CA2494473A1 - Compositions de proteines stabilisees pour administration topique et methodes pour les produire - Google Patents

Compositions de proteines stabilisees pour administration topique et methodes pour les produire Download PDF

Info

Publication number: CA2494473A1
Authority: CA; Canada
Prior art keywords: methods; topical administration; making same; protein compositions; stabilized protein
Prior art date: 2005-02-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA 2494473

Other languages

English (en)

Other versions

CA2494473C (fr

Inventor

Pankaj Modi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

DPM Therapeutics Corp

Original Assignee

DPM Therapeutics Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-02-14

Filing date

2005-02-14

Publication date

2005-04-25

2005-02-14 Application filed by DPM Therapeutics Corp filed Critical DPM Therapeutics Corp

2005-02-14 Priority to CA002494473A priority Critical patent/CA2494473C/fr

2005-04-25 Publication of CA2494473A1 publication Critical patent/CA2494473A1/fr

2006-02-08 Priority to PT67051235T priority patent/PT1853303E/pt

2006-02-08 Priority to EP06705123.5A priority patent/EP1853303B1/fr

2006-02-08 Priority to ES06705123.5T priority patent/ES2562494T3/es

2006-02-08 Priority to PCT/CA2006/000167 priority patent/WO2006084353A1/fr

2006-02-08 Priority to PL06705123T priority patent/PL1853303T3/pl

2006-02-08 Priority to DK06705123.5T priority patent/DK1853303T3/en

2007-06-26 Application granted granted Critical

2007-06-26 Publication of CA2494473C publication Critical patent/CA2494473C/fr

2025-02-14 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

239000000203 mixture Substances 0.000 title abstract 5
238000000034 method Methods 0.000 title abstract 2
102000004169 proteins and genes Human genes 0.000 title 1
108090000623 proteins and genes Proteins 0.000 title 1
238000011200 topical administration Methods 0.000 title 1
239000013543 active substance Substances 0.000 abstract 2
230000000087 stabilizing effect Effects 0.000 abstract 2
JSPNNZKWADNWHI-PNANGNLXSA-N (2r)-2-hydroxy-n-[(2s,3r,4e,8e)-3-hydroxy-9-methyl-1-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadeca-4,8-dien-2-yl]heptadecanamide Chemical compound CCCCCCCCCCCCCCC[C@@H](O)C(=O)N[C@H]([C@H](O)\C=C\CC\C=C(/C)CCCCCCCCC)CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O JSPNNZKWADNWHI-PNANGNLXSA-N 0.000 abstract 1
102000008186 Collagen Human genes 0.000 abstract 1
108010035532 Collagen Proteins 0.000 abstract 1
102000016942 Elastin Human genes 0.000 abstract 1
108010014258 Elastin Proteins 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
229930183167 cerebroside Natural products 0.000 abstract 1
RIZIAUKTHDLMQX-UHFFFAOYSA-N cerebroside D Natural products CCCCCCCCCCCCCCCCC(O)C(=O)NC(C(O)C=CCCC=C(C)CCCCCCCCC)COC1OC(CO)C(O)C(O)C1O RIZIAUKTHDLMQX-UHFFFAOYSA-N 0.000 abstract 1
229920001436 collagen Polymers 0.000 abstract 1
239000002537 cosmetic Substances 0.000 abstract 1
229920002549 elastin Polymers 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Birds (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Dermatology (AREA)
Gerontology & Geriatric Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Cosmetics (AREA)
Medicinal Preparation (AREA)

CA002494473A 2005-02-14 2005-02-14 Compositions de proteines stabilisees pour administration topique et methodes pour les produire Expired - Fee Related CA2494473C (fr)

Priority Applications (7)

Application Number	Priority Date	Filing Date	Title
CA002494473A CA2494473C (fr)	2005-02-14	2005-02-14	Compositions de proteines stabilisees pour administration topique et methodes pour les produire
PT67051235T PT1853303E (pt)	2005-02-14	2006-02-08	Composições estabilizadas para administração tópica, e métodos para a sua preparação
EP06705123.5A EP1853303B1 (fr)	2005-02-14	2006-02-08	Préparations stabilisées pour administration locale et méthodes d'elaboration desdites préparations
ES06705123.5T ES2562494T3 (es)	2005-02-14	2006-02-08	Composiciones estabilizadas para administración tópica y métodos para preparar las mismas
PCT/CA2006/000167 WO2006084353A1 (fr)	2005-02-14	2006-02-08	Préparations stabilisées pour administration locale et méthodes d'élaboration desdites préparations
PL06705123T PL1853303T3 (pl)	2005-02-14	2006-02-08	Stabilizowane kompozycje do podawania miejscowego i sposoby ich otrzymywania
DK06705123.5T DK1853303T3 (en)	2005-02-14	2006-02-08	STABILIZED COMPOSITIONS FOR TOPIC ADMINISTRATION AND PROCEDURES FOR PREPARING IT

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CA002494473A CA2494473C (fr)	2005-02-14	2005-02-14	Compositions de proteines stabilisees pour administration topique et methodes pour les produire

Publications (2)

Publication Number	Publication Date
CA2494473A1 true CA2494473A1 (fr)	2005-04-25
CA2494473C CA2494473C (fr)	2007-06-26

Family

ID=34468770

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002494473A Expired - Fee Related CA2494473C (fr)	2005-02-14	2005-02-14	Compositions de proteines stabilisees pour administration topique et methodes pour les produire

Country Status (1)

Country	Link
CA (1)	CA2494473C (fr)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2007089454A3 (fr) *	2006-01-27	2007-09-20	Allergan Inc	Procédés pour améliorer des traitements pour la peau
JP2009518307A (ja) *	2005-12-01	2009-05-07	ユニバーシティオブマサチューセッツロウエル	ボツリヌス菌ナノエマルジョン
US8530410B2 (en)	2004-04-02	2013-09-10	Allergan, Inc.	Method for treating a keloid with a botulinum toxin
US10016364B2 (en)	2005-07-18	2018-07-10	University Of Massachusetts Lowell	Compositions and methods for making and using nanoemulsions
US10076557B2 (en)	2003-12-09	2018-09-18	Allergan, Inc.	Botulinum toxin therapy for skin disorders
US10285941B2 (en)	2006-12-01	2019-05-14	Anterios, Inc.	Amphiphilic entity nanoparticles
US10532019B2 (en)	2005-12-01	2020-01-14	University Of Massachusetts Lowell	Botulinum nanoemulsions
US10905637B2 (en)	2006-12-01	2021-02-02	Anterios, Inc.	Peptide nanoparticles and uses therefor
CN115212131A (zh) *	2022-06-16	2022-10-21	广东格烯生物科技股份有限公司	一种含有重组弹性蛋白的抗皱紧致精华及其制备方法
US12036263B2 (en)	2019-07-03	2024-07-16	Illustris Pharmaceuticals, Inc.	Topical compositions
US12083204B2 (en)	2022-06-02	2024-09-10	L'oreal	Topical composition for homeostatic delivery of nitric oxide and uses thereof

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2008151022A2 (fr)	2007-05-31	2008-12-11	Anterios, Inc.	Nanoparticules d'acide nucléique et leurs utilisations
KR102487144B1 (ko)	2016-11-21	2023-01-12	에이리온 테라퓨틱스, 인코포레이티드	큰 물질의 경피 전달

2005
- 2005-02-14 CA CA002494473A patent/CA2494473C/fr not_active Expired - Fee Related

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US10076557B2 (en)	2003-12-09	2018-09-18	Allergan, Inc.	Botulinum toxin therapy for skin disorders
US8530410B2 (en)	2004-04-02	2013-09-10	Allergan, Inc.	Method for treating a keloid with a botulinum toxin
US10016364B2 (en)	2005-07-18	2018-07-10	University Of Massachusetts Lowell	Compositions and methods for making and using nanoemulsions
US10576034B2 (en)	2005-12-01	2020-03-03	University Of Massachusetts Lowell	Botulinum nanoemulsions
JP2009518307A (ja) *	2005-12-01	2009-05-07	ユニバーシティオブマサチューセッツロウエル	ボツリヌス菌ナノエマルジョン
JP2013189444A (ja) *	2005-12-01	2013-09-26	Univ Of Massachusetts Lowell	ボツリヌス菌ナノエマルジョン
JP2016006065A (ja) *	2005-12-01	2016-01-14	ユニバーシティオブマサチューセッツロウエル	ボツリヌス菌ナノエマルジョン
JP2018024676A (ja) *	2005-12-01	2018-02-15	ユニバーシティオブマサチューセッツロウエル	ボツリヌス菌ナノエマルジョン
US10532019B2 (en)	2005-12-01	2020-01-14	University Of Massachusetts Lowell	Botulinum nanoemulsions
JP2020023500A (ja) *	2005-12-01	2020-02-13	ユニバーシティオブマサチューセッツロウエル	ボツリヌス菌ナノエマルジョン
WO2007089454A3 (fr) *	2006-01-27	2007-09-20	Allergan Inc	Procédés pour améliorer des traitements pour la peau
US10285941B2 (en)	2006-12-01	2019-05-14	Anterios, Inc.	Amphiphilic entity nanoparticles
US10758485B2 (en)	2006-12-01	2020-09-01	Anterios, Inc.	Amphiphilic entity nanoparticles
US10905637B2 (en)	2006-12-01	2021-02-02	Anterios, Inc.	Peptide nanoparticles and uses therefor
US12036263B2 (en)	2019-07-03	2024-07-16	Illustris Pharmaceuticals, Inc.	Topical compositions
US12083204B2 (en)	2022-06-02	2024-09-10	L'oreal	Topical composition for homeostatic delivery of nitric oxide and uses thereof
CN115212131A (zh) *	2022-06-16	2022-10-21	广东格烯生物科技股份有限公司	一种含有重组弹性蛋白的抗皱紧致精华及其制备方法
CN115212131B (zh) *	2022-06-16	2023-09-08	广东格烯生物科技股份有限公司	一种含有重组弹性蛋白的抗皱紧致精华及其制备方法

Also Published As

Publication number	Publication date
CA2494473C (fr)	2007-06-26

Publication	Publication Date	Title
WO2004043363A3 (fr)	2004-08-12	Preparations liposomales d'agents pharmaceutiques stabilisees par des proteines
MY144992A (en)	2011-12-15	Substituted 1,2,3,4-tetrahydroisoquinoline derivatives.
WO2006037116A3 (fr)	2006-06-01	Vehicule d'administration semi-solide et compositions pharmaceutiques
MX9505182A (es)	1997-02-28	Composicion terapeutica para aplicacion topica, que contiene un antagonista de la substancia p.
ATE258426T1 (de)	2004-02-15	Zusammensetzungen und verfahren zur topischen anwendungen von wirkstoffen
CA2492976A1 (fr)	2004-03-18	Solution destinee a une application ungueale et peri-ungueale
BRPI0508579A (pt)	2007-08-14	composto, composição farmacêutica, e, uso de um composto
MY143795A (en)	2011-07-15	Tetrahydropyridoindole derivatives
WO2005018574A3 (fr)	2006-01-12	Combinaisons et traitements immunostimulatoires
BG66093B1 (bg)	2011-04-29	Състави с контролирано освобождаване, съдържащи нимесулид
CA2494473A1 (fr)	2005-04-25	Compositions de proteines stabilisees pour administration topique et methodes pour les produire
MXPA05012753A (es)	2006-02-13	Composiciones cosmeticas estables que comprenden un agente autobronceador.
WO2004071538A3 (fr)	2005-06-23	Procede d'administration d'agents cosmetiques par application topique
AU2108500A (en)	2000-08-18	Galenic formulation containing biotin
WO2006060515A3 (fr)	2006-08-17	Systeme permettant d'ameliorer l'absorption percutanee d'agents benefiques pour la peau
WO2002030467A3 (fr)	2002-10-24	Composition destinee a soigner des plaies, renfermant un compose actif du point de vue therapeutique, du miel notamment
DK1280558T3 (da)	2005-12-27	Halvfast indgivelsesvehikel og farmaceutiske sammensætninger
CA2571796A1 (fr)	2006-01-19	Compositions cosmetiques et procede a base d'un agent bronzant et d'acide ursolique encapsule dans un liposome
WO2006089114A3 (fr)	2007-01-11	Procedes et compositions pour le traitement d'un sujet souffrant d'un etat a mediation assuree par la toxine de l'anthrax
PT1414467E (pt)	2006-09-29	Tratamento topico da mastalgia
TNSN07203A1 (en)	2008-11-21	Pharmaceutical compositions for the treatment of cellulite
JP2003523397A5 (fr)	2008-03-13
SI1893237T1 (sl)	2010-03-31	Farmacevtska zmes ki vsebuje organopolisiloksan elastomer in učinkovino v obliki raztopine
JO2492B1 (en)	2009-10-05	A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients
PL1868631T3 (pl)	2010-10-29	Zastosowanie związków indukujących syntezę białek SIRT przy lub dla otrzymywania kompozycji kosmetycznej lub farmaceutycznej

Legal Events

Date	Code	Title	Description
2005-02-18	EEER	Examination request
2022-09-27	MKLA	Lapsed	Effective date: 20210215