CA2561221A1 - Modulateurs d'interference d'arn de signalisation hedgehog et leurs utilisations - Google Patents
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| CA (1) | CA2561221C (fr) |
| DK (1) | DK1730280T3 (fr) |
| ES (1) | ES2707393T3 (fr) |
| WO (1) | WO2005097207A2 (fr) |
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| WO2006078278A2 (fr) | 2004-04-27 | 2006-07-27 | Alnylam Pharmaceuticals, Inc. | Oligonucleotides mono-brin et double brin a fraction 2-arylpropyle |
| AU2005323437B2 (en) | 2004-04-30 | 2011-10-06 | Alnylam Pharmaceuticals, Inc. | Oligonucleotides comprising a C5-modified pyrimidine |
| WO2006088490A2 (fr) | 2004-06-30 | 2006-08-24 | Alnylam Pharmaceuticals, Inc. | Oligonucleotides comprenant une liaison de squelette non-phosphate |
| US7579451B2 (en) * | 2004-07-21 | 2009-08-25 | Alnylam Pharmaceuticals, Inc. | Oligonucleotides comprising a modified or non-natural nucleobase |
| WO2006112872A2 (fr) | 2004-08-04 | 2006-10-26 | Alnylam Pharmaceuticals, Inc. | Oligonucleotides comprenant un ligand attache a une nucleobase modifiee ou non naturelle |
| WO2006031977A2 (fr) * | 2004-09-13 | 2006-03-23 | The Regents Of The University Of California | Inhibition de la croissance des cellules de cancer du pancreas |
| US7517870B2 (en) * | 2004-12-03 | 2009-04-14 | Fondazione Telethon | Use of compounds that interfere with the hedgehog signaling pathway for the manufacture of a medicament for preventing, inhibiting, and/or reversing ocular diseases related with ocular neovascularization |
| EP1838853A2 (fr) * | 2005-01-06 | 2007-10-03 | Benitec, Inc. | Agents arni pour l'entretien de cellules souches |
| US7714014B2 (en) * | 2005-12-09 | 2010-05-11 | The Regents Of The University Of California | Targeting GLI proteins in human cancer by small molecules |
| US8142388B2 (en) * | 2006-10-30 | 2012-03-27 | Gomez Mario P | Apparatus to facilitate removal of cataracts of from the eyes |
| AU2008345246B2 (en) * | 2007-12-28 | 2014-08-07 | Genentech, Inc. | Anti-hedgehog antibodies |
| US8252823B2 (en) * | 2008-01-28 | 2012-08-28 | New York University | Oxazole and thiazole compounds as beta-catenin modulators and uses thereof |
| US9173871B2 (en) | 2008-01-28 | 2015-11-03 | New York University | Oxazole and thiazole compounds as beta-catenin modulators and uses thereof |
| US9874553B2 (en) | 2008-09-10 | 2018-01-23 | New York University | Targeted chemical high-throughput screening method |
| US20100112042A1 (en) * | 2008-10-16 | 2010-05-06 | Mdrna, Inc. | Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics |
| IT1398977B1 (it) | 2009-06-25 | 2013-03-28 | Icgeb | Agente anticancro specifico per i tumori cerebrali con meccanismo di soppressione di recq1 |
| EP2407173A1 (fr) * | 2010-07-13 | 2012-01-18 | Netris Pharma | Procédé et compositions pour induire l'apoptose de cellules tumorales exprimant le gène SHH |
| US20120252870A1 (en) * | 2011-02-19 | 2012-10-04 | Rhode Island Hospital | Indian Hedgehog (Ihh) as a Marker to Predict Osteoarthritis (OA) and Methods for the Prevention and Treatment of OA |
| WO2015073691A1 (fr) | 2013-11-14 | 2015-05-21 | The Board Of Trustees Of The Leland Stanford Junior University | Procédés pour traiter le cancer par activation de la signalisation bmp |
| US20160082162A1 (en) * | 2014-09-19 | 2016-03-24 | Board of Education of the Vocational Schools in the County of Bergen | Nanoparticle-Medicated Genetic Delivery of Growth Inhibiting Genes on Balloon Angioplasty to Suppress Intimal Hyperplasia |
| EP3400307A1 (fr) * | 2016-01-08 | 2018-11-14 | Abbott Molecular Inc. | Tampons d'hybridation comprenant du thiocyanate de guanidinium |
| US10548908B2 (en) | 2016-09-15 | 2020-02-04 | Nostopharma, LLC | Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification |
| EP3981431A4 (fr) * | 2019-03-14 | 2023-06-28 | Rena Therapeutics Inc. | Complexe d'acide nucléique pour moduler l'expression d'ihh |
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-
2005
- 2005-03-23 ES ES05732497T patent/ES2707393T3/es not_active Expired - Lifetime
- 2005-03-23 WO PCT/US2005/009739 patent/WO2005097207A2/fr not_active Ceased
- 2005-03-23 CA CA2561221A patent/CA2561221C/fr not_active Expired - Fee Related
- 2005-03-23 EP EP05732497.2A patent/EP1730280B1/fr not_active Expired - Lifetime
- 2005-03-23 JP JP2007505149A patent/JP5184077B2/ja not_active Expired - Fee Related
- 2005-03-23 AU AU2005231692A patent/AU2005231692B2/en not_active Ceased
- 2005-03-23 DK DK05732497.2T patent/DK1730280T3/en active
- 2005-03-24 US US11/088,691 patent/US8802639B2/en not_active Expired - Fee Related
-
2011
- 2011-04-27 AU AU2011201901A patent/AU2011201901A1/en not_active Abandoned
-
2012
- 2012-01-20 JP JP2012010375A patent/JP2012116845A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK1730280T3 (en) | 2019-02-04 |
| AU2005231692B2 (en) | 2011-01-27 |
| ES2707393T3 (es) | 2019-04-03 |
| JP2007530571A (ja) | 2007-11-01 |
| WO2005097207A3 (fr) | 2006-01-12 |
| EP1730280A2 (fr) | 2006-12-13 |
| EP1730280B1 (fr) | 2018-10-24 |
| AU2005231692A1 (en) | 2005-10-20 |
| US20050256076A1 (en) | 2005-11-17 |
| JP5184077B2 (ja) | 2013-04-17 |
| CA2561221C (fr) | 2016-09-20 |
| US8802639B2 (en) | 2014-08-12 |
| WO2005097207A2 (fr) | 2005-10-20 |
| JP2012116845A (ja) | 2012-06-21 |
| AU2011201901A1 (en) | 2011-05-19 |
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