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CA2428979A1 - Canal potassium erg2 humain - Google Patents

Canal potassium erg2 humain Download PDF

Info

Publication number
CA2428979A1
CA2428979A1 CA002428979A CA2428979A CA2428979A1 CA 2428979 A1 CA2428979 A1 CA 2428979A1 CA 002428979 A CA002428979 A CA 002428979A CA 2428979 A CA2428979 A CA 2428979A CA 2428979 A1 CA2428979 A1 CA 2428979A1
Authority
CA
Canada
Prior art keywords
erg2
seq
protein
potassium channels
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002428979A
Other languages
English (en)
Inventor
Kimberly L. Folander
Edward J. Mckenna
Richard J. Swanson
Yuan Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2428979A1 publication Critical patent/CA2428979A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne de nouvelles séquences d'ADN humain codant des protéines h-erg2, la protéine codée par lesdites séquences d'ADN, des vecteurs comprenant lesdites séquences d'ADN, des cellules hôtes contenant lesdits vecteurs, ainsi que des procédés permettant d'identifier des inhibiteurs et des activateurs de canaux potassium contenant les protéines h-erg2.
CA002428979A 2000-11-20 2001-11-16 Canal potassium erg2 humain Abandoned CA2428979A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24998100P 2000-11-20 2000-11-20
US60/249,981 2000-11-20
PCT/US2001/043490 WO2002042417A2 (fr) 2000-11-20 2001-11-16 Canal potassium erg2 humain

Publications (1)

Publication Number Publication Date
CA2428979A1 true CA2428979A1 (fr) 2002-05-30

Family

ID=22945815

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002428979A Abandoned CA2428979A1 (fr) 2000-11-20 2001-11-16 Canal potassium erg2 humain

Country Status (4)

Country Link
EP (1) EP1517917A4 (fr)
JP (1) JP2004535760A (fr)
CA (1) CA2428979A1 (fr)
WO (1) WO2002042417A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003006679A2 (fr) * 2001-07-10 2003-01-23 Millennium Pharmaceuticals, Inc. 52908 : un canal potassique humain et utilisations de celui-ci
CN1845726A (zh) 2003-09-04 2006-10-11 波塞东医药公司 用于治疗心脏心律失常的erg通道开放剂

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5986081A (en) * 1997-10-22 1999-11-16 Wisconsin Alumni Research Foundation Polynucleotides encoding herg-3
CA2323725A1 (fr) * 1998-03-20 1999-09-23 The Rockefeller University Essais de recherche systematique de composes en interaction avec des proteines de canal cation, proteines de canal cation procaryotes mutantes, et utilisations correspondantes
AU2001273239A1 (en) * 2000-07-07 2002-01-21 Incyte Genomics, Inc. Transporters and ion channels
WO2003006679A2 (fr) * 2001-07-10 2003-01-23 Millennium Pharmaceuticals, Inc. 52908 : un canal potassique humain et utilisations de celui-ci

Also Published As

Publication number Publication date
EP1517917A4 (fr) 2005-10-12
JP2004535760A (ja) 2004-12-02
WO2002042417A3 (fr) 2005-01-27
WO2002042417A2 (fr) 2002-05-30
EP1517917A2 (fr) 2005-03-30

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Legal Events

Date Code Title Description
FZDE Discontinued