CA2388637A1 - Gene fgf-20 humain et produits d'expression genique - Google Patents
Gene fgf-20 humain et produits d'expression genique Download PDFInfo
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- CA2388637A1 CA2388637A1 CA002388637A CA2388637A CA2388637A1 CA 2388637 A1 CA2388637 A1 CA 2388637A1 CA 002388637 A CA002388637 A CA 002388637A CA 2388637 A CA2388637 A CA 2388637A CA 2388637 A1 CA2388637 A1 CA 2388637A1
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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Abstract
La présente invention concerne un facteur de croissance des fibroblastes humain (hFGF-20), des variants de ce dernier et des polynucléotides codant le FGF-20. L'invention se rapporte également à des agents diagnostiques et thérapeutiques liés aux polynucléotides et protéines de l'invention, y compris des sondes et des anticorps, à des procédés de traitement d'une maladie neurodégénérative telle que la maladie de Parkinson et à des procédés de traitement des troubles cochléaires, y compris les troubles entraînant une perte d'audition. L'invention concerne aussi le facteur de croissance des fibroblastes du rat (rFGF-20), des variants de ce dernier et des polynucléotides codant le rFGF-20.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16116299P | 1999-10-22 | 1999-10-22 | |
| US60/161,162 | 1999-10-22 | ||
| US18785600P | 2000-03-08 | 2000-03-08 | |
| US60/187,856 | 2000-03-08 | ||
| PCT/US2000/029237 WO2001031008A2 (fr) | 1999-10-22 | 2000-10-20 | Gene fgf-20 humain et produits d'expression genique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2388637A1 true CA2388637A1 (fr) | 2001-05-03 |
Family
ID=26857561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002388637A Abandoned CA2388637A1 (fr) | 1999-10-22 | 2000-10-20 | Gene fgf-20 humain et produits d'expression genique |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1224283A2 (fr) |
| JP (1) | JP2003512841A (fr) |
| AU (1) | AU1101901A (fr) |
| CA (1) | CA2388637A1 (fr) |
| WO (1) | WO2001031008A2 (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7253266B2 (en) | 1999-07-27 | 2007-08-07 | Curagen Corporation | Polypeptides of FGF-CX |
| US7056885B1 (en) | 1999-07-27 | 2006-06-06 | Curagen Corporation | Fibroblast growth factor and nucleic acids encoding same |
| WO2001068854A2 (fr) | 2000-03-13 | 2001-09-20 | Amgen, Inc. | Molecules s'apparentant au facteur de croissance des fibroblastes et leurs utilisations |
| GB2365869A (en) * | 2000-05-30 | 2002-02-27 | Smithkline Beecham Corp | SbgFGF-9a polynucleotides and polypeptides |
| WO2001092522A2 (fr) * | 2000-06-01 | 2001-12-06 | Eli Lilly And Company | Acides nucleiques et polypeptides humains fgf-20 |
| JP2004502418A (ja) * | 2000-07-03 | 2004-01-29 | キュラジェン コーポレイション | 新規の線維芽細胞増殖因子およびそれをコードする核酸 |
| US7189693B2 (en) | 2000-11-06 | 2007-03-13 | Curagen Corporation | Treatment of inflammatory bowel disease using fibroblast growth factor CX polypeptides |
| US6982250B2 (en) | 2000-11-06 | 2006-01-03 | Curagen Corporation | Methods of prevention and treatment of inflammatory bowel disease |
| US20020151496A1 (en) * | 2000-12-08 | 2002-10-17 | Bringmann Peter W. | Novel fibroblast growth factors |
| JP2005500035A (ja) * | 2001-06-15 | 2005-01-06 | キュラジェン コーポレイション | 新規線維芽細胞成長因子およびそれをコード化する核酸 |
| WO2004105787A1 (fr) * | 2003-05-28 | 2004-12-09 | The University Of Kyoto | Procedes d'utilisation d'associations de fgf-2 et fgf-20 pour traiter des affections du systeme nerveux central |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000054813A2 (fr) * | 1999-03-15 | 2000-09-21 | Chiron Corporation | Utilisation de vecteurs d'administration d'un gene recombinant pour le traitement ou la prévention des maladies de l'oeil |
| US7056885B1 (en) * | 1999-07-27 | 2006-06-06 | Curagen Corporation | Fibroblast growth factor and nucleic acids encoding same |
-
2000
- 2000-10-20 JP JP2001533989A patent/JP2003512841A/ja active Pending
- 2000-10-20 CA CA002388637A patent/CA2388637A1/fr not_active Abandoned
- 2000-10-20 WO PCT/US2000/029237 patent/WO2001031008A2/fr not_active Ceased
- 2000-10-20 EP EP00972344A patent/EP1224283A2/fr not_active Withdrawn
- 2000-10-20 AU AU11019/01A patent/AU1101901A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001031008A3 (fr) | 2002-03-07 |
| AU1101901A (en) | 2001-05-08 |
| EP1224283A2 (fr) | 2002-07-24 |
| WO2001031008A2 (fr) | 2001-05-03 |
| JP2003512841A (ja) | 2003-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |