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CA2722890A1 - Marqueurs biologiques de l'efficacite de medicaments bases sur egfr/her/erbb - Google Patents

Marqueurs biologiques de l'efficacite de medicaments bases sur egfr/her/erbb Download PDF

Info

Publication number
CA2722890A1
CA2722890A1 CA2722890A CA2722890A CA2722890A1 CA 2722890 A1 CA2722890 A1 CA 2722890A1 CA 2722890 A CA2722890 A CA 2722890A CA 2722890 A CA2722890 A CA 2722890A CA 2722890 A1 CA2722890 A1 CA 2722890A1
Authority
CA
Canada
Prior art keywords
erbb3
cell
phosphorylation
erbb2
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2722890A
Other languages
English (en)
Inventor
Thomas W. Grunt
Waheed Shabbir
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2722890A1 publication Critical patent/CA2722890A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/485Epidermal growth factor [EGF] (urogastrone)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/91Transferases (2.)
    • G01N2333/912Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205Phosphotransferases in general
    • G01N2333/9121Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2722890A 2008-05-25 2009-05-21 Marqueurs biologiques de l'efficacite de medicaments bases sur egfr/her/erbb Abandoned CA2722890A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5601608P 2008-05-25 2008-05-25
US61/056,016 2008-05-25
PCT/US2009/044771 WO2009151908A1 (fr) 2008-05-25 2009-05-21 Marqueurs biologiques de l'efficacité de médicaments basés sur egfr/her/erbb

Publications (1)

Publication Number Publication Date
CA2722890A1 true CA2722890A1 (fr) 2009-12-17

Family

ID=41078344

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2722890A Abandoned CA2722890A1 (fr) 2008-05-25 2009-05-21 Marqueurs biologiques de l'efficacite de medicaments bases sur egfr/her/erbb

Country Status (4)

Country Link
AU (1) AU2009257802A1 (fr)
BR (1) BRPI0911451A2 (fr)
CA (1) CA2722890A1 (fr)
WO (1) WO2009151908A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2638821T3 (es) * 2010-01-13 2017-10-24 Wyeth Llc Un punto de corte en la expresión de la proteína PTEN que identifica tumores con precisión y es predictivo de la respuesta a fármacos a un inhibidor pan-ErbB

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR056857A1 (es) * 2005-12-30 2007-10-24 U3 Pharma Ag Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos
EP1996193A2 (fr) * 2006-03-13 2008-12-03 OSI Pharmaceuticals, Inc. Traitement combiné avec un inhibiteur de kinase egfr et un agent sensibilisant les cellules tumorales aux effets des inhibiteurs de kinase egfr
CA2663595A1 (fr) * 2006-08-07 2008-02-14 The Board Of Regents Of The University Of Texas System Schemas proteomiques de pronostic du cancer et signatures predictives

Also Published As

Publication number Publication date
WO2009151908A1 (fr) 2009-12-17
AU2009257802A1 (en) 2009-12-17
BRPI0911451A2 (pt) 2019-09-24

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead

Effective date: 20130522