CA2420993A1 - Procedes et compositions pharmaceutiques utilisant la desmethylselegiline pour traiter des maladies ou des etats neoplasiques - Google Patents
Procedes et compositions pharmaceutiques utilisant la desmethylselegiline pour traiter des maladies ou des etats neoplasiques Download PDFInfo
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- CA2420993A1 CA2420993A1 CA002420993A CA2420993A CA2420993A1 CA 2420993 A1 CA2420993 A1 CA 2420993A1 CA 002420993 A CA002420993 A CA 002420993A CA 2420993 A CA2420993 A CA 2420993A CA 2420993 A1 CA2420993 A1 CA 2420993A1
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- selegiline
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- 229960004528 vincristine Drugs 0.000 description 1
- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
Landscapes
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La présente invention a pour objet le traitement des maladies ou états néoplasiques par l'administration de R(-) desméthylsélégiline, S(+) desméthylsélégiline, ou d'une combinaison des deux. Les maladies et états néoplasiques qui réagissent bien à R(-) desméthylsélégiline et/ou S(+) desméthylsélégiline comprennent aussi bien les néoplasmes cancéreux que les néoplasmes bénins.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22843100P | 2000-08-28 | 2000-08-28 | |
| US60/228,431 | 2000-08-28 | ||
| PCT/US2001/026658 WO2002019964A2 (fr) | 2000-08-28 | 2001-08-27 | Procedes et compositions pharmaceutiques utilisant la desmethylselegiline pour traiter des maladies ou des etats neoplasiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2420993A1 true CA2420993A1 (fr) | 2002-03-14 |
Family
ID=22857139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002420993A Abandoned CA2420993A1 (fr) | 2000-08-28 | 2001-08-27 | Procedes et compositions pharmaceutiques utilisant la desmethylselegiline pour traiter des maladies ou des etats neoplasiques |
Country Status (3)
| Country | Link |
|---|---|
| AU (2) | AU2001286798B2 (fr) |
| CA (1) | CA2420993A1 (fr) |
| WO (1) | WO2002019964A2 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE476970T1 (de) * | 2005-02-18 | 2010-08-15 | Universitaetsklinikum Freiburg | Kontrolle der androgen rezeptor-abhängigen gen expression durch hemmung der aminoxidase aktivität der lysin spezifischen demethylase (lsd1) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6033682A (en) * | 1995-01-13 | 2000-03-07 | Somerset Pharmaceuticals, Inc. | S(+) desmethylselegiline and its use in therapeutic methods and pharmaceutical compositions |
| US6319954B1 (en) * | 1995-01-13 | 2001-11-20 | Somerset Pharmaceuticals, Inc. | S-(+)-desmethylselegiline and its use in the therapeutic methods and pharmaceutical compositions |
| FI972988L (fi) * | 1995-01-13 | 1997-09-11 | Somerset Pharmaceuticals Inc | Menetelmiä ja farmaseuttisia koostumuksia, joissa käytetään desmetyyliselegiliiniä |
| US6299901B1 (en) * | 1995-01-13 | 2001-10-09 | Somerset Pharmaceuticals, Inc. | Methods and pharmaceutical compositions employing desmethylselegiline |
| WO1999018946A1 (fr) * | 1997-10-14 | 1999-04-22 | Tatton Nadine A | Techniques permettant d'accroitre la survie des cellules de schwann |
| WO1999036076A1 (fr) * | 1998-01-13 | 1999-07-22 | University Of Saskatchewan Technologies Inc. | Methode permettant d'ameliorer le traitement du cancer |
| US20020137786A1 (en) * | 1998-02-12 | 2002-09-26 | William G. Tatton | Deprenyl compounds to treat viral infections and reduce tissue damage associated therewith |
| DE69902520T2 (de) * | 1998-03-16 | 2003-04-10 | Somerset Pharmaceuticals, Inc. | Verwendung von selegilin oder desmethylselegilin zur behandlung von wunden, verbrennungen und hautschäden |
-
2001
- 2001-08-27 AU AU2001286798A patent/AU2001286798B2/en not_active Ceased
- 2001-08-27 AU AU8679801A patent/AU8679801A/xx active Pending
- 2001-08-27 WO PCT/US2001/026658 patent/WO2002019964A2/fr not_active Ceased
- 2001-08-27 CA CA002420993A patent/CA2420993A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002019964A3 (fr) | 2003-02-27 |
| AU8679801A (en) | 2002-03-22 |
| WO2002019964A2 (fr) | 2002-03-14 |
| AU2001286798B2 (en) | 2007-05-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |