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CA2592330A1 - Anticorps anti-gitr pour le diagnostic du cancer du poumon non a petites cellules (cpnpc) - Google Patents

Anticorps anti-gitr pour le diagnostic du cancer du poumon non a petites cellules (cpnpc) Download PDF

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Publication number
CA2592330A1
CA2592330A1 CA002592330A CA2592330A CA2592330A1 CA 2592330 A1 CA2592330 A1 CA 2592330A1 CA 002592330 A CA002592330 A CA 002592330A CA 2592330 A CA2592330 A CA 2592330A CA 2592330 A1 CA2592330 A1 CA 2592330A1
Authority
CA
Canada
Prior art keywords
antibody
gene
cell
antibodies
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002592330A
Other languages
English (en)
Inventor
Beverly Teicher
Srinivas Shankara
Bruce Roberts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genzyme Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2592330A1 publication Critical patent/CA2592330A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002592330A 2005-01-19 2006-01-19 Anticorps anti-gitr pour le diagnostic du cancer du poumon non a petites cellules (cpnpc) Abandoned CA2592330A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64534905P 2005-01-19 2005-01-19
US60/645,349 2005-01-19
PCT/US2006/002050 WO2006078911A2 (fr) 2005-01-19 2006-01-19 Anticorps anti-gitr pour le diagnostic du cancer du poumon non a petites cellules (cpnpc)

Publications (1)

Publication Number Publication Date
CA2592330A1 true CA2592330A1 (fr) 2006-07-27

Family

ID=36692925

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002592330A Abandoned CA2592330A1 (fr) 2005-01-19 2006-01-19 Anticorps anti-gitr pour le diagnostic du cancer du poumon non a petites cellules (cpnpc)

Country Status (8)

Country Link
EP (1) EP1856281A2 (fr)
JP (1) JP2008527998A (fr)
CN (1) CN101133167A (fr)
AU (1) AU2006206343A1 (fr)
BR (1) BRPI0606685A2 (fr)
CA (1) CA2592330A1 (fr)
IL (1) IL184343A0 (fr)
WO (1) WO2006078911A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2602777C (fr) 2005-03-25 2018-12-11 Tolerrx, Inc. Molecules de liaison gitr et leurs utilisations
DK2175884T3 (en) 2007-07-12 2016-09-26 Gitr Inc Combination USING GITR BINDING MOLECULES
SG178991A1 (en) 2009-09-03 2012-04-27 Schering Corp Anti-gitr antibodies
KR101566538B1 (ko) 2012-06-08 2015-11-05 국립암센터 신규한 Th17 세포 전환용 에피토프 및 이의 용도
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
CA2951234C (fr) 2014-06-06 2022-05-31 Bristol-Myers Squibb Company Anticorps anti recepteur du facteur de necrose tumorale induit par glucocorticoides (gitr) et leurs utilisations
JP5995207B2 (ja) * 2014-11-28 2016-09-21 学校法人 学習院 含ホウ素ポルフィリン誘導体
US10690674B2 (en) 2015-06-03 2020-06-23 Bristol-Myers Squibb Company Anti-GITR antibodies for cancer diagnostics
AU2016356780A1 (en) 2015-11-19 2018-06-28 Bristol-Myers Squibb Company Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
WO2017156058A1 (fr) * 2016-03-08 2017-09-14 Janssen Biotech, Inc. Anticorps anti-gitr, méthodes et utilisations
CN118497192A (zh) * 2017-03-07 2024-08-16 豪夫迈·罗氏有限公司 发现替代性抗原特异性抗体变体的方法
CN110869392A (zh) 2017-05-16 2020-03-06 百时美施贵宝公司 用抗gitr激动性抗体治疗癌症
CN109777872B (zh) * 2017-11-15 2021-04-02 北京大学 肺癌中的t细胞亚群及其特征基因

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030138426A1 (en) * 1997-10-21 2003-07-24 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like proteins TR11, TR11SV1, and TR11SV2
US6689607B2 (en) * 1997-10-21 2004-02-10 Human Genome Sciences, Inc. Human tumor, necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2
JP2001520039A (ja) * 1997-10-21 2001-10-30 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド ヒト腫瘍壊死因子レセプター様タンパク質、tr11,tr11sv1およびtr11sv2
US6503184B1 (en) * 1997-10-21 2003-01-07 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2
WO2000050459A1 (fr) * 1999-02-24 2000-08-31 Human Genome Sciences, Inc. Proteines tr11, tr11sv1, et tr11sv2 du type recepteur tnf humain
AU2004245998A1 (en) * 2003-06-04 2004-12-16 The Government of the United States as represented by The Secretary of the Department of Health and Human Services, Centres for Disease Control and Prevention PNI microarray and uses

Also Published As

Publication number Publication date
BRPI0606685A2 (pt) 2009-07-14
AU2006206343A1 (en) 2006-07-27
WO2006078911A2 (fr) 2006-07-27
IL184343A0 (en) 2007-10-31
EP1856281A2 (fr) 2007-11-21
JP2008527998A (ja) 2008-07-31
CN101133167A (zh) 2008-02-27
WO2006078911A3 (fr) 2007-06-28

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Legal Events

Date Code Title Description
FZDE Discontinued