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CA2595783A1 - Compositions d'administration de vaccins et procedes d'utilisation associes - Google Patents

Compositions d'administration de vaccins et procedes d'utilisation associes Download PDF

Info

Publication number
CA2595783A1
CA2595783A1 CA002595783A CA2595783A CA2595783A1 CA 2595783 A1 CA2595783 A1 CA 2595783A1 CA 002595783 A CA002595783 A CA 002595783A CA 2595783 A CA2595783 A CA 2595783A CA 2595783 A1 CA2595783 A1 CA 2595783A1
Authority
CA
Canada
Prior art keywords
composition
polymer
alkyl
substituted
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002595783A
Other languages
English (en)
Inventor
William G. Tunell
Vassil P. Vassilev
Kristin M. Defife
Hong Li
Zaza D. Gomurashvili
Ramaz Katsarava
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medivas LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2595783A1 publication Critical patent/CA2595783A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G23/00—Compounds of titanium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/595—Polyamides, e.g. nylon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Environmental & Geological Engineering (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Geology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Manufacturing & Machinery (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CA002595783A 2005-02-01 2006-01-31 Compositions d'administration de vaccins et procedes d'utilisation associes Abandoned CA2595783A1 (fr)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US64928905P 2005-02-01 2005-02-01
US60/649,289 2005-02-01
US68757005P 2005-06-03 2005-06-03
US60/687,570 2005-06-03
US68900305P 2005-06-08 2005-06-08
US60/689,003 2005-06-08
US71995005P 2005-09-22 2005-09-22
US60/719,950 2005-09-22
US74218805P 2005-12-02 2005-12-02
US60/742,188 2005-12-02
US74848605P 2005-12-07 2005-12-07
US60/748,486 2005-12-07
US75917906P 2006-01-13 2006-01-13
US60/759,179 2006-01-13
PCT/US2006/003412 WO2006083874A2 (fr) 2005-02-01 2006-01-31 Compositions d'administration de vaccins et procedes d'utilisation associes

Publications (1)

Publication Number Publication Date
CA2595783A1 true CA2595783A1 (fr) 2006-08-10

Family

ID=36777844

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002595783A Abandoned CA2595783A1 (fr) 2005-02-01 2006-01-31 Compositions d'administration de vaccins et procedes d'utilisation associes

Country Status (6)

Country Link
EP (1) EP1865983A2 (fr)
JP (1) JP2008532929A (fr)
KR (1) KR20070101341A (fr)
AU (1) AU2006210863A1 (fr)
CA (1) CA2595783A1 (fr)
WO (1) WO2006083874A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060177416A1 (en) 2003-10-14 2006-08-10 Medivas, Llc Polymer particle delivery compositions and methods of use
EP1926780B1 (fr) 2005-09-22 2013-08-14 Medivas, LLC Formules de poly(ester amide) et de poly(ester uréthane) contenant des diesters de bis-( -amino)-diol et méthodes d'emploi
US8652504B2 (en) 2005-09-22 2014-02-18 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
EP1957113A4 (fr) * 2005-11-21 2011-11-09 Medivas Llc Particules polymeriques pour administration de macromolecules et procedes d'utilisation
WO2007089870A2 (fr) * 2006-01-31 2007-08-09 Medivas, Llc Compositions des modes d'administration d'un vaccin et procedes d'utilisation
AU2007340343A1 (en) * 2006-09-05 2008-07-10 Medivas, Llc Polymer-stabilized liposomal compositions and methods of use
EP2017006A1 (fr) 2007-07-20 2009-01-21 Koninklijke Philips Electronics N.V. Procédés microfluidiques et systèmes servant à détecter des analytes
EP2262480B1 (fr) * 2008-03-04 2018-02-14 Liquidia Technologies, Inc. Particules immunomodulatrices
JP2011523669A (ja) * 2008-05-07 2011-08-18 メディバス エルエルシー 生分解性金属キレート化ポリマーおよびワクチン
EP2404618A1 (fr) 2010-07-07 2012-01-11 Stichting Katholieke Universiteit meer in het bijzonder Radboud Universiteit Nijmegen Configuration de protéine immunomodulatoire avec un polymer à squelette hélicale
KR101327181B1 (ko) * 2011-02-28 2013-11-06 이연제약주식회사 신장세포특이적인 펩타이드 및 폴리에스테르아민 중합체를 포함하는 유전자 전달체 및 이를 포함한 신장 섬유증 예방 또는 치료용 조성물.
CA2839526A1 (fr) 2011-06-23 2012-12-27 Dsm Ip Assets B.V. Microparticules ou nanoparticules comprenant un copolymere biodegradable de polyesteramide destinees a une utilisation dans l'administration d'agents bioactifs
US9873765B2 (en) 2011-06-23 2018-01-23 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
EP3233067B1 (fr) 2014-12-18 2019-11-06 DSM IP Assets B.V. Système d'administration de médicament pour délivrer des médicaments sensibles à l'acide
WO2016176761A1 (fr) * 2015-05-01 2016-11-10 Immunovaccine Technologies Inc., Méthodes de potentialisation d'une réponse immunitaire utilisant des vaccins formant un site tissulaire de stockage et des vaccins n'en formant pas
BR112019020853A2 (pt) 2017-04-04 2020-05-12 Avidea Technologies, Inc. Vacinas à base de peptídeo, métodos de fabricação e usos das mesmas para induzir uma resposta imune
US20210113705A1 (en) * 2018-05-22 2021-04-22 Avidea Technologies, Inc. Improved methods of manufacturing peptide-based vaccines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6503538B1 (en) * 2000-08-30 2003-01-07 Cornell Research Foundation, Inc. Elastomeric functional biodegradable copolyester amides and copolyester urethanes

Also Published As

Publication number Publication date
AU2006210863A1 (en) 2006-08-10
KR20070101341A (ko) 2007-10-16
WO2006083874A2 (fr) 2006-08-10
WO2006083874A3 (fr) 2009-04-23
JP2008532929A (ja) 2008-08-21
EP1865983A2 (fr) 2007-12-19

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Legal Events

Date Code Title Description
FZDE Discontinued