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CA3026708A1 - Mecanismes precis de controle de dose et seringues d'administration de medicament - Google Patents

Mecanismes precis de controle de dose et seringues d'administration de medicament Download PDF

Info

Publication number
CA3026708A1
CA3026708A1 CA3026708A CA3026708A CA3026708A1 CA 3026708 A1 CA3026708 A1 CA 3026708A1 CA 3026708 A CA3026708 A CA 3026708A CA 3026708 A CA3026708 A CA 3026708A CA 3026708 A1 CA3026708 A1 CA 3026708A1
Authority
CA
Canada
Prior art keywords
plunger
housing
screw
thread
pitch
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA3026708A
Other languages
English (en)
Inventor
Nathaniel Ryan YOUNG
Lou Castagna
Gary Richardson
Gautam N. SHETTY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UNL Holdings LLC
Original Assignee
UNL Holdings LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UNL Holdings LLC filed Critical UNL Holdings LLC
Priority claimed from PCT/US2016/033950 external-priority patent/WO2017204787A1/fr
Publication of CA3026708A1 publication Critical patent/CA3026708A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A61M5/31526—Dosing by means of stepwise axial movements, e.g. ratchet mechanisms or detents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
    • A61M2005/3139—Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention décrit un mécanisme de contrôle de dose (510, 610) destiné à une seringue comprenant un montage de filetage de vis de mise en prise entre une surface extérieure d'un piston (514, 614) et un canal s'étendant longitudinalement (520D, 620D) d'un logement (520, 620). Le montage de filetage de vis de mise en prise comprend au moins un segment de filetage (514B, 614B) et un guide de pas (520C, 620C) comprenant un filetage à pas variable. Au moins une partie du canal s'étendant longitudinalement (520D, 620D) du logement (520, 620) comprenant l'un du guide de pas (520C, 620C) et dudit segment de filetage (514B, 614B), et le piston (514, 614) comprend l'autre du guide de pas (520C, 620C) et dudit segment de filetage (514B, 614B). Le piston (514, 614) réside au moins partiellement au sein du logement (520, 620) avec ledit segment de filetage (514B, 614B) en prise avec le guide de pas (520C, 620C). Une seringue d'administration de médicament en dose précise (500, 600) comprend un tel mécanisme de contrôle de dose (510, 610), un cylindre (540, 640), un joint de piston (536, 636), et un ensemble adaptateur de cylindre (450) ayant une extrémité de cylindre (452) et une aiguille (454). La seringue (500, 600) peut être une seringue à remplissage au moment de l'utilisation, une seringue pré-remplie, ou une seringue de sécurité présentant des caractéristiques de sécurité intégrées de rétractation d'aiguille ou de protection d'aiguille, ou une combinaison de ces dernières. Des procédés d'assemblage, de fabrication, et de fonctionnement sont décrits de manière similaire.
CA3026708A 2016-05-24 2016-05-24 Mecanismes precis de controle de dose et seringues d'administration de medicament Abandoned CA3026708A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2016/033950 WO2017204787A1 (fr) 2011-12-08 2016-05-24 Mécanismes précis de contrôle de dose et seringues d'administration de médicament

Publications (1)

Publication Number Publication Date
CA3026708A1 true CA3026708A1 (fr) 2017-11-30

Family

ID=64655303

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3026708A Abandoned CA3026708A1 (fr) 2016-05-24 2016-05-24 Mecanismes precis de controle de dose et seringues d'administration de medicament

Country Status (9)

Country Link
EP (1) EP3463517A1 (fr)
JP (1) JP2019519289A (fr)
KR (1) KR20190013854A (fr)
CN (1) CN109641107A (fr)
AU (1) AU2016408375A1 (fr)
BR (1) BR112018074108A2 (fr)
CA (1) CA3026708A1 (fr)
MX (1) MX2018014363A (fr)
SG (1) SG11201810368PA (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020065010A1 (fr) * 2018-09-28 2020-04-02 Owen Mumford Ltd Seringue de sécurité
WO2024069381A1 (fr) * 2022-09-30 2024-04-04 Janssen Biotech, Inc. Assistance électrique pour un dispositif d'injection manuel et auto-injecteur

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11229745B2 (en) * 2019-05-03 2022-01-25 Carefusion 303, Inc. Syringe with priming indicator
CN118718181A (zh) * 2019-06-05 2024-10-01 里珍纳龙药品有限公司 用于精确剂量递送的装置及方法
GB2584730B (en) * 2019-06-14 2022-04-13 Owen Mumford Ltd Drug delivery device assembly
US12013267B2 (en) * 2019-07-01 2024-06-18 West Pharmaceutical Services, Inc. System and method for measuring fluid flow from a syringe
CA3164799A1 (fr) * 2019-12-18 2021-06-24 Janssen Pharmaceutica Nv Systemes d'emballage pour dispositifs d'administration de medicaments et kits d'emballage
WO2021229606A1 (fr) * 2020-05-15 2021-11-18 Biocon Biologics Limited Dispositif auto-injecteur pour l'administration de médicaments
US12329927B2 (en) * 2020-08-18 2025-06-17 Becton, Dickinson And Company Multiple telescoping screw-driven pump mechanism with anti-rotation of innermost screw keyed to reservoir plunger in fluid delivery device
CN112206069B (zh) * 2020-10-12 2023-06-02 北京天悦生科技有限公司 连续注射器的控制方法、装置及连续注射器
CN118267231A (zh) * 2022-12-30 2024-07-02 沈阳兴齐眼药股份有限公司 给药装置
GB2635378A (en) * 2023-11-10 2025-05-14 North West Anglia Nhs Found Trust Metered dose syringe

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5582598A (en) * 1994-09-19 1996-12-10 Becton Dickinson And Company Medication delivery pen with variable increment dose scale
US5688251A (en) * 1995-09-19 1997-11-18 Becton Dickinson And Company Cartridge loading and priming mechanism for a pen injector
CZ297361B6 (cs) * 1998-01-30 2006-11-15 Novo Nordisk A/S Injekcní stríkacka
EP1877121B1 (fr) * 2005-04-24 2015-09-23 Novo Nordisk A/S Dispositif d'injection
DE102005019428A1 (de) * 2005-04-25 2006-10-26 Tecpharma Licensing Ag Längenausgleich für eine Einstellvorrichtung einer Injektionsvorrichtung
DE102006038103B4 (de) * 2006-08-14 2017-02-23 Tecpharma Licensing Ag Injektionsvorrichtung mit variabler Gewindeführung
CA2742810C (fr) * 2008-11-07 2016-11-29 Min Wei Stylet d'injection pour injection intradermique d'un medicament
DK2788054T3 (en) * 2011-12-08 2018-08-06 Unl Holdings Llc ACCURATE DOSAGE CONTROL MECHANISMS AND SPRAYS FOR ADMINISTRATION OF MEDICINE

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020065010A1 (fr) * 2018-09-28 2020-04-02 Owen Mumford Ltd Seringue de sécurité
CN112930205A (zh) * 2018-09-28 2021-06-08 欧文蒙福德有限公司 安全注射器
WO2024069381A1 (fr) * 2022-09-30 2024-04-04 Janssen Biotech, Inc. Assistance électrique pour un dispositif d'injection manuel et auto-injecteur

Also Published As

Publication number Publication date
CN109641107A (zh) 2019-04-16
SG11201810368PA (en) 2018-12-28
AU2016408375A1 (en) 2019-01-03
JP2019519289A (ja) 2019-07-11
BR112018074108A2 (pt) 2019-03-06
EP3463517A1 (fr) 2019-04-10
MX2018014363A (es) 2019-04-11
KR20190013854A (ko) 2019-02-11

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20220301