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CA2463578A1 - Genes exprimes de maniere differentielle, associes a l'obesite et au diabete de type 2 - Google Patents

Genes exprimes de maniere differentielle, associes a l'obesite et au diabete de type 2 Download PDF

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Publication number
CA2463578A1
CA2463578A1 CA002463578A CA2463578A CA2463578A1 CA 2463578 A1 CA2463578 A1 CA 2463578A1 CA 002463578 A CA002463578 A CA 002463578A CA 2463578 A CA2463578 A CA 2463578A CA 2463578 A1 CA2463578 A1 CA 2463578A1
Authority
CA
Canada
Prior art keywords
agt
seq
nucleotide sequence
nucleic acid
acid molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002463578A
Other languages
English (en)
Inventor
Greg Collier
Paul Zev Zimmet
Ken Walder
Janine Mcmillan
Andrea Michelle De Silva
Kelly Windmill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deakin University
International Diabetes Institute
Autogen Research Pty Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2463578A1 publication Critical patent/CA2463578A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pathology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)

Abstract

L'invention concerne des molécules d'acides nucléiques codant des produits d'expression associés à la modulation de l'obésité, l'anorexie, du maintien du poids, du diabète et/ou des niveaux d'énergie métabolique. Les molécules d'acides nucléiques et les produits d'expression de l'invention sont produits à l'aide de moyens de recombinaison ou isolés dans des ressources naturelles. Les molécules d'acides nucléiques et les produits d'expression ainsi que leurs dérivés, homologues, analogues et mimétiques sont utilisés comme agents thérapeutiques et diagnostiques pour l'obésité, l'anorexie, le maintien du poids, le diabète et/ou le déséquilibre d'énergie ou comme cibles pour la conception et/ou l'identification de modulateurs de leur activité et/ou fonction. Les molécules d'acides nucléiques et les produits d'expression de l'invention sont identifiés à l'aide de techniques d'affichage différentiel.
CA002463578A 2001-10-16 2002-10-16 Genes exprimes de maniere differentielle, associes a l'obesite et au diabete de type 2 Abandoned CA2463578A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33014901P 2001-10-16 2001-10-16
US60/330,149 2001-10-16
PCT/AU2002/001405 WO2003033513A1 (fr) 2001-10-16 2002-10-16 Genes exprimes de maniere differentielle, associes a l'obesite et au diabete de type 2

Publications (1)

Publication Number Publication Date
CA2463578A1 true CA2463578A1 (fr) 2003-04-24

Family

ID=23288511

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002463578A Abandoned CA2463578A1 (fr) 2001-10-16 2002-10-16 Genes exprimes de maniere differentielle, associes a l'obesite et au diabete de type 2

Country Status (9)

Country Link
EP (1) EP1446414A4 (fr)
JP (1) JP2005510214A (fr)
KR (1) KR20040088019A (fr)
CN (1) CN1596264A (fr)
CA (1) CA2463578A1 (fr)
IL (1) IL161294A0 (fr)
MX (1) MXPA04003635A (fr)
WO (1) WO2003033513A1 (fr)
ZA (1) ZA200402859B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2513300A1 (fr) * 2003-01-13 2004-07-29 Autogen Research Pty Ltd Genes relatifs a l'obesite
DE10352510A1 (de) * 2003-11-07 2005-06-23 Forschungsinstitut Für Die Biologie Landwirtschaftlicher Nutztiere Verfahren zur Identifizierung von Wirkstoffen zur Beeinflussung der Körpermasse und des Fettansatzes
US7635559B2 (en) 2003-12-24 2009-12-22 Samsung Electronics Co., Ltd. Polynucleotide associated with a type II diabetes mellitus comprising single nucleotide polymorphism, microarray and diagnostic kit comprising the same and method for analyzing polynucleotide using the same
WO2005090378A1 (fr) * 2004-03-16 2005-09-29 Agt Biosciences Limited Ligands de la molecule fit (agt-121) et leur utilisation pharmaceutique
WO2006063009A2 (fr) * 2004-12-07 2006-06-15 Ohio University Diagnostic de l'hyperinsulinemie et du diabete de type ii et protection contre ceux-ci sur la base de proteines exprimees differemment dans le serum
CN116042819A (zh) * 2021-06-28 2023-05-02 东莞市寮步医院 hsa_circ_0002490在制备肝癌检测或疗效评价产品中的应用
CN114958875B (zh) * 2022-05-15 2023-08-18 赣南师范大学 柑橘黄龙病菌内参基因metG筛选和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2780405B1 (fr) * 1998-06-25 2001-12-28 Centre Nat Rech Scient Nouveaux recepteurs olfactifs et leurs utilisations
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides

Also Published As

Publication number Publication date
JP2005510214A (ja) 2005-04-21
KR20040088019A (ko) 2004-10-15
MXPA04003635A (es) 2004-07-30
EP1446414A4 (fr) 2005-11-23
ZA200402859B (en) 2005-01-24
IL161294A0 (en) 2004-09-27
WO2003033513A1 (fr) 2003-04-24
CN1596264A (zh) 2005-03-16
EP1446414A1 (fr) 2004-08-18

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued