CA2309996A1 - Appareil d'administration de fluide - Google Patents
Appareil d'administration de fluide Download PDFInfo
- Publication number
- CA2309996A1 CA2309996A1 CA002309996A CA2309996A CA2309996A1 CA 2309996 A1 CA2309996 A1 CA 2309996A1 CA 002309996 A CA002309996 A CA 002309996A CA 2309996 A CA2309996 A CA 2309996A CA 2309996 A1 CA2309996 A1 CA 2309996A1
- Authority
- CA
- Canada
- Prior art keywords
- inlet
- valve
- conduit
- outlet
- gas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000012530 fluid Substances 0.000 title claims abstract description 56
- 239000012190 activator Substances 0.000 claims abstract description 7
- 239000000126 substance Substances 0.000 claims description 17
- 238000002595 magnetic resonance imaging Methods 0.000 claims description 15
- 238000003384 imaging method Methods 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 8
- 239000004033 plastic Substances 0.000 claims description 8
- 229920003023 plastic Polymers 0.000 claims description 8
- 238000013022 venting Methods 0.000 claims description 8
- 239000011521 glass Substances 0.000 claims description 4
- 239000000696 magnetic material Substances 0.000 claims description 4
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 3
- 230000008602 contraction Effects 0.000 claims description 3
- 239000010936 titanium Substances 0.000 claims description 3
- 229910052719 titanium Inorganic materials 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 238000010276 construction Methods 0.000 claims description 2
- 239000012216 imaging agent Substances 0.000 claims description 2
- 238000004054 3He NMR spectroscopy Methods 0.000 claims 1
- 239000007789 gas Substances 0.000 description 108
- 230000029058 respiratory gaseous exchange Effects 0.000 description 24
- 230000005291 magnetic effect Effects 0.000 description 20
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 10
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 10
- 239000001301 oxygen Substances 0.000 description 9
- 229910052760 oxygen Inorganic materials 0.000 description 9
- 210000002345 respiratory system Anatomy 0.000 description 8
- 230000005284 excitation Effects 0.000 description 7
- 239000007788 liquid Substances 0.000 description 7
- 210000004072 lung Anatomy 0.000 description 7
- 239000000463 material Substances 0.000 description 6
- 239000000203 mixture Substances 0.000 description 5
- 229910052757 nitrogen Inorganic materials 0.000 description 4
- 238000005481 NMR spectroscopy Methods 0.000 description 3
- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 description 3
- 230000010287 polarization Effects 0.000 description 3
- 230000002269 spontaneous effect Effects 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 229910002092 carbon dioxide Inorganic materials 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 229910001873 dinitrogen Inorganic materials 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 238000011010 flushing procedure Methods 0.000 description 2
- 230000004907 flux Effects 0.000 description 2
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical group [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 2
- 230000002102 hyperpolarization Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 230000002040 relaxant effect Effects 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 210000003437 trachea Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000270322 Lepidosauria Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 239000003994 anesthetic gas Substances 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000012611 container material Substances 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005294 ferromagnetic effect Effects 0.000 description 1
- -1 for example Substances 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-BJUDXGSMSA-N helium-3 atom Chemical compound [3He] SWQJXJOGLNCZEY-BJUDXGSMSA-N 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 239000006194 liquid suspension Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 239000000693 micelle Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000012811 non-conductive material Substances 0.000 description 1
- 230000005298 paramagnetic effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000000264 spin echo pulse sequence Methods 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000003325 tomography Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Measuring devices for evaluating the respiratory organs
- A61B5/0813—Measurement of pulmonary parameters by tracers, e.g. radioactive tracers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
- A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
- A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Surgery (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Radiology & Medical Imaging (AREA)
- High Energy & Nuclear Physics (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physiology (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Indicating Or Recording The Presence, Absence, Or Direction Of Movement (AREA)
- Loading And Unloading Of Fuel Tanks Or Ships (AREA)
Abstract
L'invention porte sur un appareil d'administration de fluide comprenant: un réservoir de fluide à volume variable et un conduit d'acheminement du fluide conduisant à un orifice d'évacuation du fluide, à un premier orifice d'admission et à un second orifice d'admission du fluide; un premier détecteur disposé de façon à détecter l'écoulement de fluide entre le conduit et le réservoir; une première soupape permettant ou empêchant l'écoulement de fluide dans le conduit, du premier orifice d'admission au réservoir; une seconde soupape qui, lors d'un premier réglage, permet au fluide de s'écouler dans le conduit du second orifice d'admission à l'orifice d'évacuation, et qui empêche le fluide de s'écouler également dans le conduit, du réservoir à l'orifice d'évacuation, et, lors d'un second réglage, permet l'écoulement du fluide dans le conduit, du réservoir à l'orifice d'évacuation, et empêche l'écoulement du fluide dans le conduit, du second orifice d'admission à l'orifice d'évacuation; et un second détecteur qui détecte l'écoulement de fluide dans le conduit provenant du second orifice d'admission, et un activateur conçu de façon à commander le fonctionnement des première et seconde soupapes.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19750467 | 1997-11-14 | ||
| DE19750467.1 | 1998-03-28 | ||
| DE19813790 | 1998-03-28 | ||
| DE19813790.7 | 1998-03-28 | ||
| PCT/EP1998/007516 WO1999025243A1 (fr) | 1997-11-14 | 1998-11-13 | Appareil d'administration de fluide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2309996A1 true CA2309996A1 (fr) | 1999-05-27 |
Family
ID=26041596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002309996A Abandoned CA2309996A1 (fr) | 1997-11-14 | 1998-11-13 | Appareil d'administration de fluide |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1030594A1 (fr) |
| JP (1) | JP2001522681A (fr) |
| CN (1) | CN1281345A (fr) |
| AU (1) | AU1874399A (fr) |
| BR (1) | BR9814968A (fr) |
| CA (1) | CA2309996A1 (fr) |
| HU (1) | HUP0100529A2 (fr) |
| IL (1) | IL136116A0 (fr) |
| NO (1) | NO20002478L (fr) |
| PL (1) | PL340503A1 (fr) |
| WO (1) | WO1999025243A1 (fr) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6128918A (en) * | 1998-07-30 | 2000-10-10 | Medi-Physics, Inc. | Containers for hyperpolarized gases and associated methods |
| US6423387B1 (en) | 1998-06-17 | 2002-07-23 | Medi-Physics, Inc. | Resilient containers for hyperpolarized gases and associated methods |
| NZ508719A (en) | 1998-06-17 | 2002-10-25 | Medi Physics Inc | Hyperpolarized gas transport device with at least one gas chamber and a electromagnet providing a magnetic holding field |
| US6523356B2 (en) | 1998-09-30 | 2003-02-25 | Medi-Physics, Inc. | Meted hyperpolarized noble gas dispensing methods and associated devices |
| US6286319B1 (en) * | 1998-09-30 | 2001-09-11 | Medi-Physics, Inc. | Meted hyperpolarized noble gas dispensing methods and associated devices |
| US6237363B1 (en) | 1998-09-30 | 2001-05-29 | Medi-Physics, Inc. | Hyperpolarized noble gas extraction methods masking methods and associated transport containers |
| US6284222B1 (en) | 1998-11-03 | 2001-09-04 | Medi--Physics, Inc. | Hyperpolarized helium-3 microbubble gas entrapment methods |
| US6566875B1 (en) | 1999-02-23 | 2003-05-20 | Medi-Physics, Inc. | Portable hyperpolarized gas monitoring systems, computer program products, and related methods using NMR and/or MRI during transport |
| US6295834B1 (en) | 1999-06-30 | 2001-10-02 | Medi-Physics, Inc. | NMR polarization monitoring coils, hyperpolarizers with same, and methods for determining the polarization level of accumulated hyperpolarized noble gases during production |
| US6648130B1 (en) | 1999-08-11 | 2003-11-18 | Medi-Physics, Inc. | Hyperpolarized gas transport and storage devices and associated transport and storage methods using permanent magnets |
| JP2003509130A (ja) * | 1999-09-16 | 2003-03-11 | ザ ジョンズ ホプキンズ ユニバーシティ | 高磁場および/またはrf環境下で使用する装置用の分散型アーキテクチャ |
| CA2401308A1 (fr) | 2000-03-13 | 2001-09-20 | Klaus D. Hagspiel | Procedures de diagnostic utilisant une injection directe de xe129 hyperpolarise, et produits et systemes associes |
| US6696040B2 (en) | 2000-07-13 | 2004-02-24 | Medi-Physics, Inc. | Diagnostic procedures using 129Xe spectroscopy characteristic chemical shift to detect pathology in vivo |
| US7179450B2 (en) | 2001-09-20 | 2007-02-20 | Medi-Physics, Inc. | Methods for in vivo evaluation of pulmonary physiology and/or function using NMR signals of polarized Xe |
| ATE343760T1 (de) * | 2002-07-23 | 2006-11-15 | Medi Physics Inc | Automatisierte dynamische druckempfindliche systeme zur abgabe von hyperpolarisiertem gas und zugehörige verfahren und rechnerprogrammprodukte |
| CA2515467A1 (fr) * | 2003-02-26 | 2004-09-10 | Medi-Physics Inc. | Soupapes de distribution de gaz hyperpolarises compatibles irm/rmn destinees a des ventilateurs et procedes de distribution de gaz associes |
| US7275540B2 (en) * | 2003-04-22 | 2007-10-02 | Medi-Physics, Inc. | MRI/NMR-compatible, tidal volume control and measurement systems, methods, and devices for respiratory and hyperpolarized gas delivery |
| CN103495251B (zh) * | 2013-07-18 | 2016-01-20 | 中国科学院武汉物理与数学研究所 | 一种非麻醉状态下人体超极化气体呼吸装置 |
| WO2021224923A1 (fr) * | 2020-05-05 | 2021-11-11 | Hospitech Respiration Ltd. | Dispositif de distribution de fluide |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3666955A (en) * | 1970-07-08 | 1972-05-30 | Edgar L Suprenant | Automatic control system for radioactive regional ventilation studies |
| US4169465A (en) * | 1977-05-04 | 1979-10-02 | James A. Walls | Method and apparatus for obtaining non-invasive cardio-pulmonary measurements |
| US4810392A (en) * | 1987-04-17 | 1989-03-07 | W. R. Grace & Co. | Sample dispensing system for liquid chromatography |
| US4932401A (en) * | 1988-04-01 | 1990-06-12 | Perkins Warren E | Two-gas variable ratio, variable dose, metering system and method of use |
| US5370112A (en) * | 1993-07-01 | 1994-12-06 | Devilbiss Health Care, Inc. | Method and means for powering portable oxygen supply systems |
| US5545396A (en) | 1994-04-08 | 1996-08-13 | The Research Foundation Of State University Of New York | Magnetic resonance imaging using hyperpolarized noble gases |
| US5612103A (en) | 1995-06-07 | 1997-03-18 | Princeton University | Coatings for production of hyperpolarized noble gases |
| US5642625A (en) | 1996-03-29 | 1997-07-01 | The Trustees Of Princeton University | High volume hyperpolarizer for spin-polarized noble gas |
| JP2001503646A (ja) | 1996-03-29 | 2001-03-21 | ローレンス バークレー ナショナル ラボラトリィ | 過分極化希ガス存在下でのnmrまたはmriの増強 |
| DE19619471C1 (de) * | 1996-05-14 | 1997-10-16 | Siemens Ag | Kernspintomographiegerät mit Vorpolarisation |
-
1998
- 1998-11-13 PL PL98340503A patent/PL340503A1/xx unknown
- 1998-11-13 EP EP98963495A patent/EP1030594A1/fr not_active Withdrawn
- 1998-11-13 BR BR9814968-7A patent/BR9814968A/pt not_active Application Discontinuation
- 1998-11-13 AU AU18743/99A patent/AU1874399A/en not_active Abandoned
- 1998-11-13 CN CN98811897.1A patent/CN1281345A/zh active Pending
- 1998-11-13 HU HU0100529A patent/HUP0100529A2/hu unknown
- 1998-11-13 JP JP2000520685A patent/JP2001522681A/ja active Pending
- 1998-11-13 WO PCT/EP1998/007516 patent/WO1999025243A1/fr not_active Ceased
- 1998-11-13 IL IL13611698A patent/IL136116A0/xx unknown
- 1998-11-13 CA CA002309996A patent/CA2309996A1/fr not_active Abandoned
-
2000
- 2000-05-12 NO NO20002478A patent/NO20002478L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0100529A2 (hu) | 2001-06-28 |
| BR9814968A (pt) | 2000-10-03 |
| NO20002478D0 (no) | 2000-05-12 |
| IL136116A0 (en) | 2001-05-20 |
| EP1030594A1 (fr) | 2000-08-30 |
| PL340503A1 (en) | 2001-02-12 |
| WO1999025243A1 (fr) | 1999-05-27 |
| CN1281345A (zh) | 2001-01-24 |
| JP2001522681A (ja) | 2001-11-20 |
| NO20002478L (no) | 2000-07-13 |
| AU1874399A (en) | 1999-06-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |