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CA2339406A1 - Nouveau polypeptide esk du canal potassium et compositions polynucleotidiques - Google Patents

Nouveau polypeptide esk du canal potassium et compositions polynucleotidiques Download PDF

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Publication number
CA2339406A1
CA2339406A1 CA002339406A CA2339406A CA2339406A1 CA 2339406 A1 CA2339406 A1 CA 2339406A1 CA 002339406 A CA002339406 A CA 002339406A CA 2339406 A CA2339406 A CA 2339406A CA 2339406 A1 CA2339406 A1 CA 2339406A1
Authority
CA
Canada
Prior art keywords
esk
sequence
seq
polypeptide
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002339406A
Other languages
English (en)
Inventor
John R. Forsayeth
Byron B. Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elan Pharmaceuticals LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2339406A1 publication Critical patent/CA2339406A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne une nouvelle sous-unité (ESK) du canal potassium et des polynucléotides identifiant et codant ESK. L'invention concerne également des vecteurs d'expression et des cellules hôtes comprenant une séquence d'acide nucléique codant ESK. L'invention concerne en outre des anticorps d'ESK et des méthodes de diagnostic et de traitement d'affections liées à l'expression d'ESK, ainsi que des dosages biologiques de criblage faisant appel aux compositions de polypeptides, de nucléotides et d'anticorps.
CA002339406A 1998-08-14 1999-08-13 Nouveau polypeptide esk du canal potassium et compositions polynucleotidiques Abandoned CA2339406A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9657098P 1998-08-14 1998-08-14
US60/096,570 1998-08-14
PCT/US1999/018556 WO2000009534A1 (fr) 1998-08-14 1999-08-13 Nouveau polypeptide esk du canal potassium et compositions polynucleotidiques

Publications (1)

Publication Number Publication Date
CA2339406A1 true CA2339406A1 (fr) 2000-02-24

Family

ID=22257998

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002339406A Abandoned CA2339406A1 (fr) 1998-08-14 1999-08-13 Nouveau polypeptide esk du canal potassium et compositions polynucleotidiques

Country Status (5)

Country Link
EP (1) EP1105406A4 (fr)
JP (1) JP2003527818A (fr)
AU (1) AU5487199A (fr)
CA (1) CA2339406A1 (fr)
WO (1) WO2000009534A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094948B2 (en) 2001-11-14 2006-08-22 Astellas Pharma, Inc. Transgenic animals
US8399663B2 (en) 2009-04-03 2013-03-19 Astellas Pharma Inc. Salt of 1,3,5-triazine-2,4,6-triamine derivative
JPWO2010137689A1 (ja) * 2009-05-29 2012-11-15 アステラス製薬株式会社 注意欠陥/多動性障害新規予防用及び/又は治療用医薬組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401629A (en) * 1990-08-07 1995-03-28 The Salk Institute Biotechnology/Industrial Associates, Inc. Assay methods and compositions useful for measuring the transduction of an intracellular signal
US5328830A (en) * 1992-09-08 1994-07-12 Miles Inc. Potassium channel modulators
US5599673A (en) * 1995-03-09 1997-02-04 University Of Utah Research Foundation Long QT syndrome genes
US5565483A (en) * 1995-06-07 1996-10-15 Bristol-Myers Squibb Company 3-substituted oxindole derivatives as potassium channel modulators
AU1982799A (en) * 1998-01-23 1999-08-09 Yamanouchi Pharmaceutical Co., Ltd. Novel potassium channel protein

Also Published As

Publication number Publication date
WO2000009534A1 (fr) 2000-02-24
EP1105406A4 (fr) 2004-12-15
JP2003527818A (ja) 2003-09-24
EP1105406A1 (fr) 2001-06-13
AU5487199A (en) 2000-03-06

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