CA2573150A1 - Imagerie et detection biologique par fluorescence au moyen de nanocristaux semi-conducteurs stables dans l'eau - Google Patents

Imagerie et detection biologique par fluorescence au moyen de nanocristaux semi-conducteurs stables dans l'eau Download PDF

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Publication number: CA2573150A1
Authority: CA; Canada
Prior art keywords: complex; light; target; biological molecule; semiconductor nanocrystal
Prior art date: 2004-07-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002573150A

Other languages

English (en)

Inventor

Wei Liu

Zuoyan Peng

Michael Locascio

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Evident Technologies Inc

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-07-08

Filing date

2005-07-08

Publication date

2006-02-09

2004-07-08 Priority claimed from US10/885,867 external-priority patent/US7192780B2/en

2005-07-08 Application filed by Individual filed Critical Individual

2006-02-09 Publication of CA2573150A1 publication Critical patent/CA2573150A1/fr

Status Abandoned legal-status Critical Current

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QJHBJHUKURJDLG-UHFFFAOYSA-N hydroxy-L-lysine Natural products NCCCCC(NO)C(O)=O QJHBJHUKURJDLG-UHFFFAOYSA-N 0.000 description 1
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150000002632 lipids Chemical class 0.000 description 1
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235000019136 lipoic acid Nutrition 0.000 description 1
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GMKMEZVLHJARHF-SYDPRGILSA-N meso-2,6-diaminopimelic acid Chemical compound [O-]C(=O)[C@@H]([NH3+])CCC[C@@H]([NH3+])C([O-])=O GMKMEZVLHJARHF-SYDPRGILSA-N 0.000 description 1
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WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
210000005036 nerve Anatomy 0.000 description 1
150000002825 nitriles Chemical class 0.000 description 1
QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
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ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
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210000003705 ribosome Anatomy 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
SBIBMFFZSBJNJF-UHFFFAOYSA-N selenium;zinc Chemical compound [Se]=[Zn] SBIBMFFZSBJNJF-UHFFFAOYSA-N 0.000 description 1
238000001338 self-assembly Methods 0.000 description 1
238000000926 separation method Methods 0.000 description 1
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159000000000 sodium salts Chemical class 0.000 description 1
238000004611 spectroscopical analysis Methods 0.000 description 1
150000003408 sphingolipids Chemical class 0.000 description 1
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ZPXYTWHLXRHOPX-UHFFFAOYSA-N sulfanyloxymethanethioic s-acid Chemical compound SOC(S)=O ZPXYTWHLXRHOPX-UHFFFAOYSA-N 0.000 description 1
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OCGWQDWYSQAFTO-UHFFFAOYSA-N tellanylidenelead Chemical compound [Pb]=[Te] OCGWQDWYSQAFTO-UHFFFAOYSA-N 0.000 description 1
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Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Analytical Chemistry (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Pathology (AREA)
General Physics & Mathematics (AREA)
Hematology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Physics & Mathematics (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Nanotechnology (AREA)
Crystallography & Structural Chemistry (AREA)
Microbiology (AREA)
Materials Engineering (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

CA002573150A 2004-07-08 2005-07-08 Imagerie et detection biologique par fluorescence au moyen de nanocristaux semi-conducteurs stables dans l'eau Abandoned CA2573150A1 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US10/885,867 US7192780B2 (en)	2002-10-23	2004-07-08	Fluorescent lifetime biological detection and imaging using water-stable semiconductor nanocrystals
US10/885,867		2004-07-08
PCT/US2005/024211 WO2006014576A2 (fr)	2002-10-23	2005-07-08	Imagerie et detection biologique par fluorescence au moyen de nanocristaux semi-conducteurs stables dans l'eau

Publications (1)

Publication Number	Publication Date
CA2573150A1 true CA2573150A1 (fr)	2006-02-09

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ID=37872031

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002573150A Abandoned CA2573150A1 (fr)	2004-07-08	2005-07-08	Imagerie et detection biologique par fluorescence au moyen de nanocristaux semi-conducteurs stables dans l'eau

Country Status (2)

Country	Link
EP (1)	EP1784502A4 (fr)
CA (1)	CA2573150A1 (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6872450B2 (en) *	2002-10-23	2005-03-29	Evident Technologies	Water-stable photoluminescent semiconductor nanocrystal complexes and method of making same

2005
- 2005-07-08 EP EP05769351A patent/EP1784502A4/fr not_active Withdrawn
- 2005-07-08 CA CA002573150A patent/CA2573150A1/fr not_active Abandoned

Also Published As

Publication number	Publication date
EP1784502A2 (fr)	2007-05-16
EP1784502A4 (fr)	2007-10-03

Publication	Publication Date	Title
US6872450B2 (en)	2005-03-29	Water-stable photoluminescent semiconductor nanocrystal complexes and method of making same
Riegler et al.	2004	Application of luminescent nanocrystals as labels for biological molecules
US7214428B2 (en)	2007-05-08	Highly luminescent functionalized semiconductor nanocrystals for biological and physical applications
US7368086B2 (en)	2008-05-06	Functionalized fluorescent nanocrystals, and methods for their preparation and use
Cognet et al.	2008	Photothermal methods for single nonluminescent nano-objects
US7205048B2 (en)	2007-04-17	Functionalized fluorescent nanocrystal compositions and methods of making
US8425858B2 (en)	2013-04-23	Detection apparatus and associated method
US7192780B2 (en)	2007-03-20	Fluorescent lifetime biological detection and imaging using water-stable semiconductor nanocrystals
US8815158B2 (en)	2014-08-26	Granular nanoparticles having bright fluorescence and giant raman enhancements
CN107787352A (zh)	2018-03-09	连续发射的核/壳纳米片
US12399124B2 (en)	2025-08-26	Ultra-sensitive detection method using photoluminescent particles
Chong et al.	2007	Development of FRET‐Based Assays in the Far‐Red Using CdTe Quantum Dots
EP2769403B1 (fr)	2020-01-08	Biomarqueurs améliorés et utilisation de ces derniers
CA2573150A1 (fr)	2006-02-09	Imagerie et detection biologique par fluorescence au moyen de nanocristaux semi-conducteurs stables dans l'eau
Bruchez Jr	1998	Luminescent semiconductor nanocrystals: Intermittent behavior and use as fluorescent biological probes
US20070003948A1 (en)	2007-01-04	Semiconductor nanocrystal complexes and methods of detecting molecular interactions using same
KR100878980B1 (ko)	2009-01-14	Ｄｎａ에 결합된 염료 수용체와 ｑｄ 공여체로 구성된신규한 ｆｒｅｔ 시스템
Comparelli et al.	2007	Optical biosensing based on metal and semiconductor colloidal nanocrystals
Pompa et al.	2009	Fluorescent Nanocrystals and Proteins
Chan et al.	2004	and Ultrasensitive Biological Labels
Huser et al.	2003	SYMPOSIUM AA
Wang et al.	2006	Quantitative doping of commercial polystyrene microbeads with quantum dots
Cognet et al.	0	New optical methods allow the detection of tiny individual nano-objects, opening a wide range of applications.

Legal Events

Date	Code	Title	Description
2011-07-08	FZDE	Discontinued