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CA2403912A1 - Polynucleotides agissant sur des genes de desaturase-delta-6 et techniques d'identification de composes permettant de moduler la desaturase-delta-6 - Google Patents

Polynucleotides agissant sur des genes de desaturase-delta-6 et techniques d'identification de composes permettant de moduler la desaturase-delta-6 Download PDF

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Publication number
CA2403912A1
CA2403912A1 CA002403912A CA2403912A CA2403912A1 CA 2403912 A1 CA2403912 A1 CA 2403912A1 CA 002403912 A CA002403912 A CA 002403912A CA 2403912 A CA2403912 A CA 2403912A CA 2403912 A1 CA2403912 A1 CA 2403912A1
Authority
CA
Canada
Prior art keywords
sequence
desaturase
group
polynucleotide
homologous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002403912A
Other languages
English (en)
Inventor
Michael David Winther
Heidi Lynn Smith
Stephen John Allen
Andre Ponton
Roberto Justo De Antueno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xenon Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002301158A external-priority patent/CA2301158A1/fr
Application filed by Individual filed Critical Individual
Priority to CA002403912A priority Critical patent/CA2403912A1/fr
Publication of CA2403912A1 publication Critical patent/CA2403912A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Cette invention a trait à des polynucléotides agissant sur des gènes de désaturase ainsi qu'à des épreuves de criblage de médicaments permettant d'identifier des composés actifs du point de vue pharmaceutique à utiliser pour traiter des états pathologiques se traduisant par un métabolisme anormal des lipides, notamment la neuropathie diabétique, avec utilisation de désaturase d'acides gras et les gènes qui la codent comme cibles pour intervention. L'épreuve de criblage de médicament permet d'identifier des nucléotides, des protéines, des composés et/au d'autres agents pharmacologiques, modulant efficacement l'activité des désaturases ou régulant le taux d'expression des gènes de désaturase.
CA002403912A 2000-03-24 2001-03-26 Polynucleotides agissant sur des genes de desaturase-delta-6 et techniques d'identification de composes permettant de moduler la desaturase-delta-6 Abandoned CA2403912A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002403912A CA2403912A1 (fr) 2000-03-24 2001-03-26 Polynucleotides agissant sur des genes de desaturase-delta-6 et techniques d'identification de composes permettant de moduler la desaturase-delta-6

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CA2,301,158 2000-03-24
CA002301158A CA2301158A1 (fr) 2000-03-24 2000-03-24 Methodes de depistage de composes utilises pour moduler le metabolisme lipidique dans les maladies
PCT/CA2001/000398 WO2001070993A2 (fr) 2000-03-24 2001-03-26 Polynucleotides agissant sur des genes de desaturase-delta-6 et techniques d'identification de composes permettant de moduler la desaturase-delta-6
CA002403912A CA2403912A1 (fr) 2000-03-24 2001-03-26 Polynucleotides agissant sur des genes de desaturase-delta-6 et techniques d'identification de composes permettant de moduler la desaturase-delta-6

Publications (1)

Publication Number Publication Date
CA2403912A1 true CA2403912A1 (fr) 2001-09-27

Family

ID=25681632

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002403912A Abandoned CA2403912A1 (fr) 2000-03-24 2001-03-26 Polynucleotides agissant sur des genes de desaturase-delta-6 et techniques d'identification de composes permettant de moduler la desaturase-delta-6

Country Status (1)

Country Link
CA (1) CA2403912A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111321155A (zh) * 2020-03-24 2020-06-23 吉林省农业科学院 在原核细胞中增殖功能性马铃薯y病毒的方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111321155A (zh) * 2020-03-24 2020-06-23 吉林省农业科学院 在原核细胞中增殖功能性马铃薯y病毒的方法
CN111321155B (zh) * 2020-03-24 2022-08-02 吉林省农业科学院 在原核细胞中增殖功能性马铃薯y病毒的方法

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued