CA2733532A1 - Systeme de traitement pour des compositions de soins buccaux - Google Patents

Systeme de traitement pour des compositions de soins buccaux Download PDF

Info

Publication number: CA2733532A1
Authority: CA; Canada
Prior art keywords: compositions; agents; materials; phosphate; streams
Prior art date: 2008-08-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA2733532A

Other languages

English (en)

Other versions

CA2733532C (fr

Inventor

James Albert Berta

David Scott Howe

David Michael Farren

Steve Paul Miller

Shane Michael De La Harpe

Volker Bernhard Deister

Jeff Timothy Cullinane

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Procter and Gamble Co

Original Assignee

Procter and Gamble Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-08-26

Filing date

2009-08-24

Publication date

2010-03-11

2009-08-24 Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co

2010-03-11 Publication of CA2733532A1 publication Critical patent/CA2733532A1/fr

2013-07-30 Application granted granted Critical

2013-07-30 Publication of CA2733532C publication Critical patent/CA2733532C/fr

Status Expired - Fee Related legal-status Critical Current

2029-08-24 Anticipated expiration legal-status Critical

Links

239000000203 mixture Substances 0.000 title claims abstract description 174
238000012545 processing Methods 0.000 title claims abstract description 17
238000000034 method Methods 0.000 claims abstract description 28
238000004519 manufacturing process Methods 0.000 claims abstract description 26
230000008569 process Effects 0.000 claims abstract description 25
238000002156 mixing Methods 0.000 claims description 35
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 28
238000009472 formulation Methods 0.000 claims description 23
239000000654 additive Substances 0.000 claims description 12
230000000996 additive effect Effects 0.000 claims description 9
238000011049 filling Methods 0.000 claims description 6
238000002347 injection Methods 0.000 claims description 5
239000007924 injection Substances 0.000 claims description 5
238000010924 continuous production Methods 0.000 claims description 2
238000012546 transfer Methods 0.000 claims description 2
239000013011 aqueous formulation Substances 0.000 claims 2
239000000463 material Substances 0.000 abstract description 70
239000000551 dentifrice Substances 0.000 abstract description 29
239000000126 substance Substances 0.000 abstract description 20
239000007788 liquid Substances 0.000 abstract description 19
238000004140 cleaning Methods 0.000 abstract description 14
239000002324 mouth wash Substances 0.000 abstract description 9
239000002699 waste material Substances 0.000 abstract description 4
238000000275 quality assurance Methods 0.000 abstract description 3
230000009467 reduction Effects 0.000 abstract description 3
-1 mouthspray Substances 0.000 description 68
239000003795 chemical substances by application Substances 0.000 description 49
239000000047 product Substances 0.000 description 49
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 48
239000002585 base Substances 0.000 description 38
239000004615 ingredient Substances 0.000 description 38
229910019142 PO4 Inorganic materials 0.000 description 34
235000021317 phosphate Nutrition 0.000 description 33
239000000796 flavoring agent Substances 0.000 description 28
239000010452 phosphate Substances 0.000 description 28
235000019634 flavors Nutrition 0.000 description 27
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 27
239000000377 silicon dioxide Substances 0.000 description 24
XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 description 19
150000003839 salts Chemical class 0.000 description 19
229920000388 Polyphosphate Polymers 0.000 description 17
125000000217 alkyl group Chemical group 0.000 description 17
229920001223 polyethylene glycol Polymers 0.000 description 17
229920000642 polymer Polymers 0.000 description 17
239000001205 polyphosphate Substances 0.000 description 17
235000011176 polyphosphates Nutrition 0.000 description 17
239000004094 surface-active agent Substances 0.000 description 16
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 15
239000003082 abrasive agent Substances 0.000 description 15
239000011734 sodium Substances 0.000 description 15
229910052708 sodium Inorganic materials 0.000 description 15
229940083542 sodium Drugs 0.000 description 14
PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 description 14
NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 13
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 13
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 13
229920001577 copolymer Polymers 0.000 description 13
CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical class C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 13
239000000600 sorbitol Substances 0.000 description 13
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 12
238000003860 storage Methods 0.000 description 12
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 11
230000008901 benefit Effects 0.000 description 11
235000003599 food sweetener Nutrition 0.000 description 11
239000000499 gel Substances 0.000 description 11
235000019204 saccharin Nutrition 0.000 description 11
229940081974 saccharin Drugs 0.000 description 11
239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 11
239000003765 sweetening agent Substances 0.000 description 11
KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 10
GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 10
229910052783 alkali metal Inorganic materials 0.000 description 10
239000002738 chelating agent Substances 0.000 description 10
150000001875 compounds Chemical class 0.000 description 10
239000002826 coolant Substances 0.000 description 10
235000011180 diphosphates Nutrition 0.000 description 10
150000002978 peroxides Chemical class 0.000 description 10
229920002125 Sokalan® Polymers 0.000 description 9
239000004599 antimicrobial Substances 0.000 description 9
125000004432 carbon atom Chemical group C* 0.000 description 9
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 9
235000019820 disodium diphosphate Nutrition 0.000 description 9
230000000694 effects Effects 0.000 description 9
239000000243 solution Substances 0.000 description 9
239000000606 toothpaste Substances 0.000 description 9
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerol Natural products OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 8
239000002253 acid Substances 0.000 description 8
230000009471 action Effects 0.000 description 8
GYQBBRRVRKFJRG-UHFFFAOYSA-L disodium pyrophosphate Chemical compound [Na+].[Na+].OP([O-])(=O)OP(O)([O-])=O GYQBBRRVRKFJRG-UHFFFAOYSA-L 0.000 description 8
229940091249 fluoride supplement Drugs 0.000 description 8
210000000214 mouth Anatomy 0.000 description 8
SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 7
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 7
DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 7
239000003945 anionic surfactant Substances 0.000 description 7
229910052500 inorganic mineral Inorganic materials 0.000 description 7
229910021645 metal ion Inorganic materials 0.000 description 7
235000010755 mineral Nutrition 0.000 description 7
239000011707 mineral Substances 0.000 description 7
229920001983 poloxamer Polymers 0.000 description 7
239000011775 sodium fluoride Substances 0.000 description 7
235000013024 sodium fluoride Nutrition 0.000 description 7
235000019333 sodium laurylsulphate Nutrition 0.000 description 7
MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 6
238000010923 batch production Methods 0.000 description 6
230000027455 binding Effects 0.000 description 6
239000011575 calcium Substances 0.000 description 6
229910052791 calcium Inorganic materials 0.000 description 6
235000001465 calcium Nutrition 0.000 description 6
229960001631 carbomer Drugs 0.000 description 6
239000003086 colorant Substances 0.000 description 6
229940038485 disodium pyrophosphate Drugs 0.000 description 6
230000006870 function Effects 0.000 description 6
239000003906 humectant Substances 0.000 description 6
239000000178 monomer Substances 0.000 description 6
229920001451 polypropylene glycol Polymers 0.000 description 6
239000001488 sodium phosphate Substances 0.000 description 6
230000003068 static effect Effects 0.000 description 6
229940034610 toothpaste Drugs 0.000 description 6
ZTWTYVWXUKTLCP-UHFFFAOYSA-N vinylphosphonic acid Chemical compound OP(O)(=O)C=C ZTWTYVWXUKTLCP-UHFFFAOYSA-N 0.000 description 6
229920001285 xanthan gum Polymers 0.000 description 6
239000000230 xanthan gum Substances 0.000 description 6
235000010493 xanthan gum Nutrition 0.000 description 6
229940082509 xanthan gum Drugs 0.000 description 6
NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 5
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 5
229920002134 Carboxymethyl cellulose Polymers 0.000 description 5
NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 5
IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical compound OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 description 5
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 5
239000013543 active substance Substances 0.000 description 5
150000001340 alkali metals Chemical class 0.000 description 5
125000000129 anionic group Chemical group 0.000 description 5
235000010948 carboxy methyl cellulose Nutrition 0.000 description 5
239000003599 detergent Substances 0.000 description 5
235000019441 ethanol Nutrition 0.000 description 5
239000012467 final product Substances 0.000 description 5
239000012530 fluid Substances 0.000 description 5
FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 description 5
229940041616 menthol Drugs 0.000 description 5
108090000623 proteins and genes Proteins 0.000 description 5
102000004169 proteins and genes Human genes 0.000 description 5
FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 description 5
235000011121 sodium hydroxide Nutrition 0.000 description 5
239000007787 solid Substances 0.000 description 5
229960002799 stannous fluoride Drugs 0.000 description 5
239000004408 titanium dioxide Substances 0.000 description 5
229960003500 triclosan Drugs 0.000 description 5
229910052725 zinc Inorganic materials 0.000 description 5
239000011701 zinc Substances 0.000 description 5
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 4
208000006558 Dental Calculus Diseases 0.000 description 4
IMQLKJBTEOYOSI-UHFFFAOYSA-N Phytic acid Natural products OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O IMQLKJBTEOYOSI-UHFFFAOYSA-N 0.000 description 4
239000002202 Polyethylene glycol Substances 0.000 description 4
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 4
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 4
229930006000 Sucrose Natural products 0.000 description 4
XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 description 4
238000013019 agitation Methods 0.000 description 4
150000003863 ammonium salts Chemical class 0.000 description 4
230000002272 anti-calculus Effects 0.000 description 4
239000010949 copper Substances 0.000 description 4
229910052802 copper Inorganic materials 0.000 description 4
229940008099 dimethicone Drugs 0.000 description 4
239000004205 dimethyl polysiloxane Substances 0.000 description 4
XQRLCLUYWUNEEH-UHFFFAOYSA-L diphosphonate(2-) Chemical group [O-]P(=O)OP([O-])=O XQRLCLUYWUNEEH-UHFFFAOYSA-L 0.000 description 4
239000003995 emulsifying agent Substances 0.000 description 4
238000005516 engineering process Methods 0.000 description 4
235000011187 glycerol Nutrition 0.000 description 4
230000002209 hydrophobic effect Effects 0.000 description 4
150000002500 ions Chemical class 0.000 description 4
230000036961 partial effect Effects 0.000 description 4
239000002245 particle Substances 0.000 description 4
125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 description 4
UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 description 4
150000003013 phosphoric acid derivatives Chemical class 0.000 description 4
235000002949 phytic acid Nutrition 0.000 description 4
229920000435 poly(dimethylsiloxane) Polymers 0.000 description 4
229920000058 polyacrylate Polymers 0.000 description 4
229920005646 polycarboxylate Polymers 0.000 description 4
229960003975 potassium Drugs 0.000 description 4
229910052700 potassium Inorganic materials 0.000 description 4
239000011591 potassium Substances 0.000 description 4
JFINOWIINSTUNY-UHFFFAOYSA-N pyrrolidin-3-ylmethanesulfonamide Chemical compound NS(=O)(=O)CC1CCNC1 JFINOWIINSTUNY-UHFFFAOYSA-N 0.000 description 4
125000001453 quaternary ammonium group Chemical group 0.000 description 4
229940071089 sarcosinate Drugs 0.000 description 4
ANOBYBYXJXCGBS-UHFFFAOYSA-L stannous fluoride Chemical compound F[Sn]F ANOBYBYXJXCGBS-UHFFFAOYSA-L 0.000 description 4
239000005720 sucrose Substances 0.000 description 4
MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 description 4
229910000406 trisodium phosphate Inorganic materials 0.000 description 4
OVSKIKFHRZPJSS-UHFFFAOYSA-N 2,4-D Chemical compound OC(=O)COC1=CC=C(Cl)C=C1Cl OVSKIKFHRZPJSS-UHFFFAOYSA-N 0.000 description 3
QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 3
QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 3
KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 3
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 3
KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 3
JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 description 3
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
VUNOFAIHSALQQH-UHFFFAOYSA-N Ethyl menthane carboxamide Chemical compound CCNC(=O)C1CC(C)CCC1C(C)C VUNOFAIHSALQQH-UHFFFAOYSA-N 0.000 description 3
WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 3
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 3
UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 3
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 3
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 3
125000003342 alkenyl group Chemical group 0.000 description 3
229920006318 anionic polymer Polymers 0.000 description 3
229940027983 antiseptic and disinfectant quaternary ammonium compound Drugs 0.000 description 3
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 3
229960003237 betaine Drugs 0.000 description 3
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239000012876 carrier material Substances 0.000 description 3
125000002091 cationic group Chemical group 0.000 description 3
YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 description 3
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239000007795 chemical reaction product Substances 0.000 description 3
235000015165 citric acid Nutrition 0.000 description 3
238000000576 coating method Methods 0.000 description 3
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229910001431 copper ion Inorganic materials 0.000 description 3
239000011162 core material Substances 0.000 description 3
208000002925 dental caries Diseases 0.000 description 3
NBIIXXVUZAFLBC-UHFFFAOYSA-M dihydrogenphosphate Chemical compound OP(O)([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-M 0.000 description 3
235000013870 dimethyl polysiloxane Nutrition 0.000 description 3
238000004851 dishwashing Methods 0.000 description 3
239000004744 fabric Substances 0.000 description 3
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229960002737 fructose Drugs 0.000 description 3
UPBDXRPQPOWRKR-UHFFFAOYSA-N furan-2,5-dione;methoxyethene Chemical compound COC=C.O=C1OC(=O)C=C1 UPBDXRPQPOWRKR-UHFFFAOYSA-N 0.000 description 3
208000007565 gingivitis Diseases 0.000 description 3
230000036541 health Effects 0.000 description 3
238000011086 high cleaning Methods 0.000 description 3
CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 3
229960000367 inositol Drugs 0.000 description 3
ZYTMANIQRDEHIO-KXUCPTDWSA-N isopulegol Chemical compound C[C@@H]1CC[C@@H](C(C)=C)[C@H](O)C1 ZYTMANIQRDEHIO-KXUCPTDWSA-N 0.000 description 3
150000002688 maleic acid derivatives Chemical class 0.000 description 3
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 3
OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 description 3
244000005700 microbiome Species 0.000 description 3
230000004048 modification Effects 0.000 description 3
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239000002736 nonionic surfactant Substances 0.000 description 3
239000003921 oil Substances 0.000 description 3
235000019198 oils Nutrition 0.000 description 3
239000006072 paste Substances 0.000 description 3
229940068041 phytic acid Drugs 0.000 description 3
239000000467 phytic acid Substances 0.000 description 3
SATCULPHIDQDRE-UHFFFAOYSA-N piperonal Chemical compound O=CC1=CC=C2OCOC2=C1 SATCULPHIDQDRE-UHFFFAOYSA-N 0.000 description 3
238000005498 polishing Methods 0.000 description 3
238000002360 preparation method Methods 0.000 description 3
230000002265 prevention Effects 0.000 description 3
150000003856 quaternary ammonium compounds Chemical class 0.000 description 3
239000002994 raw material Substances 0.000 description 3
CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 3
235000019818 tetrasodium diphosphate Nutrition 0.000 description 3
239000002562 thickening agent Substances 0.000 description 3
RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 3
235000019801 trisodium phosphate Nutrition 0.000 description 3
AQLJVWUFPCUVLO-UHFFFAOYSA-N urea hydrogen peroxide Chemical compound OO.NC(N)=O AQLJVWUFPCUVLO-UHFFFAOYSA-N 0.000 description 3
238000010792 warming Methods 0.000 description 3
230000002087 whitening effect Effects 0.000 description 3
NFLGAXVYCFJBMK-RKDXNWHRSA-N (+)-isomenthone Natural products CC(C)[C@H]1CC[C@@H](C)CC1=O NFLGAXVYCFJBMK-RKDXNWHRSA-N 0.000 description 2
XHXUANMFYXWVNG-ADEWGFFLSA-N (-)-Menthyl acetate Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(C)=O XHXUANMFYXWVNG-ADEWGFFLSA-N 0.000 description 2
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239000011118 polyvinyl acetate Substances 0.000 description 1
229920002451 polyvinyl alcohol Polymers 0.000 description 1
AVTYONGGKAJVTE-OLXYHTOASA-L potassium L-tartrate Chemical compound [K+].[K+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O AVTYONGGKAJVTE-OLXYHTOASA-L 0.000 description 1
XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
KYKNRZGSIGMXFH-ZVGUSBNCSA-M potassium bitartrate Chemical compound [K+].OC(=O)[C@H](O)[C@@H](O)C([O-])=O KYKNRZGSIGMXFH-ZVGUSBNCSA-M 0.000 description 1
239000011698 potassium fluoride Substances 0.000 description 1
235000003270 potassium fluoride Nutrition 0.000 description 1
239000004224 potassium gluconate Substances 0.000 description 1
235000013926 potassium gluconate Nutrition 0.000 description 1
229960003189 potassium gluconate Drugs 0.000 description 1
229940086065 potassium hydrogentartrate Drugs 0.000 description 1
235000019828 potassium polyphosphate Nutrition 0.000 description 1
159000000001 potassium salts Chemical class 0.000 description 1
LJCNRYVRMXRIQR-OLXYHTOASA-L potassium sodium L-tartrate Chemical compound [Na+].[K+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O LJCNRYVRMXRIQR-OLXYHTOASA-L 0.000 description 1
239000001472 potassium tartrate Substances 0.000 description 1
239000000843 powder Substances 0.000 description 1
239000002244 precipitate Substances 0.000 description 1
230000003449 preventive effect Effects 0.000 description 1
230000001737 promoting effect Effects 0.000 description 1
KCXFHTAICRTXLI-UHFFFAOYSA-N propane-1-sulfonic acid Chemical compound CCCS(O)(=O)=O KCXFHTAICRTXLI-UHFFFAOYSA-N 0.000 description 1
238000011321 prophylaxis Methods 0.000 description 1
230000009257 reactivity Effects 0.000 description 1
230000003134 recirculating effect Effects 0.000 description 1
230000000306 recurrent effect Effects 0.000 description 1
238000006479 redox reaction Methods 0.000 description 1
238000007670 refining Methods 0.000 description 1
230000001105 regulatory effect Effects 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
235000002020 sage Nutrition 0.000 description 1
108700004121 sarkosyl Proteins 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
230000035945 sensitivity Effects 0.000 description 1
239000003352 sequestering agent Substances 0.000 description 1
238000004904 shortening Methods 0.000 description 1
239000002002 slurry Substances 0.000 description 1
239000000344 soap Substances 0.000 description 1
HELHAJAZNSDZJO-OLXYHTOASA-L sodium L-tartrate Chemical compound [Na+].[Na+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O HELHAJAZNSDZJO-OLXYHTOASA-L 0.000 description 1
235000017557 sodium bicarbonate Nutrition 0.000 description 1
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
239000001509 sodium citrate Substances 0.000 description 1
NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
235000011083 sodium citrates Nutrition 0.000 description 1
AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 description 1
235000012207 sodium gluconate Nutrition 0.000 description 1
229940048106 sodium lauroyl isethionate Drugs 0.000 description 1
KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 description 1
229940045885 sodium lauroyl sarcosinate Drugs 0.000 description 1
229940075560 sodium lauryl sulfoacetate Drugs 0.000 description 1
229960004711 sodium monofluorophosphate Drugs 0.000 description 1
229940045872 sodium percarbonate Drugs 0.000 description 1
PFUVRDFDKPNGAV-UHFFFAOYSA-N sodium peroxide Chemical compound [Na+].[Na+].[O-][O-] PFUVRDFDKPNGAV-UHFFFAOYSA-N 0.000 description 1
229940045919 sodium polymetaphosphate Drugs 0.000 description 1
235000019830 sodium polyphosphate Nutrition 0.000 description 1
239000001476 sodium potassium tartrate Substances 0.000 description 1
235000011006 sodium potassium tartrate Nutrition 0.000 description 1
239000001433 sodium tartrate Substances 0.000 description 1
NKAAEMMYHLFEFN-ZVGUSBNCSA-M sodium;(2r,3r)-2,3,4-trihydroxy-4-oxobutanoate Chemical compound [Na+].OC(=O)[C@H](O)[C@@H](O)C([O-])=O NKAAEMMYHLFEFN-ZVGUSBNCSA-M 0.000 description 1
BRMSVEGRHOZCAM-UHFFFAOYSA-M sodium;2-dodecanoyloxyethanesulfonate Chemical compound [Na+].CCCCCCCCCCCC(=O)OCCS([O-])(=O)=O BRMSVEGRHOZCAM-UHFFFAOYSA-M 0.000 description 1
UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 description 1
MWNQXXOSWHCCOZ-UHFFFAOYSA-L sodium;oxido carbonate Chemical compound [Na+].[O-]OC([O-])=O MWNQXXOSWHCCOZ-UHFFFAOYSA-L 0.000 description 1
239000002904 solvent Substances 0.000 description 1
235000019721 spearmint oil Nutrition 0.000 description 1
238000009987 spinning Methods 0.000 description 1
239000007921 spray Substances 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
239000001119 stannous chloride Substances 0.000 description 1
235000011150 stannous chloride Nutrition 0.000 description 1
229940007163 stannous tartrate Drugs 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
235000019202 steviosides Nutrition 0.000 description 1
238000003756 stirring Methods 0.000 description 1
229910052712 strontium Inorganic materials 0.000 description 1
CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
235000019408 sucralose Nutrition 0.000 description 1
BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 description 1
150000005846 sugar alcohols Polymers 0.000 description 1
DIORMHZUUKOISG-UHFFFAOYSA-N sulfoformic acid Chemical compound OC(=O)S(O)(=O)=O DIORMHZUUKOISG-UHFFFAOYSA-N 0.000 description 1
150000003462 sulfoxides Chemical class 0.000 description 1
238000001356 surgical procedure Methods 0.000 description 1
239000000725 suspension Substances 0.000 description 1
239000006188 syrup Substances 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
238000007910 systemic administration Methods 0.000 description 1
239000003826 tablet Substances 0.000 description 1
239000007916 tablet composition Substances 0.000 description 1
239000011975 tartaric acid Substances 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
229940095064 tartrate Drugs 0.000 description 1
229940104261 taurate Drugs 0.000 description 1
XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 1
150000003512 tertiary amines Chemical class 0.000 description 1
229940124597 therapeutic agent Drugs 0.000 description 1
229910052718 tin Inorganic materials 0.000 description 1
IUTCEZPPWBHGIX-UHFFFAOYSA-N tin(2+) Chemical compound [Sn+2] IUTCEZPPWBHGIX-UHFFFAOYSA-N 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
VVGOCOMZRGWHPI-UHFFFAOYSA-N trans-hept-4-enal Natural products CCC=CCCC=O VVGOCOMZRGWHPI-UHFFFAOYSA-N 0.000 description 1
XMLSXPIVAXONDL-UHFFFAOYSA-N trans-jasmone Natural products CCC=CCC1=C(C)CCC1=O XMLSXPIVAXONDL-UHFFFAOYSA-N 0.000 description 1
230000000472 traumatic effect Effects 0.000 description 1
238000011282 treatment Methods 0.000 description 1
229940078499 tricalcium phosphate Drugs 0.000 description 1
229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
235000019731 tricalcium phosphate Nutrition 0.000 description 1
150000005691 triesters Chemical class 0.000 description 1
229940072029 trilaureth-4 phosphate Drugs 0.000 description 1
241001148471 unidentified anaerobic bacterium Species 0.000 description 1
238000011144 upstream manufacturing Methods 0.000 description 1
150000003672 ureas Chemical class 0.000 description 1
229920003169 water-soluble polymer Polymers 0.000 description 1
239000009637 wintergreen oil Substances 0.000 description 1
239000011667 zinc carbonate Substances 0.000 description 1
235000004416 zinc carbonate Nutrition 0.000 description 1
229910000010 zinc carbonate Inorganic materials 0.000 description 1
239000011592 zinc chloride Substances 0.000 description 1
235000005074 zinc chloride Nutrition 0.000 description 1
229960001939 zinc chloride Drugs 0.000 description 1
239000011670 zinc gluconate Substances 0.000 description 1
235000011478 zinc gluconate Nutrition 0.000 description 1
229960000306 zinc gluconate Drugs 0.000 description 1
239000011787 zinc oxide Substances 0.000 description 1
229960001296 zinc oxide Drugs 0.000 description 1
229940105296 zinc peroxide Drugs 0.000 description 1
LRXTYHSAJDENHV-UHFFFAOYSA-H zinc phosphate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O LRXTYHSAJDENHV-UHFFFAOYSA-H 0.000 description 1
229910000165 zinc phosphate Inorganic materials 0.000 description 1
NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
229960001763 zinc sulfate Drugs 0.000 description 1
229910000368 zinc sulfate Inorganic materials 0.000 description 1
VRGNUPCISFMPEM-ZVGUSBNCSA-L zinc;(2r,3r)-2,3-dihydroxybutanedioate Chemical compound [Zn+2].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O VRGNUPCISFMPEM-ZVGUSBNCSA-L 0.000 description 1
UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
HZUKVFGMACOUEH-UHFFFAOYSA-L zinc;2-hydroxypropanoate;dihydrate Chemical compound O.O.[Zn+2].CC(O)C([O-])=O.CC(O)C([O-])=O HZUKVFGMACOUEH-UHFFFAOYSA-L 0.000 description 1
239000002888 zwitterionic surfactant Substances 0.000 description 1

Classifications

- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D11/00—Control of flow ratio
- G05D11/02—Controlling ratio of two or more flows of fluid or fluent material
- G05D11/13—Controlling ratio of two or more flows of fluid or fluent material characterised by the use of electric means
- G05D11/131—Controlling ratio of two or more flows of fluid or fluent material characterised by the use of electric means by measuring the values related to the quantity of the individual components
- G05D11/133—Controlling ratio of two or more flows of fluid or fluent material characterised by the use of electric means by measuring the values related to the quantity of the individual components with discontinuous action

Landscapes

Physics & Mathematics (AREA)
General Physics & Mathematics (AREA)
Engineering & Computer Science (AREA)
Automation & Control Theory (AREA)
Cosmetics (AREA)
Detergent Compositions (AREA)

CA2733532A 2008-08-26 2009-08-24 Systeme de traitement pour des compositions de soins buccaux Expired - Fee Related CA2733532C (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US12/198,255 US20100055052A1 (en)	2008-08-26	2008-08-26	Processing System for Oral Care Compositions
US12/198,255		2008-08-26
PCT/US2009/054719 WO2010027721A2 (fr)	2008-08-26	2009-08-24	Système de traitement pour des compositions de soins buccaux

Publications (2)

Publication Number	Publication Date
CA2733532A1 true CA2733532A1 (fr)	2010-03-11
CA2733532C CA2733532C (fr)	2013-07-30

Family

ID=41343181

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA2733532A Expired - Fee Related CA2733532C (fr)	2008-08-26	2009-08-24	Systeme de traitement pour des compositions de soins buccaux

Country Status (9)

Country	Link
US (1)	US20100055052A1 (fr)
EP (1)	EP2315617A2 (fr)
JP (1)	JP2012504108A (fr)
CN (1)	CN102238982A (fr)
AU (2)	AU2009288468A1 (fr)
BR (1)	BRPI0917928A2 (fr)
CA (1)	CA2733532C (fr)
MX (1)	MX2011002197A (fr)
WO (1)	WO2010027721A2 (fr)

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EP3017807B1 (fr)	2014-11-04	2019-01-16	The Procter and Gamble Company	Compositions de soins bucco-dentaires anti-tartre fournissant une prévention contre la cristallisation
BR112018076194B1 (pt)	2016-07-14	2022-02-08	Unilever Ip Holdings B.V.	Composição de limpeza para a limpeza da pele, uso da composição de limpeza e recipiente
CN113710328B (zh) *	2019-04-05	2024-01-09	狮王株式会社	洁齿剂组合物
EP4171760A1 (fr) *	2020-07-31	2023-05-03	Colgate-Palmolive Company	Procédé de production d'une composition de soin bucco-dentaire
KR102784210B1 (ko) *	2024-02-28	2025-03-24	케이엠제약(주)	거품 타입의 의치와 치아교정기용 세정제 조성물

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GB2388585A (en) *	2002-05-17	2003-11-19	Unilever Plc	Dosing system with multi-spout nozzle
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JP2005179287A (ja) *	2003-12-22	2005-07-07	Lion Corp	歯磨剤の製造方法
CA2466799C (fr) *	2004-05-07	2011-10-18	Oden Corporation	Melangeur ameliore de veines fluides en continu
US20070044824A1 (en) *	2005-09-01	2007-03-01	Scott William Capeci	Processing system and method of processing
US20070047384A1 (en) *	2005-09-01	2007-03-01	Mclaughlin Jon K	Control system for and method of combining materials
CA2671404A1 (fr) *	2006-12-08	2008-06-19	The Procter & Gamble Company	Procede de realisation de modeles non uniformes de compositions a phases multiples

2008
- 2008-08-26 US US12/198,255 patent/US20100055052A1/en not_active Abandoned
2009
- 2009-08-24 BR BRPI0917928A patent/BRPI0917928A2/pt not_active Application Discontinuation
- 2009-08-24 CN CN2009801331278A patent/CN102238982A/zh active Pending
- 2009-08-24 CA CA2733532A patent/CA2733532C/fr not_active Expired - Fee Related
- 2009-08-24 JP JP2011524066A patent/JP2012504108A/ja active Pending
- 2009-08-24 MX MX2011002197A patent/MX2011002197A/es not_active Application Discontinuation
- 2009-08-24 AU AU2009288468A patent/AU2009288468A1/en not_active Abandoned
- 2009-08-24 EP EP09791824A patent/EP2315617A2/fr not_active Withdrawn
- 2009-08-24 WO PCT/US2009/054719 patent/WO2010027721A2/fr not_active Ceased
2015
- 2015-02-17 AU AU2015200784A patent/AU2015200784A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CN102238982A (zh)	2011-11-09
WO2010027721A3 (fr)	2012-04-05
JP2012504108A (ja)	2012-02-16
CA2733532C (fr)	2013-07-30
WO2010027721A2 (fr)	2010-03-11
AU2015200784A1 (en)	2015-03-05
MX2011002197A (es)	2011-04-05
EP2315617A2 (fr)	2011-05-04
AU2009288468A1 (en)	2010-03-11
BRPI0917928A2 (pt)	2015-11-17
US20100055052A1 (en)	2010-03-04

Publication	Publication Date	Title
US8277824B2 (en)	2012-10-02	Solubilization of cyclohexane-based carboxamide derivatives for use as sensates in consumer products
US9161895B1 (en)	2015-10-20	Compositions and methods for improving overall tooth health and appearance
EP2318356B1 (fr)	2015-03-11	Synthèse de dérivés de cyclohexane utiles comme agents sensoriels dans des produits de consommation
US20090269287A1 (en)	2009-10-29	Oral Care Compositions
EP1998738B1 (fr)	2016-01-13	Compositions de soins bucco-dentaires ayant une esthetique et un gout ameliores pour le consommateur
AU2015200784A1 (en)	2015-03-05	Processing system for oral care compositions

Legal Events

Date	Code	Title	Description
2011-02-08	EEER	Examination request
2020-10-13	MKLA	Lapsed	Effective date: 20200831