[go: up one dir, main page]

CA2421747A1 - Polymorphismes associes a l'arythmie cardiaque - Google Patents

Polymorphismes associes a l'arythmie cardiaque Download PDF

Info

Publication number
CA2421747A1
CA2421747A1 CA002421747A CA2421747A CA2421747A1 CA 2421747 A1 CA2421747 A1 CA 2421747A1 CA 002421747 A CA002421747 A CA 002421747A CA 2421747 A CA2421747 A CA 2421747A CA 2421747 A1 CA2421747 A1 CA 2421747A1
Authority
CA
Canada
Prior art keywords
seq
polypeptide
polynucleotide
nucleic acid
mirp1
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002421747A
Other languages
English (en)
Inventor
Steven A. N. Goldstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2421747A1 publication Critical patent/CA2421747A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

De façon générale, cette invention concerne la découverte de polymorphismes nucléotidiques spécifiques dans le gène KCNE2 et l'association de ces polymorphismes avec le syndrome du QT long induit par des antibiotiques. Sont également décrits des systèmes connexes de criblage de compostions ainsi que des essais diagnostics et pronostiques.
CA002421747A 2000-09-11 2001-09-11 Polymorphismes associes a l'arythmie cardiaque Abandoned CA2421747A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23157100P 2000-09-11 2000-09-11
US60/231,571 2000-09-11
PCT/US2001/028332 WO2002022875A2 (fr) 2000-09-11 2001-09-11 Polymorphismes associes a l'arythmie cardiaque

Publications (1)

Publication Number Publication Date
CA2421747A1 true CA2421747A1 (fr) 2002-03-21

Family

ID=22869805

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002421747A Abandoned CA2421747A1 (fr) 2000-09-11 2001-09-11 Polymorphismes associes a l'arythmie cardiaque

Country Status (3)

Country Link
AU (1) AU2001290742A1 (fr)
CA (1) CA2421747A1 (fr)
WO (1) WO2002022875A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2266042C2 (ru) * 2004-02-16 2005-12-20 Бернс Светлана Александровна Способ раннего прогнозирования возникновения в периоде постинфарктного кардиосклероза злокачественных желудочковых нарушений ритма

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2387237A1 (fr) * 1999-10-12 2001-04-19 Merck & Co., Inc. Nouvelle sous unite de canal potassique humain
US8652776B2 (en) 2007-09-10 2014-02-18 Vanda Pharmaceuticals, Inc. Prediction of QT prolongation based on SNP genotype

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998038846A2 (fr) * 1997-03-07 1998-09-11 Affymetrix, Inc. Compositions genetiques et procedes
JP4643020B2 (ja) * 1999-04-15 2011-03-02 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション MinK関連遺伝子、カリウムチャネル形成および心臓不整脈との相関

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2266042C2 (ru) * 2004-02-16 2005-12-20 Бернс Светлана Александровна Способ раннего прогнозирования возникновения в периоде постинфарктного кардиосклероза злокачественных желудочковых нарушений ритма

Also Published As

Publication number Publication date
WO2002022875A3 (fr) 2003-10-02
WO2002022875A2 (fr) 2002-03-21
AU2001290742A1 (en) 2002-03-26

Similar Documents

Publication Publication Date Title
Tiso et al. Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2)
EP1591537B1 (fr) Oligonucleotides pour la détection du gène de l'hémochromatose héréditaire
US8137915B2 (en) Genes involved in intestinal inflammatory diseases and use thereof
US7998680B2 (en) Determining genotype of a polymorphic site in the hereditary hemochromatosis gene
US20030113725A1 (en) Alpha-2 adrenergic receptor polymorphisms
JP3650397B2 (ja) フォンヒッペルーリンダウ(VHL)病遺伝子および対応するcDNAおよびVHL病遺伝子保有者の検出法
US20160258022A1 (en) Methods for Assessing Risk for Cardiac Dysrythmia in a Human Subject
US20030108924A1 (en) Method of screening for susceptibility to drug-induced cardiac arrhythmia
US20020192647A1 (en) Diagnostic method
US20080199480A1 (en) Methods for Identifying Risk of Type II Diabetes and Treatments Thereof
EP1203827A2 (fr) Polymorphismes dans le gène humain de KDR
US20040086886A1 (en) Polymorphisms associated with cardiac arrythmia
CA2471198A1 (fr) Identification de sites polymorphes dans le gene humain mglur8 et utilisations associees
CA2421747A1 (fr) Polymorphismes associes a l'arythmie cardiaque
US6562574B2 (en) Association of protein kinase C zeta polymorphisms with diabetes
WO2003022875A2 (fr) Polymorphismes de pd-1
US20030082720A1 (en) Compositions methods and kits relating to treating and diagnosing hypertension
JP2006506988A (ja) 染色体5q35に位置したヒトII型糖尿病遺伝子−SLIT−3
WO2000071751A1 (fr) Gene du diabete
WO2000006768A1 (fr) Polymorphismes genetiques du gene du recepteur neurokininique 1 de l'homme et leurs utilisations pour le diagnostic et le traitement d'affections
US6395488B1 (en) Cholecystokinin (CCK) gene as a risk factor for smoking in women
US20040249139A1 (en) Transductin-1 and transductin-2 and applications to hereditary deafness
AU767423B2 (en) Hereditary hemochromatosis gene
JP4179451B2 (ja) 多飲水症の素因の有無を予測する方法

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead