CA2411401A1 - Systemes et procedes pour le controle de therapie antiretrovirale et l'orientation des decisions therapeutiques dans le traitement du vih/sida - Google Patents
Systemes et procedes pour le controle de therapie antiretrovirale et l'orientation des decisions therapeutiques dans le traitement du vih/sida Download PDFInfo
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
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- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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Abstract
L'invention concerne des essais de résistance et de susceptibilité aux médicaments antiviraux destinés à être utilisés pour l'identification de régimes posologiques efficaces dans le traitement de l'infection par le virus de l'immunodéficience humaine (VIH) et du syndrome d'immunodéficience acquis (SIDA). L'invention concerne en outre des systèmes et des procédés pour le contrôle de la progression clinique de l'infection par le VIH et de sa réponse à la thérapie antirétrovirale, en particulier la thérapie par inhibiteur de transcriptase inverse de nucléoside fondée sur des essais de susceptibilité phénotypique ou des essais génotypiques.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59189400A | 2000-06-12 | 2000-06-12 | |
| US09/591,894 | 2000-06-12 | ||
| PCT/US2001/018882 WO2001096611A1 (fr) | 2000-06-12 | 2001-06-12 | Systemes et procedes pour le controle de therapie antiretrovirale et l'orientation des decisions therapeutiques dans le traitement du vih/sida |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2411401A1 true CA2411401A1 (fr) | 2001-12-20 |
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Family Applications (1)
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|---|---|---|---|
| CA002411401A Abandoned CA2411401A1 (fr) | 2000-06-12 | 2001-06-12 | Systemes et procedes pour le controle de therapie antiretrovirale et l'orientation des decisions therapeutiques dans le traitement du vih/sida |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1292712A4 (fr) |
| JP (1) | JP2004503253A (fr) |
| CN (1) | CN1446265A (fr) |
| AU (1) | AU2001266863A1 (fr) |
| BR (1) | BR0111575A (fr) |
| CA (1) | CA2411401A1 (fr) |
| WO (1) | WO2001096611A1 (fr) |
| ZA (1) | ZA200210003B (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7037644B1 (en) | 1998-05-26 | 2006-05-02 | Virologic, Inc. | Means and methods for monitoring non-nucleoside reverse transcriptase inhibitor antiretroviral therapy and guiding therapeutic decisions in the treatment of HIV/AIDS |
| CN105647947A (zh) * | 2015-12-30 | 2016-06-08 | 南方医科大学 | 一种转移质粒及其构建方法和重组慢病毒 |
| CN105648037B (zh) * | 2015-12-30 | 2020-06-05 | 南方医科大学 | 一种重组慢病毒在hiv表型耐药检测中的应用 |
| CN120060564A (zh) * | 2016-09-07 | 2025-05-30 | 圣文森特医院悉尼有限公司 | 检测慢病毒的方法 |
| CN110832083A (zh) * | 2017-07-04 | 2020-02-21 | 卡维迪有限公司 | 用于通过测量酶活性来评估病毒对治疗的敏感性的方法及其系统 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5917033A (en) * | 1995-10-31 | 1999-06-29 | University Of Medicine & Dentistry Of New Jersey | Structure based design of inhibitors of HIV-1 reverse transcriptase |
| WO1997027332A1 (fr) * | 1996-01-26 | 1997-07-31 | Innogenetics N.V. | Procede de detection de mutations induites par des medicaments dans le gene de la transcriptase reverse |
| KR100495690B1 (ko) * | 1996-01-26 | 2005-11-08 | 비르코 비브이비에이 | 인체 hiv 계통의 표현형적 약제 감수성에 기초한 하나 이상의 최적한 hiv 저해제를 선발하는 방법 |
| CN1204266C (zh) * | 1998-05-26 | 2005-06-01 | 病毒科学公司 | 监控非核苷类逆转录酶抑制剂抗逆转录病毒治疗的途径与方法 |
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2001
- 2001-06-12 AU AU2001266863A patent/AU2001266863A1/en not_active Abandoned
- 2001-06-12 BR BR0111575-8A patent/BR0111575A/pt not_active IP Right Cessation
- 2001-06-12 JP JP2002510724A patent/JP2004503253A/ja active Pending
- 2001-06-12 CN CN01814056A patent/CN1446265A/zh active Pending
- 2001-06-12 EP EP01944452A patent/EP1292712A4/fr not_active Withdrawn
- 2001-06-12 WO PCT/US2001/018882 patent/WO2001096611A1/fr not_active Ceased
- 2001-06-12 CA CA002411401A patent/CA2411401A1/fr not_active Abandoned
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2002
- 2002-12-10 ZA ZA200210003A patent/ZA200210003B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1292712A1 (fr) | 2003-03-19 |
| WO2001096611A1 (fr) | 2001-12-20 |
| EP1292712A4 (fr) | 2005-04-20 |
| BR0111575A (pt) | 2003-06-24 |
| CN1446265A (zh) | 2003-10-01 |
| AU2001266863A1 (en) | 2001-12-24 |
| JP2004503253A (ja) | 2004-02-05 |
| ZA200210003B (en) | 2004-12-22 |
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