CA2603298A1 - Vaccin contre la tuberculose et sa methode de fabrication - Google Patents

Vaccin contre la tuberculose et sa methode de fabrication Download PDF

Info

Publication number: CA2603298A1
Authority: CA; Canada
Prior art keywords: bcg; seq; nucleic acid; tuberculosis; mpb70
Prior art date: 2005-04-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002603298A

Other languages

English (en)

Inventor

Marcel Behr

Serge Mostowy

Danielle Charlet

David Alexander

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

McGill University

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-04-01

Filing date

2006-04-03

Publication date

2006-10-05

2006-04-03 Application filed by Individual filed Critical Individual

2006-10-05 Publication of CA2603298A1 publication Critical patent/CA2603298A1/fr

Status Abandoned legal-status Critical Current

Links

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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Mycology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Pulmonology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

CA002603298A 2005-04-01 2006-04-03 Vaccin contre la tuberculose et sa methode de fabrication Abandoned CA2603298A1 (fr)

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US66724305P	2005-04-01	2005-04-01
US60/667,243		2005-04-01
PCT/CA2006/000503 WO2006102767A1 (fr)	2005-04-01	2006-04-03	Vaccin contre la tuberculose et sa methode de fabrication

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EP (1)	EP1863914A1 (fr)
CA (1)	CA2603298A1 (fr)
WO (1)	WO2006102767A1 (fr)

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US20140127251A1 (en)	2011-04-11	2014-05-08	Alarum Development Ltd.	Vaccines for prevention and treatment of tuberculosis
EP2754452A1 (fr)	2013-01-09	2014-07-16	LIONEX Diagnostics and Therapeutics GmbH	SigC pour la modulation de réponses immunitaires
WO2018184188A1 (fr) *	2017-04-07	2018-10-11	Chengdu Yongan Pharmaceutical Co., Ltd.	Bcg recombiné surexprimant phop-phor
CN119751607B (zh) *	2024-12-25	2025-12-09	华中农业大学	MgdE基因在调控牛分枝杆菌毒力中的应用

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US5693500A (en) *	1988-03-31	1997-12-02	Commonwealth Scientific And Industrial Research Organisation	Diagnosis of Mycobacterium bovis infection
JPH02195895A (ja) *	1989-01-24	1990-08-02	Ajinomoto Co Inc	Ｂｃｇ菌由来免疫タンパクｍｐｂ７０
AU2002302919A1 (en) *	2001-02-22	2002-10-03	Institut Pasteur	Comparative mycobacterial geneomics as a tool for identifying targets for the diagnosis, prophylaxis or treatment of mycobacterioses

2006
- 2006-04-03 EP EP06721759A patent/EP1863914A1/fr not_active Ceased
- 2006-04-03 WO PCT/CA2006/000503 patent/WO2006102767A1/fr not_active Ceased
- 2006-04-03 CA CA002603298A patent/CA2603298A1/fr not_active Abandoned

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EP1863914A1 (fr)	2007-12-12
WO2006102767A1 (fr)	2006-10-05

Publication	Publication Date	Title
Charlet et al.	2005	Reduced expression of antigenic proteins MPB70 and MPB83 in Mycobacterium bovis BCG strains due to a start codon mutation in sigK
JP4053085B2 (ja)	2008-02-27	マイコバクテリアの膜−関連免疫原
US11717565B2 (en)	2023-08-08	Recombinant BCG overexpressing phoP-phoR
TWI334884B (en)	2010-12-21	Anti-bacterial vaccine compositions
EP1492867A2 (fr)	2005-01-05	Identification des regions rd1 et rd5 associees a la virulence afin de permettre le developpement des vaccins ameliores de m. bovis bcg et m. microti
CN106237317A (zh)	2016-12-21	由结核分枝杆菌抗原组成的结核疫苗
US20150240201A1 (en)	2015-08-27	Modified bcg strains with reduced or eliminated activity of lsr2 and pharmaceutical composition comprising same
Matsumoto et al.	1995	Cloning and sequencing of a unique antigen MPT70 from Mycobacterium tuberculosis H37Rv and expression in BCG using E. coli‐mycobacteria shuttle vector
CN102439134B (zh)	2016-01-20	包含过表达PhoP和/或PhoP调节子蛋白的重组BCG菌株的结核疫苗
EP1348036A2 (fr)	2003-10-01	Protection contre les infections mycobacteriennes
CN108330142B (zh)	2021-09-17	一种具有免疫保护作用的美人鱼发光杆菌溶血素Hlych蛋白
CA2603298A1 (fr)	2006-10-05	Vaccin contre la tuberculose et sa methode de fabrication
US20040219585A1 (en)	2004-11-04	Nontypeable haemophilus influenzae virulence factors
US12491238B2 (en)	2025-12-09	Vaccine
US10010597B2 (en)	2018-07-03	Recombinant Mycobacterium bovis BCG expressing antigens of the Mycobacterium marinum ESX-1 secretion system
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