CA2423592A1 - Procedes et compositions permettant la reparation et/ou la regeneration de myocarde endommage - Google Patents
Procedes et compositions permettant la reparation et/ou la regeneration de myocarde endommage Download PDFInfo
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- CA2423592A1 CA2423592A1 CA002423592A CA2423592A CA2423592A1 CA 2423592 A1 CA2423592 A1 CA 2423592A1 CA 002423592 A CA002423592 A CA 002423592A CA 2423592 A CA2423592 A CA 2423592A CA 2423592 A1 CA2423592 A1 CA 2423592A1
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- cells
- stem cells
- hematopoietic stem
- myocardium
- heart
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- Dental Preparations (AREA)
Abstract
La présente invention concerne des procédés, compositions, et trousses pour la réparation de myocarde et/ou de cellules de myocarde endommagés comprenant l'administration de cellules-souches, telles que des cellules-souches adultes, éventuellement avec des cytokines.
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22190200P | 2000-07-31 | 2000-07-31 | |
| US60/221,902 | 2000-07-31 | ||
| US25856400P | 2000-12-29 | 2000-12-29 | |
| US60/258,564 | 2000-12-29 | ||
| US25880501P | 2001-01-02 | 2001-01-02 | |
| US60/258,805 | 2001-01-02 | ||
| PCT/US2001/024223 WO2002013760A2 (fr) | 2000-07-31 | 2001-07-31 | Procedes et compositions permettant la reparation et/ou la regeneration de myocarde endommage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2423592A1 true CA2423592A1 (fr) | 2002-02-21 |
Family
ID=27397004
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002423592A Abandoned CA2423592A1 (fr) | 2000-07-31 | 2001-07-31 | Procedes et compositions permettant la reparation et/ou la regeneration de myocarde endommage |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1315510A4 (fr) |
| AU (1) | AU2001283088A1 (fr) |
| CA (1) | CA2423592A1 (fr) |
| WO (1) | WO2002013760A2 (fr) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL159580A0 (en) | 2001-07-12 | 2004-06-01 | Geron Corp | Cells of the cardiomyocyte lineage produced from human pluripotent stem cells |
| US7732199B2 (en) | 2001-07-12 | 2010-06-08 | Geron Corporation | Process for making transplantable cardiomyocytes from human embryonic stem cells |
| WO2004011012A2 (fr) | 2002-07-29 | 2004-02-05 | Asahi Kasei Kabushiki Kaisha | Cellules declenchantes de la regeneration |
| ITRM20030376A1 (it) | 2003-07-31 | 2005-02-01 | Univ Roma | Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia. |
| US7452718B2 (en) | 2004-03-26 | 2008-11-18 | Geron Corporation | Direct differentiation method for making cardiomyocytes from human embryonic stem cells |
| US11660317B2 (en) | 2004-11-08 | 2023-05-30 | The Johns Hopkins University | Compositions comprising cardiosphere-derived cells for use in cell therapy |
| KR20130099253A (ko) | 2005-06-22 | 2013-09-05 | 제론 코포레이션 | 영장류 다능성 줄기 세포의 심근세포 계통 세포로의 분화 |
| US20110076255A1 (en) | 2005-11-07 | 2011-03-31 | Pecora Andrew L | Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency |
| US8637005B2 (en) | 2005-11-07 | 2014-01-28 | Amorcyte, Inc. | Compositions and methods of vascular injury repair |
| DK2441461T3 (da) | 2005-11-07 | 2014-07-28 | Amorcyte Inc | Sammensætninger og fremgangsmåder til reparation af vaskulær skade |
| WO2008011094A2 (fr) * | 2006-07-18 | 2008-01-24 | Robert Sackstein | Induction par la cytokine de ligands de sélectine sur des cellules |
| US8512696B2 (en) | 2007-11-30 | 2013-08-20 | Autologous, Llc | Methods of isolating non-senescent cardiac stem cells and uses thereof |
| WO2009073618A2 (fr) * | 2007-11-30 | 2009-06-11 | New York Medical College | Compositions comprenant des inhibiteurs hdac et procédés permettant de les utiliser pour réparer la fonction des cellules souches et empêcher l'insuffisance cardiaque |
| CA2743682A1 (fr) | 2007-11-30 | 2009-06-11 | New York Medical College | Procedes permettant de reduire le rejet de greffon et l'arteriosclerose acceleree du greffon cardiaque par implantation de cellules souches autologues |
| EP2227238A2 (fr) | 2007-11-30 | 2010-09-15 | New York Medical College | Compositions comprenant des cellules progénitrices vasculaires et myocytaires et procédés permettant de les utiliser |
| SG188098A1 (en) | 2008-01-30 | 2013-03-28 | Geron Corp | Synthetic surfaces for culturing stem cell derived cardiomyocytes |
| WO2010065601A1 (fr) | 2008-12-03 | 2010-06-10 | Amorcyte, Inc. | Compositions améliorant la perfusion d’une zone d’infarctus et procédés de réparation de lésion vasculaire |
| US9249392B2 (en) | 2010-04-30 | 2016-02-02 | Cedars-Sinai Medical Center | Methods and compositions for maintaining genomic stability in cultured stem cells |
| US9845457B2 (en) | 2010-04-30 | 2017-12-19 | Cedars-Sinai Medical Center | Maintenance of genomic stability in cultured stem cells |
| EP2861238A4 (fr) | 2012-06-05 | 2016-03-16 | Capricor Inc | Procédés optimisés pour générer des cellules souches cardiaques à partir de tissu cardiaque et leur utilisation dans une thérapie cardiaque |
| US9828603B2 (en) | 2012-08-13 | 2017-11-28 | Cedars Sinai Medical Center | Exosomes and micro-ribonucleic acids for tissue regeneration |
| US11357799B2 (en) | 2014-10-03 | 2022-06-14 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy |
| EP3402543B1 (fr) | 2016-01-11 | 2021-09-08 | Cedars-Sinai Medical Center | Cellules dérivées de cardiosphères et exosomes sécrétés par ces cellules dans le traitement d'une insuffisance cardiaque à fraction d'éjection préservée |
| US11351200B2 (en) | 2016-06-03 | 2022-06-07 | Cedars-Sinai Medical Center | CDC-derived exosomes for treatment of ventricular tachyarrythmias |
| EP3515459A4 (fr) | 2016-09-20 | 2020-08-05 | Cedars-Sinai Medical Center | Cellules dérivées de cardiosphères et leurs vésicules extracellulaires pour retarder ou inverser le vieillissement et des troubles liés à l'âge |
| US11759482B2 (en) | 2017-04-19 | 2023-09-19 | Cedars-Sinai Medical Center | Methods and compositions for treating skeletal muscular dystrophy |
| US11660355B2 (en) | 2017-12-20 | 2023-05-30 | Cedars-Sinai Medical Center | Engineered extracellular vesicles for enhanced tissue delivery |
| EP3749344A4 (fr) | 2018-02-05 | 2022-01-26 | Cedars-Sinai Medical Center | Procédés d'utilisation thérapeutique d'exosomes et d'arn y |
| CN118490802B (zh) * | 2024-05-31 | 2025-03-18 | 中国人民解放军海军特色医学中心 | 一种用于改善运动心肌损伤的组合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5083098A (en) * | 1996-10-25 | 1998-05-22 | Icogen Corporation | Use of leptin to stimulate hematopoiesis |
| AU5545499A (en) * | 1998-07-31 | 2000-02-21 | Genzyme Corporation | Improvement of cardiac function by mesenchymal stem cell transplantation |
-
2001
- 2001-07-31 AU AU2001283088A patent/AU2001283088A1/en not_active Abandoned
- 2001-07-31 EP EP01961855A patent/EP1315510A4/fr not_active Withdrawn
- 2001-07-31 CA CA002423592A patent/CA2423592A1/fr not_active Abandoned
- 2001-07-31 WO PCT/US2001/024223 patent/WO2002013760A2/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1315510A2 (fr) | 2003-06-04 |
| WO2002013760A2 (fr) | 2002-02-21 |
| AU2001283088A1 (en) | 2002-02-25 |
| EP1315510A4 (fr) | 2005-08-03 |
| WO2002013760A9 (fr) | 2003-09-04 |
| WO2002013760A3 (fr) | 2002-04-18 |
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