CA2781300A1 - Procedes et compositions de traitement de cancers associes a hedgehog - Google Patents

Procedes et compositions de traitement de cancers associes a hedgehog Download PDF

Info

Publication number: CA2781300A1
Authority: CA; Canada
Prior art keywords: cancer; inhibitor; hedgehog; tumor; agent
Prior art date: 2009-11-20
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA2781300A

Other languages

English (en)

Inventor

Veronica Travaglione

John Macdougall

Karen J. Mcgovern

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Infinity Pharmaceuticals Inc

Original Assignee

Infinity Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-11-20

Filing date

2010-11-19

Publication date

2011-05-26

2010-04-16 Priority claimed from US12/762,008 external-priority patent/US20100297118A1/en

2010-11-19 Application filed by Infinity Pharmaceuticals Inc filed Critical Infinity Pharmaceuticals Inc

2011-05-26 Publication of CA2781300A1 publication Critical patent/CA2781300A1/fr

Status Abandoned legal-status Critical Current

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biotechnology (AREA)
Immunology (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Hematology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

CA2781300A 2009-11-20 2010-11-19 Procedes et compositions de traitement de cancers associes a hedgehog Abandoned CA2781300A1 (fr)

Applications Claiming Priority (17)

Application Number	Priority Date	Filing Date	Title
US26318409P	2009-11-20	2009-11-20
US61/263,184		2009-11-20
US29402910P	2010-01-11	2010-01-11
US61/294,029		2010-01-11
US32493410P	2010-04-16	2010-04-16
US61/324,934		2010-04-16
US12/762,008 US20100297118A1 (en)	2007-12-27	2010-04-16	Therapeutic Cancer Treatments
US12/762,008		2010-04-16
US32737310P	2010-04-23	2010-04-23
US61/327,373		2010-04-23
US33136510P	2010-05-04	2010-05-04
US61/331,365		2010-05-04
US35108210P	2010-06-03	2010-06-03
US61/351,082		2010-06-03
US38676310P	2010-09-27	2010-09-27
US61/386,763		2010-09-27
PCT/US2010/057534 WO2011063309A1 (fr)	2009-11-20	2010-11-19	Procédés et compositions de traitement de cancers associés à hedgehog

Publications (1)

Publication Number	Publication Date
CA2781300A1 true CA2781300A1 (fr)	2011-05-26

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ID=44060053

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA2781300A Abandoned CA2781300A1 (fr)	2009-11-20	2010-11-19	Procedes et compositions de traitement de cancers associes a hedgehog

Country Status (5)

Country	Link
EP (1)	EP2502078A1 (fr)
JP (1)	JP2013511549A (fr)
AU (1)	AU2010321773A1 (fr)
CA (1)	CA2781300A1 (fr)
WO (1)	WO2011063309A1 (fr)

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TWI433674B (zh)	2006-12-28	2014-04-11	Infinity Discovery Inc	環杷明（ｃｙｃｌｏｐａｍｉｎｅ）類似物類
EP3190121B1 (fr)	2007-12-27	2019-02-20	Infinity Pharmaceuticals, Inc.	Procédés de réduction stéréo-sélective du derivé 4-en-3-one de cyclopamine
WO2011017551A1 (fr)	2009-08-05	2011-02-10	Infinity Pharmaceuticals, Inc.	Transamination enzymatique d'analogues de cyclopamine
WO2012037217A1 (fr)	2010-09-14	2012-03-22	Infinity Pharmaceuticals, Inc.	Hydrogénation par transfert d'analogues de cyclopamine
TW201300105A (zh) *	2011-05-31	2013-01-01	Piramal Life Sciences Ltd	治療頭頸鱗狀細胞癌之相乘藥物組合物
US9655909B2 (en)	2012-01-12	2017-05-23	Board Of Regents, The University Of Texas System	Personalized medicine for the prediction of therapy targeting the hedgehog pathway
US20150051227A1 (en) *	2012-03-30	2015-02-19	Merck Sharp & Dohme Corp.	Predictive biomarker useful for cancer therapy mediated by a cdk inhibitor
WO2014002922A1 (fr) *	2012-06-26	2014-01-03	アステラス製薬株式会社	Méthode de traitement du cancer par l'utilisation combinée d'un agent anti-cancéreux
CA2903454A1 (fr)	2013-03-12	2014-10-02	Abraxis Bioscience, Llc	Procedes de traitement du cancer du poumon
KR20150126671A (ko) *	2013-03-13	2015-11-12	아브락시스 바이오사이언스, 엘엘씨	소아 고형 종양의 치료 방법
EP2968191B1 (fr)	2013-03-14	2021-06-16	Abraxis BioScience, LLC	Méthodes de traitement du cancer de la vessie
WO2014177915A1 (fr) *	2013-05-01	2014-11-06	Piramal Enterprises Limited	Multi-thérapie anti-cancéreuse utilisant des dérivés de imidazo[4,5-c]quinoline
US9737535B2 (en) *	2014-04-16	2017-08-22	Signal Pharmaceuticals, Llc	Methods for treating cancer using TOR kinase inhibitor combination therapy comprising administering substituted pyrazino[2,3-b]pyrazines
CN106488899B (zh)	2014-05-30	2020-08-18	诺沃梅尔公司	用于化学合成的综合方法
SG11201610534UA (en) *	2014-06-16	2017-01-27	Worldwide Innovative Network	Method for selecting personalized tri-therapy for cancer treatment
WO2016037194A1 (fr) *	2014-09-05	2016-03-10	The Trustees Of Columbia University In The City Of New York	Polythérapie à base d'inhibiteur des voies akt et shh destinée au traitement de carcinomes de cellules basales
MA41514A (fr)	2015-02-13	2017-12-19	Novomer Inc	Procédés intégrés de synthèse chimique
BR112017026103B1 (pt)	2015-06-04	2023-10-03	Sol-Gel Technologies Ltd	Composições tópicas com composto inibidor de hedgehog, sistema de entrega tópica e seus usos
DK3400290T5 (da)	2016-01-08	2024-09-23	Replimune Ltd	Onkolytisk virusstamme
CN107137406B (zh) *	2016-03-01	2021-07-02	江苏恒瑞医药股份有限公司	一种Hedgehog信号通路抑制剂在制备治疗EGFR过度表达的癌症的药物中的用途
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- 2010-11-19 AU AU2010321773A patent/AU2010321773A1/en not_active Abandoned
- 2010-11-19 EP EP10832305A patent/EP2502078A1/fr not_active Withdrawn
- 2010-11-19 JP JP2012540121A patent/JP2013511549A/ja not_active Withdrawn
- 2010-11-19 WO PCT/US2010/057534 patent/WO2011063309A1/fr not_active Ceased
- 2010-11-19 CA CA2781300A patent/CA2781300A1/fr not_active Abandoned

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Publication number	Publication date
EP2502078A1 (fr)	2012-09-26
WO2011063309A1 (fr)	2011-05-26
AU2010321773A1 (en)	2012-06-14
JP2013511549A (ja)	2013-04-04

Publication	Publication Date	Title
CA2781300A1 (fr)	2011-05-26	Procedes et compositions de traitement de cancers associes a hedgehog
US20120010229A1 (en)	2012-01-12	Therapeutic regimens for hedgehog-associated cancers
US20220389090A1 (en)	2022-12-08	Use of il-1beta binding antibodies
US20220257700A1 (en)	2022-08-18	Methods and compositions for treatment of endothelin b receptor expressing tumors
US20150025012A1 (en)	2015-01-22	Methods and compositions for identification, assessment and treatment of cancers associated with hedgehog signaling
US20230081191A1 (en)	2023-03-16	Conjoint therapies for immunomodulation
EP3659621A1 (fr)	2020-06-03	Polythérapies contre le cancer
US20100297118A1 (en)	2010-11-25	Therapeutic Cancer Treatments
JP2011522773A (ja)	2011-08-04	治療剤での癌の処置方法
JP2013510585A (ja)	2013-03-28	癌の同定、評価、予防および治療のための組成物、キットおよび方法
US12295955B2 (en)	2025-05-13	TTP phosphorylation for the identification of personalized medicines
WO2013028907A1 (fr)	2013-02-28	Biomarqueurs prédictifs de la faculté de réponse thérapeutique à des inhibiteurs de hsp90 et leurs utilisations
WO2018235056A1 (fr)	2018-12-27	Anticorps se liant à il-1beta destinés à être utilisés dans le traitement du cancer
US20200268829A1 (en)	2020-08-27	Methods and compositions for inhibiting metastases of an endothelin b receptor expressing cancer
US20220025036A1 (en)	2022-01-27	Use of il-1beta binding antibodies
Germer	2015	19th Surgical Research Days
Komarova	2011	INTERACTION OF BREAST CANCER CELLS WITH
HK1242582A1 (en)	2018-06-29	Combination therapies
HK1242582B (en)	2020-12-18	Combination therapies
NZ753204B2 (en)	2024-01-04	Dual inhibitors of vista and pd-1 pathways

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