CA2324281A1 - Systeme de reacteur multi-site a commande dynamique independante de sites de reaction individuels - Google Patents
Systeme de reacteur multi-site a commande dynamique independante de sites de reaction individuels Download PDFInfo
- Publication number
- CA2324281A1 CA2324281A1 CA002324281A CA2324281A CA2324281A1 CA 2324281 A1 CA2324281 A1 CA 2324281A1 CA 002324281 A CA002324281 A CA 002324281A CA 2324281 A CA2324281 A CA 2324281A CA 2324281 A1 CA2324281 A1 CA 2324281A1
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- temperature
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B13/00—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion
- G05B13/02—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
- G05B13/0205—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric not using a model or a simulator of the controlled system
- G05B13/021—Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric not using a model or a simulator of the controlled system in which a variable is automatically adjusted to optimise the performance
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D23/00—Control of temperature
- G05D23/19—Control of temperature characterised by the use of electric means
- G05D23/1906—Control of temperature characterised by the use of electric means using an analogue comparing device
- G05D23/1913—Control of temperature characterised by the use of electric means using an analogue comparing device delivering a series of pulses
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Automation & Control Theory (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Software Systems (AREA)
- Clinical Laboratory Science (AREA)
- Artificial Intelligence (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Evolutionary Computation (AREA)
- Medical Informatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Control Of Temperature (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
L'invention concerne un système de réacteur multi-site (60) présentant une commande dynamique, indépendante et informatisée de chaque site de réaction, et permettant de réaliser différents profils thermiques sur des échantillons, simultanément en différents sites de réaction. Le système comprend des récipients réactionnels (2) destinés à contenir des mélanges réactionnels, et des modules échangeurs thermiques (37) destinés à recevoir lesdits récipients. Chaque module échangeur thermique (37) comprend une paire de plaques thermiques entre lesquelles l'un des récipients (2) est inséré, des éléments de chauffage couplés à une ou deux plaques, pour le chauffage du mélange réactionnel contenu dans le récipient, un ventilateur pour le refroidissement de la plaque et du mélange, ainsi qu'un détecteur de température pour la mesure de la température de la plaque. Le système comprend également un régulateur (64) pour commander indépendamment chaque module échangeur thermique (37) en vue de chauffer et/ou de refroidir le mélange réactionnel qu'il contient. Le régulateur (64) comprend un programme de régulation adaptable en vue de régler dynamiquement la durée ou l'intensité des impulsions d'énergie fournies à chaque élément de chauffage et de régler dynamiquement la durée de fonctionnement du ventilateur afin d'atteindre rapidement et avec précision les températures cibles sans dépassement ni sous-dépassement de la valeur cible.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4642098A | 1998-03-23 | 1998-03-23 | |
| US09/046,420 | 1998-03-23 | ||
| PCT/US1999/006628 WO1999048608A2 (fr) | 1998-03-23 | 1999-03-23 | Systeme de reacteur multi-site a commande dynamique independante de sites de reaction individuels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2324281A1 true CA2324281A1 (fr) | 1999-09-30 |
Family
ID=21943355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002324281A Abandoned CA2324281A1 (fr) | 1998-03-23 | 1999-03-23 | Systeme de reacteur multi-site a commande dynamique independante de sites de reaction individuels |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1066551A2 (fr) |
| JP (1) | JP2002507815A (fr) |
| AU (1) | AU743740B2 (fr) |
| CA (1) | CA2324281A1 (fr) |
| WO (1) | WO1999048608A2 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112934142A (zh) * | 2021-02-01 | 2021-06-11 | 山东大学 | 一种基于反步法的均相管式反应器温度控制方法及系统 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6660228B1 (en) | 1998-03-02 | 2003-12-09 | Cepheid | Apparatus for performing heat-exchanging, chemical reactions |
| GB9915953D0 (en) * | 1999-07-07 | 1999-09-08 | Stem Corp Limited | Improvements relating to multi-station reaction apparatus |
| US6699713B2 (en) | 2000-01-04 | 2004-03-02 | The Regents Of The University Of California | Polymerase chain reaction system |
| US6403037B1 (en) | 2000-02-04 | 2002-06-11 | Cepheid | Reaction vessel and temperature control system |
| US6783934B1 (en) * | 2000-05-01 | 2004-08-31 | Cepheid, Inc. | Methods for quantitative analysis of nucleic acid amplification reaction |
| FR2829338B1 (fr) * | 2001-09-03 | 2003-10-31 | Schneider Automation | Equipement d'automatisme equipe d'une liaison de type usb |
| GB2399776A (en) * | 2003-03-24 | 2004-09-29 | Pa Knowledge Ltd | Cyclical heating and cooling device and associated methods |
| JP4705035B2 (ja) | 2003-05-23 | 2011-06-22 | バイオ−ラッド ラボラトリーズ，インコーポレイティド | 反応培地の空間配列に対し局部化した温度制御 |
| GB2404098A (en) * | 2003-07-14 | 2005-01-19 | Reckitt Benckiser | Controller for heater of a chemical vaporiser |
| CN101802163A (zh) * | 2007-05-23 | 2010-08-11 | 信诚医疗有限公司 | 反应液用容器，使用这种容器的反应促进装置，及其方法 |
| WO2009024956A1 (fr) * | 2007-08-17 | 2009-02-26 | James Walsh | Ensemble de récipients et son procédé de production |
| EP2060324A1 (fr) * | 2007-11-13 | 2009-05-20 | F.Hoffmann-La Roche Ag | Unité de bloc thermique |
| EP2108451A1 (fr) * | 2008-04-11 | 2009-10-14 | Eppendorf AG | Dispositif d'exécution de réactions dans des échantillons |
| CN103543282A (zh) * | 2010-07-23 | 2014-01-29 | 贝克曼考尔特公司 | 用于处理化验盒的系统 |
| JP6717195B2 (ja) * | 2014-09-26 | 2020-07-01 | 東洋紡株式会社 | 反応促進装置及び核酸検査装置 |
| CN115145329B (zh) * | 2021-07-16 | 2023-11-28 | 武汉帝尔激光科技股份有限公司 | 一种用于电池片激光加工的温度控制系统及温度控制方法 |
| JP2024535381A (ja) * | 2021-09-23 | 2024-09-30 | エヌシックス・テック、インコーポレイテッド | 試料分析のための方法およびシステム |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02132502A (ja) * | 1988-07-28 | 1990-05-22 | Omron Tateisi Electron Co | ファジィ制御装置における動作方法および調整装置 |
| US5207987A (en) * | 1990-05-21 | 1993-05-04 | Pb Diagnostic Systems Inc. | Temperature controlled chamber for diagnostic analyzer |
| US5180896A (en) * | 1990-10-11 | 1993-01-19 | University Of Florida | System and method for in-line heating of medical fluid |
| US5088098A (en) * | 1990-10-16 | 1992-02-11 | General Instrument Corporation | Thermoelectric cooler control circuit |
| US5687077A (en) * | 1991-07-31 | 1997-11-11 | Universal Dynamics Limited | Method and apparatus for adaptive control |
| AT400201B (de) * | 1991-11-11 | 1995-11-27 | Vaillant Gmbh | Verfahren zum betreiben einer regeleinrichtung und vorrichtung zu seiner durchführung |
| FI915731A0 (fi) * | 1991-12-05 | 1991-12-05 | Derek Henry Potter | Foerfarande och anordning foer reglering av temperaturen i ett flertal prov. |
| DE4319652C2 (de) * | 1993-06-14 | 2002-08-08 | Perkin Elmer Bodenseewerk Zwei | Verfahren zur Temperatursteuerung |
| US5415346A (en) * | 1994-01-28 | 1995-05-16 | American Standard Inc. | Apparatus and method for reducing overshoot in response to the setpoint change of an air conditioning system |
| US5371665A (en) * | 1994-03-14 | 1994-12-06 | Quisenberry; Tony M. | Power control circuit for improved power application and temperature control of thermoelectric coolers and method for controlling thereof |
| US5589136A (en) * | 1995-06-20 | 1996-12-31 | Regents Of The University Of California | Silicon-based sleeve devices for chemical reactions |
| EP2333520B1 (fr) * | 1997-02-28 | 2014-06-25 | Cepheid | Ensemble pour réaction chimique avec échange thermique et analyse optique |
| CA2285377C (fr) * | 1997-03-28 | 2004-08-17 | The Perkin-Elmer Corporation | Ameliorations apportees a un cycleur thermique pour pcr |
-
1999
- 1999-03-23 WO PCT/US1999/006628 patent/WO1999048608A2/fr not_active Ceased
- 1999-03-23 AU AU32065/99A patent/AU743740B2/en not_active Expired
- 1999-03-23 CA CA002324281A patent/CA2324281A1/fr not_active Abandoned
- 1999-03-23 EP EP99914164A patent/EP1066551A2/fr not_active Withdrawn
- 1999-03-23 JP JP2000537649A patent/JP2002507815A/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112934142A (zh) * | 2021-02-01 | 2021-06-11 | 山东大学 | 一种基于反步法的均相管式反应器温度控制方法及系统 |
| CN112934142B (zh) * | 2021-02-01 | 2023-06-06 | 山东大学 | 一种基于反步法的均相管式反应器温度控制方法及系统 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999048608A2 (fr) | 1999-09-30 |
| JP2002507815A (ja) | 2002-03-12 |
| WO1999048608A3 (fr) | 1999-12-09 |
| EP1066551A2 (fr) | 2001-01-10 |
| AU3206599A (en) | 1999-10-18 |
| AU743740B2 (en) | 2002-02-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |