulating FXR |
| US20140187633A1 (en) * | 2012-12-31 | 2014-07-03 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis |
| MX2018011813A (es) * | 2016-03-28 | 2019-01-24 | Intercept Pharmaceuticals Inc | Medicina obtenida mediante la combinacion de agonista fxr y arb. |
| WO2018170173A1 (fr) * | 2017-03-15 | 2018-09-20 | Metacrine, Inc. | Agonistes du récepteur farnésoïde x et leurs utilisations |
| WO2019023245A1 (fr) * | 2017-07-25 | 2019-01-31 | Cedars-Sinai Medical Center | Méthodes de traitement de maladies hépatiques |
| SG11202101863YA (en) * | 2018-08-30 | 2021-03-30 | Terns Pharmaceuticals Inc | Treating liver disorders |
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2020
- 2020-11-06 JP JP2022526136A patent/JP2023501386A/ja active Pending
- 2020-11-06 IL IL292459A patent/IL292459A/en unknown
- 2020-11-06 WO PCT/US2020/059522 patent/WO2021092474A1/fr not_active Ceased
- 2020-11-06 KR KR1020227018657A patent/KR20220098168A/ko not_active Withdrawn
- 2020-11-06 BR BR112022008639A patent/BR112022008639A2/pt not_active Application Discontinuation
- 2020-11-06 CA CA3160445A patent/CA3160445A1/fr active Pending
- 2020-11-06 EP EP20886094.0A patent/EP4054567A4/fr not_active Withdrawn
- 2020-11-06 CN CN202080077929.8A patent/CN114667142A/zh active Pending
- 2020-11-06 AU AU2020380968A patent/AU2020380968A1/en active Pending
- 2020-11-06 MX MX2022005407A patent/MX2022005407A/es unknown
-
2022
- 2022-05-04 CL CL2022001167A patent/CL2022001167A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2023501386A (ja) | 2023-01-18 |
| WO2021092474A1 (fr) | 2021-05-14 |
| CN114667142A (zh) | 2022-06-24 |
| KR20220098168A (ko) | 2022-07-11 |
| EP4054567A4 (fr) | 2024-01-10 |
| IL292459A (en) | 2022-06-01 |
| BR112022008639A2 (pt) | 2022-07-19 |
| MX2022005407A (es) | 2022-05-24 |
| CL2022001167A1 (es) | 2023-02-10 |
| AU2020380968A1 (en) | 2022-05-12 |
| EP4054567A1 (fr) | 2022-09-14 |
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