CA2339047A1 - Proteines secretees et polynucleotides les codant - Google Patents
Proteines secretees et polynucleotides les codant Download PDFInfo
- Publication number
- CA2339047A1 CA2339047A1 CA002339047A CA2339047A CA2339047A1 CA 2339047 A1 CA2339047 A1 CA 2339047A1 CA 002339047 A CA002339047 A CA 002339047A CA 2339047 A CA2339047 A CA 2339047A CA 2339047 A1 CA2339047 A1 CA 2339047A1
- Authority
- CA
- Canada
- Prior art keywords
- seq
- nucleotide sequence
- nucleotide
- amino acid
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 922
- 102000004169 proteins and genes Human genes 0.000 title claims abstract description 909
- 102000040430 polynucleotide Human genes 0.000 title claims abstract description 772
- 108091033319 polynucleotide Proteins 0.000 title claims abstract description 771
- 239000002157 polynucleotide Substances 0.000 title claims abstract description 771
- 239000002773 nucleotide Substances 0.000 claims description 1582
- 125000003729 nucleotide group Chemical group 0.000 claims description 1582
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 651
- 239000012634 fragment Substances 0.000 claims description 476
- 239000002299 complementary DNA Substances 0.000 claims description 325
- 150000001413 amino acids Chemical class 0.000 claims description 266
- 108091026890 Coding region Proteins 0.000 claims description 174
- 238000000034 method Methods 0.000 claims description 79
- 210000004027 cell Anatomy 0.000 claims description 6
- 125000003835 nucleoside group Chemical group 0.000 claims description 2
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 claims 320
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 230000004071 biological effect Effects 0.000 description 65
- 108020004414 DNA Proteins 0.000 description 41
- 239000000523 sample Substances 0.000 description 39
- 108091036407 Polyadenylation Proteins 0.000 description 38
- 108091028043 Nucleic acid sequence Proteins 0.000 description 14
- 241000894007 species Species 0.000 description 13
- 238000010367 cloning Methods 0.000 description 4
- 238000009396 hybridization Methods 0.000 description 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 3
- 238000012411 cloning technique Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000001400 expression cloning Methods 0.000 description 2
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 102000015696 Interleukins Human genes 0.000 description 1
- 108010063738 Interleukins Proteins 0.000 description 1
- 102000008072 Lymphokines Human genes 0.000 description 1
- 108010074338 Lymphokines Proteins 0.000 description 1
- 108010076504 Protein Sorting Signals Proteins 0.000 description 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 1
- 229940047124 interferons Drugs 0.000 description 1
- 229940047122 interleukins Drugs 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La présente invention concerne des polynucléotides nouvellement découverts ainsi que des protéines codées par de tels polynucléotides.
Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9662298P | 1998-08-14 | 1998-08-14 | |
| US9681598P | 1998-08-17 | 1998-08-17 | |
| US9922998P | 1998-09-04 | 1998-09-04 | |
| US10536898P | 1998-10-23 | 1998-10-23 | |
| US11523499P | 1999-01-08 | 1999-01-08 | |
| US11993199P | 1999-02-12 | 1999-02-12 | |
| US12057599P | 1999-02-18 | 1999-02-18 | |
| US13202099P | 1999-04-30 | 1999-04-30 | |
| US14842499P | 1999-08-11 | 1999-08-11 | |
| US60/096,622 | 1999-08-11 | ||
| US60/148,424 | 1999-08-11 | ||
| US60/119,931 | 1999-08-11 | ||
| US60/096,815 | 1999-08-11 | ||
| US60/115,234 | 1999-08-11 | ||
| US60/132,020 | 1999-08-11 | ||
| US60/120,575 | 1999-08-11 | ||
| US60/099,229 | 1999-08-11 | ||
| US60/105,368 | 1999-08-11 | ||
| PCT/US1999/018298 WO2000009552A1 (fr) | 1998-08-14 | 1999-08-13 | Proteines secretees et polynucleotides les codant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2339047A1 true CA2339047A1 (fr) | 2000-02-24 |
Family
ID=27578412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002339047A Abandoned CA2339047A1 (fr) | 1998-08-14 | 1999-08-13 | Proteines secretees et polynucleotides les codant |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1112286A1 (fr) |
| JP (1) | JP2002522062A (fr) |
| CA (1) | CA2339047A1 (fr) |
| WO (1) | WO2000009552A1 (fr) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1072610B1 (fr) | 1998-04-14 | 2010-07-21 | Chugai Seiyaku Kabushiki Kaisha | Nouvelle proteine du type cytokine |
| US7109292B2 (en) * | 1999-03-08 | 2006-09-19 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US7034132B2 (en) | 2001-06-04 | 2006-04-25 | Anderson David W | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| CA2377263A1 (fr) * | 1999-06-23 | 2000-12-28 | Curagen Corporation | Polypeptides et polynucleotides les codants |
| WO2001012659A2 (fr) * | 1999-08-18 | 2001-02-22 | Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. | Sequence d'adn humain |
| WO2001014550A1 (fr) * | 1999-08-19 | 2001-03-01 | Genset | Gene 3 lie au cancer de la prostate (pg-3) et marqueurs bialleliques |
| WO2001023567A1 (fr) * | 1999-09-28 | 2001-04-05 | Zymogenetics, Inc. | Proteine-60 membranaire |
| FR2801056B1 (fr) | 1999-11-12 | 2003-03-28 | Commissariat Energie Atomique | Proteine presente a la surface des cellules souches hematopoietiques de la lignee lymphoide et des cellules nk, et ses applications |
| EP1282635A4 (fr) * | 2000-05-18 | 2005-05-11 | Nuvelo Inc | Nouveaux acides nucleiques et polypeptides |
| US20040132646A1 (en) * | 2000-07-28 | 2004-07-08 | Klaus Duecker | Identification of a novel glutamine transporter |
| WO2002016599A2 (fr) * | 2000-08-25 | 2002-02-28 | Curagen Corporation | Nouvelles proteines et acides nucleiques les codant |
| WO2002062945A2 (fr) | 2000-10-25 | 2002-08-15 | Diadexus, Inc. | Compositions et techniques relatives a des genes et a des proteines specifiques du poumon |
| CA2428140A1 (fr) * | 2000-11-08 | 2002-05-16 | Incyte Genomics, Inc. | Proteines secretees |
| US7608704B2 (en) | 2000-11-08 | 2009-10-27 | Incyte Corporation | Secreted proteins |
| WO2002057457A2 (fr) * | 2000-12-18 | 2002-07-25 | Millennium Pharmaceuticals, Inc. | 55562 et 21617, nouvelles proteines humaines et leurs methodes d'utilisation |
| US20040163137A1 (en) * | 2001-02-20 | 2004-08-19 | Caroline Barry | PG-3 and biallelic markers thereof |
| US7247711B2 (en) | 2003-05-09 | 2007-07-24 | Centocor, Inc. | IL-23p40 specific antibody |
| AR051444A1 (es) | 2004-09-24 | 2007-01-17 | Centocor Inc | Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos |
| PT1896073E (pt) | 2005-06-30 | 2013-05-28 | Janssen Biotech Inc | Composições, métodos e aplicações de anticorpos anti-il-23 |
| WO2007019426A2 (fr) * | 2005-08-05 | 2007-02-15 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Nouveau peptide intervenant dans l'homeostasie energetique |
| AU2006330411B2 (en) | 2005-12-29 | 2012-07-12 | Janssen Biotech, Inc. | Human anti-IL-23 antibodies, compositions, methods and uses |
| BR112021009287A2 (pt) | 2018-11-20 | 2021-10-26 | Janssen Biotech, Inc. | Método seguro e eficaz para tratar psoríase com anticorpo específico anti-il-23 |
| CA3138241A1 (fr) | 2019-05-23 | 2020-11-26 | Janssen Biotech, Inc. | Methode de traitement de maladie intestinale inflammatoire au moyen d'une polytherapie d'anticorps diriges contre il -23 et tnf alpha |
| EP4596046A3 (fr) | 2020-05-21 | 2025-10-22 | Janssen Biotech, Inc. | Procédé de traitement d'une maladie intestinale inflammatoire avec une polythérapie d'anticorps dirigés contre il-23 et tnf alpha |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0973896A2 (fr) * | 1997-04-10 | 2000-01-26 | Genetics Institute, Inc. | Marqueurs secretes de sequence exprimee (sest) |
-
1999
- 1999-08-13 CA CA002339047A patent/CA2339047A1/fr not_active Abandoned
- 1999-08-13 JP JP2000565001A patent/JP2002522062A/ja not_active Withdrawn
- 1999-08-13 EP EP99942123A patent/EP1112286A1/fr not_active Withdrawn
- 1999-08-13 WO PCT/US1999/018298 patent/WO2000009552A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000009552A1 (fr) | 2000-02-24 |
| WO2000009552A9 (fr) | 2002-02-14 |
| JP2002522062A (ja) | 2002-07-23 |
| EP1112286A1 (fr) | 2001-07-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |