CA2302788A1 - Improvements in or relating to capsules - Google Patents

Improvements in or relating to capsules Download PDF

Info

Publication number: CA2302788A1
Authority: CA; Canada
Prior art keywords: capsule; female body; charge; capsule according; male member
Prior art date: 1997-09-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002302788A

Other languages

English (en)

French (fr)

Inventor

Mark Hegarty

Gerard Atkins

Stephen Donald Mcfarlane

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Catalent Pharma Solutions Inc

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-04

Filing date

1998-09-02

Publication date

1999-03-11

1998-09-02 Application filed by Individual filed Critical Individual

1999-03-11 Publication of CA2302788A1 publication Critical patent/CA2302788A1/en

Status Abandoned legal-status Critical Current

Links

239000002775 capsule Substances 0.000 title claims abstract description 95
238000013270 controlled release Methods 0.000 claims abstract description 14
239000003795 chemical substances by application Substances 0.000 claims abstract description 11
239000007788 liquid Substances 0.000 claims description 20
239000000463 material Substances 0.000 claims description 18
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
238000012360 testing method Methods 0.000 claims description 12
238000001514 detection method Methods 0.000 claims description 3
239000006261 foam material Substances 0.000 claims description 2
244000005700 microbiome Species 0.000 claims description 2
239000007787 solid Substances 0.000 claims description 2
238000010276 construction Methods 0.000 abstract description 6
230000005484 gravity Effects 0.000 abstract description 2
230000008961 swelling Effects 0.000 abstract 1
-1 polyethylene Polymers 0.000 description 11
239000000017 hydrogel Substances 0.000 description 9
238000000338 in vitro Methods 0.000 description 7
239000011149 active material Substances 0.000 description 5
238000007598 dipping method Methods 0.000 description 5
239000000243 solution Substances 0.000 description 5
238000000034 method Methods 0.000 description 4
239000004743 Polypropylene Substances 0.000 description 3
238000003780 insertion Methods 0.000 description 3
230000037431 insertion Effects 0.000 description 3
229920001155 polypropylene Polymers 0.000 description 3
239000004800 polyvinyl chloride Substances 0.000 description 3
229920000915 polyvinyl chloride Polymers 0.000 description 3
238000010998 test method Methods 0.000 description 3
108010010803 Gelatin Proteins 0.000 description 2
239000004698 Polyethylene Substances 0.000 description 2
239000004793 Polystyrene Substances 0.000 description 2
229920002301 cellulose acetate Polymers 0.000 description 2
239000011248 coating agent Substances 0.000 description 2
238000000576 coating method Methods 0.000 description 2
238000004090 dissolution Methods 0.000 description 2
239000003814 drug Substances 0.000 description 2
229920000159 gelatin Polymers 0.000 description 2
239000008273 gelatin Substances 0.000 description 2
235000019322 gelatine Nutrition 0.000 description 2
235000011852 gelatine desserts Nutrition 0.000 description 2
239000008187 granular material Substances 0.000 description 2
238000001746 injection moulding Methods 0.000 description 2
229920001684 low density polyethylene Polymers 0.000 description 2
239000004702 low-density polyethylene Substances 0.000 description 2
229920001778 nylon Polymers 0.000 description 2
239000008188 pellet Substances 0.000 description 2
229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
229920000728 polyester Polymers 0.000 description 2
229920000573 polyethylene Polymers 0.000 description 2
239000004926 polymethyl methacrylate Substances 0.000 description 2
229920006324 polyoxymethylene Polymers 0.000 description 2
229920002223 polystyrene Polymers 0.000 description 2
229920001343 polytetrafluoroethylene Polymers 0.000 description 2
239000004810 polytetrafluoroethylene Substances 0.000 description 2
229920002635 polyurethane Polymers 0.000 description 2
239000004814 polyurethane Substances 0.000 description 2
238000005507 spraying Methods 0.000 description 2
239000003826 tablet Substances 0.000 description 2
239000012815 thermoplastic material Substances 0.000 description 2
239000001856 Ethyl cellulose Substances 0.000 description 1
ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 1
241000237858 Gastropoda Species 0.000 description 1
241001465754 Metazoa Species 0.000 description 1
239000000020 Nitrocellulose Substances 0.000 description 1
239000004677 Nylon Substances 0.000 description 1
229920002472 Starch Polymers 0.000 description 1
FJWGYAHXMCUOOM-QHOUIDNNSA-N [(2s,3r,4s,5r,6r)-2-[(2r,3r,4s,5r,6s)-4,5-dinitrooxy-2-(nitrooxymethyl)-6-[(2r,3r,4s,5r,6s)-4,5,6-trinitrooxy-2-(nitrooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-3,5-dinitrooxy-6-(nitrooxymethyl)oxan-4-yl] nitrate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O)O[C@H]1[C@@H]([C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@@H](CO[N+]([O-])=O)O1)O[N+]([O-])=O)CO[N+](=O)[O-])[C@@H]1[C@@H](CO[N+]([O-])=O)O[C@@H](O[N+]([O-])=O)[C@H](O[N+]([O-])=O)[C@H]1O[N+]([O-])=O FJWGYAHXMCUOOM-QHOUIDNNSA-N 0.000 description 1
239000012736 aqueous medium Substances 0.000 description 1
229920002678 cellulose Polymers 0.000 description 1
239000001913 cellulose Substances 0.000 description 1
210000001072 colon Anatomy 0.000 description 1
238000011161 development Methods 0.000 description 1
238000010586 diagram Methods 0.000 description 1
229940079593 drug Drugs 0.000 description 1
230000000694 effects Effects 0.000 description 1
229920001249 ethyl cellulose Polymers 0.000 description 1
235000019325 ethyl cellulose Nutrition 0.000 description 1
210000001035 gastrointestinal tract Anatomy 0.000 description 1
239000007903 gelatin capsule Substances 0.000 description 1
230000036571 hydration Effects 0.000 description 1
238000006703 hydration reaction Methods 0.000 description 1
238000011534 incubation Methods 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
229920001220 nitrocellulos Polymers 0.000 description 1
229940079938 nitrocellulose Drugs 0.000 description 1
229920002689 polyvinyl acetate Polymers 0.000 description 1
239000011118 polyvinyl acetate Substances 0.000 description 1
239000008213 purified water Substances 0.000 description 1
238000011160 research Methods 0.000 description 1
239000002195 soluble material Substances 0.000 description 1
239000007921 spray Substances 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
238000003756 stirring Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Anesthesiology (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Medicinal Preparation (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Pens And Brushes (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

CA002302788A 1997-09-04 1998-09-02 Improvements in or relating to capsules Abandoned CA2302788A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB9718664.7		1997-09-04
GBGB9718664.7A GB9718664D0 (en)	1997-09-04	1997-09-04	Improvements in or relating to capsules
PCT/GB1998/002635 WO1999011246A1 (en)	1997-09-04	1998-09-02	Improvements in or relating to capsules

Publications (1)

Publication Number	Publication Date
CA2302788A1 true CA2302788A1 (en)	1999-03-11

Family

ID=10818455

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002302788A Abandoned CA2302788A1 (en)	1997-09-04	1998-09-02	Improvements in or relating to capsules

Country Status (8)

Country	Link
EP (1)	EP1009389A1 (pt)
JP (1)	JP2001514211A (pt)
AU (1)	AU734740B2 (pt)
BR (1)	BR9811753A (pt)
CA (1)	CA2302788A1 (pt)
GB (1)	GB9718664D0 (pt)
NZ (1)	NZ503164A (pt)
WO (1)	WO1999011246A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN105726460A (zh) *	2010-07-05	2016-07-06	雅戈泰克股份公司	剂型
WO2021176361A1 (en) *	2020-03-02	2021-09-10	Craft Health Pte Ltd	Method of manufacturing oral dosage forms for extended drug release
EP4633718A2 (en) *	2022-12-13	2025-10-22	Verily Life Sciences LLC	Ingestible device with self-orientation capability in an in vivo environment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4055178A (en) *	1976-03-10	1977-10-25	Harrigan Roy Major	Drug delivery device for preventing contact of undissolved drug with the stomach lining
DE3803482A1 (de) *	1988-02-05	1989-08-17	Lohmann Therapie Syst Lts	Schwimmfaehiges orales therapeutisches system
ATE90202T1 (de)	1989-02-16	1993-06-15	British Tech Group	Wirkstoffabgabevorrichtung.
US5198229A (en) *	1991-06-05	1993-03-30	Alza Corporation	Self-retaining gastrointestinal delivery device
GB9223172D0 (en) *	1992-11-05	1992-12-16	Scherer Corp R P	Capsule construction

1997
- 1997-09-04 GB GBGB9718664.7A patent/GB9718664D0/en not_active Ceased
1998
- 1998-09-02 JP JP2000508349A patent/JP2001514211A/ja active Pending
- 1998-09-02 EP EP98940458A patent/EP1009389A1/en not_active Withdrawn
- 1998-09-02 CA CA002302788A patent/CA2302788A1/en not_active Abandoned
- 1998-09-02 WO PCT/GB1998/002635 patent/WO1999011246A1/en not_active Ceased
- 1998-09-02 NZ NZ503164A patent/NZ503164A/en unknown
- 1998-09-02 AU AU88781/98A patent/AU734740B2/en not_active Ceased
- 1998-09-02 BR BR9811753-0A patent/BR9811753A/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU8878198A (en)	1999-03-22
NZ503164A (en)	2001-07-27
AU734740B2 (en)	2001-06-21
GB9718664D0 (en)	1997-11-05
JP2001514211A (ja)	2001-09-11
EP1009389A1 (en)	2000-06-21
BR9811753A (pt)	2001-11-27
WO1999011246A1 (en)	1999-03-11

Publication	Publication Date	Title
US5198229A (en)	1993-03-30	Self-retaining gastrointestinal delivery device
RU2104084C1 (ru)	1998-02-10	Капсула дозируемого выброса
JPH08505372A (ja)	1996-06-11	制御状態にある放出装置
US4034756A (en)	1977-07-12	Osmotically driven fluid dispenser
US4217898A (en)	1980-08-19	System with microporous reservoir having surface for diffusional delivery of agent
CA2007463C (en)	1995-01-17	Dispensing devices powered by hydrogel
US6303144B1 (en)	2001-10-16	Preparations with controlled release
EP0202159B1 (en)	1991-07-03	Drug delivery device which can be retained in the stomach for a controlled period of time
CZ288441B6 (en)	2001-06-13	Floating peroral therapeutic system
NO178426B (no)	1995-12-18	Legemiddelavgivelsesanordning for gastrisk kontrollert medikamentavgivelse
JPH11510066A (ja)	1999-09-07	個別ユニットの経口送り出し
WO1994009743A1 (en)	1994-05-11	Vented capsule
RU2094044C1 (ru)	1997-10-27	Капсула для орального введения с отсроченным импульсным выделением активного соединения
US5342624A (en)	1994-08-30	Dispensing device
ES2288165T3 (es)	2008-01-01	Sistemas de administracion de liberacion sostenida para solutos.
JPH09507058A (ja)	1997-07-15	投与装置からの材料の放出
JPS60237016A (ja)	1985-11-25	薬剤デイスペンサ−
AU734740B2 (en)	2001-06-21	Improvements in or relating to capsules
TW200418527A (en)	2004-10-01	Dosage form providing ascending release of liquid formulation
JPS6322014A (ja)	1988-01-29	胃内浮遊性持続型カプセル剤
JP4955888B2 (ja)	2012-06-20	ディスペンサーを備えて構成されるデバイス、及びそのデバイスを有するキット
AU5426094A (en)	1994-05-24	Capsule cap
JPWO1999040942A1 (ja)	2002-10-08	放出制御製剤

Legal Events

Date	Code	Title	Description
2000-11-21	EEER	Examination request
2003-09-02	FZDE	Discontinued