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CA2471572A1 - Compositions a base de taxane et procedes d'utilisation - Google Patents

Compositions a base de taxane et procedes d'utilisation Download PDF

Info

Publication number
CA2471572A1
CA2471572A1 CA002471572A CA2471572A CA2471572A1 CA 2471572 A1 CA2471572 A1 CA 2471572A1 CA 002471572 A CA002471572 A CA 002471572A CA 2471572 A CA2471572 A CA 2471572A CA 2471572 A1 CA2471572 A1 CA 2471572A1
Authority
CA
Canada
Prior art keywords
composition
taxane
weight
amount
paclitaxel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002471572A
Other languages
English (en)
Inventor
Gregory A. Smith
Kai Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ivax Research Holdings Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2471572A1 publication Critical patent/CA2471572A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Compounds (AREA)

Abstract

L'invention concerne des compositions à base de taxane et des procédés d'utilisation de ces dernières pour atteindre des niveaux sanguins cibles de taxane chez un mammifère, par exemple, pour traiter les maladies malignes et non malignes répondant à la taxane. L'invention traite de compositions qui présentent une stabilité à long terme et une appétibilité globale. L'invention a aussi pour objet des procédés d'utilisation des compositions comme outils analytiques pour réaliser des études pharmacocinétiques.
CA002471572A 2001-12-28 2002-12-27 Compositions a base de taxane et procedes d'utilisation Abandoned CA2471572A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34492101P 2001-12-28 2001-12-28
US60/344,921 2001-12-28
PCT/US2002/041632 WO2003057208A1 (fr) 2001-12-28 2002-12-27 Compositions a base de taxane et procedes d'utilisation

Publications (1)

Publication Number Publication Date
CA2471572A1 true CA2471572A1 (fr) 2003-07-17

Family

ID=23352677

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002471572A Abandoned CA2471572A1 (fr) 2001-12-28 2002-12-27 Compositions a base de taxane et procedes d'utilisation

Country Status (7)

Country Link
EP (1) EP1461029A1 (fr)
JP (1) JP2005525310A (fr)
KR (1) KR20040081441A (fr)
CN (1) CN1615130A (fr)
AU (1) AU2002360816A1 (fr)
CA (1) CA2471572A1 (fr)
WO (1) WO2003057208A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1510206A1 (fr) * 2003-08-29 2005-03-02 Novagali Pharma SA Formulation huileuse auto-émulsifiable pour l'administration de principes actifs peu solubles dans l'eau
CA2552925A1 (fr) * 2004-01-30 2005-08-18 Pfizer Italia S.R.L. Formulations pharmaceutiques a matrice semi-solide
US7989490B2 (en) 2004-06-02 2011-08-02 Cordis Corporation Injectable formulations of taxanes for cad treatment
US8003122B2 (en) 2004-03-31 2011-08-23 Cordis Corporation Device for local and/or regional delivery employing liquid formulations of therapeutic agents
CN100508970C (zh) * 2006-10-10 2009-07-08 上海格鲁奥丽生物医药技术有限公司 黄芩甙元溶液组合物
CN101177421B (zh) * 2006-11-07 2010-12-15 上海天伟生物制药有限公司 一种制备高纯度紫杉烷类化合物的方法
CN101081219B (zh) * 2007-07-10 2010-12-22 北京世纪博康医药科技有限公司 一种含紫杉烷类化合物的组合物、其制备方法和用途
US20110038899A1 (en) * 2008-03-28 2011-02-17 Garry Thomas Gwozdz Pharmaceutical Solutions and Method for Solublilizing Therapeutic Agents
US8420110B2 (en) 2008-03-31 2013-04-16 Cordis Corporation Drug coated expandable devices
US8409601B2 (en) 2008-03-31 2013-04-02 Cordis Corporation Rapamycin coated expandable devices
ES2344674B1 (es) 2008-08-07 2011-06-29 Gp Pharm, S.A. Composicion farmaceutica inyectable de taxanos.
US8541465B2 (en) 2009-10-19 2013-09-24 Scidose, Llc Docetaxel formulations with lipoic acid and/or dihydrolipoic acid
US8912228B2 (en) 2009-10-19 2014-12-16 Scidose Llc Docetaxel formulations with lipoic acid
US7772274B1 (en) 2009-10-19 2010-08-10 Scidose, Llc Docetaxel formulations with lipoic acid
JP5868414B2 (ja) * 2010-11-08 2016-02-24 カディラ ファーマシューティカルズ リミテッド タキソイドの医薬組成物
WO2012166795A1 (fr) * 2011-05-30 2012-12-06 String Therapeutics Inc. Procédés et compositions pour la surveillance et l'administration dosée d'un médicament thérapeutique par un profilage pharmaco-cinétique sur des lieux de soins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2404374A1 (fr) * 2000-03-24 2001-10-04 Baker Norton Pharmaceuticals, Inc. Utilisation de sels metalliques pour stabiliser des compositions a base de taxane

Also Published As

Publication number Publication date
KR20040081441A (ko) 2004-09-21
AU2002360816A1 (en) 2003-07-24
JP2005525310A (ja) 2005-08-25
EP1461029A1 (fr) 2004-09-29
WO2003057208A1 (fr) 2003-07-17
CN1615130A (zh) 2005-05-11

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued