CA2335292A1 - Antagonistes des recepteurs d'il-8 - Google Patents
Antagonistes des recepteurs d'il-8 Download PDFInfo
- Publication number
- CA2335292A1 CA2335292A1 CA002335292A CA2335292A CA2335292A1 CA 2335292 A1 CA2335292 A1 CA 2335292A1 CA 002335292 A CA002335292 A CA 002335292A CA 2335292 A CA2335292 A CA 2335292A CA 2335292 A1 CA2335292 A1 CA 2335292A1
- Authority
- CA
- Canada
- Prior art keywords
- alkyl
- optionally substituted
- heteroaryl
- cr8r8
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 108010038415 interleukin-8 receptors Proteins 0.000 title description 6
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 27
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- 125000001072 heteroaryl group Chemical group 0.000 claims description 95
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
L'invention se rapporte à de nouveaux composés représentés par la formule (I), et à des compositions contenant ces composés, qui s'avèrent utiles pour le traitement des états pathologiques liés à une médiation assurée par la chimiokine Interleukine-8 (IL-8).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8963398P | 1998-06-17 | 1998-06-17 | |
| US60/089,633 | 1998-06-17 | ||
| PCT/US1999/013739 WO1999065310A1 (fr) | 1998-06-17 | 1999-06-17 | Antagonistes des recepteurs d'il-8 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2335292A1 true CA2335292A1 (fr) | 1999-12-23 |
Family
ID=22218727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002335292A Abandoned CA2335292A1 (fr) | 1998-06-17 | 1999-06-17 | Antagonistes des recepteurs d'il-8 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1087661A4 (fr) |
| JP (1) | JP2002518300A (fr) |
| CA (1) | CA2335292A1 (fr) |
| WO (1) | WO1999065310A1 (fr) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5874080A (en) * | 1994-03-03 | 1999-02-23 | Genentech, Inc. | Anti-IL-8 monoclonal antibodies for treatment of asthma |
| EP0809492A4 (fr) * | 1995-02-17 | 2007-01-24 | Smithkline Beecham Corp | Antagonistes des recepteurs d'il-8 |
| IL127666A0 (en) * | 1996-06-27 | 1999-10-28 | Smithkline Beecham Corp | IL-8 receptor antagonists |
| CN1217660C (zh) * | 1997-01-23 | 2005-09-07 | 史密丝克莱恩比彻姆公司 | Il－8受体拮抗剂 |
-
1999
- 1999-06-17 CA CA002335292A patent/CA2335292A1/fr not_active Abandoned
- 1999-06-17 EP EP99928764A patent/EP1087661A4/fr not_active Withdrawn
- 1999-06-17 JP JP2000554201A patent/JP2002518300A/ja active Pending
- 1999-06-17 WO PCT/US1999/013739 patent/WO1999065310A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1087661A4 (fr) | 2003-04-16 |
| EP1087661A1 (fr) | 2001-04-04 |
| JP2002518300A (ja) | 2002-06-25 |
| WO1999065310A1 (fr) | 1999-12-23 |
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| Date | Code | Title | Description |
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| FZDE | Dead |