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CA2477019A1 - Use of total coumarins of cnidium fruit in preparing medicaments for treating psoriasis - Google Patents

Use of total coumarins of cnidium fruit in preparing medicaments for treating psoriasis Download PDF

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Publication number
CA2477019A1
CA2477019A1 CA002477019A CA2477019A CA2477019A1 CA 2477019 A1 CA2477019 A1 CA 2477019A1 CA 002477019 A CA002477019 A CA 002477019A CA 2477019 A CA2477019 A CA 2477019A CA 2477019 A1 CA2477019 A1 CA 2477019A1
Authority
CA
Canada
Prior art keywords
total coumarins
treating psoriasis
cnidium fruit
preparing medicaments
psoriasis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002477019A
Other languages
French (fr)
Other versions
CA2477019C (en
Inventor
Liping Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2477019A1 publication Critical patent/CA2477019A1/en
Application granted granted Critical
Publication of CA2477019C publication Critical patent/CA2477019C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37Coumarins, e.g. psoralen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234Cnidium (snowparsley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pyrane Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to a use of total coumarins of cnidium fruit in preparation of a medicament for treating psoriasis. The total coumarins of the invention can improve the clinical symptom of psoriasis, have higher curative effect and are safe to use. It can be administrated both externally and orally.
CA002477019A 2002-02-27 2003-02-26 Use of total coumarins of cnidium fruit in preparing medicaments for treating psoriasis Expired - Lifetime CA2477019C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNB021149038A CN1197867C (en) 2002-02-27 2002-02-27 Application of total coumarins from Cnidium Fructus Cnidii in the preparation of medicines for treating psoriasis
CN02114903.8 2002-02-27
PCT/CN2003/000150 WO2003072120A1 (en) 2002-02-27 2003-02-26 The use of the total coumarins of cnidium monnieri in preparation of the medicament for treating psoriasis

Publications (2)

Publication Number Publication Date
CA2477019A1 true CA2477019A1 (en) 2003-09-04
CA2477019C CA2477019C (en) 2009-10-27

Family

ID=4743351

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002477019A Expired - Lifetime CA2477019C (en) 2002-02-27 2003-02-26 Use of total coumarins of cnidium fruit in preparing medicaments for treating psoriasis

Country Status (11)

Country Link
US (3) US8124133B2 (en)
EP (1) EP1486213B1 (en)
JP (1) JP4613012B2 (en)
KR (2) KR101016680B1 (en)
CN (2) CN1327837C (en)
AT (1) ATE541579T1 (en)
AU (1) AU2003221280B2 (en)
CA (1) CA2477019C (en)
DK (1) DK1486213T3 (en)
RU (1) RU2311188C2 (en)
WO (1) WO2003072120A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596125B2 (en) 2001-09-21 2003-07-22 Philip Morris Incorporated Method and apparatus for applying a material to a web
CN1327837C (en) * 2002-02-27 2007-07-25 杨利平 Medicine for treating allergic skin disease and its preparation process
US20070065377A1 (en) * 2003-10-17 2007-03-22 Mu-Hyun Jin Composition for promoting synthesis of collagen, and composition for external preparation for skin comprising the same
CN100404524C (en) * 2005-07-22 2008-07-23 中国医学科学院放射医学研究所 High-purity osthole, preparation method thereof, and pharmaceutical composition containing the compound as an active ingredient
JP2009137889A (en) * 2007-12-06 2009-06-25 Lion Corp Hair restorer, hair restorer composition, and hair restorer method
KR101698830B1 (en) * 2015-04-08 2017-01-23 주식회사 오비엠랩 Composition for inhibiting or improving seborrhea or seborrheic dermatitis
KR20190046241A (en) 2017-10-25 2019-05-07 (주)예스킨 Composition for treating psoriasis
CN108030903A (en) * 2017-12-14 2018-05-15 珠海横琴新区德群中医药科学研究院有限公司 One kind is used to treat psoriasic Chinese medicine
RU2743848C1 (en) * 2020-06-25 2021-02-26 Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) Method for correcting hypercoagulable state when antitumor drug cisplatin is administered by injection
CN111728968A (en) * 2020-07-08 2020-10-02 桂林医学院 Application of daphnetin in preparation of medicine for treating psoriasis
CN112426413A (en) * 2020-11-13 2021-03-02 川北医学院附属医院 Preparation method and application of xanthotoxol water-soluble nano novel dosage form
CN115969891B (en) * 2022-10-13 2025-01-21 杨利平 A total extract of Cnidium monnieri and its application and map construction method

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5953477A (en) 1982-09-20 1984-03-28 Res Inst For Prod Dev Coumarin derivative
JPS5953476A (en) 1982-09-20 1984-03-28 Res Inst For Prod Dev coumarin derivatives
JPH01235036A (en) * 1988-03-15 1989-09-20 Sony Corp Optical pickup device
JPH0459733A (en) * 1990-06-29 1992-02-26 Ota Isan:Kk Functional disorder improver caused by stress comprising extracted and purified substance of cnidii monnieri fructus as active ingredient
RU2074730C1 (en) * 1993-05-24 1997-03-10 Николай Яковлевич Костеша Ointment for skin diseases treatment: eczema, psoriasis, neurodermatitis
KR0148511B1 (en) * 1993-09-14 1998-11-02 최형기 Pharmaceutical composition for prophylaxis and treatment of sexual nervous hyper sensitivity
CN1102993A (en) * 1993-12-21 1995-05-31 吴文才 Method for making Chinese medicine herbs preparation by polyenzyme system
JP3577110B2 (en) * 1994-08-29 2004-10-13 株式会社ヤクルト本社 ACAT inhibitor
US5961997A (en) * 1997-03-25 1999-10-05 Swinehart; James M. Antipruritic composition
RU2139721C1 (en) * 1998-02-26 1999-10-20 Калиняк Игорь Петрович Method of balsamic agent "gliprosan" preparing
JP2002255812A (en) * 2001-03-02 2002-09-11 Dai Ichi Seiyaku Co Ltd Antipruritic agent
CN1327837C (en) * 2002-02-27 2007-07-25 杨利平 Medicine for treating allergic skin disease and its preparation process

Also Published As

Publication number Publication date
RU2004128461A (en) 2005-03-27
KR20100099352A (en) 2010-09-10
EP1486213A1 (en) 2004-12-15
AU2003221280B2 (en) 2007-06-28
JP4613012B2 (en) 2011-01-12
US20120115940A1 (en) 2012-05-10
CN1197867C (en) 2005-04-20
US8124133B2 (en) 2012-02-28
EP1486213A4 (en) 2006-04-26
JP2005530697A (en) 2005-10-13
AU2003221280A1 (en) 2003-09-09
US10383843B2 (en) 2019-08-20
KR101016680B1 (en) 2011-02-25
CN1327837C (en) 2007-07-25
ATE541579T1 (en) 2012-02-15
US20050123636A1 (en) 2005-06-09
WO2003072120A1 (en) 2003-09-04
US20150038568A1 (en) 2015-02-05
KR20040083461A (en) 2004-10-01
DK1486213T3 (en) 2012-05-14
CN1374309A (en) 2002-10-16
CA2477019C (en) 2009-10-27
CN1701791A (en) 2005-11-30
KR101207479B1 (en) 2012-12-03
EP1486213B1 (en) 2012-01-18
US8518460B2 (en) 2013-08-27
RU2311188C2 (en) 2007-11-27

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Effective date: 20230227