[go: up one dir, main page]

CA2879824A1 - Sels de saxagliptine - Google Patents

Sels de saxagliptine Download PDF

Info

Publication number
CA2879824A1
CA2879824A1 CA2879824A CA2879824A CA2879824A1 CA 2879824 A1 CA2879824 A1 CA 2879824A1 CA 2879824 A CA2879824 A CA 2879824A CA 2879824 A CA2879824 A CA 2879824A CA 2879824 A1 CA2879824 A1 CA 2879824A1
Authority
CA
Canada
Prior art keywords
saxagliptin
acetate
process according
bicarbonate
bisulphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2879824A
Other languages
English (en)
Inventor
Ram Chander Aryan
Ashwani Kumar Singh
Amit Sharma
Ramendra Singh Rathore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of CA2879824A1 publication Critical patent/CA2879824A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA2879824A 2012-07-02 2013-07-02 Sels de saxagliptine Abandoned CA2879824A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN2061/DEL/2012 2012-07-02
IN2061DE2012 2012-07-02
IN3917DE2012 2012-12-19
IN3917/DEL/2012 2012-12-19
PCT/IB2013/055429 WO2014006569A2 (fr) 2012-07-02 2013-07-02 Sels de saxagliptine

Publications (1)

Publication Number Publication Date
CA2879824A1 true CA2879824A1 (fr) 2014-01-09

Family

ID=54193750

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2879824A Abandoned CA2879824A1 (fr) 2012-07-02 2013-07-02 Sels de saxagliptine

Country Status (5)

Country Link
EP (1) EP2867206A2 (fr)
AU (1) AU2013285078A1 (fr)
CA (1) CA2879824A1 (fr)
SG (1) SG11201408619WA (fr)
WO (1) WO2014006569A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2690321T3 (es) 2012-05-24 2018-11-20 Apotex Inc. Sales de saxagliptina con ácidos orgánicos
WO2015166466A1 (fr) * 2014-05-01 2015-11-05 Sun Pharmaceutical Industries Limited Forme cristalline d'acétate de saxagliptine

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395767B2 (en) * 2000-03-10 2002-05-28 Bristol-Myers Squibb Company Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
US7420079B2 (en) 2002-12-09 2008-09-02 Bristol-Myers Squibb Company Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof
TW200538122A (en) 2004-03-31 2005-12-01 Bristol Myers Squibb Co Process for preparing a dipeptidyl peptidase Ⅳ inhibitor and intermediates employed therein
US7741082B2 (en) 2004-04-14 2010-06-22 Bristol-Myers Squibb Company Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor
US7214702B2 (en) 2004-05-25 2007-05-08 Bristol-Myers Squibb Company Process for producing a dipeptidyl peptidase IV inhibitor
PE20090696A1 (es) * 2007-04-20 2009-06-20 Bristol Myers Squibb Co Formas cristalinas de saxagliptina y procesos para preparar las mismas
BRPI1006547A2 (pt) 2009-04-09 2016-10-18 Sandoz Ag formas cristalinas, cloridato de saxagliptina, composição farmaceutic, processo para preparação da forma i-s de cloridato e saxagliotina, processo para preparação da forma ht de cloridato de saxagliptina uso de sexagliptina cristalino e uso da forma iv s de cloridato de saxagloptina
WO2012017029A1 (fr) * 2010-08-06 2012-02-09 Sandoz Ag Nouveaux sels de saxagliptine comportant des diacides organiques
EP2601175A1 (fr) 2010-08-06 2013-06-12 Sandoz AG Nouveau composé cristallin comprenant de la saxagliptine et de l'acide phosphorique
US8410288B2 (en) 2010-10-04 2013-04-02 Teva Pharmaceutical Industries Ltd. Polymorphs of Saxagliptin hydrochloride and processes for preparing them
CN102086172A (zh) * 2011-01-13 2011-06-08 廖国超 沙格列汀的药用盐及其制备方法

Also Published As

Publication number Publication date
WO2014006569A2 (fr) 2014-01-09
SG11201408619WA (en) 2015-01-29
WO2014006569A3 (fr) 2014-03-06
AU2013285078A1 (en) 2015-01-29
EP2867206A2 (fr) 2015-05-06

Similar Documents

Publication Publication Date Title
US11753394B2 (en) Synthesis of omecamtiv mecarbil
EP2609099A2 (fr) Sitagliptine, sels et polymorphes de celle-ci
JP2021105003A (ja) 多形体及びキナゾリニル誘導体の調製プロセス
JP2013525384A (ja) ニトロイミダゾール系化合物、その製造方法および用途
US10464906B2 (en) Crystalline forms of a histone deacetylase inhibitor
WO2018142327A1 (fr) Sels d'oxalate de ténéligliptine et solvates de ceux-ci, intermédiaires, procédé de préparation
CA2879824A1 (fr) Sels de saxagliptine
EP2860180A1 (fr) Nouveaux sels gentisate d'inhibiteur de DPP-IV
US20150239909A1 (en) Process for the preparation of (1s,4s,5s)-4-bromo-6-oxabicyclo[3.2.1]octan-7-one
US20130123501A1 (en) Process for the preparation of the compound osi-906
EP1511717A1 (fr) Forme cristalline de nateglinide
CN115515936A (zh) 用于制备(r)-4-(1-(6-(4-(三氟甲基)苄基)-6-氮杂螺[2.5]辛烷-5-甲酰胺基)-环丙基)苯甲酸或其盐的方法
US20150329489A1 (en) Saxagliptin salts
AU2012277403A1 (en) Novel salts of sitagliptin
US20040181089A1 (en) Polymorphic forms of nateglinide
US11434226B2 (en) Salt and polymorph of benzopyrimidinone compound and pharmaceutical composition and use thereof
WO2017213944A1 (fr) Formes solides de ceftolozane et procédés de préparation
EP1467964A1 (fr) Formes polymorphes de nateglinide
WO2015092624A1 (fr) Mono-oxalate de nilotinib et sa forme cristalline
US10793554B2 (en) Solid forms of 4-(2-fluoro-4-(1-methyl-1H-benzo[d]imidazol-5-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone
CN111620875B (zh) 咪唑并吡嗪类化合物的制备工艺
WO2014147641A2 (fr) Sel de phosphate de sitagliptine et de ptérostilbène, son procédé de préparation et composition pharmaceutique en contenant
WO2015166466A1 (fr) Forme cristalline d'acétate de saxagliptine
WO2015114479A1 (fr) Formes cristallines d'oxalate, d'adipate, de succinate, de phosphate, de sulphate, de fumaratetartrate, de nitrate et de borate de darapladib

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20141223

FZDE Dead

Effective date: 20170517