CA2477019A1 - Use of total coumarins of cnidium fruit in preparing medicaments for treating psoriasis - Google Patents
Use of total coumarins of cnidium fruit in preparing medicaments for treating psoriasis Download PDFInfo
- Publication number
- CA2477019A1 CA2477019A1 CA002477019A CA2477019A CA2477019A1 CA 2477019 A1 CA2477019 A1 CA 2477019A1 CA 002477019 A CA002477019 A CA 002477019A CA 2477019 A CA2477019 A CA 2477019A CA 2477019 A1 CA2477019 A1 CA 2477019A1
- Authority
- CA
- Canada
- Prior art keywords
- total coumarins
- treating psoriasis
- cnidium fruit
- preparing medicaments
- psoriasis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 201000004681 Psoriasis Diseases 0.000 title abstract 3
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N benzo-alpha-pyrone Natural products C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 title abstract 3
- 235000001671 coumarin Nutrition 0.000 title abstract 3
- 150000004775 coumarins Chemical class 0.000 title abstract 3
- 241000212948 Cnidium Species 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 235000013399 edible fruits Nutrition 0.000 title abstract 2
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pyrane Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present invention relates to a use of total coumarins of cnidium fruit in preparation of a medicament for treating psoriasis. The total coumarins of the invention can improve the clinical symptom of psoriasis, have higher curative effect and are safe to use. It can be administrated both externally and orally.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021149038A CN1197867C (en) | 2002-02-27 | 2002-02-27 | Application of total coumarins from Cnidium Fructus Cnidii in the preparation of medicines for treating psoriasis |
| CN02114903.8 | 2002-02-27 | ||
| PCT/CN2003/000150 WO2003072120A1 (en) | 2002-02-27 | 2003-02-26 | The use of the total coumarins of cnidium monnieri in preparation of the medicament for treating psoriasis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2477019A1 true CA2477019A1 (en) | 2003-09-04 |
| CA2477019C CA2477019C (en) | 2009-10-27 |
Family
ID=4743351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002477019A Expired - Lifetime CA2477019C (en) | 2002-02-27 | 2003-02-26 | Use of total coumarins of cnidium fruit in preparing medicaments for treating psoriasis |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US8124133B2 (en) |
| EP (1) | EP1486213B1 (en) |
| JP (1) | JP4613012B2 (en) |
| KR (2) | KR101016680B1 (en) |
| CN (2) | CN1327837C (en) |
| AT (1) | ATE541579T1 (en) |
| AU (1) | AU2003221280B2 (en) |
| CA (1) | CA2477019C (en) |
| DK (1) | DK1486213T3 (en) |
| RU (1) | RU2311188C2 (en) |
| WO (1) | WO2003072120A1 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6596125B2 (en) | 2001-09-21 | 2003-07-22 | Philip Morris Incorporated | Method and apparatus for applying a material to a web |
| CN1327837C (en) * | 2002-02-27 | 2007-07-25 | 杨利平 | Medicine for treating allergic skin disease and its preparation process |
| US20070065377A1 (en) * | 2003-10-17 | 2007-03-22 | Mu-Hyun Jin | Composition for promoting synthesis of collagen, and composition for external preparation for skin comprising the same |
| CN100404524C (en) * | 2005-07-22 | 2008-07-23 | 中国医学科学院放射医学研究所 | High-purity osthole, preparation method thereof, and pharmaceutical composition containing the compound as an active ingredient |
| JP2009137889A (en) * | 2007-12-06 | 2009-06-25 | Lion Corp | Hair restorer, hair restorer composition, and hair restorer method |
| KR101698830B1 (en) * | 2015-04-08 | 2017-01-23 | 주식회사 오비엠랩 | Composition for inhibiting or improving seborrhea or seborrheic dermatitis |
| KR20190046241A (en) | 2017-10-25 | 2019-05-07 | (주)예스킨 | Composition for treating psoriasis |
| CN108030903A (en) * | 2017-12-14 | 2018-05-15 | 珠海横琴新区德群中医药科学研究院有限公司 | One kind is used to treat psoriasic Chinese medicine |
| RU2743848C1 (en) * | 2020-06-25 | 2021-02-26 | Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) | Method for correcting hypercoagulable state when antitumor drug cisplatin is administered by injection |
| CN111728968A (en) * | 2020-07-08 | 2020-10-02 | 桂林医学院 | Application of daphnetin in preparation of medicine for treating psoriasis |
| CN112426413A (en) * | 2020-11-13 | 2021-03-02 | 川北医学院附属医院 | Preparation method and application of xanthotoxol water-soluble nano novel dosage form |
| CN115969891B (en) * | 2022-10-13 | 2025-01-21 | 杨利平 | A total extract of Cnidium monnieri and its application and map construction method |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5953477A (en) | 1982-09-20 | 1984-03-28 | Res Inst For Prod Dev | Coumarin derivative |
| JPS5953476A (en) | 1982-09-20 | 1984-03-28 | Res Inst For Prod Dev | coumarin derivatives |
| JPH01235036A (en) * | 1988-03-15 | 1989-09-20 | Sony Corp | Optical pickup device |
| JPH0459733A (en) * | 1990-06-29 | 1992-02-26 | Ota Isan:Kk | Functional disorder improver caused by stress comprising extracted and purified substance of cnidii monnieri fructus as active ingredient |
| RU2074730C1 (en) * | 1993-05-24 | 1997-03-10 | Николай Яковлевич Костеша | Ointment for skin diseases treatment: eczema, psoriasis, neurodermatitis |
| KR0148511B1 (en) * | 1993-09-14 | 1998-11-02 | 최형기 | Pharmaceutical composition for prophylaxis and treatment of sexual nervous hyper sensitivity |
| CN1102993A (en) * | 1993-12-21 | 1995-05-31 | 吴文才 | Method for making Chinese medicine herbs preparation by polyenzyme system |
| JP3577110B2 (en) * | 1994-08-29 | 2004-10-13 | 株式会社ヤクルト本社 | ACAT inhibitor |
| US5961997A (en) * | 1997-03-25 | 1999-10-05 | Swinehart; James M. | Antipruritic composition |
| RU2139721C1 (en) * | 1998-02-26 | 1999-10-20 | Калиняк Игорь Петрович | Method of balsamic agent "gliprosan" preparing |
| JP2002255812A (en) * | 2001-03-02 | 2002-09-11 | Dai Ichi Seiyaku Co Ltd | Antipruritic agent |
| CN1327837C (en) * | 2002-02-27 | 2007-07-25 | 杨利平 | Medicine for treating allergic skin disease and its preparation process |
-
2002
- 2002-02-27 CN CNB2004100792505A patent/CN1327837C/en not_active Expired - Lifetime
- 2002-02-27 CN CNB021149038A patent/CN1197867C/en not_active Expired - Lifetime
-
2003
- 2003-02-26 AT AT03709569T patent/ATE541579T1/en active
- 2003-02-26 KR KR1020047013365A patent/KR101016680B1/en not_active Expired - Fee Related
- 2003-02-26 RU RU2004128461/15A patent/RU2311188C2/en active
- 2003-02-26 JP JP2003570865A patent/JP4613012B2/en not_active Expired - Fee Related
- 2003-02-26 KR KR1020107018912A patent/KR101207479B1/en not_active Expired - Fee Related
- 2003-02-26 WO PCT/CN2003/000150 patent/WO2003072120A1/en not_active Ceased
- 2003-02-26 US US10/505,015 patent/US8124133B2/en not_active Expired - Lifetime
- 2003-02-26 DK DK03709569.2T patent/DK1486213T3/en active
- 2003-02-26 AU AU2003221280A patent/AU2003221280B2/en not_active Ceased
- 2003-02-26 EP EP03709569A patent/EP1486213B1/en not_active Expired - Lifetime
- 2003-02-26 CA CA002477019A patent/CA2477019C/en not_active Expired - Lifetime
-
2012
- 2012-01-21 US US13/355,532 patent/US8518460B2/en not_active Expired - Fee Related
-
2013
- 2013-08-01 US US13/956,378 patent/US10383843B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2004128461A (en) | 2005-03-27 |
| KR20100099352A (en) | 2010-09-10 |
| EP1486213A1 (en) | 2004-12-15 |
| AU2003221280B2 (en) | 2007-06-28 |
| JP4613012B2 (en) | 2011-01-12 |
| US20120115940A1 (en) | 2012-05-10 |
| CN1197867C (en) | 2005-04-20 |
| US8124133B2 (en) | 2012-02-28 |
| EP1486213A4 (en) | 2006-04-26 |
| JP2005530697A (en) | 2005-10-13 |
| AU2003221280A1 (en) | 2003-09-09 |
| US10383843B2 (en) | 2019-08-20 |
| KR101016680B1 (en) | 2011-02-25 |
| CN1327837C (en) | 2007-07-25 |
| ATE541579T1 (en) | 2012-02-15 |
| US20050123636A1 (en) | 2005-06-09 |
| WO2003072120A1 (en) | 2003-09-04 |
| US20150038568A1 (en) | 2015-02-05 |
| KR20040083461A (en) | 2004-10-01 |
| DK1486213T3 (en) | 2012-05-14 |
| CN1374309A (en) | 2002-10-16 |
| CA2477019C (en) | 2009-10-27 |
| CN1701791A (en) | 2005-11-30 |
| KR101207479B1 (en) | 2012-12-03 |
| EP1486213B1 (en) | 2012-01-18 |
| US8518460B2 (en) | 2013-08-27 |
| RU2311188C2 (en) | 2007-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20230227 |