CA2669379A1 - Ameliorations apportees et associees a des mecanismes d'entrainement a utiliser dans des dispositifs de distribution de medicament - Google Patents

Ameliorations apportees et associees a des mecanismes d'entrainement a utiliser dans des dispositifs de distribution de medicament Download PDF

Info

Publication number: CA2669379A1
Authority: CA; Canada
Prior art keywords: piston rod; drive member; housing; drug delivery; delivery device
Prior art date: 2006-11-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA 2669379

Other languages

English (en)

Other versions

CA2669379C (fr

Inventor

Malcom Boyd

Richard Letham

David Plumptre

Robert Veasey

James May

Matthew Jones

Samuel Liewhelin Ghazaros

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sanofi Aventis Deutschland GmbH

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-11-17

Filing date

2007-11-08

Publication date

2008-05-22

2007-11-08 Application filed by Individual filed Critical Individual

2008-05-22 Publication of CA2669379A1 publication Critical patent/CA2669379A1/fr

2014-12-30 Application granted granted Critical

2014-12-30 Publication of CA2669379C publication Critical patent/CA2669379C/fr

Status Expired - Fee Related legal-status Critical Current

2027-11-08 Anticipated expiration legal-status Critical

Links

238000012377 drug delivery Methods 0.000 title claims abstract description 61
230000007246 mechanism Effects 0.000 title claims abstract description 38
238000004519 manufacturing process Methods 0.000 claims description 2
230000033001 locomotion Effects 0.000 description 56
238000007373 indentation Methods 0.000 description 40
230000004913 activation Effects 0.000 description 25
230000003993 interaction Effects 0.000 description 15
239000003814 drug Substances 0.000 description 13
229940126601 medicinal product Drugs 0.000 description 11
230000009471 action Effects 0.000 description 10
230000000007 visual effect Effects 0.000 description 10
230000000717 retained effect Effects 0.000 description 7
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 6
230000000881 depressing effect Effects 0.000 description 5
238000010276 construction Methods 0.000 description 4
102000004877 Insulin Human genes 0.000 description 3
108090001061 Insulin Proteins 0.000 description 3
230000005540 biological transmission Effects 0.000 description 3
238000002347 injection Methods 0.000 description 3
239000007924 injection Substances 0.000 description 3
229940125396 insulin Drugs 0.000 description 3
239000000463 material Substances 0.000 description 3
230000008901 benefit Effects 0.000 description 2
150000001875 compounds Chemical class 0.000 description 2
230000008878 coupling Effects 0.000 description 2
238000010168 coupling process Methods 0.000 description 2
238000005859 coupling reaction Methods 0.000 description 2
239000000122 growth hormone Substances 0.000 description 2
229940127215 low-molecular weight heparin Drugs 0.000 description 2
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
102000018997 Growth Hormone Human genes 0.000 description 1
108010051696 Growth Hormone Proteins 0.000 description 1
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
239000008280 blood Substances 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
239000000356 contaminant Substances 0.000 description 1
238000007599 discharging Methods 0.000 description 1
229940079593 drug Drugs 0.000 description 1
239000000428 dust Substances 0.000 description 1
239000008103 glucose Substances 0.000 description 1
229960002897 heparin Drugs 0.000 description 1
229920000669 heparin Polymers 0.000 description 1
229940025708 injectable product Drugs 0.000 description 1
230000001788 irregular Effects 0.000 description 1
239000007788 liquid Substances 0.000 description 1
230000007774 longterm Effects 0.000 description 1
239000003055 low molecular weight heparin Substances 0.000 description 1
238000000034 method Methods 0.000 description 1
239000008194 pharmaceutical composition Substances 0.000 description 1
230000001766 physiological effect Effects 0.000 description 1
238000003825 pressing Methods 0.000 description 1
238000004064 recycling Methods 0.000 description 1
239000000243 solution Substances 0.000 description 1
239000000725 suspension Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
- A61M2005/3104—Caps for syringes without needle
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49826—Assembling or joining

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Anesthesiology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Life Sciences & Earth Sciences (AREA)
Vascular Medicine (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Infusion, Injection, And Reservoir Apparatuses (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Transmission Devices (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Catching Or Destruction (AREA)

CA 2669379 2006-11-17 2007-11-08 Ameliorations apportees et associees a des mecanismes d'entrainement a utiliser dans des dispositifs de distribution de medicament Expired - Fee Related CA2669379C (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP06023951.4		2006-11-17
EP20060023951 EP1923083A1 (fr)	2006-11-17	2006-11-17	Mécanismes d'entraînement destinés à être utilisés dans des dispositifs d'administration de médicaments
PCT/EP2007/009676 WO2008058668A1 (fr)	2006-11-17	2007-11-08	Améliorations apportées et associées à des mécanismes d'entraînement à utiliser dans des dispositifs de distribution de médicament

Publications (2)

Publication Number	Publication Date
CA2669379A1 true CA2669379A1 (fr)	2008-05-22
CA2669379C CA2669379C (fr)	2014-12-30

Family

ID=37845160

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CA 2669379 Expired - Fee Related CA2669379C (fr)	2006-11-17	2007-11-08	Ameliorations apportees et associees a des mecanismes d'entrainement a utiliser dans des dispositifs de distribution de medicament
CA 2669374 Expired - Fee Related CA2669374C (fr)	2006-11-17	2007-11-08	Ameliorations apportees et associees a des mecanismes d'entrainement a utiliser dans des dispositifs de distribution de medicament

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
CA 2669374 Expired - Fee Related CA2669374C (fr)	2006-11-17	2007-11-08	Ameliorations apportees et associees a des mecanismes d'entrainement a utiliser dans des dispositifs de distribution de medicament

Country Status (39)

Country	Link
US (4)	US7993301B2 (fr)
EP (4)	EP1923083A1 (fr)
JP (2)	JP5286275B2 (fr)
KR (2)	KR101422056B1 (fr)
CN (2)	CN101622023B (fr)
AR (2)	AR063836A1 (fr)
AU (2)	AU2007321449B2 (fr)
BR (2)	BRPI0719069A2 (fr)
CA (2)	CA2669379C (fr)
CL (2)	CL2007003300A1 (fr)
CO (2)	CO6210736A2 (fr)
CR (2)	CR10770A (fr)
CY (1)	CY1113800T1 (fr)
DK (2)	DK2081622T3 (fr)
EC (2)	ECSP099334A (fr)
EG (1)	EG25189A (fr)
ES (1)	ES2401354T3 (fr)
GT (2)	GT200900131A (fr)
HN (2)	HN2009001000A (fr)
IL (2)	IL198747A (fr)
MA (2)	MA30884B1 (fr)
ME (1)	ME00589A (fr)
MX (2)	MX2009005093A (fr)
MY (2)	MY148971A (fr)
NI (2)	NI200900087A (fr)
NO (2)	NO20092322L (fr)
NZ (2)	NZ577007A (fr)
PE (2)	PE20081203A1 (fr)
PL (1)	PL2091599T3 (fr)
PT (1)	PT2091599E (fr)
RU (2)	RU2460546C2 (fr)
SI (1)	SI2091599T1 (fr)
SV (2)	SV2009003263A (fr)
TN (2)	TN2009000192A1 (fr)
TW (2)	TW200833387A (fr)
UA (2)	UA96167C2 (fr)
UY (2)	UY30721A1 (fr)
WO (2)	WO2008058668A1 (fr)
ZA (2)	ZA200903077B (fr)

Families Citing this family (166)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2003209095A1 (en)	2002-02-11	2003-09-04	Antares Pharma, Inc.	Intradermal injector
US11590286B2 (en)	2004-11-22	2023-02-28	Kaleo, Inc.	Devices, systems and methods for medicament delivery
US7648483B2 (en)	2004-11-22	2010-01-19	Intelliject, Inc.	Devices, systems and methods for medicament delivery
US10737028B2 (en)	2004-11-22	2020-08-11	Kaleo, Inc.	Devices, systems and methods for medicament delivery
CN101087625B (zh)	2004-11-22	2012-02-22	因特利杰克特有限公司	用于药物供给的装置和系统
US7947017B2 (en)	2004-11-22	2011-05-24	Intelliject, Inc.	Devices, systems and methods for medicament delivery
DK1850892T4 (da)	2005-01-24	2023-06-06	Antares Pharma Inc	Forfyldt nål-assisteret sprøjtejetinjektor
NZ560516A (en)	2005-02-01	2010-12-24	Intelliject Inc	A delivery system where a medicant is automatically delivered on activation as well as a recorded instruction
US8251947B2 (en)	2006-05-03	2012-08-28	Antares Pharma, Inc.	Two-stage reconstituting injector
US9144648B2 (en)	2006-05-03	2015-09-29	Antares Pharma, Inc.	Injector with adjustable dosing
US8226618B2 (en)	2006-05-16	2012-07-24	Novo Nordisk A/S	Gearing mechanism for an injection device
EP1923083A1 (fr)	2006-11-17	2008-05-21	Sanofi-Aventis Deutschland GmbH	Mécanismes d'entraînement destinés à être utilisés dans des dispositifs d'administration de médicaments
US7967795B1 (en)	2010-01-19	2011-06-28	Lamodel Ltd.	Cartridge interface assembly with driving plunger
BRPI0817907B8 (pt)	2007-10-02	2021-06-22	Lamodel Ltd	aparelho para administrar uma substância a um indivíduo
US9345836B2 (en)	2007-10-02	2016-05-24	Medimop Medical Projects Ltd.	Disengagement resistant telescoping assembly and unidirectional method of assembly for such
US10420880B2 (en)	2007-10-02	2019-09-24	West Pharma. Services IL, Ltd.	Key for securing components of a drug delivery system during assembly and/or transport and methods of using same
US9656019B2 (en)	2007-10-02	2017-05-23	Medimop Medical Projects Ltd.	Apparatuses for securing components of a drug delivery system during transport and methods of using same
US8814834B2 (en)	2008-03-10	2014-08-26	Antares Pharma, Inc.	Injector safety device
EP2258475B1 (fr) *	2008-03-24	2016-11-02	Showa Denko K.K.	Catalyseur et procédé de fabrication et son utilisation
MX2010012691A (es)	2008-05-20	2011-03-30	Avant Medical Corp Star	Sistema auto-inyector.
US8052645B2 (en)	2008-07-23	2011-11-08	Avant Medical Corp.	System and method for an injection using a syringe needle
US20090308895A1 (en) *	2008-06-13	2009-12-17	Reynolds David L	Rack and pinon drive for by-pass cartridge
EP3581224A1 (fr)	2008-08-05	2019-12-18	Antares Pharma, Inc.	Injecteur à dosage multiple
US12097357B2 (en)	2008-09-15	2024-09-24	West Pharma. Services IL, Ltd.	Stabilized pen injector
US9393369B2 (en)	2008-09-15	2016-07-19	Medimop Medical Projects Ltd.	Stabilized pen injector
CN102186517B (zh) *	2008-09-18	2013-07-24	贝克顿·迪金森公司	具有带棘齿的柱塞的医用注射器
EP2193816A1 (fr) *	2008-12-02	2010-06-09	Sanofi-Aventis Deutschland GmbH	Dispositif d'administration médicale
EP2193817A1 (fr) *	2008-12-02	2010-06-09	Sanofi-Aventis Deutschland GmbH	Ensemble de commande adapté pour un dispositif d'administration de médicaments et dispositif d'administration de médicaments
TWI555546B (zh) *	2008-12-02	2016-11-01	賽諾菲阿凡提斯德意志有限公司	藥物傳輸裝置及其操作方法
EP2196233A1 (fr)	2008-12-12	2010-06-16	Sanofi-Aventis Deutschland GmbH	Mécanisme de commande réenclenchable pour dispositif d'administration de médicaments et dispositif d'administration de médicaments
EP2198904A1 (fr) *	2008-12-19	2010-06-23	Sanofi-Aventis Deutschland GmbH	Mécanisme de verrouillage pour dispositif d'administration de médicaments et dispositif d'administration de médicaments
EP2201974A1 (fr)	2008-12-23	2010-06-30	Sanofi-Aventis Deutschland GmbH	Dispositif d'administration de médicaments
EP2201971A1 (fr) *	2008-12-23	2010-06-30	Sanofi-Aventis Deutschland GmbH	Dispositif d'administration de médicaments
WO2010100213A1 (fr)	2009-03-05	2010-09-10	Sanofi-Aventis Deutschland Gmbh	Dispositif d'administration de médicaments
EP2408493B1 (fr)	2009-03-20	2024-07-24	Antares Pharma, Inc.	Système d'injection d'agents dangereux
CN102422336B (zh)	2009-03-31	2016-01-20	赛诺菲-安万特德国有限公司	使用粘结剂制造药物递送装置主体的方法和药物递送装置主体
JP5667160B2 (ja) *	2009-03-31	2015-02-12	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	薬剤送達デバイスにおける及び薬剤送達デバイスに関する改良
DK2414007T3 (en)	2009-03-31	2015-06-08	Sanofi Aventis Deutschland	PHARMACEUTICAL Feed mechanism
CA2756141A1 (fr)	2009-03-31	2010-10-07	Sanofi-Aventis Deutschland Gmbh	Corps de dispositif d'administration de medicament
JP5787875B2 (ja)	2009-03-31	2015-09-30	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	機構を有する医療デバイス及び医療デバイス内における低摩擦合成材料の使用
CN102448521B (zh)	2009-03-31	2014-07-23	赛诺菲-安万特德国有限公司	药物递送装置
US9457148B2 (en)	2009-04-01	2016-10-04	Shl Group Ab	Medicament delivery device
EP2432524B1 (fr)	2009-05-20	2017-04-12	Sanofi-Aventis Deutschland GmbH	Dispositif d'approvisionnement de médicament et utilisation d'un rouleau rotatif dans un dispositif d'approvisionnement de médicament
EP2292286A1 (fr) *	2009-09-07	2011-03-09	Sanofi-Aventis Deutschland GmbH	Mécanisme de commande pour dispositif d'administration de médicaments et dispositif d'administration de médicaments
EP2475411B1 (fr) *	2009-09-07	2014-12-31	Sanofi-Aventis Deutschland GmbH	Mécanisme d'entrainement pour dispositif d'approvisionnement de médicament
US8157769B2 (en)	2009-09-15	2012-04-17	Medimop Medical Projects Ltd.	Cartridge insertion assembly for drug delivery system
US10071196B2 (en)	2012-05-15	2018-09-11	West Pharma. Services IL, Ltd.	Method for selectively powering a battery-operated drug-delivery device and device therefor
US10071198B2 (en)	2012-11-02	2018-09-11	West Pharma. Servicees IL, Ltd.	Adhesive structure for medical device
TW201121600A (en)	2009-09-29	2011-07-01	Sanofi Aventis Deutschland	Assembly for a drug delivery device
CA2773459A1 (fr)	2009-09-30	2011-04-07	Sanofi-Aventis Deutschland Gmbh	Dispositif de delivrance de medicament reinitialisable
EP2482889B1 (fr) *	2009-09-30	2016-02-10	Sanofi-Aventis Deutschland GmbH	Assemblage pour dispositif d'administration de médicaments
WO2011039209A1 (fr) *	2009-09-30	2011-04-07	Sanofi-Aventis Deutschland Gmbh	Ensemble tige de manoeuvre pour dispositif de distribution de médicament
AR078457A1 (es) *	2009-09-30	2011-11-09	Sanofi Aventis Deutschland	Mecanismo accionador para un dispositivo de descarga de farmacos
BR112012007310A2 (pt) *	2009-09-30	2016-04-19	Sanofi Aventis Deutschland	mecanismo de acionamento para um dispositivo de entrega de fármaco e uso de um membro de reajuste para um mecanismo de acionamento
TW201121601A (en)	2009-09-30	2011-07-01	Sanofi Aventis Deutschland	Drive assembly, piston rod, drug delivery device, and use of a spring
AR079004A1 (es)	2009-09-30	2011-12-21	Sanofi Aventis Deutschland	Dispositivo de dispensacion de farmacos
AR078459A1 (es) *	2009-09-30	2011-11-09	Sanofi Aventis Deutschland	Conjunto de accionamiento, vastago de piston, dispositivo para la entrega de drogas, y uso de un resorte
JP5805092B2 (ja)	2009-09-30	2015-11-04	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	注射デバイス
US20120283660A1 (en)	2009-09-30	2012-11-08	Sanofi-Aventis Deutschland Gmbh	Method and assembly for a drug delivery device
WO2011039227A2 (fr)	2009-09-30	2011-04-07	Sanofi-Aventis Deutschland Gmbh	Procédé et ensemble pour dispositif d'administration de médicament
DK2482891T3 (en)	2009-09-30	2017-02-06	Sanofi Aventis Deutschland	RETRIEVABLE DRIVING AND PHARMACEUTICAL SUPPLY
WO2011039201A2 (fr) *	2009-09-30	2011-04-07	Sanofi-Aventis Deutschland Gmbh	Mécanisme d'entraînement pour un dispositif de distribution de médicaments, et élément élastique pour un mécanisme d'entraînement
WO2011039205A2 (fr)	2009-09-30	2011-04-07	Sanofi-Aventis Deutschland Gmbh	Dispositif de délivrance de médicament et élément d'entraînement pour de dispositif
GB0918145D0 (en)	2009-10-16	2009-12-02	Owen Mumford Ltd	Injector apparatus
JP5777629B2 (ja)	2009-11-03	2015-09-09	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	薬物送達デバイス用のアセンブリ及び薬物送達デバイス
US8348898B2 (en)	2010-01-19	2013-01-08	Medimop Medical Projects Ltd.	Automatic needle for drug pump
CN103120819B (zh) *	2010-03-31	2015-05-06	Shl集团有限责任公司	药物输送设备
EP2552510B1 (fr)	2010-03-31	2017-02-15	Sanofi-Aventis Deutschland GmbH	Ensemble de dispositifs d'administration de médicaments avec aides d'identification tactiles ou visuelles
US8986259B2 (en)	2010-03-31	2015-03-24	Sanofi-Aventis Deutschland Gmbh	Piston rod assembly for a drug delivery device
WO2011141907A1 (fr)	2010-05-10	2011-11-17	Medimop Medical Projects Ltd.	Injecteur précis de faible volume
CA2806983A1 (fr)	2010-08-06	2012-02-09	Sanofi-Aventis Deutschland Gmbh	Assemblage destine a un dispositif d'administration de medicament, tige de piston et dispositif d'administration de medicament
DE202011110811U1 (de)	2010-08-06	2016-07-15	Sanofi-Aventis Deutschland Gmbh	Patronenhalter zum Zusammenbauen einer Patroneneinheit für eine Medikamenten-Verabreichungsvorrichtung
JP5955332B2 (ja)	2010-11-12	2016-07-20	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	薬剤送達デバイスおよび薬剤送達デバイスのための方法
EP2452710A1 (fr)	2010-11-12	2012-05-16	Sanofi-Aventis Deutschland GmbH	Assemblage pour dispositif d'administration de médicaments et tige de piston
WO2012065965A1 (fr)	2010-11-19	2012-05-24	Sanofi-Aventis Deutschland Gmbh	Capuchon pour dispositif d'administration de médicament et procédé de fabrication d'un capuchon pour dispositif d'administration de médicament
DK2460551T3 (en)	2010-12-06	2016-08-15	Sanofi Aventis Deutschland	Drug delivery device with dose knob lock arrangement
EP2460552A1 (fr)	2010-12-06	2012-06-06	Sanofi-Aventis Deutschland GmbH	Dispositif d'administration de médicaments avec mécanisme de blocage du déclencheur
US9173999B2 (en)	2011-01-26	2015-11-03	Kaleo, Inc.	Devices and methods for delivering medicaments from a multi-chamber container
US8939943B2 (en)	2011-01-26	2015-01-27	Kaleo, Inc.	Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8627816B2 (en)	2011-02-28	2014-01-14	Intelliject, Inc.	Medicament delivery device for administration of opioid antagonists including formulations for naloxone
JP5823542B2 (ja) *	2011-03-17	2015-11-25	ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ，ＤｉｃｋｉｎｓｏｎＡｎｄＣｏｍｐａｎｙ	ラチェット動作のプランジャーを持つ医療用注射器
USD702834S1 (en) *	2011-03-22	2014-04-15	Medimop Medical Projects Ltd.	Cartridge for use in injection device
CA2833748C (fr)	2011-04-20	2019-07-16	Amgen Inc.	Appareil auto-injecteur
AR086255A1 (es)	2011-05-06	2013-11-27	Sanofi Aventis Deutschland	Conjunto para un dispositivo de administracion de farmacos y dispositivo de administracion de farmacos
AR086257A1 (es)	2011-05-06	2013-11-27	Sanofi Aventis Deutschland	Dispositivo de administracion de farmacos y soporte de cartucho para un dispositivo de administracion de farmacos
DK2707062T3 (en) *	2011-05-13	2018-01-08	Sanofi Aventis Deutschland	DEVICE FOR PHARMACEUTICAL DISPENSER DEVICE
TWI574708B (zh) *	2011-06-17	2017-03-21	賽諾菲阿凡提斯德意志有限公司	用於藥物遞送裝置的卡匣支撐器總成
US9220660B2 (en)	2011-07-15	2015-12-29	Antares Pharma, Inc.	Liquid-transfer adapter beveled spike
US8496619B2 (en)	2011-07-15	2013-07-30	Antares Pharma, Inc.	Injection device with cammed ram assembly
EP2760507B8 (fr)	2011-09-29	2018-04-18	Sanofi-Aventis Deutschland GmbH	Dispositif d'administration de médicaments et procédé d'assamblage d'un dispositif d'administration de médicaments
CN103998082B (zh) *	2011-10-14	2016-11-16	赛诺菲-安万特德国有限公司	用于药物输送装置的组件
EP2583706A1 (fr) *	2011-10-21	2013-04-24	Sanofi-Aventis Deutschland GmbH	Auto-injecteur
MX2014007115A (es)	2011-12-15	2014-09-08	Sanofi Aventis Deutschland	Deposito, metodo y montaje para un sistema de suministro de farmacos.
US8834449B2 (en)	2012-01-23	2014-09-16	Ikomed Technologies, Inc.	Mixing syringe
US9751056B2 (en)	2012-01-23	2017-09-05	Merit Medical Systems, Inc.	Mixing syringe
KR20150003179A (ko)	2012-03-06	2015-01-08	안타레스 팔마, 인코퍼레이티드	분리력 특징을 가진 사전충전형 주사기
US10004854B2 (en)	2012-03-07	2018-06-26	West Pharmaceutical Services, Inc.	Low radial profile needle safety device
US9907916B2 (en)	2012-03-07	2018-03-06	West Pharmaceutical Services, Inc.	Low radial profile needle safety device
US9072827B2 (en)	2012-03-26	2015-07-07	Medimop Medical Projects Ltd.	Fail safe point protector for needle safety flap
US9950125B2 (en)	2012-04-06	2018-04-24	Antares Pharma, Inc.	Needle assisted jet injection administration of testosterone compositions
KR101368867B1 (ko) *	2012-04-12	2014-02-28	방시열	의료용 약물 주입장치
WO2013156516A1 (fr)	2012-04-19	2013-10-24	Sanofi-Aventis Deutschland Gmbh	Ensemble pour dispositif d'administration de médicaments et dispositif d'administration de médicaments
USD898908S1 (en)	2012-04-20	2020-10-13	Amgen Inc.	Pharmaceutical product cassette for an injection device
KR101368920B1 (ko) *	2012-04-30	2014-02-28	방시열	의료용 약물 주입장치
WO2013169804A1 (fr)	2012-05-07	2013-11-14	Antares Pharma, Inc.	Dispositif d'injection par jet assisté par une aiguille, présentant une force de déclenchement réduite
US9522235B2 (en)	2012-05-22	2016-12-20	Kaleo, Inc.	Devices and methods for delivering medicaments from a multi-chamber container
EP2682142A1 (fr) *	2012-07-06	2014-01-08	Sanofi-Aventis Deutschland GmbH	Auto-injecteur
JP6298056B2 (ja)	2012-08-20	2018-03-20	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	薬物送達デバイス用キャップおよび薬物送達デバイス
EP2719420A1 (fr)	2012-10-12	2014-04-16	Becton Dickinson France	Adaptateur pour un dispositif d'administration de médicament et procédé pour monter ledit adaptateur sur celui-ci
WO2014064023A1 (fr) *	2012-10-23	2014-05-01	Sanofi-Aventis Deutschland Gmbh	Système de compteur destiné à être utilisé dans un dispositif d'administration de médicament
US9421323B2 (en)	2013-01-03	2016-08-23	Medimop Medical Projects Ltd.	Door and doorstop for portable one use drug delivery apparatus
US9744302B2 (en)	2013-02-11	2017-08-29	Antares Pharma, Inc.	Needle assisted jet injection device having reduced trigger force
EP3572108A1 (fr)	2013-03-11	2019-11-27	Antares Pharma, Inc.	Injecteur de dose avec système à pignon
WO2014165136A1 (fr)	2013-03-12	2014-10-09	Antares Pharma, Inc.	Seringues pré-remplies à volume constant et leurs trousses
EP3881880B1 (fr)	2013-03-13	2025-04-02	Sanofi-Aventis Deutschland GmbH	Ensemble pour un dispositif d'administration de médicament comprenant un élément de rétroaction
MX2015012900A (es)	2013-03-14	2016-04-04	Norton Healthcare Ltd	Mecanismo de dispensacion para un dispositivo medico.
US10220152B2 (en)	2013-03-14	2019-03-05	Norton Healthcare Limited	Dispensing mechanism for a medical device
CA2906253C (fr) *	2013-03-14	2018-04-24	Norton Healthcare Limited	Mecanisme de distribution pour un dispositif medical
GB2511806A (en) *	2013-03-14	2014-09-17	Norton Healthcare Ltd	Dispensing mechanism for a medical device
US10492990B2 (en)	2013-03-15	2019-12-03	Amgen Inc.	Drug cassette, autoinjector, and autoinjector system
US9011164B2 (en)	2013-04-30	2015-04-21	Medimop Medical Projects Ltd.	Clip contact for easy installation of printed circuit board PCB
KR102375565B1 (ko)	2013-09-23	2022-03-17	사노피-아벤티스 도이칠란트 게엠베하	약물 전달 장치용 어셈블리 및 약물 전달 장치
EP3057517B1 (fr)	2013-10-15	2020-04-08	Stryker Corporation	Dispositif permettant de créer un espace vide dans un tissu vivant, comprenant une poignée dotée d'un bouton de commande qui peut être réglé quelle que soit l'orientation de la poignée
US10617825B2 (en)	2014-06-27	2020-04-14	Sanofi-Aventis Deutschland Gmbh	Drug delivery device
US9517307B2 (en)	2014-07-18	2016-12-13	Kaleo, Inc.	Devices and methods for delivering opioid antagonists including formulations for naloxone
MA41101A (fr)	2014-12-03	2017-10-10	Lilly Co Eli	Dispositif d'injection de médicament automatique comportant une indication audible de progression d'injection
US10668222B2 (en)	2014-12-10	2020-06-02	Sanofi	Assembly for a drug delivery device and drug delivery device
KR102634489B1 (ko)	2015-03-10	2024-02-07	리제너론 파아마슈티컬스, 인크.	무균 관통 시스템 및 방법
WO2016154427A2 (fr)	2015-03-24	2016-09-29	Kaleo, Inc.	Dispositifs et procédés pour administrer un médicament lyophilisé
US10293120B2 (en)	2015-04-10	2019-05-21	West Pharma. Services IL, Ltd.	Redundant injection device status indication
US10149943B2 (en)	2015-05-29	2018-12-11	West Pharma. Services IL, Ltd.	Linear rotation stabilizer for a telescoping syringe stopper driverdriving assembly
EP4252798A3 (fr)	2015-06-04	2023-10-25	Medimop Medical Projects Ltd.	Mode d'insertion de cartouche pour dispositif d'administration de médicaments
WO2017004345A1 (fr)	2015-06-30	2017-01-05	Kaleo, Inc.	Auto-injecteurs destinés à l'administration d'un médicament à l'intérieur d'une seringue pré-remplie
US10576207B2 (en)	2015-10-09	2020-03-03	West Pharma. Services IL, Ltd.	Angled syringe patch injector
US9987432B2 (en)	2015-09-22	2018-06-05	West Pharma. Services IL, Ltd.	Rotation resistant friction adapter for plunger driver of drug delivery device
EP3147034A1 (fr) *	2015-09-25	2017-03-29	Sulzer Mixpac AG	Applicateur pour éjecter des doses d'un composant fluide
CN112972833B (zh)	2015-10-09	2024-01-09	西医药服务以色列分公司	注射器针帽脱离器
US11071832B2 (en)	2015-11-27	2021-07-27	Sanofi-Aventis Deutschland Gmbh	Medicament injection device
EP3187213A1 (fr)	2015-12-29	2017-07-05	Galderma S.A.	Seringue avec mécanisme à cliquet
EP3187217A1 (fr)	2015-12-29	2017-07-05	Galderma S.A.	Seringue avec mécanisme à cliquet
JP6885960B2 (ja)	2016-01-21	2021-06-16	ウェストファーマサービシーズイスラエルリミテッド	視覚的インジケータを有する薬剤デリバリデバイス
CN109219456B (zh)	2016-01-21	2020-05-15	西医药服务以色列有限公司	自动注射器中的力牵制
JP6542481B2 (ja)	2016-01-21	2019-07-10	ウェストファーマサービシーズイスラエルリミテッド	システム
US11389597B2 (en)	2016-03-16	2022-07-19	West Pharma. Services IL, Ltd.	Staged telescopic screw assembly having different visual indicators
EP3442623B1 (fr)	2016-04-15	2021-01-20	Santen Pharmaceutical Co., Ltd.	Seringue de dosage de microlitre répétable et précis
CN109310831B (zh)	2016-06-02	2021-11-23	西医药服务以色列有限公司	三位置针缩回
EP3490635B1 (fr)	2016-08-01	2021-11-17	West Pharma. Services Il, Ltd.	Ressort pour prévenir la fermeture incomplet de la porte
CN109562229B (zh)	2016-08-01	2021-07-13	西医药服务以色列有限公司	抗旋转药筒销
AU2017379094B2 (en)	2016-12-23	2023-08-24	Kaleo, Inc.	Medicament delivery device and methods for delivering drugs to infants and children
EP3338838A1 (fr)	2016-12-23	2018-06-27	Sanofi-Aventis Deutschland GmbH	Dispositifs d'administration de médicaments
ES2919934T3 (es)	2017-05-05	2022-07-29	Regeneron Pharma	Autoinyector y procedimientos de uso relacionados
IL301683B2 (en)	2017-05-17	2025-02-01	Massachusetts Inst Technology	Self-healing systems and related components and methods
US11541015B2 (en)	2017-05-17	2023-01-03	Massachusetts Institute Of Technology	Self-righting systems, methods, and related components
JP6921997B2 (ja)	2017-05-30	2021-08-18	ウェストファーマサービシーズイスラエルリミテッド	ウェアラブル注射器のモジュラ駆動トレイン
MX2020006177A (es)	2017-12-13	2020-09-03	Regeneron Pharma	Dispositivos y metodos para administracion exacta de dosis.
WO2019126421A1 (fr)	2017-12-22	2019-06-27	West Pharma. Services Il., Ltd.	Injecteur utilisable avec des cartouches de différentes dimensions
EP3793667A1 (fr)	2018-05-17	2021-03-24	Massachusetts Institute of Technology	Système pour stimulation électrique
WO2020140040A1 (fr)	2018-12-29	2020-07-02	Kaleo, Inc.	Dispositifs et procédés de distribution de substances dans une seringue pré-remplie
US11771829B2 (en)	2019-02-01	2023-10-03	Massachusetts Institute Of Technology	Systems and methods for liquid injection
WO2020219392A2 (fr)	2019-04-24	2020-10-29	Stryker Corporation	Systèmes et procédés d'augmentation hors-axe d'un corps vertébral
CN118718180A (zh)	2019-06-05	2024-10-01	里珍纳龙药品有限公司	用于精确剂量递送的装置及方法
IL290026B1 (en)	2019-08-09	2025-10-01	Kaleo Inc	Devices and methods for transferring materials into a prefilled syringe
CA3255868A1 (fr) *	2019-08-30	2025-06-28	Lilly Co Eli	Procédés et appareil pour déterminer une dose de dispositif
US12337155B2 (en) *	2019-11-21	2025-06-24	InnoCAT Ltd.	Liquid delivery device and method
US12268847B1 (en)	2021-02-10	2025-04-08	Kaleo, Inc.	Devices and methods for delivery of substances within a medicament container
USD1007676S1 (en)	2021-11-16	2023-12-12	Regeneron Pharmaceuticals, Inc.	Wearable autoinjector

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2725877A (en) *	1950-12-22	1955-12-06	Reiter David	Hypodermic syringe with feed control
US4465478A (en) *	1982-10-14	1984-08-14	Collagen Corporation	Syringe force amplification device
SU1745103A3 (ru) *	1986-01-20	1992-06-30	Мицубиси Пенсл Ко., Лтд (Фирма)	Шприц
DK166948B1 (da) *	1988-02-10	1993-08-09	Dcp Af 1988 As	Doseringsenhed til dosering af et antal afmaalte maengder af en vaeske, saasom insulin, fra en glastubule
GB9007113D0 (en) *	1990-03-29	1990-05-30	Sams Bernard	Dispensing device
GB9503969D0 (en) *	1995-02-28	1995-04-19	Sams Bernard	Incrementing mechanism
DE29606540U1 (de) *	1996-04-10	1997-08-07	Mühlbauer, Ernst, 22547 Hamburg	Applikationsgerät für Dentalmasse
US6003736A (en) *	1997-06-09	1999-12-21	Novo Nordisk A/S	Device for controlled dispensing of a dose of a liquid contained in a cartridge
US6074372A (en) *	1997-06-09	2000-06-13	Novo Nordisk A/S	Dose setting mechanism and an injection syringe having such a dose setting mechanism
US6796970B1 (en) *	1997-06-17	2004-09-28	Novo Nordisk A/S	Dose setting device
FR2767479B1 (fr) *	1997-08-22	1999-10-22	Aguettant Lab	Dispositif d'injection de medicament
US6245046B1 (en) *	1999-05-03	2001-06-12	University Of New Mexico	Reciprocating syringes
US7458956B1 (en) *	1999-11-12	2008-12-02	Boston Scientific Scimed, Inc.	Apparatus for delivery of controlled doses of therapeutic drugs in endoluminal procedures
US20050277887A1 (en) *	2000-05-08	2005-12-15	Joel Douglas	Micro infusion drug delivery device
SE0001893D0 (sv) *	2000-05-22	2000-05-22	Pharmacia & Upjohn Ab	Medical arrangement
US6663602B2 (en) *	2000-06-16	2003-12-16	Novo Nordisk A/S	Injection device
GB0026647D0 (en) *	2000-10-31	2000-12-13	Glaxo Group Ltd	Medicament dispenser
WO2003080160A1 (fr) *	2002-03-18	2003-10-02	Eli Lilly And Company	Appareil de distribution de medicament dote d'un train d'engrenages apportant un avantage technique
US6945961B2 (en) *	2002-07-10	2005-09-20	Novo Nordisk A/S	Injection device
AU2003239785A1 (en) *	2002-07-10	2004-02-02	Novo Nordisk A/S	An injection device with a dose setting limiter
RU2234882C1 (ru) *	2003-01-30	2004-08-27	Рисованная Ольга Николаевна	Инъектор
GB0304823D0 (en) *	2003-03-03	2003-04-09	Dca Internat Ltd	Improvements in and relating to a pen-type injector
EP1732629B1 (fr) *	2004-03-30	2019-04-24	Eli Lilly And Company	Appareil d'administration de medicament comprenant une caracteristique de verrouillage au moyen d'un ressort pour l'administration d'une dose finale
ATE526052T1 (de) *	2004-03-30	2011-10-15	Lilly Co Eli	Medikationsabgabegerät mit getriebeset mit einer öffnung zur aufnahme eines antriebselements
EP1923083A1 (fr) *	2006-11-17	2008-05-21	Sanofi-Aventis Deutschland GmbH	Mécanismes d'entraînement destinés à être utilisés dans des dispositifs d'administration de médicaments

2006
- 2006-11-17 EP EP20060023951 patent/EP1923083A1/fr not_active Ceased
2007
- 2007-11-08 DK DK07819685.4T patent/DK2081622T3/en active
- 2007-11-08 ES ES07819683T patent/ES2401354T3/es active Active
- 2007-11-08 CA CA 2669379 patent/CA2669379C/fr not_active Expired - Fee Related
- 2007-11-08 AU AU2007321449A patent/AU2007321449B2/en not_active Ceased
- 2007-11-08 ME MEP2909 patent/ME00589A/xx unknown
- 2007-11-08 JP JP2009536638A patent/JP5286275B2/ja not_active Expired - Fee Related
- 2007-11-08 WO PCT/EP2007/009676 patent/WO2008058668A1/fr not_active Ceased
- 2007-11-08 EP EP20110179652 patent/EP2392372A3/fr not_active Withdrawn
- 2007-11-08 KR KR1020097012438A patent/KR101422056B1/ko not_active Expired - Fee Related
- 2007-11-08 AU AU2007321447A patent/AU2007321447B9/en not_active Ceased
- 2007-11-08 WO PCT/EP2007/009674 patent/WO2008058666A1/fr not_active Ceased
- 2007-11-08 MX MX2009005093A patent/MX2009005093A/es active IP Right Grant
- 2007-11-08 PL PL07819683T patent/PL2091599T3/pl unknown
- 2007-11-08 SI SI200731179T patent/SI2091599T1/sl unknown
- 2007-11-08 BR BRPI0719069-7A2A patent/BRPI0719069A2/pt not_active IP Right Cessation
- 2007-11-08 MX MX2009005007A patent/MX2009005007A/es active IP Right Grant
- 2007-11-08 EP EP07819685.4A patent/EP2081622B1/fr active Active
- 2007-11-08 DK DK07819683T patent/DK2091599T3/da active
- 2007-11-08 RU RU2009122952/14A patent/RU2460546C2/ru not_active IP Right Cessation
- 2007-11-08 JP JP2009536636A patent/JP5427607B2/ja not_active Expired - Fee Related
- 2007-11-08 NZ NZ577007A patent/NZ577007A/en not_active IP Right Cessation
- 2007-11-08 PT PT07819683T patent/PT2091599E/pt unknown
- 2007-11-08 UA UAA200906276A patent/UA96167C2/ru unknown
- 2007-11-08 MY MYPI20091858 patent/MY148971A/en unknown
- 2007-11-08 CA CA 2669374 patent/CA2669374C/fr not_active Expired - Fee Related
- 2007-11-08 CN CN2007800498439A patent/CN101622023B/zh not_active Expired - Fee Related
- 2007-11-08 RU RU2009123008/14A patent/RU2452521C2/ru not_active IP Right Cessation
- 2007-11-08 EP EP20070819683 patent/EP2091599B1/fr active Active
- 2007-11-08 KR KR1020097012440A patent/KR101422459B1/ko not_active Expired - Fee Related
- 2007-11-08 CN CN2007800498265A patent/CN101610804B/zh not_active Expired - Fee Related
- 2007-11-08 UA UAA200906275A patent/UA97260C2/ru unknown
- 2007-11-08 BR BRPI0719070-0A2A patent/BRPI0719070A2/pt not_active IP Right Cessation
- 2007-11-08 NZ NZ576964A patent/NZ576964A/en not_active IP Right Cessation
- 2007-11-08 MY MYPI20091839 patent/MY149575A/en unknown
- 2007-11-15 PE PE2007001590A patent/PE20081203A1/es not_active Application Discontinuation
- 2007-11-15 TW TW96143136A patent/TW200833387A/zh unknown
- 2007-11-15 UY UY30721A patent/UY30721A1/es unknown
- 2007-11-15 UY UY30722A patent/UY30722A1/es unknown
- 2007-11-15 PE PE2007001591A patent/PE20081204A1/es not_active Application Discontinuation
- 2007-11-15 AR ARP070105080 patent/AR063836A1/es unknown
- 2007-11-15 TW TW096143140A patent/TWI487544B/zh not_active IP Right Cessation
- 2007-11-15 AR ARP070105079 patent/AR063830A1/es unknown
- 2007-11-16 CL CL2007003300A patent/CL2007003300A1/es unknown
- 2007-11-16 CL CL2007003301A patent/CL2007003301A1/es unknown
2009
- 2009-05-05 ZA ZA200903077A patent/ZA200903077B/xx unknown
- 2009-05-06 CR CR10770A patent/CR10770A/es not_active Application Discontinuation
- 2009-05-06 ZA ZA200903129A patent/ZA200903129B/xx unknown
- 2009-05-06 CR CR10769A patent/CR10769A/es unknown
- 2009-05-12 MA MA31865A patent/MA30884B1/fr unknown
- 2009-05-12 MA MA31866A patent/MA30885B1/fr unknown
- 2009-05-13 CO CO09048548A patent/CO6210736A2/es active IP Right Grant
- 2009-05-13 CO CO09048547A patent/CO6210737A2/es active IP Right Grant
- 2009-05-14 EG EG2009050713A patent/EG25189A/xx active
- 2009-05-14 NI NI200900087A patent/NI200900087A/es unknown
- 2009-05-14 IL IL198747A patent/IL198747A/en not_active IP Right Cessation
- 2009-05-14 IL IL198750A patent/IL198750A/en not_active IP Right Cessation
- 2009-05-15 TN TNP2009000192A patent/TN2009000192A1/fr unknown
- 2009-05-15 TN TNP2009000188A patent/TN2009000188A1/fr unknown
- 2009-05-15 HN HN2009001000A patent/HN2009001000A/es unknown
- 2009-05-15 EC ECSP099334 patent/ECSP099334A/es unknown
- 2009-05-15 EC ECSP099333 patent/ECSP099333A/es unknown
- 2009-05-15 HN HN2009000998A patent/HN2009000998A/es unknown
- 2009-05-15 US US12/466,596 patent/US7993301B2/en active Active
- 2009-05-15 GT GT200900131A patent/GT200900131A/es unknown
- 2009-05-15 US US12/466,586 patent/US8167849B2/en active Active
- 2009-05-15 GT GT200900132A patent/GT200900132A/es unknown
- 2009-05-15 SV SV2009003263A patent/SV2009003263A/es unknown
- 2009-05-15 SV SV2009003264A patent/SV2009003264A/es unknown
- 2009-05-28 NI NI200900105A patent/NI200900105A/es unknown
- 2009-06-16 NO NO20092322A patent/NO20092322L/no not_active Application Discontinuation
- 2009-06-16 NO NO20092324A patent/NO20092324L/no not_active Application Discontinuation
2011
- 2011-06-30 US US13/173,445 patent/US8771239B2/en active Active
2012
- 2012-01-10 US US13/347,399 patent/US9078976B2/en active Active
2013
- 2013-03-13 CY CY20131100219T patent/CY1113800T1/el unknown

Also Published As

Publication number	Publication date
CA2669374C (fr)	2015-03-31
CL2007003300A1 (es)	2008-06-27
RU2460546C2 (ru)	2012-09-10
US8167849B2 (en)	2012-05-01
TW200833383A (en)	2008-08-16
US7993301B2 (en)	2011-08-09
RU2452521C2 (ru)	2012-06-10
TN2009000192A1 (en)	2010-10-18
KR20090082489A (ko)	2009-07-30
AR063836A1 (es)	2009-02-25
ES2401354T3 (es)	2013-04-18
NZ577007A (en)	2011-05-27
ZA200903129B (en)	2010-03-31
PE20081204A1 (es)	2008-09-29
US8771239B2 (en)	2014-07-08
ZA200903077B (en)	2010-04-28
EP2392372A3 (fr)	2012-03-07
UA97260C2 (ru)	2012-01-25
TWI487544B (zh)	2015-06-11
CR10770A (es)	2009-07-23
DK2091599T3 (da)	2013-03-25
EP1923083A1 (fr)	2008-05-21
NI200900105A (es)	2010-01-29
IL198750A0 (en)	2010-02-17
ECSP099333A (es)	2009-06-30
IL198747A0 (en)	2010-02-17
US20120172816A1 (en)	2012-07-05
BRPI0719070A2 (pt)	2014-08-12
US9078976B2 (en)	2015-07-14
EP2081622A1 (fr)	2009-07-29
MA30885B1 (fr)	2009-11-02
IL198747A (en)	2012-12-31
CA2669374A1 (fr)	2008-05-22
RU2009123008A (ru)	2010-12-27
MX2009005007A (es)	2009-05-20
HK1140154A1 (en)	2010-10-08
NO20092322L (no)	2009-08-10
AR063830A1 (es)	2009-02-18
EP2091599A1 (fr)	2009-08-26
WO2008058666A1 (fr)	2008-05-22
NO20092324L (no)	2009-08-12
US20120289929A1 (en)	2012-11-15
GT200900132A (es)	2011-08-08
AU2007321447B9 (en)	2013-02-28
CO6210736A2 (es)	2010-10-20
ECSP099334A (es)	2009-06-30
GT200900131A (es)	2011-05-25
UY30722A1 (es)	2008-07-03
CN101622023A (zh)	2010-01-06
PT2091599E (pt)	2013-03-05
NI200900087A (es)	2010-01-29
CN101622023B (zh)	2013-04-24
DK2081622T3 (en)	2016-04-11
HN2009000998A (es)	2011-10-12
HN2009001000A (es)	2012-09-21
MX2009005093A (es)	2009-05-27
MY148971A (en)	2013-06-28
RU2009122952A (ru)	2010-12-27
US20100094207A1 (en)	2010-04-15
JP2010522577A (ja)	2010-07-08
CL2007003301A1 (es)	2008-06-27
AU2007321449B2 (en)	2013-08-22
SI2091599T1 (sl)	2013-04-30
EP2081622B1 (fr)	2016-01-06
KR101422459B1 (ko)	2014-07-23
HK1140436A1 (en)	2010-10-15
CR10769A (es)	2009-05-25
AU2007321447B2 (en)	2013-02-21
CN101610804A (zh)	2009-12-23
JP5427607B2 (ja)	2014-02-26
KR101422056B1 (ko)	2014-07-23
CY1113800T1 (el)	2016-07-27
MA30884B1 (fr)	2009-11-02
MY149575A (en)	2013-09-13
AU2007321447A1 (en)	2008-05-22
AU2007321449A1 (en)	2008-05-22
CN101610804B (zh)	2012-12-12
ME00589A (en)	2011-12-20
EP2392372A2 (fr)	2011-12-07
PE20081203A1 (es)	2008-09-24
TN2009000188A1 (en)	2010-10-18
UA96167C2 (ru)	2011-10-10
CO6210737A2 (es)	2010-10-20
SV2009003263A (es)	2009-10-27
BRPI0719069A2 (pt)	2013-12-03
KR20090080560A (ko)	2009-07-24
UY30721A1 (es)	2008-07-03
WO2008058668A1 (fr)	2008-05-22
CA2669379C (fr)	2014-12-30
SV2009003264A (es)	2009-10-27
US20100094206A1 (en)	2010-04-15
EP2091599B1 (fr)	2012-12-26
JP2010509958A (ja)	2010-04-02
IL198750A (en)	2012-10-31
JP5286275B2 (ja)	2013-09-11
PL2091599T3 (pl)	2013-07-31
EG25189A (en)	2011-10-17
NZ576964A (en)	2011-05-27
TW200833387A (en)	2008-08-16

Publication	Publication Date	Title
CA2669379C (fr)	2014-12-30	Ameliorations apportees et associees a des mecanismes d'entrainement a utiliser dans des dispositifs de distribution de medicament
US8226631B2 (en)	2012-07-24	Drive mechanisms suitable for use in drug delivery devices
CA2669363C (fr)	2016-03-22	Mecanisme de dosage et d'entrainement pour dispositif de distribution de medicament
HK1140154B (en)	2013-08-30	Improvements in and relating to drive mechanisms suitable for use in drug delivery devices
HK1138527B (en)	2014-03-14	Dosing and drive mechanism for drug delivery device

Legal Events

Date	Code	Title	Description
2012-09-27	EEER	Examination request
2016-12-20	MKLA	Lapsed	Effective date: 20161108