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CA2438740A1 - Enzymes metabolisant un medicament - Google Patents

Enzymes metabolisant un medicament Download PDF

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Publication number
CA2438740A1
CA2438740A1 CA002438740A CA2438740A CA2438740A1 CA 2438740 A1 CA2438740 A1 CA 2438740A1 CA 002438740 A CA002438740 A CA 002438740A CA 2438740 A CA2438740 A CA 2438740A CA 2438740 A1 CA2438740 A1 CA 2438740A1
Authority
CA
Canada
Prior art keywords
polynucleotide
polypeptide
seq
amino acid
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002438740A
Other languages
English (en)
Inventor
Anna Astromoff
Janice Au-Young
Mariah R. Baughn
Li Ding
Brendan M. Duggan
Ian J. Forsythe
Kimberly J. Gietzen
Jennifer A. Griffin
Ernestine A. Lee
Yan Lu
Thomas W. Richardson
Huijun Z. Ring
Madhusudan M. Sanjanwala
Anita Swarnakar
Narinder K. Chawla
Bridget A. Warren
Yuming Xu
Henry Yue
Yeggie Zebarjadian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Publication of CA2438740A1 publication Critical patent/CA2438740A1/fr
Abandoned legal-status Critical Current

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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
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    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N9/10—Transferases (2.)
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
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    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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    • C12Q2600/00—Oligonucleotides characterized by their use
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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
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Abstract

L'invention concerne des enzymes humaines métabolisant un médicament (DME) et des polynucléotides qui identifient et codent pour DME. L'invention concerne aussi des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes ; ainsi que des procédés permettant de diagnostiquer, de traiter ou de prévenir des troubles associés à une expression aberrante de DME.
CA002438740A 2001-02-16 2002-02-14 Enzymes metabolisant un medicament Abandoned CA2438740A1 (fr)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US26964301P 2001-02-16 2001-02-16
US60/269,643 2001-02-16
US27133201P 2001-02-23 2001-02-23
US60/271,332 2001-02-23
US27676701P 2001-03-16 2001-03-16
US60/276,767 2001-03-16
US28207701P 2001-04-06 2001-04-06
US60/282,077 2001-04-06
US28544701P 2001-04-19 2001-04-19
US60/285,447 2001-04-19
US28706001P 2001-04-27 2001-04-27
US60/287,060 2001-04-27
US28854301P 2001-05-03 2001-05-03
US60/288,543 2001-05-03
PCT/US2002/004918 WO2002066654A2 (fr) 2001-02-16 2002-02-14 Enzymes metabolisant un medicament

Publications (1)

Publication Number Publication Date
CA2438740A1 true CA2438740A1 (fr) 2002-08-29

Family

ID=27569536

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002438740A Abandoned CA2438740A1 (fr) 2001-02-16 2002-02-14 Enzymes metabolisant un medicament

Country Status (4)

Country Link
EP (1) EP1399564A2 (fr)
JP (1) JP2006514531A (fr)
CA (1) CA2438740A1 (fr)
WO (1) WO2002066654A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003238835A1 (en) * 2002-05-30 2003-12-19 Bristol-Myers Squibb Company HUMAN COACTIVATOR-ASSOCIATED ARGININE METHYLTRANSFERASE 1 (hCARM1)
FI20040255A7 (fi) * 2004-02-18 2005-08-19 Oy Jurilab Ltd Menetelmä pre-eklampsian riskin havaitsemiseksi
EP2816113A3 (fr) * 2008-09-11 2015-03-25 Galapagos N.V. Procédés d'identification et composés utiles pour augmenter l'activité fonctionnelle et l'expression de surface cellulaire du régulateur de la conductance de trans-membrane de la fibrose kystique mutante associée à la mucoviscidose
WO2011131626A1 (fr) * 2010-04-19 2011-10-27 Medizinische Universität Innsbruck Tmem195 code pour l'activité alkylglycérol monooxygénase dépendante de la tétrahydrobioptérine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100543857B1 (ko) * 1999-09-01 2006-01-23 제넨테크, 인크. 혈관신생 및 심혈관형성의 촉진 또는 억제

Also Published As

Publication number Publication date
EP1399564A2 (fr) 2004-03-24
WO2002066654A2 (fr) 2002-08-29
JP2006514531A (ja) 2006-05-11
WO2002066654A3 (fr) 2004-01-08

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