CA2684564A1 - Marqueur de position - Google Patents
Marqueur de position Download PDFInfo
- Publication number
- CA2684564A1 CA2684564A1 CA002684564A CA2684564A CA2684564A1 CA 2684564 A1 CA2684564 A1 CA 2684564A1 CA 002684564 A CA002684564 A CA 002684564A CA 2684564 A CA2684564 A CA 2684564A CA 2684564 A1 CA2684564 A1 CA 2684564A1
- Authority
- CA
- Canada
- Prior art keywords
- marker
- bio
- marker according
- polymeric material
- compatible polymeric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000003550 marker Substances 0.000 title claims abstract description 111
- 239000000463 material Substances 0.000 claims abstract description 150
- 239000004696 Poly ether ether ketone Substances 0.000 claims abstract description 18
- 229920002530 polyetherether ketone Polymers 0.000 claims abstract description 18
- 238000003384 imaging method Methods 0.000 claims abstract description 16
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical group [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229920006260 polyaryletherketone Polymers 0.000 claims abstract description 4
- 238000000034 method Methods 0.000 claims description 25
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 claims description 14
- -1 polysiloxane Polymers 0.000 claims description 14
- MCMNRKCIXSYSNV-UHFFFAOYSA-N ZrO2 Inorganic materials O=[Zr]=O MCMNRKCIXSYSNV-UHFFFAOYSA-N 0.000 claims description 11
- 229910052751 metal Inorganic materials 0.000 claims description 10
- 239000002184 metal Substances 0.000 claims description 10
- 241001465754 Metazoa Species 0.000 claims description 9
- 229920001296 polysiloxane Polymers 0.000 claims description 8
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 6
- 229920001577 copolymer Polymers 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 150000003839 salts Chemical class 0.000 claims description 5
- 239000000560 biocompatible material Substances 0.000 claims description 4
- 150000002148 esters Chemical class 0.000 claims description 4
- 239000004677 Nylon Substances 0.000 claims description 3
- 239000000919 ceramic Substances 0.000 claims description 3
- 229920001778 nylon Polymers 0.000 claims description 3
- 239000005022 packaging material Substances 0.000 claims description 3
- 239000011800 void material Substances 0.000 claims description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 2
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 claims description 2
- 239000004697 Polyetherimide Substances 0.000 claims description 2
- BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims description 2
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims description 2
- 125000005702 oxyalkylene group Chemical group 0.000 claims description 2
- 229920000233 poly(alkylene oxides) Polymers 0.000 claims description 2
- 229920002492 poly(sulfone) Polymers 0.000 claims description 2
- 229920001281 polyalkylene Polymers 0.000 claims description 2
- 239000004417 polycarbonate Substances 0.000 claims description 2
- 229920000515 polycarbonate Polymers 0.000 claims description 2
- 229920000728 polyester Polymers 0.000 claims description 2
- 229920001601 polyetherimide Polymers 0.000 claims description 2
- 229920002635 polyurethane Polymers 0.000 claims description 2
- 239000004814 polyurethane Substances 0.000 claims description 2
- 239000004800 polyvinyl chloride Substances 0.000 claims description 2
- 229920000915 polyvinyl chloride Polymers 0.000 claims description 2
- 125000001174 sulfone group Chemical group 0.000 claims description 2
- 229910052726 zirconium Inorganic materials 0.000 claims description 2
- 229920000642 polymer Polymers 0.000 description 17
- 230000005856 abnormality Effects 0.000 description 9
- 238000002595 magnetic resonance imaging Methods 0.000 description 9
- 229910052715 tantalum Inorganic materials 0.000 description 9
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 9
- 238000011282 treatment Methods 0.000 description 8
- 239000000945 filler Substances 0.000 description 7
- 125000004430 oxygen atom Chemical group O* 0.000 description 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 6
- 229910001220 stainless steel Inorganic materials 0.000 description 6
- 238000013170 computed tomography imaging Methods 0.000 description 5
- 229920001519 homopolymer Polymers 0.000 description 5
- 238000001356 surgical procedure Methods 0.000 description 5
- 238000007794 visualization technique Methods 0.000 description 5
- 238000012307 MRI technique Methods 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 4
- JUPQTSLXMOCDHR-UHFFFAOYSA-N benzene-1,4-diol;bis(4-fluorophenyl)methanone Chemical compound OC1=CC=C(O)C=C1.C1=CC(F)=CC=C1C(=O)C1=CC=C(F)C=C1 JUPQTSLXMOCDHR-UHFFFAOYSA-N 0.000 description 4
- 239000010935 stainless steel Substances 0.000 description 4
- 241000284156 Clerodendrum quadriloculare Species 0.000 description 3
- 239000004698 Polyethylene Substances 0.000 description 3
- 239000004743 Polypropylene Substances 0.000 description 3
- 238000002591 computed tomography Methods 0.000 description 3
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 3
- 229910052737 gold Inorganic materials 0.000 description 3
- 239000010931 gold Substances 0.000 description 3
- 229920001652 poly(etherketoneketone) Polymers 0.000 description 3
- 229920000573 polyethylene Polymers 0.000 description 3
- 229920001155 polypropylene Polymers 0.000 description 3
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 3
- 229910052721 tungsten Inorganic materials 0.000 description 3
- 239000010937 tungsten Substances 0.000 description 3
- 229910001928 zirconium oxide Inorganic materials 0.000 description 3
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 2
- 229930040373 Paraformaldehyde Natural products 0.000 description 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 2
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 2
- 229920001400 block copolymer Polymers 0.000 description 2
- 238000002512 chemotherapy Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 239000011236 particulate material Substances 0.000 description 2
- 229920001643 poly(ether ketone) Polymers 0.000 description 2
- 229920000139 polyethylene terephthalate Polymers 0.000 description 2
- 239000005020 polyethylene terephthalate Substances 0.000 description 2
- 229920006324 polyoxymethylene Polymers 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 238000001959 radiotherapy Methods 0.000 description 2
- 229920005604 random copolymer Polymers 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000010936 titanium Substances 0.000 description 2
- 229910052719 titanium Inorganic materials 0.000 description 2
- 238000004736 wide-angle X-ray diffraction Methods 0.000 description 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical group COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 229920000954 Polyglycolide Polymers 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 125000002947 alkylene group Chemical group 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 125000001033 ether group Chemical group 0.000 description 1
- 230000009969 flowable effect Effects 0.000 description 1
- XUCNUKMRBVNAPB-UHFFFAOYSA-N fluoroethene Chemical group FC=C XUCNUKMRBVNAPB-UHFFFAOYSA-N 0.000 description 1
- 239000008240 homogeneous mixture Substances 0.000 description 1
- 150000003949 imides Chemical class 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920001707 polybutylene terephthalate Polymers 0.000 description 1
- 239000004633 polyglycolic acid Substances 0.000 description 1
- 239000004626 polylactic acid Substances 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 238000000518 rheometry Methods 0.000 description 1
- UONOETXJSWQNOL-UHFFFAOYSA-N tungsten carbide Chemical compound [W+]#[C-] UONOETXJSWQNOL-UHFFFAOYSA-N 0.000 description 1
- 150000003755 zirconium compounds Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/18—Materials at least partially X-ray or laser opaque
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0707671.4 | 2007-04-20 | ||
| GBGB0707671.4A GB0707671D0 (en) | 2007-04-20 | 2007-04-20 | Fiducial marker |
| PCT/GB2008/001347 WO2008129249A2 (fr) | 2007-04-20 | 2008-04-17 | Marqueur de position |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2684564A1 true CA2684564A1 (fr) | 2008-10-30 |
Family
ID=38135153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002684564A Abandoned CA2684564A1 (fr) | 2007-04-20 | 2008-04-17 | Marqueur de position |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP2139420A2 (fr) |
| CA (1) | CA2684564A1 (fr) |
| GB (1) | GB0707671D0 (fr) |
| WO (1) | WO2008129249A2 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2471508A (en) * | 2009-07-02 | 2011-01-05 | Invibio Ltd | Composite enclosure with specific WVTR and impact strength, used in an implantable device |
| WO2013191510A1 (fr) * | 2012-06-22 | 2013-12-27 | 서울대학교 산학협력단 | Matériau métallique médical pour insertion in vivo, comprenant un moyen permettant d'éviter les mouvements in vivo |
| KR101544490B1 (ko) * | 2013-09-05 | 2015-08-13 | 서울대학교산학협력단 | 체내 이동방지 수단이 구비된 체내삽입용 의료용구 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6174330B1 (en) * | 1997-08-01 | 2001-01-16 | Schneider (Usa) Inc | Bioabsorbable marker having radiopaque constituents |
| US6520952B1 (en) * | 2000-03-23 | 2003-02-18 | Neich Medical Co., Ltd. | Ceramic reinforced catheter |
| EP1444993B2 (fr) * | 2003-02-10 | 2013-06-26 | W.C. Heraeus GmbH | Alliage métallique amélioré pour des articles médicaux et des implants |
| US7761138B2 (en) * | 2004-03-12 | 2010-07-20 | Boston Scientific Scimed, Inc. | MRI and X-ray visualization |
| US20050283226A1 (en) * | 2004-06-18 | 2005-12-22 | Scimed Life Systems, Inc. | Medical devices |
| US20060204445A1 (en) * | 2005-03-11 | 2006-09-14 | Anthony Atala | Cell scaffold matrices with image contrast agents |
| GB0521536D0 (en) * | 2005-10-22 | 2005-11-30 | Invibio Ltd | Fiducial marker |
-
2007
- 2007-04-20 GB GBGB0707671.4A patent/GB0707671D0/en not_active Ceased
-
2008
- 2008-04-17 CA CA002684564A patent/CA2684564A1/fr not_active Abandoned
- 2008-04-17 WO PCT/GB2008/001347 patent/WO2008129249A2/fr not_active Ceased
- 2008-04-17 EP EP08737008A patent/EP2139420A2/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008129249A2 (fr) | 2008-10-30 |
| EP2139420A2 (fr) | 2010-01-06 |
| GB0707671D0 (en) | 2007-05-30 |
| WO2008129249A3 (fr) | 2008-12-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20080234532A1 (en) | Fiducial marker | |
| CA2626784A1 (fr) | Marqueur de reference | |
| CA2503949C (fr) | Materiau d'embolisation | |
| EP2300516B1 (fr) | Matières polymères | |
| EP3542748B1 (fr) | Marqueur de tissu de mode d'imagerie multiples | |
| EP2421914B1 (fr) | Matériaux polymères comprenant du sulfate de baryum | |
| Chang et al. | Development and testing of X-ray imaging-enhanced poly-L-lactide bone screws | |
| EP3019208A1 (fr) | Marqueurs implantables | |
| CN1672630A (zh) | 标记物组织的设备和方法 | |
| CA2684564A1 (fr) | Marqueur de position | |
| US10507051B2 (en) | X-ray detectable bioabsorbable bone screw | |
| Sim et al. | Bioabsorbable PLA/PHA composite pins for orthopedic applications: In vitro and in vivo study | |
| WO2022000322A1 (fr) | Matériau composite de développement et sa méthode de préparation et son utilisation, et instrument médical implantable et d'intervention et sa méthode de préparation | |
| CN101283025B (zh) | 生物降解性粒子及其制造方法 | |
| KR20160101955A (ko) | 방사선 치료용 스페이서 | |
| Gorecka et al. | Biodegradable fiducial markers for bimodal near-infrared fluorescence-and X-ray-based imaging | |
| Lin et al. | Evaluating the feasibility of applying cobalt-hydroxyapatite ingots as radiotherapy markers | |
| CN107296986A (zh) | 可于x‑光下显影的生物可吸收性骨钉 | |
| JPWO2018038223A1 (ja) | 骨セメントを活用した放射線治療用の病変識別マーカーおよび放射線治療用の病変識別マーカーキット | |
| KR102258762B1 (ko) | 양성자 치료용 생체 표지자 | |
| Adauto et al. | Direct-joining of a polylactide acid-hydroxyapatite biocomposite with a titanium alloy | |
| TWM527310U (zh) | 可於x-光下顯影之生物可吸收性骨釘 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20140417 |